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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PLIN3 Gene

protein-coding   GIFtS: 62
GCID: GC19M004839

Perilipin 3

(Previous name: mannose-6-phosphate receptor binding protein 1)
(Previous symbol: M6PRBP1)
Pneumococci & Pneumococcal Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Perilipin 31 2     47-KD1
M6PRBP11 2 3 5     Cargo Selection Protein (Mannose 6 Phosphate Receptor Binding Protein)1
Placental Protein 171 2 3     Mannose-6-Phosphate Receptor Binding Protein 11
TIP472 3 5     MPR-BINDING PROTEIN1
Cargo Selection Protein TIP472 3     perilipin-32
Mannose-6-Phosphate Receptor-Binding Protein 12 3     Tail-Interacting Protein, 47 KD2
47 KDa MPR-Binding Protein2 3     47 KDa Mannose 6-Phosphate Receptor-Binding Protein3
PP172 3     

External Ids:    HGNC: 168931   Entrez Gene: 102262   Ensembl: ENSG000001053557   OMIM: 6027025   UniProtKB: O606643   

Export aliases for PLIN3 gene to outside databases

Previous GC identifers: GC19M004790 GC19M004600


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PLIN3 Gene:
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the
Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent
and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to
the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to
increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms
have been found for this gene.(provided by RefSeq, Aug 2009)

GeneCards Summary for PLIN3 Gene: 
PLIN3 (perilipin 3) is a protein-coding gene. Diseases associated with PLIN3 include sebaceous adenoma, and vaccinia, and among its related super-pathways are Clathrin-dependent protein traffic. GO annotations related to this gene include protein binding. An important paralog of this gene is PLIN2.

UniProtKB/Swiss-Prot: PLIN3_HUMAN, O60664
Function: Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi
network

Gene Wiki entry for PLIN3 (M6PRBP1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011255.14  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for PLIN3
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPLIN3 promoter sequence
   Search SABiosciences Chromatin IP Primers for PLIN3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PLIN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

PLIN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PLIN3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M004839:  view genomic region     (about GC identifiers)

Start:
4,838,346 bp from pter      End:
4,867,780 bp from pter
Size:
29,435 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PLIN3_HUMAN, O60664 (See protein sequence)
Recommended Name: Perilipin-3  
Size: 434 amino acids; 47075 Da
Subunit: Homooligomer. Interacts with M6PR (via the cytoplasmic domain). Interacts with IGF2R (via the cytoplasmic
domain). Isoform 2 may exist as a homodimer (known as PP17C)
Subcellular location: Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side (Potential).
Lipid droplet (Potential). Note=Membrane associated on endosomes. Detected in the envelope and the core of lipid
bodies and in lipid sails
Secondary accessions: A8K4Y9 K7EQF4 Q53G77 Q9BS03 Q9UBD7 Q9UP92
Alternative splicing: 4 isoforms:  O60664-1   O60664-2   O60664-3   O60664-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PLIN3: NX_O60664

Explore proteomics data for PLIN3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O60664

  • PLIN3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PLIN3 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001157661.1  NP_001157666.1  NP_005808.3  

    ENSEMBL proteins: 
     ENSP00000221957   ENSP00000467803   ENSP00000468476   ENSP00000465596   ENSP00000465975  
     ENSP00000468096   ENSP00000465117  

    Human Recombinant Protein Products for PLIN3: 
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    Cloud-Clone Corp. Proteins for PLIN3 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005768endosome TAS9590177
    GO:0005794Golgi apparatus TAS9590177
    GO:0005811lipid particle IDA14741744
    GO:0010008endosome membrane IEA--

    PLIN3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PLIN: Perilipins

    1 InterPro protein domain:
     IPR004279 Perilipin

    Graphical View of Domain Structure for InterPro Entry O60664

    ProtoNet protein and cluster: O60664

    1 Blocks protein domain: IPB004279 Perilipin

    UniProtKB/Swiss-Prot: PLIN3_HUMAN, O60664
    Similarity: Belongs to the perilipin family


    PLIN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PLIN3_HUMAN, O60664
    Function: Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi
    network

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19490898
         
    PLIN3 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for PLIN3:
     Decreased viability  Increased cell number in G2M,   Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PLIN3 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for PLIN3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Clathrin-dependent protein traffic
    Transport Clathrin-coated vesicle cycle0.66
    2Cholesterol and Sphingolipids transport / Distribution to the intracellular membrane compartments (normal and CF)
    Cholesterol and Sphingolipids transport / Distribution to the intracellular membrane compartments (normal and CF)

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 GeneGo (Thomson Reuters) Pathways for PLIN3
        Transport Clathrin-coated vesicle cycle
    Cholesterol and Sphingolipids transport / Distribution to the intracellular membrane compartments (normal and CF)



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PLIN3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/14 Interacting proteins for PLIN3 (O606641, 2, 3 ENSP000002219574) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD2Q157962, 3MINT-61599 I2D: score=3 
    RHOBTB3O949551, 3, ENSP000003693184EBI-725795,EBI-2367123 I2D: score=1 STRING: ENSP00000369318
    PRAF2O608312, 3, ENSP000003655704MINT-58203 I2D: score=1 STRING: ENSP00000365570
    RAB9AP511513, ENSP000004201274I2D: score=4 STRING: ENSP00000420127
    M6PRP206453, ENSP000000004124I2D: score=3 STRING: ENSP00000000412
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016192vesicle-mediated transport TAS9590177

    PLIN3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PLIN3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PLIN3

    1 HMDB Compound for PLIN3    About this table
    CompoundSynonyms CAS #PubMed Ids
    Mannose 6-phosphateD-Mannose 6-phosphate (see all 10)3672-15-9--

    2 DrugBank Compounds for PLIN3    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Idursulfase-- 50936-59-9target--17139284 18201153 17016423 19707363 18038146
    Galsulfase-- 552858-79-4target--18709516 17016423

    4 Novoseek inferred chemical compound relationships for PLIN3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mannose 6-phosphate 84.1 20 12535272 (5), 10829017 (3), 16473602 (2), 19451273 (1) (see all 11)
    triacylglycerol 54.6 1 19451273 (1)
    lipid 53 44 19286631 (4), 15545278 (4), 19451273 (3), 12077142 (3) (see all 15)
    oleic acid 25.9 1 19286631 (1)

    Search CenterWatch for drugs/clinical trials and news about PLIN3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PLIN3 gene (3 alternative transcripts): 
    NM_001164189.1  NM_001164194.1  NM_005817.4  

    Unigene Cluster for PLIN3:

    Perilipin 3
    Hs.140452  [show with all ESTs]
    Unigene Representative Sequence: NM_005817
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000221957(uc002mbj.2 uc002mbk.2 uc002mbl.3) ENST00000592528
    ENST00000589163 ENST00000585479 ENST00000589034 ENST00000589494 ENST00000587462


    miRNA
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    Additional mRNA sequence: 

    AF051314.1 AF051315.1 AF055574.1 AF057140.1 AK122671.1 AK223054.1 AK225045.1 AK225400.1 
    AK226088.1 AK291104.1 AK312740.1 BC001590.2 BC005818.2 BC007566.1 BC019278.1 BT007235.1 

    23 DOTS entries:

    DT.87016130  DT.91998370  DT.100814644  DT.121448014  DT.100814633  DT.100814634  DT.101985172  DT.100814628 
    DT.121448013  DT.100814625  DT.121448029  DT.100814642  DT.121448015  DT.95167273  DT.95261621  DT.95337660 
    DT.121447988  DT.92471308  DT.95347206  DT.100759476  DT.100814624  DT.100814632  DT.40131602 

    12 AceView cDNA sequences:

    CR607156 NM_005817 AK122671 AF057140 BC005818 AF051315 AF051314 BC019278 
    AF055574 BC007566 BC001590 BT007235 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for PLIN3 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c · 9d
    SP1:                    -     -     -                                                                                                   
    SP2:                    -     -     -                                                                                                   
    SP3:                    -     -     -                                   -                                                               
    SP4:                                                                                                  -                                 
    SP5:                    -           -                                                                                                   


    ECgene alternative splicing isoforms for PLIN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PLIN3 expression in normal human tissues (normalized intensities)      PLIN3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTAGCAGGTG
    PLIN3 Expression
    About this image


    PLIN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/30 selected tissues (see all 30) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Myelinating Oligodendrocyte Cells Forebrain White Matter
             Cerebral Cortex
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Tonsil (Hematopoietic System)    fully expand to see all 3 entries
             tonsil ; squamous epithelial cells   

    See PLIN3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PLIN3

    SOURCE GeneReport for Unigene cluster: Hs.140452
        SABiosciences Custom PCR Arrays for PLIN3
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLIN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for PLIN3 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Plin31 , 5 perilipin 31, 5 77.14(n)1
    75.75(a)1
      17 (29.25 cM)5
    669051  NM_025836.31  NP_080112.11 
     562789625 
    chicken
    (Gallus gallus)
    Aves LOC1008574331 perilipin-3-like 67.71(n)
    55.53(a)
      100857433  XM_003642858.1  XP_003642906.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 6)
    Uncharacterized protein
    (see all 6)
    50(a)
    45(a)
    (see all 6)
    possible ortholog
    possible ortholog
    (see all 6)
    GL343757.1(54113-63414)
    5(14727739-14733053)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC537502 similar to cargo selection protein (mannose 6 phosphate more 74.61(n)    BC046724.1 
    zebrafish
    (Danio rerio)
    Actinopterygii PLIN56
    perilipin 5
    27(a)
    1 → many
    8(19775992-19805801)


    ENSEMBL Gene Tree for PLIN3 (if available)
    TreeFam Gene Tree for PLIN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PLIN3 gene
    PLIN22  PLIN52  PLIN42  PLIN12  
    3 SIMAP similar genes for PLIN3 using alignment to 5 protein entries:     PLIN3_HUMAN (see all proteins):
    PLIN2    ADFP    PLIN5

    PLIN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/953 SNPs in PLIN3 are shown (see all 953)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs606851061,2
    C--4616226(+) TTTTT-/T/TTTT
            
    CTTTT
    3 -- int11NA 2
    rs1477122601,2
    C--4616699(+) TTTTT-/GTTTTA 3 -- int10--------
    rs106506681,2
    C,F--4618225(+) AAAAA-/A/AG/G
            
    TGCAA
    3 -- int12NA CSA 4
    rs355077191,2
    C--4618227(+) AAAAT-/AG/G  
            
    GCAAG
    3 -- int10--------
    rs1381559331,2
    C--4628076(+) TCGCC-/CTGTCGC 3 -- int10--------
    rs1878128441,2
    --4762348(+) GGCTGG/TAGTGC 3 -- int1 ds50010--------
    rs1470585241,2
    --4762361(+) TAGTGC/TGATCT 3 -- int1 ds50010--------
    rs1383366461,2
    --4762400(+) CTCAAA/GTGACC 3 -- int1 ds50010--------
    rs1128203861,2
    C--4762470(+) TTGCTG/ATGTTG 3 -- int1 ds50011Minor allele frequency- A:0.50CSA 2
    rs1921988231,2
    --4762521(+) CACCTC/TGGCCT 3 -- int1 ds50010--------

    HapMap Linkage Disequilibrium report for PLIN3 (4838346 - 4867780 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for PLIN3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2664700CNV Deletion23128226
    nsv910861CNV Loss21882294
    nsv522005CNV Loss19592680
    nsv910862CNV Loss21882294
    nsv470117CNV Loss18288195
    nsv910859CNV Loss21882294
    nsv910860CNV Loss21882294
    nsv528462CNV Loss19592680
    nsv516323CNV Loss19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602702    OMIM disorders: --

    9 diseases for PLIN3:    About MalaCards
    sebaceous adenoma    vaccinia    measles    cervicitis
    obesity    colorectal cancer    insulin resistance    cervical cancer
    adenoma

    1 disease from the University of Copenhagen DISEASES database for PLIN3:
    Sebaceous adenoma

    PLIN3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

    5 Novoseek inferred disease relationships for PLIN3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cervical carcinoma 56.8 6 19331227 (2), 11299819 (2), 9874244 (1), 10697545 (1)
    colorectal cancer 0 1 16166432 (1)
    tumors 0 3 19331227 (1), 20081801 (1)
    obesity 0 1 17353663 (1)
    immunodeficiency 0 1 12768012 (1)

    Genetic Association Database (GAD): PLIN3

    Export disorders for PLIN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PLIN3 gene, integrated from 9 sources (see all 98):
    (articles sorted by number of sources associating them with PLIN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking. (PubMed id 9590177)1, 2, 3, 9 Diaz E. and Pfeffer S.R. (1998)
    2. Purification and characterization of two new soluble placental tissue proteins (PP13 and PP17). (PubMed id 6856484)1, 2, 3 Bohn H.... Winckler W. (1983)
    3. Cloning and sequence analysis of cDNAs encoding human placental tissue protein 17 (PP17) variants. (PubMed id 9874244)1, 2, 9 Than N.G.... Bohn H. (1998)
    4. Spatial integration of TIP47 and adipophilin in macrophage lipid bodies. (PubMed id 15545278)1, 2, 9 Robenek H.... Troyer D. (2005)
    5. Cloning and sequencing of human oncodevelopmental soluble placental tissue protein 17 (PP17): homology with adipophilin and the mouse adipose differentiation-related protein. (PubMed id 10393528)1, 2, 9 Than N.G.... Bohn H. (1999)
    6. Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins. (PubMed id 19638644)1, 3 Kimmel A.R....Londos C. (2010)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport. (PubMed id 12535272)1, 9 Sincock P.M....Pfeffer S.R. (2003)
    10. TIP47 functions in the biogenesis of lipid droplets. (PubMed id 19451273)1, 9 Bulankina A.V....HAPning S. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10226 HGNC: 16893 AceView: M6PRBP1 Ensembl:ENSG00000105355 euGenes: HUgn10226
    ECgene: PLIN3 H-InvDB: PLIN3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PLIN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PLIN3 gene:
    Search GeneIP for patents involving PLIN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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