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Aliases for PMS2P5 Gene

Aliases for PMS2P5 Gene

  • Postmeiotic Segregation Increased 2 Pseudogene 5 2 3
  • Postmeiotic Segregation Increased 2-Like 5 2 3
  • PMS2L5 3 4
  • PMS7 3 4
  • Putative Postmeiotic Segregation Increased 2 Pseudogene 5 4
  • Postmeiotic Segregation Increased Protein 4 4
  • Postmeiotic Segregation Increased Protein 7 4
  • PMS4 4

External Ids for PMS2P5 Gene

Previous Symbols for PMS2P5 Gene

  • PMS2L5

Summaries for PMS2P5 Gene

GeneCards Summary for PMS2P5 Gene

PMS2P5 (Postmeiotic Segregation Increased 2 Pseudogene 5) is a Pseudogene. GO annotations related to this gene include ATPase activity and mismatched DNA binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PMS2P5 Gene

Genomics for PMS2P5 Gene

Genomic Location for PMS2P5 Gene

Start:
74,890,768 bp from pter
End:
74,921,138 bp from pter
Size:
30,371 bases
Orientation:
Plus strand

Genomic View for PMS2P5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PMS2P5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PMS2P5 Gene

No data available for Regulatory Elements for PMS2P5 Gene

Proteins for PMS2P5 Gene

  • Protein details for PMS2P5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MQ11-PM2P5_HUMAN
    Recommended name:
    Postmeiotic segregation increased 2-like protein 5
    Protein Accession:
    A8MQ11
    Secondary Accessions:

    Protein attributes for PMS2P5 Gene

    Size:
    134 amino acids
    Molecular mass:
    15170 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Encoded by one of the numerous copies of postmeiotic segregation increased 2-like genes scattered in the q11-q22 region of the chromosome 7

neXtProt entry for PMS2P5 Gene

Proteomics data for PMS2P5 Gene at MOPED

Post-translational modifications for PMS2P5 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PMS2P5 Gene

Domains for PMS2P5 Gene

Protein Domains for PMS2P5 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

PM2P5_HUMAN
Family:
  • Belongs to the DNA mismatch repair MutL/HexB family.:
    • A8MQ11
genes like me logo Genes that share domains with PMS2P5: view

No data available for Gene Families for PMS2P5 Gene

Function for PMS2P5 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for PMS2P5 Gene

Localization for PMS2P5 Gene

Gene Ontology (GO) - Cellular Components for PMS2P5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032300 mismatch repair complex IEA --
genes like me logo Genes that share ontologies with PMS2P5: view

Pathways for PMS2P5 Gene

SuperPathways for PMS2P5 Gene

No Data Available

Interacting Proteins for PMS2P5 Gene

Gene Ontology (GO) - Biological Process for PMS2P5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006298 mismatch repair IEA --
genes like me logo Genes that share ontologies with PMS2P5: view

No data available for Pathways by source for PMS2P5 Gene

Transcripts for PMS2P5 Gene

mRNA/cDNA for PMS2P5 Gene

(1) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(34) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PMS2P5 Gene

Postmeiotic segregation increased 2 pseudogene 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PMS2P5 Gene

No ASD Table

Relevant External Links for PMS2P5 Gene

GeneLoc Exon Structure for
PMS2P5
ECgene alternative splicing isoforms for
PMS2P5

Expression for PMS2P5 Gene

mRNA expression in normal human tissues for PMS2P5 Gene

SOURCE GeneReport for Unigene cluster for PMS2P5 Gene Hs.647025

genes like me logo Genes that share expressions with PMS2P5: view

Orthologs for PMS2P5 Gene

Evolution for PMS2P5 Gene

ENSEMBL:
Gene Tree for PMS2P5 (if available)
TreeFam:
Gene Tree for PMS2P5 (if available)

No data available for Orthologs for PMS2P5 Gene

Paralogs for PMS2P5 Gene

Selected SIMAP similar genes for PMS2P5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PMS2P5: view

No data available for Paralogs for PMS2P5 Gene

Variants for PMS2P5 Gene

Sequence variations from dbSNP and Humsavar for PMS2P5 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs8338 -- 74,900,931(+) CAGTT(C/T)CTTGA nc-transcript-variant, intron-variant
rs1060839 -- 74,915,406(+) ctcac(A/G)cttgt intron-variant
rs1061917 -- 74,897,986(+) TTCAG(A/G)ATGAT intron-variant
rs1635760 -- 74,897,061(-) ccagc(A/T)cttca intron-variant
rs1637338 -- 74,896,875(+) TAAAT(A/G)ATTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PMS2P5 Gene

Variant ID Type Subtype PubMed ID
dgv2100e1 CNV Complex 17122850
nsv888380 CNV Loss 21882294
essv21300 CNV CNV 17122850
nsv888381 CNV Gain 21882294
nsv7402 OTHER Inversion 18451855
nsv888382 CNV Gain 21882294
esv24294 CNV Gain 19812545
nsv482104 CNV Gain 20164927
nsv8144 CNV Gain+Loss 18304495
nsv510089 CNV Loss 20534489
esv2734671 CNV Deletion 23290073

Relevant External Links for PMS2P5 Gene

HapMap Linkage Disequilibrium report
PMS2P5

Disorders for PMS2P5 Gene

No disorders were found for PMS2P5 Gene.

No data available for UniProtKB/Swiss-Prot for PMS2P5 Gene

Publications for PMS2P5 Gene

  1. Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes. (PMID: 7980603) Horii A. … Nakamura Y. (Biochem. Biophys. Res. Commun. 1994) 3 4
  2. Genomic organization of the human PMS2 gene family. (PMID: 8586419) Nicolaides N.C. … Kinzler K.W. (Genomics 1995) 2 3
  3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4

Products for PMS2P5 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate PMS2P5
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for PMS2P5
    • Block miRNA regulation of PMS2P5 using miScript Target Protectors

    Sources for PMS2P5 Gene

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