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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

PLEKHA5 Gene

protein-coding GIFtS: 49
GCID: GC12P019282

pleckstrin homology domain containing, family A member 5

Explore 2 diseases affiliated with
PLEKHA5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Pleckstrin Homology Domain Containing, Family A Member 5¹ ²		FLJ10667¹
PEPP2¹ ² ³ ⁵		Phosphoinositol 3-Phosphate-Binding Protein-2²
KIAA1686¹ ³ ⁵		Pleckstrin Homology Domain-Containing Family A Member 5²
PEPP-2² ³		Phosphoinositol 3-Phosphate-Binding Protein 2³
PH Domain-Containing Family A Member 5² ³

External Ids:	HGNC: 30036¹	Entrez Gene: 54477²	Ensembl: ENSG00000052126⁷	OMIM: 607770⁵	UniProtKB: Q9HAU0³

Export aliases for PLEKHA5 gene to outside databases

Previous GC identifers: GC12P019174 GC12P019052

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for PLEKHA5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_009714.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the PLEKHA5 gene promoter:
GR Pax-6 GR-beta Lmo2 Tal-1beta NF-kappaB E47 GR-alpha NF-kappaB1 ATF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PLEKHA5 promoter sequence

Search SABiosciences Chromatin IP Primers for PLEKHA5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PLEKHA5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p12 Ensembl cytogenetic band: 12p12.3 HGNC cytogenetic band: 12p12

PLEKHA5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PLEKHA5 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P019282: view genomic region (about GC identifiers)

Start:	19,282,630 bp from pter	End:	19,529,334 bp from pter
Size:	246,705 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PKHA5_HUMAN, Q9HAU0 (See protein sequence)

Recommended Name: Pleckstrin homology domain-containing family A member 5

Size: 1116 amino acids; 127464 Da

Subcellular location: Cytoplasm

Sequence caution: Sequence=AAH70174.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A

sequence; Sequence=BAA91742.1; Type=Frameshift; Positions=759; Sequence=BAB14419.1; Type=Erroneous initiation;

Sequence=BAB21777.2; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for PLEKHA5:

2DKP (3D)

Secondary accessions: A0JP03 E9PHQ3 Q6NSF8 Q8N3K6 Q96DY9 Q9BVR4 Q9C0H7 Q9H924 Q9NVK8

Alternative splicing: 6 isoforms: Q9HAU0-1 Q9HAU0-2 Q9HAU0-3 Q9HAU0-4 Q9HAU0-5 Q9HAU0-6 (Specifically expresssed in brain)

Explore the universe of human proteins at neXtProt for PLEKHA5: NX_Q9HAU0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9HAU0

PLEKHA5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (5 alternative transcripts):

NP_001137293.2 NP_001177789.2 NP_001243399.1 NP_001243716.1 NP_061885.2

ENSEMBL proteins:

ENSP00000439396 ENSP00000404296 ENSP00000299275 ENSP00000439673 ENSP00000446308

ENSP00000440371 ENSP00000441777 ENSP00000443553 ENSP00000325155 ENSP00000347560

ENSP00000352104 ENSP00000311239 ENSP00000400411 ENSP00000439837 ENSP00000440611

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	Uscn Proteins for PLEKHA5

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--
GO:0005737	cytoplasm	IEA	--

PLEKHA5 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for PLEKHA5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PLEKHA5 for domains About GeneDecksing

3 InterPro domains/families:

IPR001849 Pleckstrin_homology

IPR011993 PH_like_dom

IPR001202 WW_Rsp5_WWP

Graphical View of Domain Structure for InterPro Entry Q9HAU0

ProtoNet protein and cluster: Q9HAU0

1 Blocks protein family: IPB001849 Pleckstrin-like

UniProtKB/Swiss-Prot: PKHA5_HUMAN, Q9HAU0

Domain: Specifically interacts with PI3P, PI4P, PI5P, and PI(3,5)P2

Similarity: Contains 1 PH domain

Similarity: Contains 2 WW domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 2): PLEKHA5 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PLEKHA5
		8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate PLEKHA5 (see all 20):
		hsa-miR-320a hsa-miR-137 hsa-miR-376b hsa-miR-15a hsa-miR-421 hsa-miR-424 hsa-miR-3658 hsa-miR-3662

		SwitchGear 3'UTR luciferase reporter plasmid: PLEKHA5 3' UTR sequence

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLEKHA5

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	16713569
GO:0005543	phospholipid binding	--	--
GO:0005545	1-phosphatidylinositol binding	NAS	11001876

PLEKHA5 for ontologies About GeneDecksing

Animal Models:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Plekha5):

no phenotypic analysis

PLEKHA5 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PLEKHA5

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/72 Interacting proteins for PLEKHA5 (Q9HAU0^{1, 3} ENSP00000299275⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 72)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ATXN1	P54253¹^,³, ENSP00000244769⁴	EBI-945934,EBI-930964 I2D: score=1 STRING: ENSP00000244769
RBFOX1	Q9NWB1¹^,³, ENSP00000309117⁴	EBI-945934,EBI-1047634 I2D: score=1 STRING: ENSP00000309117
ATN1	P54259¹^,³, ENSP00000349076⁴	EBI-945934,EBI-945980 I2D: score=1 STRING: ENSP00000349076
C10orf118	Q7Z3E2³, ENSP00000358293⁴	I2D: score=3 STRING: ENSP00000358293
CEP350	Q5VT06³, ENSP00000356579⁴	I2D: score=3 STRING: ENSP00000356579

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

PLEKHA5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PLEKHA5
Search CenterWatch for drugs/clinical trials and news about PLEKHA5 / PKHA5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PLEKHA5 gene (5 alternative transcripts):

NM_001143821.2 NM_001190860.2 NM_001256470.1 NM_001256787.1 NM_019012.5

Unigene Cluster for PLEKHA5:

Pleckstrin homology domain containing, family A member 5

Hs.188614 [show with all ESTs]

Unigene Representative Sequence: NM_001143821

18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):

ENST00000540972(uc001rdz.4) ENST00000429027(uc010sie.2 uc001rec.1)

ENST00000299275(uc009zio.3) ENST00000538714(uc001rea.3) ENST00000535357

ENST00000538034 ENST00000538305 ENST00000536974(uc010sih.1) ENST00000534979

ENST00000510738 ENST00000538677 ENST00000538068 ENST00000537027 ENST00000538972

ENST00000317589 ENST00000355397(uc001reb.3 uc009zin.3) ENST00000359180

ENST00000309364

miRNA Products:		OriGene 3'-UTR Clone (see all 2): PLEKHA5 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PLEKHA5
		8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate PLEKHA5 (see all 20):
		hsa-miR-320a hsa-miR-137 hsa-miR-376b hsa-miR-15a hsa-miR-421 hsa-miR-424 hsa-miR-3658 hsa-miR-3662

		SwitchGear 3'UTR luciferase reporter plasmid: PLEKHA5 3' UTR sequence

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Additional cDNA sequence:

AB051473.2 AB642244.1 AF302150.1 AJ270694.1 AK001529.1 AK023127.1 AK026344.1 AK056054.1

AK294739.1 AK295151.1 AK296277.1 AK297391.1 AL834259.1 BC000969.2 BC004164.2 BC013133.2

BC044245.1 BC070174.1 BC127092.1

20 DOTS entries:

DT.313097 DT.97819412 DT.100823412 DT.95231459 DT.92458664 DT.91975606 DT.95271462 DT.75170814

DT.75103237 DT.100823414 DT.70104086 DT.92458658 DT.121210968 DT.441953 DT.99958994 DT.100665858

DT.100671797 DT.456210 DT.95271464 DT.99967003

24/226 AceView cDNA sequences (see all 226):

BE207328 AI499219 AA232094 CB153372 AI810566 AW264201 BP335984 NM_019012

CA394540 AA232093 BM992061 AA386119 BQ024068 AW439876 BQ021982 BF431537

CA436883 AI637851 AA232541 AI923050 BM693672 BC000969 AI611031 BF724511

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for PLEKHA5 (see all 12) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16	^	17a	·	17b	·	17c	^	18	^	19	^	20	^	21	^	22	^	23	^
SP1:																																	-		-				-		-
SP2:																													-		-		-		-				-		-
SP3:																													-		-		-		-				-		-
SP4:																																																			-
SP5:																																			-				-		-

ExUns:	24	^	25a	·	25b	^	26	^	27a	·	27b	^	28	^	29a	·	29b	·	29c	^	30a	·	30b	^	31a	·	31b	^	32a	·	32b	·	32c
SP1:			-
SP2:	-		-												-
SP3:	-		-												-
SP4:	-		-		-										-
SP5:

ECgene alternative splicing isoforms for PLEKHA5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PLEKHA5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAAATAAAT

About this image

PLEKHA5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Neural Tube

Metencephalon

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Posterior foregut-like cells (A scalable, suspensi...)

See PLEKHA5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PLEKHA5

SOURCE GeneReport for Unigene cluster: Hs.188614

UniProtKB/Swiss-Prot: PKHA5_HUMAN, Q9HAU0

Tissue specificity: Highly expressed in heart and kidney

SABiosciences Custom PCR Arrays for PLEKHA5

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for PLEKHA5 gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	PLEKHA5¹	pleckstrin homology domain containing, family A member 5 less	77.65(n) 78.69(a)		418183 XM_416414.3 XP_416414.3
lizard (Anolis carolinensis)	Reptilia	PLEKHA5⁶	--	74(a)	1 ↔ 1	5(9019702-9104011)
African clawed frog (Xenopus laevis)	Amphibia	Xl.11613²	Xenopus laevis transcribed sequence with weak similarity to protein pirJC5795 (H.sapiens) JC5795 CDEP protein - human less	74.27(n)		BJ067775.1
zebrafish (Danio rerio)	Actinopterygii	plekha5¹	pleckstrin homology domain containing, family A member 5 less	56.87(n) 53.21(a)		567300 XM_690591.4 XP_695683.3
fruit fly (Drosophila melanogaster)	Insecta	CG34383⁶	--	5(a)	1 → many	3R(9540931-9590389)

ENSEMBL Gene Tree for PLEKHA5 (if available)
TreeFam Gene Tree for PLEKHA5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for PLEKHA5 gene

PLEKHA6² PLEKHA4² PLEKHA7²

8 SIMAP similar genes for PLEKHA5 using alignment to 10 protein entries: PKHA5_HUMAN (see all proteins):

MAGI1 KIAA0053 MAGI2 PLEKHA7 MAGI3 FAM109A

NEDD4 NEDD4L

PLEKHA5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs201747116^1,2	C,	other	19436352(+)	`CCTTCC/G/TACTCA`	12	S	syn¹		1		EU	1323
rs117419780^1,2	C,F,	--	19280774(+)	`TTCTAC/TATCAT`	4	--	us2k¹		1		EA	120
rs182652557^1,2		--	19281090(+)	`CTTGTC/GTAATT`	4	--	us2k¹		0	--	--	--	--
rs149549095^1,2		--	19281123(+)	`TGGCCG/TCTCTT`	4	--	us2k¹		0	--	--	--	--
rs187007353^1,2		--	19281219(+)	`AAAGGA/GCATTG`	4	--	us2k¹		0	--	--	--	--
rs144132396^1,2		--	19281328(+)	`AGAGAC/TAGAGG`	4	--	us2k¹		0	--	--	--	--
rs191789002^1,2		--	19281358(+)	`AGTCAC/GAACAC`	4	--	us2k¹		0	--	--	--	--
rs139936786^1,2		--	19281362(+)	`AGAACA/GCACAC`	4	--	us2k¹		0	--	--	--	--
rs182162605^1,2		--	19281386(+)	`CTGTCC/TTACAT`	4	--	us2k¹		0	--	--	--	--
rs143352882^1,2		--	19281397(+)	`GGGCTC/TAGTTC`	4	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for PLEKHA5 (19282630 - 19529334 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for PLEKHA5
8 CNVs: 29615 49017 53918 5295 5296 29616 29617 6972

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PLEKHA5

DNA2.0 Custom Variant and Variant Library Synthesis for PLEKHA5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

PLEKHA5 for disorders           About GeneDecksing

OMIM gene information: 607770    OMIM disorders: --

2 diseases for PLEKHA5:    About MalaCards

ataxia melanoma

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(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for PLEKHA5 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with PLEKHA5)

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Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. (PubMed id 11001876)^{1, 2, 3} Dowler S.J.... Alessi D.R. (2000)
Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)^{1, 2, 3} Nagase T.... Ohara O. (2000)
Identification and characterization of splicing varia nts of PLEKHA5 (Plekha5) during brain development. (PubMed id 22037487)^{1, 2} Yamada K....Wakamatsu N. (2012)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)^{1, 2} Nakajima D.... Nagase T. (2002)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54477	HGNC: 30036	AceView: PLEKHA5	Ensembl:ENSG00000052126	euGenes: HUgn54477
ECgene: PLEKHA5	H-InvDB: PLEKHA5

(According to HUGE)
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HUGE: KIAA1686

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for PLEKHA5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for PLEKHA5 gene
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Patent Information for PLEKHA5 gene:
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PLEKHA5 Gene

pleckstrin homology domain containing, family A member 5

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PLEKHA5 Gene

pleckstrin homology domain containing, family A member 5

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