Free for academic non-profit institutions. Other users need a Commercial license

Aliases for PMS2P5 Gene

Aliases for PMS2P5 Gene

  • PMS1 Homolog 2, Mismatch Repair System Component Pseudogene 5 2 3 5
  • Postmeiotic Segregation Increased 2 Pseudogene 5 2 3
  • Postmeiotic Segregation Increased 2-Like 5 2 3
  • PMS2L5 3 4
  • PMS7 3 4
  • Putative Postmeiotic Segregation Increased 2 Pseudogene 5 4
  • Postmeiotic Segregation Increased Protein 4 4
  • Postmeiotic Segregation Increased Protein 7 4
  • PMS4 4

External Ids for PMS2P5 Gene

Previous HGNC Symbols for PMS2P5 Gene

  • PMS2L5

Previous GeneCards Identifiers for PMS2P5 Gene

  • GC07M094532
  • GC07P074308
  • GC07P074312

Summaries for PMS2P5 Gene

GeneCards Summary for PMS2P5 Gene

PMS2P5 (PMS1 Homolog 2, Mismatch Repair System Component Pseudogene 5) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PMS2P5 Gene

Genomics for PMS2P5 Gene

Regulatory Elements for PMS2P5 Gene

Promoters for PMS2P5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around PMS2P5 on UCSC Golden Path with GeneCards custom track

Genomic Location for PMS2P5 Gene

Chromosome:
7
Start:
74,890,768 bp from pter
End:
74,921,138 bp from pter
Size:
30,371 bases
Orientation:
Plus strand

Genomic View for PMS2P5 Gene

Genes around PMS2P5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PMS2P5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PMS2P5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PMS2P5 Gene

Proteins for PMS2P5 Gene

  • Protein details for PMS2P5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MQ11-PM2P5_HUMAN
    Recommended name:
    Postmeiotic segregation increased 2-like protein 5
    Protein Accession:
    A8MQ11

    Protein attributes for PMS2P5 Gene

    Size:
    134 amino acids
    Molecular mass:
    15170 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Encoded by one of the numerous copies of postmeiotic segregation increased 2-like genes scattered in the q11-q22 region of the chromosome 7.

neXtProt entry for PMS2P5 Gene

Proteomics data for PMS2P5 Gene at MOPED

Post-translational modifications for PMS2P5 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PMS2P5 Gene

Domains & Families for PMS2P5 Gene

Protein Domains for PMS2P5 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A8MQ11

UniProtKB/Swiss-Prot:

PM2P5_HUMAN :
  • Belongs to the DNA mismatch repair MutL/HexB family.
Family:
  • Belongs to the DNA mismatch repair MutL/HexB family.
genes like me logo Genes that share domains with PMS2P5: view

No data available for Gene Families for PMS2P5 Gene

Function for PMS2P5 Gene

Gene Ontology (GO) - Molecular Function for PMS2P5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003697 single-stranded DNA binding IBA --
genes like me logo Genes that share ontologies with PMS2P5: view
genes like me logo Genes that share phenotypes with PMS2P5: view

Animal Model Products

  • Taconic Biosciences Mouse Models for PMS2P5

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PMS2P5 Gene

Localization for PMS2P5 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PMS2P5 Gene

Pathways & Interactions for PMS2P5 Gene

SuperPathways for PMS2P5 Gene

No Data Available

Interacting Proteins for PMS2P5 Gene

Gene Ontology (GO) - Biological Process for PMS2P5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016446 somatic hypermutation of immunoglobulin genes IBA --
genes like me logo Genes that share ontologies with PMS2P5: view

No data available for Pathways by source and SIGNOR curated interactions for PMS2P5 Gene

Drugs & Compounds for PMS2P5 Gene

No Compound Related Data Available

Transcripts for PMS2P5 Gene

mRNA/cDNA for PMS2P5 Gene

(1) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(34) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PMS2P5 Gene

Postmeiotic segregation increased 2 pseudogene 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PMS2P5 Gene

No ASD Table

Relevant External Links for PMS2P5 Gene

GeneLoc Exon Structure for
PMS2P5
ECgene alternative splicing isoforms for
PMS2P5

Expression for PMS2P5 Gene

mRNA expression in normal human tissues for PMS2P5 Gene

SOURCE GeneReport for Unigene cluster for PMS2P5 Gene Hs.647025

genes like me logo Genes that share expression patterns with PMS2P5: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for PMS2P5 Gene

Orthologs for PMS2P5 Gene

Evolution for PMS2P5 Gene

ENSEMBL:
Gene Tree for PMS2P5 (if available)
TreeFam:
Gene Tree for PMS2P5 (if available)

No data available for Orthologs for PMS2P5 Gene

Paralogs for PMS2P5 Gene

(9) SIMAP similar genes for PMS2P5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PMS2P5: view

No data available for Paralogs for PMS2P5 Gene

Variants for PMS2P5 Gene

Sequence variations from dbSNP and Humsavar for PMS2P5 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs8338 -- 74,900,931(+) CAGTT(C/T)CTTGA intron-variant, nc-transcript-variant
rs231628 -- 74,913,810(+) GATTA(C/T)CATGT intron-variant
rs1060839 -- 74,915,406(+) ctcac(A/G)cttgt intron-variant
rs1061917 -- 74,897,986(+) TTCAG(A/G)ATGAT intron-variant
rs1635760 -- 74,897,061(-) ccagc(A/T)cttca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PMS2P5 Gene

Variant ID Type Subtype PubMed ID
dgv2100e1 CNV Complex 17122850
nsv888380 CNV Loss 21882294
essv21300 CNV CNV 17122850
nsv888381 CNV Gain 21882294
nsv7402 OTHER Inversion 18451855
nsv888382 CNV Gain 21882294
esv24294 CNV Gain 19812545
nsv482104 CNV Gain 20164927
nsv8144 CNV Gain+Loss 18304495
nsv510089 CNV Loss 20534489
esv2734671 CNV Deletion 23290073

Relevant External Links for PMS2P5 Gene

HapMap Linkage Disequilibrium report
PMS2P5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PMS2P5 Gene

Disorders for PMS2P5 Gene

Relevant External Links for PMS2P5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PMS2P5

No disorders were found for PMS2P5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PMS2P5 Gene

Publications for PMS2P5 Gene

  1. Genomic organization of the human PMS2 gene family. (PMID: 8586419) Nicolaides N.C. … Kinzler K.W. (Genomics 1995) 2 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3
  4. Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes. (PMID: 7980603) Horii A. … Nakamura Y. (Biochem. Biophys. Res. Commun. 1994) 3

Products for PMS2P5 Gene

Sources for PMS2P5 Gene

Back to Top

Content