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Aliases for PMS2P5 Gene

Aliases for PMS2P5 Gene

  • PMS1 Homolog 2, Mismatch Repair System Component Pseudogene 5 2 3 5
  • Postmeiotic Segregation Increased 2 Pseudogene 5 2 3
  • Postmeiotic Segregation Increased 2-Like 5 2 3
  • PMS2L5 3 4
  • PMS7 3 4
  • Putative Postmeiotic Segregation Increased 2 Pseudogene 5 4
  • Postmeiotic Segregation Increased Protein 4 4
  • Postmeiotic Segregation Increased Protein 7 4
  • PMS4 4

External Ids for PMS2P5 Gene

Previous HGNC Symbols for PMS2P5 Gene

  • PMS2L5

Previous GeneCards Identifiers for PMS2P5 Gene

  • GC07M094532
  • GC07P074308
  • GC07P074312

Summaries for PMS2P5 Gene

GeneCards Summary for PMS2P5 Gene

PMS2P5 (PMS1 Homolog 2, Mismatch Repair System Component Pseudogene 5) is a Pseudogene.

Additional gene information for PMS2P5 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PMS2P5 Gene

Genomics for PMS2P5 Gene

Regulatory Elements for PMS2P5 Gene

Enhancers for PMS2P5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H074635 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.9 -254.7 -254733 1 PKNOX1 FOXA2 ZFP64 ARID4B SIN3A FOS ZNF202 REST PPARG ZNF623 PMS2P3 STAG3L1 NSUN5P1 MIR590 SPDYE5 METTL27 GTF2IRD2 GTF2IRD2B LOC101926943 BUD23
GH07H074609 1.3 Ensembl ENCODE 11.8 -280.4 -280411 2 FOXA2 MLX ZFP64 ARID4B SIN3A ZNF2 YY1 FOS KLF7 ATF7 PMS2P5 PMS2P3 NSUN5P1 ENSG00000273069 GC07P074635
GH07H074586 1.4 Ensembl ENCODE dbSUPER 10.9 -303.4 -303444 2 HDAC1 HDGF PKNOX1 NFIB ZNF766 ZNF143 ATF7 RUNX3 IKZF2 SMARCA5 GTF2I PMS2P5 ENSG00000273069 GC07M074406
GH07H074616 1.2 Ensembl ENCODE dbSUPER 11.8 -273.2 -273221 1 HDAC1 ZNF687 L3MBTL2 ETV1 MAX ELF1 TFDP1 GATA3 POLR2A IKZF1 PMS2P5 ENSG00000273069 GC07P074635
GH07H074627 1.4 Ensembl ENCODE dbSUPER 9 -262.6 -262589 2 ARID4B THRB RAD21 THAP11 HMG20B SP5 CEBPB USF2 KAT8 NFIL3 GTF2I GTF2IRD1 PMS2P5 GC07P074635 ENSG00000273069
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PMS2P5 on UCSC Golden Path with GeneCards custom track

Promoters for PMS2P5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000213694 -368 2401 ATF1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 GLIS2 ATF7 SP3 NFYC

Genomic Location for PMS2P5 Gene

Chromosome:
7
Start:
74,890,768 bp from pter
End:
74,921,138 bp from pter
Size:
30,371 bases
Orientation:
Plus strand

Genomic View for PMS2P5 Gene

Genes around PMS2P5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PMS2P5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PMS2P5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PMS2P5 Gene

Proteins for PMS2P5 Gene

  • Protein details for PMS2P5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MQ11-PM2P5_HUMAN
    Recommended name:
    Postmeiotic segregation increased 2-like protein 5
    Protein Accession:
    A8MQ11

    Protein attributes for PMS2P5 Gene

    Size:
    134 amino acids
    Molecular mass:
    15170 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Encoded by one of the numerous copies of postmeiotic segregation increased 2-like genes scattered in the q11-q22 region of the chromosome 7.

neXtProt entry for PMS2P5 Gene

Post-translational modifications for PMS2P5 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PMS2P5 Gene

Domains & Families for PMS2P5 Gene

Protein Domains for PMS2P5 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A8MQ11

UniProtKB/Swiss-Prot:

PM2P5_HUMAN :
  • Belongs to the DNA mismatch repair MutL/HexB family.
Family:
  • Belongs to the DNA mismatch repair MutL/HexB family.
genes like me logo Genes that share domains with PMS2P5: view

No data available for Gene Families for PMS2P5 Gene

Function for PMS2P5 Gene

Phenotypes From GWAS Catalog for PMS2P5 Gene

Gene Ontology (GO) - Molecular Function for PMS2P5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003697 single-stranded DNA binding IBA --
GO:0016887 ATPase activity IBA --
genes like me logo Genes that share ontologies with PMS2P5: view
genes like me logo Genes that share phenotypes with PMS2P5: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for PMS2P5
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PMS2P5 Gene

Localization for PMS2P5 Gene

Gene Ontology (GO) - Cellular Components for PMS2P5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032389 MutLalpha complex IBA --
genes like me logo Genes that share ontologies with PMS2P5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for PMS2P5 Gene

Pathways & Interactions for PMS2P5 Gene

SuperPathways for PMS2P5 Gene

No Data Available

Interacting Proteins for PMS2P5 Gene

Selected Interacting proteins: A8MQ11-PM2P5_HUMAN for PMS2P5 Gene via IID

Gene Ontology (GO) - Biological Process for PMS2P5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006298 mismatch repair IBA --
GO:0016446 somatic hypermutation of immunoglobulin genes IBA --
genes like me logo Genes that share ontologies with PMS2P5: view

No data available for Pathways by source and SIGNOR curated interactions for PMS2P5 Gene

Drugs & Compounds for PMS2P5 Gene

No Compound Related Data Available

Transcripts for PMS2P5 Gene

mRNA/cDNA for PMS2P5 Gene

(1) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(78) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PMS2P5 Gene

Postmeiotic segregation increased 2 pseudogene 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for PMS2P5
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for PMS2P5 Gene

No ASD Table

Relevant External Links for PMS2P5 Gene

GeneLoc Exon Structure for
PMS2P5
ECgene alternative splicing isoforms for
PMS2P5

Expression for PMS2P5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PMS2P5 Gene

NURSA nuclear receptor signaling pathways regulating expression of PMS2P5 Gene:

PMS2P5

SOURCE GeneReport for Unigene cluster for PMS2P5 Gene:

Hs.647025
genes like me logo Genes that share expression patterns with PMS2P5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PMS2P5 Gene

Orthologs for PMS2P5 Gene

Evolution for PMS2P5 Gene

ENSEMBL:
Gene Tree for PMS2P5 (if available)
TreeFam:
Gene Tree for PMS2P5 (if available)

No data available for Orthologs for PMS2P5 Gene

Paralogs for PMS2P5 Gene

(9) SIMAP similar genes for PMS2P5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PMS2P5: view

No data available for Paralogs for PMS2P5 Gene

Variants for PMS2P5 Gene

Sequence variations from dbSNP and Humsavar for PMS2P5 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10230314 -- 74,893,085(+) cggtg(A/G)aaccc intron-variant
rs10230318 -- 74,893,100(+) tctac(A/T)aaaaa intron-variant
rs10259816 -- 74,893,130(+) atggt(C/G)gtggg intron-variant
rs10259874 -- 74,892,991(+) tgggc(A/G)tggtg intron-variant
rs1060839 -- 74,915,406(+) ctcac(A/G)cttgt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PMS2P5 Gene

Variant ID Type Subtype PubMed ID
esv24294 CNV gain 19812545
esv2761338 CNV gain 21179565
esv3416980 CNV duplication 20981092
nsv1032137 CNV gain 25217958
nsv1112934 CNV deletion 24896259
nsv1139900 CNV duplication 24896259
nsv482104 CNV gain 20164927
nsv510089 OTHER sequence alteration 20534489
nsv7402 OTHER inversion 18451855
nsv8144 CNV gain+loss 18304495
nsv950551 CNV deletion 24416366
nsv970533 CNV duplication 23825009
nsv971037 CNV duplication 23825009
nsv981528 CNV duplication 23825009
nsv981665 CNV duplication 23825009
nsv981666 CNV duplication 23825009

Relevant External Links for PMS2P5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PMS2P5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PMS2P5 Gene

Disorders for PMS2P5 Gene

Relevant External Links for PMS2P5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PMS2P5

No disorders were found for PMS2P5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PMS2P5 Gene

Publications for PMS2P5 Gene

  1. Genomic organization of the human PMS2 gene family. (PMID: 8586419) Nicolaides NC … Kinzler KW (Genomics 1995) 2 3 60
  2. Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes. (PMID: 7980603) Horii A … Nakamura Y (Biochemical and biophysical research communications 1994) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  4. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 4 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for PMS2P5 Gene

Sources for PMS2P5 Gene

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