Aliases for PLS1 Gene
External Ids for PLS1 Gene
Previous GeneCards Identifiers for PLS1 Gene
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010]
GeneCards Summary for PLS1 Gene
PLS1 (Plastin 1) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include calcium ion binding and actin filament binding. An important paralog of this gene is LCP1.
UniProtKB/Swiss-Prot for PLS1 Gene
Actin-bundling protein in the absence of calcium.