Aliases for PLS3 Gene
Aliases for PLS3 Gene
External Ids for PLS3 Gene
- HGNC: 9091
- Entrez Gene: 5358
- Ensembl: ENSG00000102024
- OMIM: 300131
- UniProtKB: P13797
Previous GeneCards Identifiers for PLS3 Gene
- GC0XP109814
- GC0XP111920
- GC0XP112831
- GC0XP113559
- GC0XP114618
- GC0XP114795
- GC0XP104379
Summaries for PLS3 Gene
-
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
GeneCards Summary for PLS3 Gene
PLS3 (Plastin 3) is a Protein Coding gene. Diseases associated with PLS3 include Bone Mineral Density Qtl18, Osteoporosis and X-Linked Osteoporosis With Fractures. GO annotations related to this gene include calcium ion binding and actin binding. An important paralog of this gene is PLS1.
UniProtKB/Swiss-Prot for PLS3 Gene
-
Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. May play a role in the regulation of bone development.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PLS3 Gene
Genomics for PLS3 Gene
Regulatory Elements for PLS3 Gene
Enhancers for PLS3 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around PLS3 on UCSC Golden Path with GeneCards custom track
Promoters for PLS3 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around PLS3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for PLS3 Gene
- Chromosome:
- X
- Start:
- 115,560,850 bp from pter
- End:
- 115,650,861 bp from pter
- Size:
- 90,012 bases
- Orientation:
- Plus strand
Genomic View for PLS3 Gene
Genes around PLS3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq23 by Ensembl
- Xq23 by Entrez Gene
- Xq23 by HGNC
PLS3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PLS3 Gene
Proteins for PLS3 Gene
-
Protein details for PLS3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P13797-PLST_HUMAN
- Recommended name:
- Plastin-3
- Protein Accession:
- P13797
- A8K579
- B1AQ09
- B4DGB4
- B7Z6M1
- Q86YI6
Protein attributes for PLS3 Gene
- Size:
- 630 amino acids
- Molecular mass:
- 70811 Da
- Quaternary structure:
-
- Monomer.
- SequenceCaution:
-
- Sequence=CAI39884.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for PLS3 Gene
Post-translational modifications for PLS3 Gene
Other Protein References for PLS3 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for PLS3
- Novus Biologicals Antibodies for PLS3
-
Cloud-Clone Corp. Antibodies for PLS3
- Invitrogen Antibodies for PLS3
- antibodies-online Antibodies for PLS3: See all 50
- GeneTex PLS3 antibody for PLS3
-
Santa Cruz Biotechnology (SCBT) Antibodies for PLS3
Protein Products
-
OriGene Purified Proteins for PLS3
- Search Origene for MassSpec and Protein Over-expression Lysates for PLS3
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- Novus Biologicals proteins for PLS3
- Sino Biological Recombinant Proteins for PLS3
- Browse Sino Biological Cell Lysates
-
Cloud-Clone Corp. Proteins for PLS3
- antibodies-online Proteins for PLS3: See all 15
- Search antibodies-online for peptides
- Search GeneTex for Proteins for PLS3
Assay Products
No data available for DME Specific Peptides for PLS3 Gene
Domains & Families for PLS3 Gene
Gene Families for PLS3 Gene
Protein Domains for PLS3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PLS3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P13797- Domain:
-
- Contains 2 actin-binding domains.
- Contains 4 CH (calponin-homology) domains.
- Contains 2 EF-hand domains.
Function for PLS3 Gene
Molecular function for PLS3 Gene
- UniProtKB/Swiss-Prot Function:
- Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. May play a role in the regulation of bone development.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003779 | actin binding | IEA | -- |
Phenotypes for PLS3 Gene
- MGI mutant phenotypes for PLS3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PLS3:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability in esophageal squamous lineage
- Increased shRNA abundance (Z-score > 2)
- Decreased POU5F1-GFP protein expression
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased cell migration
- Increased cilium length after serum starvation
- Increased cilium length
Animal Models for PLS3 Gene
- MGI Knock Outs for PLS3:
-
- Pls3 tm1a(EUCOMM)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for PLS3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
- Search ViGene Biosciences for PLS3
CRISPR Products
-
OriGene CRISPR knockouts for PLS3
-
Santa Cruz Biotechnology (SCBT) CRISPR for PLS3
- GenScript: Design CRISPR guide RNA sequences for PLS3
miRNA for PLS3 Gene
- miRTarBase miRNAs that target PLS3
-
- hsa-mir-1-3p (MIRT023553)
- hsa-mir-215-5p (MIRT024836)
- hsa-mir-192-5p (MIRT026136)
- hsa-mir-148b-5p (MIRT038184)
- hsa-mir-193b-3p (MIRT041457)
- hsa-mir-320a (MIRT044656)
- hsa-mir-125a-5p (MIRT045702)
- hsa-mir-186-5p (MIRT240846)
- hsa-mir-6507-5p (MIRT240852)
- hsa-mir-3653-3p (MIRT329645)
- hsa-mir-3658 (MIRT329646)
- hsa-mir-218-5p (MIRT439945)
miRNA Products
- Search ViGene Biosciences for PLS3
Clone Products
- OriGene clones in human for PLS3
- OriGene ORF clones in human,mouse,rat for PLS3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PLS3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for PLS3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PLS3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-13651) for PLS3
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for PLS3 Gene
Localization for PLS3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PLS3 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 3 |
| cytoskeleton | 2 |
| nucleus | 2 |
| peroxisome | 2 |
| mitochondrion | 1 |
No data available for Gene Ontology (GO) - Cellular Components for PLS3 Gene
Pathways & Interactions for PLS3 Gene
More details on SuperPathways for PLS3
No Data Available
Interacting Proteins for PLS3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0042491 | auditory receptor cell differentiation | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for PLS3 Gene
Transcripts for PLS3 Gene
mRNA/cDNA for PLS3 Gene
- (6) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (531) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for PLS3
-
Santa Cruz Biotechnology (SCBT) CRISPR for PLS3
- GenScript: Design CRISPR guide RNA sequences for PLS3
miRNA Products
- Search ViGene Biosciences for PLS3
Clone Products
- OriGene clones in human for PLS3
- OriGene ORF clones in human,mouse,rat for PLS3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PLS3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-13651) for PLS3
Expression for PLS3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Inner Cell Mass (Early Embryonic Tissues)
- Inner Cell Mass Cells Inner Cell Mass
-
Testis (Reproductive System)
- Testicular Interstitial Cells Testis Interstitium
-
Gonad (Reproductive System)
- Primordial Germ Cells Primitive Gonad
-
Peripheral Nervous System (Nervous System)
- Schwann Precursor Cells Peripheral Nerve Domain
- Brain (Nervous System)
- Neurons
-
Uterus (Reproductive System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Kidney (Urinary System)
-
Esophagus (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for PLS3 Gene
This gene is overexpressed in Artery - Aorta (x6.3) and Artery - Tibial (x5.0).
This gene is overexpressed in Amniocyte (9.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for PLS3 Gene
SOURCE GeneReport for Unigene cluster for PLS3 Gene Hs.496622
mRNA Expression by UniProt/SwissProt for PLS3 Gene
P13797-PLST_HUMAN
Tissue specificity:
Expressed in a variety of organs, including muscle, brain, uterus and esophagus.
- Elite partner
Primer Products
-
OriGene qPCR primer pairs for PLS3
-
OriGene qPCR primer pairs and template standards for PLS3
Orthologs for PLS3 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | PLS3 35 |
|
||
| PLS3 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | PLS3 35 |
|
||
| PLS3 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Pls3 35 |
|
||
| Pls3 16 |
|
||||
| Pls3 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | PLS3 35 |
|
||
| PLS3 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Pls3 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PLS3 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | PLS3 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | PLS3 35 |
|
||
| PLS3 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | PLS3 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | pls3 35 |
|
||
| Str.17623 35 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC68681 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | pls3 35 |
|
||
| pls3 36 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | Fim 37 |
|
|
|
| Fim 36 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | Y104H12BL.1 37 |
|
|
|
| Y104H12BR.1 37 |
|
|
|||
| Y73B3B.1 37 |
|
|
|||
| plst-1 36 |
|
ManyToMany | |||
| Y73B3B.1 36 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SAC6 36 |
|
OneToMany | |
| SAC6 38 |
|
|
|||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT5G48460 35 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os01g0514600 35 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4644 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8022 36 |
|
OneToMany |
- Species with no ortholog for PLS3:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for PLS3 Gene
(2) SIMAP similar genes for PLS3 Gene using alignment to 9 proteins:
Variants for PLS3 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for PLS3 Gene
- PLST_HUMAN-P13797
- Genetic variations in PLS3 define the bone mineral density quantitative trait locus 18 (BMND18) [MIM:300910]. Variance in bone mineral density influences bone mass, contributes to size determination in the general population, and is a susceptibility factor for osteoporotic fractures.
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_035462 | A breast cancer sample | ||||
| rs869726 | -- | 115,645,752(+) | ACAAA(A/C)CAATA | intron-variant | |
| rs871773 | -- | 115,646,203(-) | ATACA(A/G)CAACT | intron-variant | |
| rs871774 | -- | 115,646,103(-) | ATATA(A/G)CTGTA | reference, synonymous-codon | |
| rs1859671 | -- | 115,643,426(+) | AACTT(A/G)GCTTT | reference, synonymous-codon |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv33994 | CNV | Gain+Loss | 17666407 |
| esv2666518 | CNV | Deletion | 23128226 |
Residual Variation Intolerance Score:
13.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.60;
13.00% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for PLS3 Gene
- Human Gene Mutation Database (HGMD)
- PLS3
Disorders for PLS3 Gene
(4) MalaCards diseases for PLS3 Gene - From: OMIM, GeneTests, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| bone mineral density qtl18, osteoporosis |
|
|
| x-linked osteoporosis with fractures |
|
|
| sezary's disease |
|
|
| osteoporosis |
|
|
Search PLS3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
PLST_HUMAN- Osteoporosis (OSTEOP) [MIM:166710]: A systemic skeletal disorder characterized by decreased bone mass and deterioration of bone microarchitecture without alteration in the composition of bone. The result is fragile bones and an increased risk of fractures, even after minimal trauma. Osteoporosis is a chronic condition of multifactorial etiology and is usually clinically silent until a fracture occurs. {ECO:0000269 PubMed:24088043}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Relevant External Links for PLS3
No data available for Genatlas for PLS3 Gene
Publications for PLS3 Gene
- Human plastin genes. Comparative gene structure, chromosome location, and differential expression in normal and neoplastic cells. (PMID: 8428952) Lin C.-S. … Leavitt J. (J. Biol. Chem. 1993) 2 3 4 67
- Expression of T-plastin, FoxP3 and other tumor-associated markers by leukemic T-cells of cutaneous T-cell lymphoma. (PMID: 18569641) Capriotti E. … Hess A.D. (Leuk. Lymphoma 2008) 3 23
- Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement. (PMID: 15741236) Giganti A. … Friederich E. (J. Cell. Sci. 2005) 3 23
- Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways. (PMID: 16115810) Ralser M. … Krobitsch S. (Hum. Mol. Genet. 2005) 3 23
- Changes in T-plastin expression with human trophoblast differentiation. (PMID: 14567899) Rao R.M. … Rao A.J. (Reprod. Biomed. Online 2003) 3 23
Products for PLS3 Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for PLS3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PLS3
- Search Origene for MassSpec and Protein Over-expression Lysates for PLS3
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- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for PLS3
- Browse OriGene Inhibitory RNA Products For PLS3
- OriGene qPCR primer pairs for PLS3
- OriGene qPCR primer pairs and template standards for PLS3
- OriGene CRISPR knockouts for PLS3
- OriGene clones in human for PLS3
- OriGene ORF clones in human,mouse,rat for PLS3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for PLS3
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- GenScript: Design CRISPR guide RNA sequences for PLS3
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- GenScript Custom Peptide Services for PLS3
- Novus Biologicals Antibodies for PLS3
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for PLS3
- Cloud-Clone Corp. Proteins for PLS3
- Browse Assay Kits at Cloud-Clone Corp.
- antibodies-online Antibodies for PLS3: See all 50
- Search antibodies-online for kits
- antibodies-online Proteins for PLS3: See all 15
- Search antibodies-online for peptides
- GeneTex PLS3 antibody for PLS3
- Search GeneTex for Proteins for PLS3
- ViGene Biosciences adenoviral particle packaged cDNA for PLS3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PLS3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PLS3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PLS3 gene
- Search ViGene Biosciences for PLS3
- Search ViGene Biosciences for PLS3
- Santa Cruz Biotechnology (SCBT) Antibodies for PLS3
- Search Santa Cruz Biotechnology (SCBT) for PLS3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PLS3
Sources for PLS3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon