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PLEKHG1 Gene

protein-coding   GIFtS: 50
GCID: GC06P150920

Pleckstrin Homology Domain Containing, Family G (With RhoGef...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain)
Member 11 2
ARHGEF412
Pleckstrin Homology Domain-Containing Family G Member 12
KIAA12093

External Ids:    HGNC: 208841   Entrez Gene: 574802   Ensembl: ENSG000001202787   UniProtKB: Q9ULL13   

Export aliases for PLEKHG1 gene to outside databases

Previous GC identifers: GC06P150997 GC06P151073 GC06P151013 GC06P148515


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PLEKHG1 Gene:
PLEKHG1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 1) is a protein-coding gene. GO annotations related to this gene include phospholipid binding and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGEF6.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PLEKHG1 gene promoter:
         MEF-2A   AML1a   p53   MEF-2   aMEF-2   E47   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): PLEKHG1 promoter sequence
   Search Chromatin IP Primers for PLEKHG1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PLEKHG1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25.1   Ensembl cytogenetic band:  6q25.1   HGNC cytogenetic band: 6q25.1

PLEKHG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PLEKHG1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P150920:  view genomic region     (about GC identifiers)

Start:
150,920,999 bp from pter      End:
151,164,799 bp from pter
Size:
243,801 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PKHG1_HUMAN, Q9ULL1 (See protein sequence)
Recommended Name: Pleckstrin homology domain-containing family G member 1  
Size: 1385 amino acids; 155439 Da
Secondary accessions: Q5T1F2

Explore the universe of human proteins at neXtProt for PLEKHG1: NX_Q9ULL1

Explore proteomics data for PLEKHG1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PLEKHG1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001025055.1  
    ENSEMBL proteins: 
     ENSP00000356295   ENSP00000351318   ENSP00000433107   ENSP00000356297  

    PLEKHG1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for PLEKHG1

     
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    antibodies-online antibodies for PLEKHG1 (7 products) 

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    Cloud-Clone Corp. ELISAs for PLEKHG1
    Cloud-Clone Corp. CLIAs for PLEKHG1
    Search eBioscience for ELISAs for PLEKHG1 
    antibodies-online kits for PLEKHG1 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PLEKH: Pleckstrin homology (PH) domain containing
    ARHGEF: Rho guanine nucleotide exchange factors

    3 InterPro protein domains:
     IPR000219 DH-domain
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q9ULL1

    ProtoNet protein and cluster: Q9ULL1

    2 Blocks protein domains:
    IPB000219 DH domain
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: PKHG1_HUMAN, Q9ULL1
    Similarity: Contains 1 DH (DBL-homology) domain
    Similarity: Contains 1 PH domain


    Find genes that share domains with PLEKHG1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005089Rho guanyl-nucleotide exchange factor activity IEA--
         
    Find genes that share ontologies with PLEKHG1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for PLEKHG1:
     Decreased viability with pacli  Increased gamma-H2AX phosphory 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Plekhg1):
     hematopoietic system  immune system 

    Find genes that share phenotypes with PLEKHG1           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for PLEKHG1

    miRNA
    Products:
        
    miRTarBase miRNAs that target PLEKHG1:
    hsa-mir-335-5p (MIRT016820)

    Block miRNA regulation of human, mouse, rat PLEKHG1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PLEKHG1 (see all 27):
    hsa-miR-676 hsa-miR-4307 hsa-miR-520d-5p hsa-miR-1224-3p hsa-miR-106a hsa-miR-16-1* hsa-miR-218 hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidPLEKHG1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PLEKHG1
    Predesigned siRNA for gene silencing in human, mouse, rat PLEKHG1

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for PLEKHG1 (see all 8)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PLEKHG1 (NM_001029884)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLEKHG1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLEKHG1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PLEKHG1
    Interactions:

        Search GeneGlobe Interaction Network for PLEKHG1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for PLEKHG1 (ENSP000003513184) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PXNENSP000002283074STRING: ENSP00000228307
    TGFB1I1ENSP000003783324STRING: ENSP00000378332
    ARHGAP12ENSP000003458084STRING: ENSP00000345808
    --ENSP000002638454STRING: ENSP00000263845
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    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035023regulation of Rho protein signal transduction ----

    Find genes that share ontologies with PLEKHG1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PLEKHG1 (PKHG1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PLEKHG1 gene: 
    NM_001029884.1  

    Unigene Cluster for PLEKHG1:

    Pleckstrin homology domain containing, family G (with RhoGef domain) member 1
    Hs.189781  [show with all ESTs]
    Unigene Representative Sequence: NM_001029884
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367326 ENST00000358517(uc011eem.1 uc003qnz.2) ENST00000475490
    ENST00000367328(uc011eel.1 uc003qny.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PLEKHG1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PLEKHG1 (see all 27):
    hsa-miR-676 hsa-miR-4307 hsa-miR-520d-5p hsa-miR-1224-3p hsa-miR-106a hsa-miR-16-1* hsa-miR-218 hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidPLEKHG1 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Predesigned siRNA for gene silencing in human, mouse, rat PLEKHG1
    Clone
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    OriGene ORF clones in mouse, rat for PLEKHG1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PLEKHG1 (NM_001029884)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PLEKHG1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLEKHG1
    Primer
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    Browse OriGene qPCR
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PLEKHG1
      QuantiTect SYBR Green Assays in human, mouse, rat PLEKHG1
      QuantiFast Probe-based Assays in human, mouse, rat PLEKHG1

    Additional mRNA sequence: 

    AB033035.1 AJ420468.1 AK056300.1 AK293288.1 AK294798.1 AK307631.1 BC089428.1 BC140864.1 
    BC151134.1 

    3 DOTS entries:

    DT.208151  DT.75163224  DT.97762352 

    Selected AceView cDNA sequences (see all 88):

    AI003646 AA361039 CR606130 AA404653 BM747026 AB033035 AI148832 CA438343 
    AA719072 BU607617 AA719089 R02147 AA829505 AA737629 N70181 AL545703 
    BQ004504 AW628704 BQ081981 BX956594 AI400610 AA743619 BU752631 AI816833 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PLEKHG1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTGTATTTT
    PLEKHG1 Expression
    About this image


    PLEKHG1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 15 entries
             Thalamus
             Septum   
     
     Blood (Cardiovascular System)    fully expand to see all 4 entries
             Mature B-Cells Peripheral Blood
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus
     
     Inner Cell Mass (Early Embryonic Tissues)
             Blimp1- mVenus and stella-ECFP genetically modified stem cells
    PLEKHG1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PLEKHG1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.189781
        Custom PCR Arrays for PLEKHG1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLEKHG1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PLEKHG1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Plekhg11 , 5 pleckstrin homology domain containing, family G (with more1, 5 80.77(n)1
    79.58(a)1
      10 (2.06 cM)5
    2137831  NM_001159942.11  NP_001153414.11 
     37403645 
    chicken
    (Gallus gallus)
    Aves PLEKHG11 pleckstrin homology domain containing, family G (with more 68.39(n)
    68.15(a)
      421632  XM_419671.4  XP_419671.3 
    lizard
    (Anolis carolinensis)
    Reptilia PLEKHG16
    pleckstrin homology domain containing, family G (w...
    63(a)
    1 ↔ 1
    GL343259.1(638809-780461)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.40072 Transcribed sequence with weak similarity to protein more 77.67(n)    137718971 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018868101 pleckstrin homology domain-containing family G member more 70.65(n)
    77.72(a)
      101886810  XM_005174089.1  XP_005174146.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta GEFmeso6
    Guanine nucleotide exchange factor in mesoderm
    17(a)
    1 → many
    2R(14441624-14499260)
    worm
    (Caenorhabditis elegans)
    Secernentea uig-16
    Protein UIG-1, isoform c
    23(a)
    1 → many
    V(13273177-13295913) WBGene00009337


    ENSEMBL Gene Tree for PLEKHG1 (if available)
    TreeFam Gene Tree for PLEKHG1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PLEKHG1 gene
    ARHGEF62  PLEKHG22  PLEKHG32  PREX22  ENSG000002731672  ARHGEF72  TIAM12  SPATA132  
    TIAM22  ARHGEF92  ARHGEF42  PREX12  
    2 SIMAP similar genes for PLEKHG1 using alignment to 5 protein entries:     PKHG1_HUMAN (see all proteins):
    PLEKHG3    PLEKHG2

    Find genes that share paralogs with PLEKHG1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PLEKHG1 (see all 5685)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1470829881,2
    --150919177(+) AAGTTC/TGAGGC 1 -- us2k10--------
    rs1837793381,2
    --150919205(+) CGTGAA/CCCCGG 1 -- us2k10--------
    rs1434496041,2
    C--150919217(+) TCTAC-/AAAAAA 1 -- us2k10--------
    rs94787631,2
    --150919326(+) ctacaA/Gtgagc 1 -- us2k10--------
    rs1419823501,2
    --150919348(+) CCACCA/GCACTC 1 -- us2k10--------
    rs750269711,2
    F--150919380(+) ATCCCG/ATCTCA 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs3699464971,2
    C--150919383(+) CCCGT-/CAA   
      T
    /TCAA
    CAATC
    1 -- us2k10--------
    rs799592611,2
    F--150919454(+) TTCCAA/GGTTGT 1 -- us2k11Minor allele frequency- G:0.08WA 118
    rs10137071,2
    C--150919612(+) CACTTC/TTAACA 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs1506985831,2
    --150919719(+) AAAGGC/TGACTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PLEKHG1 (150920999 - 151164799 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for PLEKHG1 (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2732887CNV Deletion23290073
    esv1000462CNV Deletion20482838
    esv2732888CNV Deletion23290073
    esv2086893CNV Deletion18987734
    esv2292678CNV Deletion18987734
    esv2664886CNV Deletion23128226
    nsv5539CNV Insertion18451855
    nsv886774CNV Loss21882294
    nsv464080CNV Loss19166990
    nsv522403CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PLEKHG1
    DNA2.0 Custom Variant and Variant Library Synthesis for PLEKHG1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease from the University of Copenhagen DISEASES database for PLEKHG1:
    Panic disorder

    Find genes that share disorders with PLEKHG1           About GenesLikeMe

    Genetic Association Database (GAD): PLEKHG1
    Human Genome Epidemiology (HuGE) Navigator: PLEKHG1 (4 documents)

    Export disorders for PLEKHG1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PLEKHG1 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with PLEKHG1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1999)
    2. Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence. (PubMed id 22488850)1, 4 Zuo L....Luo X. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2012)
    3. Polymorphisms in predicted miRNA binding sites and osteoporosis. (PubMed id 20641033)1, 4 Lei S.F....Deng H.W. (J. Bone Miner. Res. 2011)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Genome-wide association study of panic disorder in the Japanese population. (PubMed id 19165232)1, 4 Otowa T....Okazaki Y. (J. Hum. Genet. 2009)
    6. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    7. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. (PubMed id 23535033)1 Sherva R....Green R.C. (amp 2014)
    8. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. (PubMed id 23972371)1 Franceschini N....Zhu X. (Am. J. Hum. Genet. 2013)
    9. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    10. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57480 HGNC: 20884 AceView: PLEKHG1 Ensembl:ENSG00000120278 euGenes: HUgn57480
    ECgene: PLEKHG1 H-InvDB: PLEKHG1

    (According to HUGE)
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    HUGE: KIAA1209

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PLEKHG1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PLEKHG1 gene:
    Search GeneIP for patents involving PLEKHG1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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