Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



PLEKHJ1 Gene

protein-coding   GIFtS: 47
GCID: GC19M002233

Pleckstrin Homology Domain Containing, Family J Member 1

  Search for PLEKHJ1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Pleckstrin Homology Domain Containing, Family J Member 11 2     PH Domain-Containing Family J Member 12 3
Guanine Nucleotide Releasing Protein X1 2     9530063M10Rik2
Guanine Nucleotide-Releasing Protein X2 3     Pleckstrin Homology Domain-Containing Family J Member 12
GNRPX2 3     

External Ids:    HGNC: 182111   Entrez Gene: 551112   Ensembl: ENSG000001048867   UniProtKB: Q9NW613   

Export aliases for PLEKHJ1 gene to outside databases

Previous GC identifers: GC19M002185 GC19M002186 GC19M002004


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for PLEKHJ1 Gene:
PLEKHJ1 (pleckstrin homology domain containing, family J member 1) is a protein-coding gene. GO annotations related to this gene include phospholipid binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000019.10  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PLEKHJ1 gene promoter:
         Spz1   p53   AP-1   ATF-2   MyoD   GATA-1   SREBP-1a   c-Jun   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPLEKHJ1 promoter sequence
   Search Chromatin IP Primers for PLEKHJ1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PLEKHJ1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

PLEKHJ1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PLEKHJ1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M002233:  view genomic region     (about GC identifiers)

Start:
2,230,002 bp from pter      End:
2,237,703 bp from pter
Size:
7,702 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: PKHJ1_HUMAN, Q9NW61 (See protein sequence)
Recommended Name: Pleckstrin homology domain-containing family J member 1  
Size: 149 amino acids; 17551 Da
Secondary accessions: B3KUQ9 D6W604

Explore the universe of human proteins at neXtProt for PLEKHJ1: NX_Q9NW61

Explore proteomics data for PLEKHJ1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys6
  • Modification sites at PhosphoSitePlus

  • See PLEKHJ1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060519.1  
    ENSEMBL proteins: 
     ENSP00000464955   ENSP00000468441   ENSP00000464924   ENSP00000465391   ENSP00000468257  
     ENSP00000318075  

    PLEKHJ1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for PLEKHJ1
    OriGene Protein Over-expression Lysate for PLEKHJ1
    OriGene MassSpec for PLEKHJ1
    OriGene Custom Protein Services for PLEKHJ1
    GenScript Custom Purified and Recombinant Proteins Services for PLEKHJ1
    Novus Biologicals PLEKHJ1 Protein
    Novus Biologicals PLEKHJ1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PLEKHJ1

    PLEKHJ1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for PLEKHJ1
    OriGene Custom Antibody Services for PLEKHJ1
    Novus Biologicals PLEKHJ1 Antibodies
    Search for Antibodies for PLEKHJ1 at Abcam
    Cloud-Clone Corp. Antibodies for PLEKHJ1
    ThermoFisher Antibodies for PLEKHJ1
    LSBio Antibodies in human, mouse, rat for PLEKHJ1

    PLEKHJ1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PLEKHJ1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PLEKHJ1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PLEKHJ1
    Cloud-Clone Corp. CLIAs for PLEKHJ1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    PLEKH: Pleckstrin homology (PH) domain containing

    2 InterPro protein domains:
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q9NW61

    ProtoNet protein and cluster: Q9NW61

    1 Blocks protein domain: IPB001849 Pleckstrin-like

    UniProtKB/Swiss-Prot: PKHJ1_HUMAN, Q9NW61
    Similarity: Contains 1 PH domain


    PLEKHJ1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 GenomeRNAi human phenotype for PLEKHJ1:
     Decreased circadian period len 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PLEKHJ1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PLEKHJ1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PLEKHJ1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PLEKHJ1

    miRNA
    Products:
        
    miRTarBase miRNAs that target PLEKHJ1:
    hsa-mir-625-5p (MIRT039590)

    Block miRNA regulation of human, mouse, rat PLEKHJ1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PLEKHJ1 (see all 9):
    hsa-miR-181c hsa-miR-513a-5p hsa-miR-27a hsa-miR-181a hsa-miR-181d hsa-miR-583 hsa-miR-27b hsa-miR-4262
    SwitchGear 3'UTR luciferase reporter plasmidPLEKHJ1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PLEKHJ1
    Predesigned siRNA for gene silencing in human, mouse, rat PLEKHJ1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PLEKHJ1

    Clone
    Products:
         
    OriGene clones in human, mouse for PLEKHJ1 (see all 6)
    OriGene ORF clones in mouse, rat for PLEKHJ1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PLEKHJ1 (NM_018049)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PLEKHJ1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLEKHJ1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for PLEKHJ1
    Browse ESI BIO Cell Lines and PureStem Progenitors for PLEKHJ1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLEKHJ1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    extracellular1
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PLEKHJ1
    Interactions:

        Search GeneGlobe Interaction Network for PLEKHJ1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for PLEKHJ1 (Q9NW612, 3 ENSP000003180754) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FAM109AQ8N4B12, 3, ENSP000003544614MINT-8266755 I2D: score=2 STRING: ENSP00000354461
    PPBPP027752, 3MINT-8266766 I2D: score=2 
    DNMT3BQ9UBC32, 3, ENSP000003285474MINT-8266744 I2D: score=2 STRING: ENSP00000328547
    ACVR1Q047713, ENSP000002636404I2D: score=3 STRING: ENSP00000263640
    KRT33BQ145253, ENSP000002516464I2D: score=2 STRING: ENSP00000251646
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PLEKHJ1 (PKHJ1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for PLEKHJ1 gene: 
    NM_018049.1  

    Unigene Cluster for PLEKHJ1:

    Pleckstrin homology domain containing, family J member 1
    Hs.501353  [show with all ESTs]
    Unigene Representative Sequence: AK092742
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000587394 ENST00000587962 ENST00000586608 ENST00000588450 ENST00000589097
    ENST00000591099 ENST00000589791 ENST00000588633 ENST00000588545 ENST00000585423
    ENST00000586497 ENST00000588356 ENST00000326631(uc002lvf.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PLEKHJ1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PLEKHJ1 (see all 9):
    hsa-miR-181c hsa-miR-513a-5p hsa-miR-27a hsa-miR-181a hsa-miR-181d hsa-miR-583 hsa-miR-27b hsa-miR-4262
    SwitchGear 3'UTR luciferase reporter plasmidPLEKHJ1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PLEKHJ1
    Predesigned siRNA for gene silencing in human, mouse, rat PLEKHJ1
    Clone
    Products:
         
    OriGene clones in human, mouse for PLEKHJ1 (see all 6)
    OriGene ORF clones in mouse, rat for PLEKHJ1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PLEKHJ1 (NM_018049)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PLEKHJ1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLEKHJ1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PLEKHJ1
    OriGene qSTAR qPCR primer pairs in human, mouse for PLEKHJ1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PLEKHJ1
      QuantiTect SYBR Green Assays in human, mouse, rat PLEKHJ1
      QuantiFast Probe-based Assays in human, mouse, rat PLEKHJ1

    Additional mRNA sequence: 

    AK001159.1 AK092742.1 AK097723.1 AK098725.1 BC003084.2 BC008966.2 CR457253.1 

    20 DOTS entries:

    DT.448054  DT.101964236  DT.100807784  DT.403963  DT.121414422  DT.121414213  DT.92433550  DT.97780970 
    DT.100749671  DT.100807776  DT.100028718  DT.121414513  DT.100028713  DT.100807775  DT.100807777  DT.121414705 
    DT.121414842  DT.121414847  DT.91844266  DT.75138156 

    Selected AceView cDNA sequences (see all 241):

    BE408098 BM763916 AI804203 BE616973 CA442067 BX341464 BM674615 BC003084 
    BI909856 CA503043 CB242308 AK001159 BM128038 CB141085 AX747701 BQ070977 
    BC008966 AA304871 BM821176 BI091243 CB113220 BQ636992 BM714525 BQ892843 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for PLEKHJ1 (see all 9)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8
    SP1:        -     -     -                 -     -     -                                 
    SP2:                                      -     -     -                                 
    SP3:                                      -     -     -                 -     -         
    SP4:                                      -     -     -                                 
    SP5:                                      -     -     -     -                           


    ECgene alternative splicing isoforms for PLEKHJ1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    PLEKHJ1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCCCCTGC
    PLEKHJ1 Expression
    About this image

    PLEKHJ1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PLEKHJ1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.501353

    UniProtKB/Swiss-Prot: PKHJ1_HUMAN, Q9NW61
    Tissue specificity: Expressed in testis and liver

        Custom PCR Arrays for PLEKHJ1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for PLEKHJ1
    OriGene qSTAR qPCR primer pairs in human, mouse for PLEKHJ1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PLEKHJ1
    QuantiTect SYBR Green Assays in human, mouse, rat PLEKHJ1
    QuantiFast Probe-based Assays in human, mouse, rat PLEKHJ1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLEKHJ1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for PLEKHJ1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Plekhj11 , 5 pleckstrin homology domain containing, family J member more1, 5 86.17(n)1
    87.76(a)1
      10 (39.72 cM)5
    786701  NM_023900.21  NP_076389.21 
     807961005 
    chicken
    (Gallus gallus)
    Aves PLEKHJ11 pleckstrin homology domain containing, family J member more 79(n)
    82.88(a)
      428324  NM_001031503.1  NP_001026674.1 
    lizard
    (Anolis carolinensis)
    Reptilia PLEKHJ16
    pleckstrin homology domain containing, family J me...
    80(a)
    1 ↔ 1
    AAWZ02038099(807-1183)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia plekhj11 pleckstrin homology domain containing, family J member more 71.53(n)
    77.78(a)
      394773  NM_203835.1  NP_989166.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005379511 pleckstrin homology domain-containing family J member more 68.49(n)
    69.18(a)
      100537951  XM_003197976.2  XP_003198024.1 


    ENSEMBL Gene Tree for PLEKHJ1 (if available)
    TreeFam Gene Tree for PLEKHJ1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for PLEKHJ1 gene
    1 SIMAP similar gene for PLEKHJ1 using alignment to 5 protein entries:     PKHJ1_HUMAN (see all proteins):
    FAM109A

    PLEKHJ1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for PLEKHJ1 (see all 22)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs38332831,2
    C--2233193(-) GGGCCA/-GGGTG 1 -- ut313Minor allele frequency- -:0.17NA CSA 6
    rs721014601,2
    C--2233329(+) CGGGG-/CAGGGGGGCCATGCC
    ACCAGCCTGGGGGCTCAC
    CAGGC
    1 -- cds10--------
    rs1819206241,2
    --2233386(+) AACTCA/CGGCAG 1 -- ut310--------
    rs802241421,2
    C,F--2233410(+) AGGCGC/TATATC 1 -- ut311Minor allele frequency- T:0.13EA 120
    rs1148003351,2
    C,F--2233432(+) AGCACG/ATGGCA 1 -- ut311Minor allele frequency- A:0.03WA 118
    rs775855721,2
    C,F--2233482(+) GGAGCG/ACAGCT 1 -- ut313Minor allele frequency- A:0.04WA NA EA 358
    rs748073051,2
    C--2234086(+) GGGTCA/TAATGC 1 -- int10--------
    rs1907888381,2
    C--2234093(+) ATGCCC/TGCTCT 1 -- int10--------
    rs2019976891,2
    C--2234134(+) CCACCA/GCCGCC 1 -- int10--------
    rs1124406281,2
    ----2234146(+) GGCCCG/CACCTG 1 -- int11Minor allele frequency- C:0.50NA 2

    HapMap Linkage Disequilibrium report for PLEKHJ1 (2230002 - 2237703 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for PLEKHJ1 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2389CNV Insertion18451855
    dgv3631n71CNV Loss21882294
    dgv3630n71CNV Loss21882294
    dgv3614n71CNV Loss21882294
    dgv3629n71CNV Loss21882294
    nsv910499CNV Loss21882294
    dgv3632n71CNV Loss21882294
    dgv3626n71CNV Loss21882294
    dgv3622n71CNV Loss21882294
    dgv3633n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PLEKHJ1
    DNA2.0 Custom Variant and Variant Library Synthesis for PLEKHJ1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for PLEKHJ1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with PLEKHJ1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. An expressed GNRP-like gene shares a bi-directional promoter with SF3A2 (SAP62) immediately upstream of AMH. (PubMed id 11602354)1, 2, 3 Dresser D.W.... Guerrier D. (Gene 2001)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    7. Expanding the substantial interactome of NEMO using protein microarrays. (PubMed id 20098747)1 Fenner B.J....Prehn J.H. (PLoS ONE 2010)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    9. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M....Figeys D. (Mol. Syst. Biol. 2007)
    10. High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)1 Barrios-Rodiles M....Wrana J.L. (Science 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 55111 HGNC: 18211 AceView: PLEKHJ1 Ensembl:ENSG00000104886 euGenes: HUgn55111
    ECgene: PLEKHJ1 H-InvDB: PLEKHJ1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for PLEKHJ1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for PLEKHJ1 gene:
    Search GeneIP for patents involving PLEKHJ1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for PLEKHJ1   OriGene RNAi products in human, mouse, rat for PLEKHJ1  
     OriGene qPCR primer pairs and template standards for PLEKHJ1   OriGene Protein Over-expression Lysate for PLEKHJ1  
     OriGene MassSpec something-or-other for PLEKHJ1   OriGene clones in human, mouse for PLEKHJ1  
     OriGene qSTAR qPCR primer pairs in human, mouse for PLEKHJ1   OriGene Purified Protein for PLEKHJ1  
     OriGene ORF clones in mouse, rat for PLEKHJ1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PLEKHJ1   OriGene Custom Protein Services for PLEKHJ1  

     
     
     Block miRNA regulation of human, mouse, rat PLEKHJ1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PLEKHJ1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PLEKHJ1 Predesigned siRNA for gene silencing in human, mouse, rat PLEKHJ1
     QuantiFast Probe-based Assays in human, mouse, rat PLEKHJ1 QuantiTect SYBR Green Assays in human, mouse, rat PLEKHJ1
     Custom PCR Arrays for PLEKHJ1 Search Chromatin IP Primers for PLEKHJ1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PLEKHJ1  Search GeneGlobe Interaction Network for PLEKHJ1
     Regulatory tfbs in PLEKHJ1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for PLEKHJ1 GenScript cDNA clones with any tag delivered in your preferred vector for PLEKHJ1
     GenScript Custom Assay Services for PLEKHJ1 GenScript Custom overexpressing Cell Line Services for PLEKHJ1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for PLEKHJ1 (PKHJ1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     PLEKHJ1 antibodies
     PLEKHJ1 proteins
     PLEKHJ1 lysates
     Search for Antibodies for PLEKHJ1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for PLEKHJ1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for PLEKHJ1
     Antibodies for PLEKHJ1
     ELISAs for PLEKHJ1
     CLIAs for PLEKHJ1



     Browse ESI BIO Cell Lines and PureStem Progenitors for PLEKHJ1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLEKHJ1
     SwitchGear 3'UTR luciferase reporter plasmids for PLEKHJ1
     SwitchGear Promoter luciferase reporter plasmids for PLEKHJ1
     ThermoFisher Antibodies for PLEKHJ1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLEKHJ1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PLEKHJ1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PLEKHJ1
     LSBio Antibodies in human, mouse, rat for PLEKHJ1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      PLEKHJ1 gene at Home site.
    Version: 3.12.162 20 Aug 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4