PLIN2 Gene
protein-coding GIFtS: 61
GCID: GC09M019077
|
|
perilipin 2(Previous name: adipose differentiation-related protein )
(Previous symbol: ADFP)
| |
Aliases
for PLIN2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Perilipin 21 2 | | Adipophilin3 | | Adipose Differentiation-Related Protein1 2 3 | | Perilipin-21 | | ADFP1 2 3 | | Adipophilin3 | | ADRP1 2 3 | | |
Export aliases for PLIN2 gene to outside databasesPrevious GC identifer: GC09M019106 |
Summaries
for PLIN2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PLIN2:
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storagedroplets. This protein is associated with the lipid globule surface membrane material, and maybe involved indevelopment and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, butis found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues,such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic livercirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.Alternatively spliced transcript variants have been found for this gene. (provided by RefSeq, Mar 2011)
UniProtKB/Swiss-Prot: PLIN2_HUMAN, Q99541Function: May be involved in development and maintenance of adipose tissue (By similarity)
Gene Wiki entry for PLIN2 (Adipose differentiation-related protein)
|
Genomic Views
for PLIN2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008413.18
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for PLIN2
Other transcription factors
Search SABiosciences Chromatin IP Primers for PLIN2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PLIN2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p22.1 Ensembl cytogenetic band: 9p22.1 HGNC cytogenetic band: 9p22.1PLIN2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M019077: view genomic region
(about GC identifiers)
Start:
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19,108,373 bp from pter |
End:
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19,149,288 bp from pter |
Size:
|
40,916 bases |
Orientation:
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minus strand |
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Proteins
for PLIN2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PLIN2_HUMAN, Q99541 (See
protein sequence)Recommended Name: Perilipin-2 Size: 437 amino acids; 48075 Da
Subcellular location: Membrane; Peripheral membrane protein
Secondary accessions: Q9BSC3Explore the universe of human proteins at neXtProt for PLIN2: NX_Q99541
Post-translational modifications:
Acylated; primarily with C14, C16 and C18 fatty acids1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99541
PLIN2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001113.2
ENSEMBL proteins: ENSP00000276914 ENSP00000403421 ENSP00000369832 ENSP00000369831 ENSP00000415270 Reactome Protein details: Q99541
Human Recombinant Protein Products for PLIN2:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
PLIN2 for ontologies About GeneDecksing
PLIN2 Antibody Products:
Assay Products for PLIN2: |
Protein
Domains /
Families
for PLIN2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PLIN2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q99541ProtoNet protein and cluster: Q99541 1 Blocks protein family: IPB004279 Perilipin
UniProtKB/Swiss-Prot: PLIN2_HUMAN, Q99541Similarity: Belongs to the perilipin family |
Function
for PLIN2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: PLIN2_HUMAN, Q99541Function: May be involved in development and maintenance of adipose tissue (By similarity) Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
PLIN2 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for PLIN2:
8 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Plin2):
PLIN2 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Plin2tm1Itl for PLIN2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PLIN2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PLIN2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PLIN2 (NM_001122) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PLIN2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLIN2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLIN2 |
|
Pathways & Interactions
for PLIN2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | | | 2 | Metabolism | | | 3 | Expression of PLIN2 | | | 4 | Adipogenesis | | | 5 | HIF-1-alpha transcription factor network | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for PLIN2
5/6 
Reactome Pathways for PLIN2 (see all 6)
PLIN2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PLIN2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/16 Interacting proteins for PLIN2 (Q995413 ENSP000002769144) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
PLIN2 for ontologies About GeneDecksing
|
Drugs & Compounds
for PLIN2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PLIN2 for compounds About GeneDecksing
 Browse Tocris compounds for PLIN2
10/20 Novoseek chemical compound relationships for PLIN2 gene (see all 20) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lipid |
72.5 |
240 |
9392423 (8), 14707038 (6), 17872589 (6), 12804567 (5) (see all 85) |
| triacylglycerol |
63.2 |
15 |
16230742 (4), 19571381 (2), 17872589 (2), 16115879 (1) |
| oleic acid |
58.6 |
14 |
16230742 (2), 16115879 (2), 19571381 (2), 12210744 (1) (see all 6) |
| acyl-coa |
52.7 |
1 |
12893739 (1) |
| ciglitazone |
49.5 |
2 |
12914779 (1), 11420178 (1) |
| troglitazone |
47.7 |
4 |
16403437 (2), 14671211 (1) |
| fatty acid |
47.2 |
24 |
14671211 (2), 16260216 (2), 16115879 (2), 16391323 (2) (see all 14) |
| rosiglitazone |
46.9 |
4 |
19602560 (2), 15381068 (1), 12914779 (1) |
| mannose 6-phosphate |
41 |
1 |
17872589 (1) |
| sterol |
36.1 |
4 |
10954705 (1), 17671740 (1), 18192234 (1) |
Search CenterWatch for drugs/clinical trials and news about PLIN2
|
Transcripts
for PLIN2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PLIN2 gene: NM_001122.3 Unigene Cluster for PLIN2: Perilipin 2 Hs.3416 [show with all ESTs]Unigene Representative Sequence: NR_0380649 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000464326 ENST00000276914(uc003zno.3 uc011lna.2 uc011lnb.2)
ENST00000434144 ENST00000380465 ENST00000380464 ENST00000475923 ENST00000472715
ENST00000494753(uc003znp.1) ENST00000411567
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PLIN2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PLIN2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PLIN2 (NM_001122) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PLIN2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLIN2 |
Additional cDNA sequence: AF443203.1 AK022061.1 AK094196.1 AK296125.1 AK297920.1 AK312983.1 BC005127.2 CR536541.1 NR_038064.1 X97324.1 XR_113197.1 XR_171769.1 24/33 DOTS entries (see all 33): DT.91762044 DT.117107 DT.121149566 DT.100667972 DT.121149913 DT.91673230 DT.91762036 DT.95257923 DT.100771091 DT.121149936 DT.100765283 DT.91653525 DT.100054457 DT.99927880 DT.121149922 DT.100667971 DT.121149708 DT.121149740 DT.95257919 DT.97806939 DT.100059474 DT.100642377 DT.95156312 DT.100667967 24/453 AceView cDNA sequences (see all 453): BQ012135 BU733076 BQ649403 W44643 BQ011734 AU121155 BQ575060 BM980821 CD365002 BU616199 BQ018760 CA439062 CN479344 BP366836 BX108578 BQ653092 AU133301 BQ064705 CR605429 CR600234 BQ013035 BQ646820 AA862384 AA610849
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for PLIN2 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | | | - | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PLIN2
|
Expression
for PLIN2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PLIN2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGCTTGCTT
About this image
See PLIN2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PLIN2
SOURCE GeneReport for Unigene cluster: Hs.3416
UniProtKB/Swiss-Prot: PLIN2_HUMAN, Q99541Tissue specificity: Milk lipid globules
SABiosciences Expression via Pathway-Focused PCR Array including PLIN2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PLIN2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PLIN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PLIN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PLIN2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLIN2 |
Orthologs
for PLIN2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for PLIN2 gene from 4/14 species (see all 14) About this table
ENSEMBL Gene Tree for PLIN2 (if available)
TreeFam Gene Tree for PLIN2 (if available) |
Paralogs
for PLIN2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PLIN2 gene
- PLIN52 PLIN42 PLIN32 PLIN12
4 SIMAP similar genes for PLIN2 using alignment to 5 protein entries: PLIN2_HUMAN (see all proteins):ADFP PLIN3 PLIN1 PLIN5
PLIN2 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for PLIN2
PGOHUM00000244274 PGOHUM00000260632 PGOHUM00000241221
|
Genomic Variants
for PLIN2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PLIN2 (19108373 - 19149288 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for PLIN2
3 CNVs: 31465 2803 52762 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PLIN2 |
|
Disorders
/ Diseases
for PLIN2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PLIN2 for disorders About GeneDecksing
OMIM gene information: 103195
OMIM disorders: --
20/35  diseases for PLIN2 (see all 35): About MalaCardsalcoholic liver cirrhosis liver cirrhosis lipid-rich carcinoma alcoholism
acrodermatitis enteropathica enteropathica acrodermatitis renal cell carcinoma
sebaceous adenocarcinoma placental choriocarcinoma night blindness fatty liver disease
retinitis pigmentosa insulin resistance liver disease choriocarcinoma
nevus protein s deficiency carcinoma kidney cancer
5 diseases from the University of Copenhagen DISEASES database for PLIN2:Retinitis pigmentosa Sebaceous carcinoma Night blindness lipid-rich carcinoma
Neutral lipid storage disease 10/12 Novoseek disease relationships for PLIN2 gene (see all 12) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| fatty liver |
44.2 |
5 |
16403437 (3), 20032580 (1), 11397807 (1) |
| atherosclerotic plaque |
39.7 |
4 |
15961705 (2), 17620659 (1) |
| metastatic renal cell carcinoma |
36.6 |
3 |
20118912 (3) |
| insulin sensitivity |
24.5 |
1 |
19602560 (1) |
| renal cancer |
18.1 |
6 |
20375178 (3), 20435833 (1) |
| obesity |
15.6 |
1 |
17353663 (1) |
| carcinoma renal cell |
14.6 |
3 |
17200350 (1), 15682440 (1) |
| atherosclerosis |
14 |
3 |
19851831 (1), 18854426 (1) |
| carcinoma |
7 |
5 |
20118912 (2), 19120764 (1), 20081801 (1) |
| tumors |
1.51 |
15 |
20375178 (2), 20118912 (2), 17284252 (1), 17545631 (1) (see all 8) |
Human Genome Epidemiology (HuGE) Navigator: PLIN2 (1 document)
Export disorders for PLIN2 gene to outside databases
|
Publications
for PLIN2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PLIN2 gene, integrated from 9 sources (see all 163):
(articles sorted by number of sources associating them with PLIN2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane. (PubMed id 9003395)1, 2, 3, 9 Heid H.W.... Keenan T.W. (1996)
- Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins. (PubMed id 19638644)1, 3 Kimmel A.R....Londos C. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Downregulation of hepatic stellate cell activation by retinol and palmitate mediated by adipose differentiation-related protein (ADR P). (PubMed id 20143336)1, 9 Lee T.F....Friedman S.L. (2010)
- PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver. (PubMed id 16489205)1, 9 Dalen K.T....Nebb H.I. (2006)
- ADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cells. (PubMed id 16230742)1, 9 Masuda Y....Takano T. (2006)
- Adipophilin distribution and colocalization with lipid droplets in skeletal muscle. (PubMed id 19169702)1, 9 Shaw C.S....Wagenmakers A.J. (2009)
- Adipophilin expression is increased in symptomatic carotid atherosclerosis: correlation with red blood cells and cholesterol crystals. (PubMed id 17446422)1, 9 Nuotio K....Lindsberg P.J. (2007)
- Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line. (PubMed id 16391323)1, 9 Tobin K.A....Duttaroy A.K. (2006)
- Adipophilin increases triglyceride storage in human m acrophages by stimulation of biosynthesis and inhibition of beta-oxidation. (PubMed id 16884492)1, 9 Larigauderie G....Rouis M. (2006)
|
External Searches for PLIN2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PLIN2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PLIN2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PLIN2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PLIN2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PLIN2 gene:
Search GeneIP for patents involving PLIN2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for PLIN2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | OriGene Antibodies for PLIN2 | | OriGene shRNA RFP for PLIN2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PLIN2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PLIN2 | | | OriGene Protein Over-expression Lysate for PLIN2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PLIN2 | | OriGene 3'-UTR Clone for PLIN2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PLIN2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PLIN2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PLIN2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PLIN2 | | OriGene Custom Protein Services for PLIN2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PLIN2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PLIN2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PLIN2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PLIN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PLIN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PLIN2 |
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| | | | Search Tocris compounds for PLIN2 |
| |  |  |  |  | | | | | | Recombinant Protein for PLIN2 |
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 | | | PLIN2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLIN2 |
|  |  |  |  | | | | ThermoFisher Antibody for PLIN2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLIN2 |
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