Aliases for PLS3 Gene
Aliases for PLS3 Gene
External Ids for PLS3 Gene
- HGNC: 9091
- Entrez Gene: 5358
- Ensembl: ENSG00000102024
- OMIM: 300131
- UniProtKB: P13797
Previous GeneCards Identifiers for PLS3 Gene
- GC0XP109814
- GC0XP111920
- GC0XP112831
- GC0XP113559
- GC0XP114618
- GC0XP114795
- GC0XP104379
Summaries for PLS3 Gene
-
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
GeneCards Summary for PLS3 Gene
PLS3 (Plastin 3) is a Protein Coding gene. Diseases associated with PLS3 include Bone Mineral Density Quantitative Trait Locus 18 and Sezary's Disease. Gene Ontology (GO) annotations related to this gene include calcium ion binding and actin binding. An important paralog of this gene is LCP1.
UniProtKB/Swiss-Prot for PLS3 Gene
-
Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. May play a role in the regulation of bone development.
Additional gene information for PLS3 Gene
- Monarch Initiative
- Search for PLS3 at DataMed
- Search for PLS3 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PLS3 Gene
Genomics for PLS3 Gene
GeneHancer (GH) Regulatory Elements for PLS3 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH0XI115559 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 565.1 | +1.2 | 1169 | 5.7 | PKNOX1 FOXA2 ARNT ARID4B SIN3A FEZF1 YY1 GLIS2 ZNF213 FOS | PLS3 PLS3-AS1 LRCH2 API5P1 | |
GH0XI115591 | Promoter/Enhancer | 1.6 | EPDnew Ensembl ENCODE | 550.3 | +32.5 | 32526 | 4.6 | SCRT1 SRF TAF1 ZNF189 JUN ZNF398 PRDM6 POLR2A SCRT2 IKZF2 | PLS3 PIR39078 PLS3-AS1 | |
GH0XI115581 | Enhancer | 0.8 | Ensembl ENCODE | 0.3 | +22.3 | 22326 | 2.9 | ZNF639 PKNOX1 MZF1 OSR2 PRDM6 IKZF1 IKZF2 RUNX3 PRDM1 TRIM28 | PLS3-AS1 PLS3 PIR39078 | |
GH0XI115613 | Enhancer | 1.2 | FANTOM5 Ensembl ENCODE | 0.2 | +55.3 | 55287 | 4.3 | SIN3A FEZF1 BATF IRF4 ZNF366 ATF7 ETV6 FOS IKZF2 RUNX3 | PIR39078 PLS3-AS1 PLS3 | |
GH0XI115604 | Enhancer | 0.6 | ENCODE | 0.3 | +42.3 | 42314 | 0.2 | ZBTB21 JUN CEBPB ZEB1 ZNF335 PRDM6 ZNF366 ZNF629 WT1 SP7 | PIR39078 PLS3-AS1 PLS3 |
Regulatory Element Products
Genomic Locations for PLS3 Gene
- chrX:115,560,850-115,650,861
- (GRCh38/hg38)
- Size:
- 90,012 bases
- Orientation:
- Plus strand
- chrX:114,795,177-114,885,181
- (GRCh37/hg19)
Genomic View for PLS3 Gene
- Cytogenetic band:
-
- Xq23 by Ensembl
- Xq23 by Entrez Gene
- Xq23 by HGNC


RefSeq DNA sequence for PLS3 Gene
Proteins for PLS3 Gene
-
Protein details for PLS3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P13797-PLST_HUMAN
- Recommended name:
- Plastin-3
- Protein Accession:
- P13797
- A8K579
- B1AQ09
- B4DGB4
- B7Z6M1
- Q86YI6
Protein attributes for PLS3 Gene
- Size:
- 630 amino acids
- Molecular mass:
- 70811 Da
- Quaternary structure:
-
- Monomer.
- SequenceCaution:
-
- Sequence=CAI39884.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for PLS3 Gene
Post-translational modifications for PLS3 Gene
- Ubiquitination at isoforms=252, Lys59, isoforms=2, 3100, Lys168, isoforms=2, 3300, isoforms=2, 3382, and isoforms=2, 3437
Other Protein References for PLS3 Gene
Antibody Products
- Novus Biologicals Antibodies for PLS3
-
Abcam antibodies for PLS3
-
Cloud-Clone Corp. Antibodies for PLS3
- Invitrogen Antibodies for PLS3
- GeneTex PLS3 antibody for PLS3
-
Santa Cruz Biotechnology (SCBT) Antibodies for PLS3
- Sino Biological Antibodies for PLS3
Protein Products
-
OriGene Purified Proteins for PLS3
- Search Origene for MassSpec and Protein Over-expression Lysates for PLS3
- Origene Custom Protein Services for PLS3
- Novus Biologicals proteins for PLS3
- Sino Biological Recombinant Proteins for PLS3
- Browse Sino Biological Cell Lysates
-
Cloud-Clone Corp. Proteins for PLS3
- Search GeneTex for Proteins for PLS3
-
Abcam proteins for PLS3
Assay Products
- antibodies-online: Search results for available PLS3 related products ranked by validation data
No data available for DME Specific Peptides for PLS3 Gene
Domains & Families for PLS3 Gene
Gene Families for PLS3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for PLS3 Gene
Suggested Antigen Peptide Sequences for PLS3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for PLS3 Gene
Function for PLS3 Gene
Molecular function for PLS3 Gene
- UniProtKB/Swiss-Prot Function:
- Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. May play a role in the regulation of bone development.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005509 | calcium ion binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO:0051015 | actin filament binding | IBA | -- |
Phenotypes for PLS3 Gene
- MGI mutant phenotypes for PLS3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PLS3:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability in esophageal squamous lineage
- Increased shRNA abundance (Z-score > 2)
- Decreased POU5F1-GFP protein expression
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased cell migration
- Increased cilium length after serum starvation
- Increased cilium length
Animal Models for PLS3 Gene
- MGI Knock Outs for PLS3:
-
- Pls3 tm1a(EUCOMM)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PLS3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for PLS3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
- Search ViGene Biosciences for PLS3
CRISPR Products
-
OriGene CRISPR knockouts for PLS3
- genomics-online: gRNA clones - Search results for available PLS3 gene related products
- Applied Biological Materials CRISPR for PLS3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PLS3
- GenScript: Design CRISPR guide RNA sequences for PLS3
miRNA for PLS3 Gene
- miRTarBase miRNAs that target PLS3
-
- hsa-mir-1-3p (MIRT023553)
- hsa-mir-215-5p (MIRT024836)
- hsa-mir-192-5p (MIRT026136)
- hsa-mir-148b-5p (MIRT038184)
- hsa-mir-193b-3p (MIRT041457)
- hsa-mir-320a (MIRT044656)
- hsa-mir-125a-5p (MIRT045702)
- hsa-mir-186-5p (MIRT240846)
- hsa-mir-6507-5p (MIRT240852)
- hsa-mir-3653-3p (MIRT329645)
- hsa-mir-3658 (MIRT329646)
- hsa-mir-218-5p (MIRT439945)
miRNA Products
- Search ViGene Biosciences for PLS3
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for PLS3
- Browse OriGene Inhibitory RNA Products For PLS3
- genomics-online: shRNA clones - Search results for available PLS3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
Clone Products
-
OriGene ORF clones in human for PLS3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PLS3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PLS3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PLS3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PLS3 gene related products
- orf clones - Search results for available PLS3 gene related products
- Applied Biological Materials Clones for PLS3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for PLS3
-
ViGene Biosciences adenoviral particle packaged cDNA for PLS3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PLS3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for PLS3 Gene
Localization for PLS3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PLS3 Gene
- Cytoplasm.
- Cytosol (3)
- Plasma membrane (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IBA | -- |
GO:0005829 | cytosol | IDA | -- |
GO:0005884 | actin filament | IBA | -- |
GO:0005886 | plasma membrane | IDA | -- |
GO:0032432 | actin filament bundle | IBA | -- |
Pathways & Interactions for PLS3 Gene
Interacting Proteins for PLS3 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0051017 | actin filament bundle assembly | IBA | -- |
GO:0051639 | actin filament network formation | IBA | -- |
GO:0051764 | actin crosslink formation | IBA | -- |
GO:0060348 | bone development | IMP | 24088043 |
No data available for Pathways by source and SIGNOR curated interactions for PLS3 Gene
Transcripts for PLS3 Gene
mRNA/cDNA for PLS3 Gene
- (6) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (531) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for PLS3
- genomics-online: gRNA clones - Search results for available PLS3 gene related products
- Applied Biological Materials CRISPR for PLS3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PLS3
- GenScript: Design CRISPR guide RNA sequences for PLS3
miRNA Products
- Search ViGene Biosciences for PLS3
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for PLS3
- Browse OriGene Inhibitory RNA Products For PLS3
- genomics-online: shRNA clones - Search results for available PLS3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
Clone Products
-
OriGene ORF clones in human for PLS3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PLS3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PLS3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PLS3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PLS3 gene related products
- orf clones - Search results for available PLS3 gene related products
- Applied Biological Materials Clones for PLS3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for PLS3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Inner Cell Mass (Early Embryonic Tissues)
- Inner Cell Mass Cells Inner Cell Mass
-
Testis (Reproductive System)
- Testicular Interstitial Cells Testis Interstitium
-
Gonad (Reproductive System)
- Primordial Germ Cells Primitive Gonad
-
Peripheral Nervous System (Nervous System)
- Schwann Precursor Cells Peripheral Nerve Domain
- Brain (Nervous System)
- Neurons
-
Uterus (Reproductive System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Kidney (Urinary System)
-
Esophagus (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for PLS3 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PLS3 Gene
NURSA nuclear receptor signaling pathways regulating expression of PLS3 Gene:
PLS3SOURCE GeneReport for Unigene cluster for PLS3 Gene:
Hs.496622mRNA Expression by UniProt/SwissProt for PLS3 Gene:
P13797-PLST_HUMANEvidence on tissue expression from TISSUES for PLS3 Gene
- Nervous system(5)
- Skin(4.7)
- Kidney(4.6)
- Liver(4.4)
- Lung(3.7)
- Intestine(2.4)
- Blood(2.2)
- Spleen(2.2)
- Thyroid gland(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for PLS3 Gene
- mesoderm
- skeleton
- head
- jaw
- mandible
- maxilla
- mouth
- neck
- skull
- chest wall
- clavicle
- rib
- rib cage
- scapula
- sternum
- pelvis
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for PLS3
-
OriGene qPCR primer pairs and template standards for PLS3
- genomics-online: primer clones - Search results for available PLS3 gene related products
Orthologs for PLS3 Gene
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | PLS3 34 33 |
|
OneToOne | |
oppossum (Monodelphis domestica) |
Mammalia | PLS3 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | PLS3 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | PLS3 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Pls3 33 |
|
||
mouse (Mus musculus) |
Mammalia | Pls3 33 16 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | PLS3 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | PLS3 34 33 |
|
OneToOne | |
lizard (Anolis carolinensis) |
Reptilia | PLS3 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | pls3 33 |
|
||
Str.17623 33 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | MGC68681 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | pls3 33 34 |
|
||
fruit fly (Drosophila melanogaster) |
Insecta | Fim 35 34 |
|
||
worm (Caenorhabditis elegans) |
Secernentea | Y104H12BR.1 35 |
|
|
|
Y73B3B.1 35 34 |
|
||||
plst-1 34 |
|
ManyToMany | |||
Y104H12BL.1 35 |
|
|
|||
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SAC6 34 36 |
|
OneToMany | |
thale cress (Arabidopsis thaliana) |
eudicotyledons | AT5G48460 33 |
|
||
rice (Oryza sativa) |
Liliopsida | Os01g0514600 33 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8022 34 |
|
OneToMany | |
sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4644 33 |
|
- Species where no ortholog for PLS3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for PLS3 Gene
(2) SIMAP similar genes for PLS3 Gene using alignment to 9 proteins:
Variants for PLS3 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for PLS3 Gene
- PLST_HUMAN-P13797
- Genetic variations in PLS3 define the bone mineral density quantitative trait locus 18 (BMND18) [MIM:300910]. Variance in bone mineral density influences bone mass, contributes to size determination in the general population, and is a susceptibility factor for osteoporotic fractures.
SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs140121121 | association, Bone mineral density quantitative trait locus 18 | 115,629,281(+) | T/A | coding_sequence_variant, synonymous_variant | |
rs397518421 | association, Bone mineral density quantitative trait locus 18 | 115,646,495(+) | C/T | coding_sequence_variant, stop_gained | |
rs397518463 | association, Bone mineral density quantitative trait locus 18 | 115,622,405(+) | TTT/TT | coding_sequence_variant, frameshift, intron_variant | |
VAR_035462 | A breast cancer sample | p.Asp488Ala | |||
rs1000058798 | -- | 115,636,156(+) | T/C | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2666518 | CNV | deletion | 23128226 |
esv33994 | CNV | gain+loss | 17666407 |
esv3559212 | CNV | deletion | 23714750 |
esv3577051 | CNV | gain | 25503493 |
Additional Variant Information for PLS3 Gene
Disorders for PLS3 Gene

(5) MalaCards diseases for PLS3 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
Disorder | Aliases | PubMed IDs |
---|---|---|
bone mineral density quantitative trait locus 18 |
|
|
sezary's disease |
|
|
juvenile spinal muscular atrophy |
|
|
osteogenesis imperfecta, type i |
|
|
osteoporosis |
|
|
UniProtKB/Swiss-Prot
PLST_HUMAN- Osteoporosis (OSTEOP) [MIM:166710]: A systemic skeletal disorder characterized by decreased bone mass and deterioration of bone microarchitecture without alteration in the composition of bone. The result is fragile bones and an increased risk of fractures, even after minimal trauma. Osteoporosis is a chronic condition of multifactorial etiology and is usually clinically silent until a fracture occurs. {ECO:0000269 PubMed:24088043}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Additional Disease Information for PLS3
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for PLS3 Gene
Publications for PLS3 Gene
- Human plastin genes. Comparative gene structure, chromosome location, and differential expression in normal and neoplastic cells. (PMID: 8428952) Lin CS … Leavitt J (The Journal of biological chemistry 1993) 2 3 4 58
- Correction of the N-terminal sequences of the human plastin isoforms by using anchored polymerase chain reaction: identification of a potential calcium-binding domain. (PMID: 2378651) Lin CS … Leavitt J (Molecular and cellular biology 1990) 3 4 22 58
- PLS3 mutations in X-linked osteoporosis with fractures. (PMID: 24088043) van Dijk FS … Pals G (The New England journal of medicine 2013) 3 4 58
- Expression of T-plastin, FoxP3 and other tumor-associated markers by leukemic T-cells of cutaneous T-cell lymphoma. (PMID: 18569641) Capriotti E … Hess AD (Leukemia & lymphoma 2008) 3 22 58
- Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement. (PMID: 15741236) Giganti A … Friederich E (Journal of cell science 2005) 3 22 58
Products for PLS3 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PLS3
- Search Origene for MassSpec and Protein Over-expression Lysates for PLS3
- Origene Custom Protein Services for PLS3
- Origene shrna and RNAi products in human, mouse, rat for PLS3
- Browse OriGene Inhibitory RNA Products For PLS3
- OriGene qPCR primer pairs and template standards for PLS3
- OriGene qPCR primer pairs for PLS3
- OriGene CRISPR knockouts for PLS3
- OriGene ORF clones in human for PLS3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PLS3
- GenScript: Next-day shipping of latest version cDNA ORF clones for PLS3 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for PLS3
- GenScript Custom Assay Services for PLS3
- GenScript Custom overexpressing Cell Line Services for PLS3
- GenScript: Design CRISPR guide RNA sequences for PLS3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for PLS3
- Sino Biological Human cDNA Clone for PLS3
- Sino Biological Recombinant Proteins for PLS3
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for PLS3
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for PLS3
- Novus Biologicals proteins for PLS3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for PLS3
- Abcam proteins for PLS3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Cloud-Clone Corp. Antibodies for PLS3
- Cloud-Clone Corp. Proteins for PLS3
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for PLS3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for PLS3
- VectorBuilder custom plasmid, inducible vectors for PLS3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PLS3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 61 available PLS3 Antibodies ranked by validation data
- Compare Top PLS3 Antibodies
- Quality Products:
- antibodies-online: Search results for available PLS3 related products ranked by validation data
- antibodies-online: Search results for 14 available PLS3 Proteins ranked by validation data
- Compare Top PLS3 Proteins
- GeneTex PLS3 antibody for PLS3
- Search GeneTex for Proteins for PLS3
- ViGene Biosciences adenoviral particle packaged cDNA for PLS3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PLS3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
- Search ViGene Biosciences for PLS3
- Santa Cruz Biotechnology (SCBT) Antibodies for PLS3
- Search Santa Cruz Biotechnology (SCBT) for PLS3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PLS3
- Horizon Cell Lines for PLS3
- genomics-online: cdna clones - Search results for available PLS3 gene related products
- orf clones - Search results for available PLS3 gene related products
- genomics-online: gRNA clones - Search results for available PLS3 gene related products
- genomics-online: primer clones - Search results for available PLS3 gene related products
- genomics-online: shRNA clones - Search results for available PLS3 gene related products
Sources for PLS3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew