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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PLEKHA5 Gene

protein-coding   GIFtS: 51
GCID: GC12P019282

Pleckstrin Homology Domain Containing, Family A Member 5

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Pleckstrin Homology Domain Containing, Family A Member 51 2     KIAA16863 5
PEPP22 3 5     Phosphoinositol 3-Phosphate-Binding Protein-22
PEPP-22 3     Pleckstrin Homology Domain-Containing Family A Member 52
PH Domain-Containing Family A Member 52 3     Phosphoinositol 3-Phosphate-Binding Protein 23

External Ids:    HGNC: 300361   Entrez Gene: 544772   Ensembl: ENSG000000521267   OMIM: 6077705   UniProtKB: Q9HAU03   

Export aliases for PLEKHA5 gene to outside databases

Previous GC identifers: GC12P019174 GC12P019052


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for PLEKHA5 Gene: 
PLEKHA5 (pleckstrin homology domain containing, family A member 5) is a protein-coding gene. Diseases associated with PLEKHA5 include melanoma. GO annotations related to this gene include protein binding and 1-phosphatidylinositol binding. An important paralog of this gene is PLEKHA6.

Gene Wiki entry for PLEKHA5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_009714.17  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PLEKHA5 gene promoter:
         GR   Pax-6   GR-beta   Lmo2   Tal-1beta   NF-kappaB   E47   GR-alpha   NF-kappaB1   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPLEKHA5 promoter sequence
   Search SABiosciences Chromatin IP Primers for PLEKHA5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PLEKHA5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p12   Ensembl cytogenetic band:  12p12.3   HGNC cytogenetic band: 12p12

PLEKHA5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PLEKHA5 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P019282:  view genomic region     (about GC identifiers)

Start:
19,282,626 bp from pter      End:
19,529,334 bp from pter
Size:
246,709 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PKHA5_HUMAN, Q9HAU0 (See protein sequence)
Recommended Name: Pleckstrin homology domain-containing family A member 5  
Size: 1116 amino acids; 127464 Da
Subcellular location: Cytoplasm
Sequence caution: Sequence=AAH70174.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=BAA91742.1; Type=Frameshift; Positions=759; Sequence=BAB14419.1; Type=Erroneous
initiation; Sequence=BAB21777.2; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for PLEKHA5:
2DKP (3D)    
Secondary accessions: A0JP03 B4DGS1 E9PHQ3 F5H0I0 Q6NSF8 Q86ST7 Q8N3K6 Q96DY9 Q9BVR4 Q9C0H7
Q9H924 Q9NVK8
Alternative splicing: 8 isoforms:  Q9HAU0-1   Q9HAU0-2   Q9HAU0-3   Q9HAU0-4   Q9HAU0-5   Q9HAU0-6   Q9HAU0-7   Q9HAU0-8   
(No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PLEKHA5: NX_Q9HAU0

Explore proteomics data for PLEKHA5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9HAU0

  • PLEKHA5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PLEKHA5 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001137293.2  NP_001177789.2  NP_001243399.1  NP_001243716.1  NP_061885.2  

    ENSEMBL proteins: 
     ENSP00000439396   ENSP00000404296   ENSP00000299275   ENSP00000439673   ENSP00000446308  
     ENSP00000440371   ENSP00000441777   ENSP00000443553   ENSP00000325155   ENSP00000347560  
     ENSP00000352104   ENSP00000311239   ENSP00000400411   ENSP00000439837   ENSP00000440611  

    Human Recombinant Protein Products for PLEKHA5: 
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    Cloud-Clone Corp. Proteins for PLEKHA5 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm IEA--

    PLEKHA5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PLEKH: Pleckstrin homology (PH) domain containing

    3 InterPro protein domains:
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom
     IPR001202 WW_dom

    Graphical View of Domain Structure for InterPro Entry Q9HAU0

    ProtoNet protein and cluster: Q9HAU0

    1 Blocks protein domain: IPB001849 Pleckstrin-like

    UniProtKB/Swiss-Prot: PKHA5_HUMAN, Q9HAU0
    Domain: Specifically interacts with PI3P, PI4P, PI5P, and PI(3,5)P2
    Similarity: Contains 1 PH domain
    Similarity: Contains 2 WW domains


    PLEKHA5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16713569
    GO:0005543phospholipid binding ----
    GO:00055451-phosphatidylinositol binding NAS11001876
         
    PLEKHA5 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Plekha5):
     no phenotypic analysis 

    PLEKHA5 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PLEKHA5 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PLEKHA5 
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    SwitchGear 3'UTR luciferase reporter plasmidPLEKHA5 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PLEKHA5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/72 Interacting proteins for PLEKHA5 (Q9HAU01, 3 ENSP000002992754) via UniProtKB, MINT, STRING, and/or I2D (see all 72)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542531, 3, ENSP000002447694EBI-945934,EBI-930964 I2D: score=1 STRING: ENSP00000244769
    RBFOX1Q9NWB11, 3, ENSP000003091174EBI-945934,EBI-945906 I2D: score=1 STRING: ENSP00000309117
    ATN1P542591, 3, ENSP000003490764EBI-945934,EBI-945980 I2D: score=1 STRING: ENSP00000349076
    C10orf118Q7Z3E23, ENSP000003582934I2D: score=3 STRING: ENSP00000358293
    CEP350Q5VT063, ENSP000003565794I2D: score=3 STRING: ENSP00000356579
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    PLEKHA5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PLEKHA5 (PKHA5)

    Search CenterWatch for drugs/clinical trials and news about PLEKHA5 / PKHA5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PLEKHA5 gene (5 alternative transcripts): 
    NM_001143821.2  NM_001190860.2  NM_001256470.1  NM_001256787.1  NM_019012.5  

    Unigene Cluster for PLEKHA5:

    Pleckstrin homology domain containing, family A member 5
    Hs.188614  [show with all ESTs]
    Unigene Representative Sequence: NM_001143821
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000540972(uc001rdz.4) ENST00000429027(uc010sie.2 uc001rec.1)
    ENST00000299275(uc009zio.3) ENST00000538714(uc001rea.3) ENST00000535357
    ENST00000538034 ENST00000538305 ENST00000536974(uc010sih.1) ENST00000534979
    ENST00000510738 ENST00000538677 ENST00000538068 ENST00000537027 ENST00000538972
    ENST00000317589 ENST00000355397(uc001reb.3 uc009zin.3) ENST00000359180
    ENST00000309364
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    Inhib. RNA
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    Additional mRNA sequence: 

    AB051473.2 AB642244.1 AF302150.1 AJ270694.1 AK001529.1 AK023127.1 AK026344.1 AK056054.1 
    AK294739.1 AK295151.1 AK296277.1 AK297391.1 AL834259.1 BC000969.2 BC004164.2 BC013133.2 
    BC044245.1 BC070174.1 BC127092.1 

    20 DOTS entries:

    DT.313097  DT.97819412  DT.100823412  DT.95231459  DT.92458664  DT.91975606  DT.95271462  DT.75170814 
    DT.75103237  DT.100823414  DT.70104086  DT.92458658  DT.121210968  DT.441953  DT.99958994  DT.100665858 
    DT.100671797  DT.456210  DT.95271464  DT.99967003 

    24/226 AceView cDNA sequences (see all 226):

    AL600061 AI499219 BM693672 NM_019012 AI636889 BP335984 CA394540 AI611031 
    AA410224 BE207328 AA232541 AW572377 BF724511 CA436883 AI637851 AW439876 
    AI923050 BQ021982 AI810566 AA232093 BF431537 T59650 CB153372 AA232094 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for PLEKHA5 (see all 12)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b · 17c ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^
    SP1:                                                                                                  -     -           -     -                                 
    SP2:                                                                                      -     -     -     -           -     -                                 
    SP3:                                                                                      -     -     -     -           -     -                                 
    SP4:                                                                                                                                                        -   
    SP5:                                                                                                        -           -     -                                 

    ExUns: 24 ^ 25a · 25b ^ 26 ^ 27a · 27b ^ 28 ^ 29a · 29b · 29c ^ 30a · 30b ^ 31a · 31b ^ 32a · 32b · 32c
    SP1:        -                                                                                             
    SP2:  -     -                                   -                                                         
    SP3:  -     -                                   -                                                         
    SP4:  -     -     -                             -                                                         
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for PLEKHA5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PLEKHA5 expression in normal human tissues (normalized intensities)      PLEKHA5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAAATAAAT
    PLEKHA5 Expression
    About this image


    PLEKHA5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             ganglion/cranial/facial VII   
     
     Blood (Hematopoietic System)    fully expand to see all 3 entries
             Natural Killer Cells Peripheral Blood
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
             brain/midbrain/lateral wall   
     
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   

    See PLEKHA5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PLEKHA5

    SOURCE GeneReport for Unigene cluster: Hs.188614

    UniProtKB/Swiss-Prot: PKHA5_HUMAN, Q9HAU0
    Tissue specificity: Highly expressed in heart and kidney

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PLEKHA5 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Plekha51 , 5 pleckstrin homology domain containing, family A member more1, 5 82.96(n)1
    84.89(a)1
      6 (70.34 cM)5
    1091351  NM_144920.31  NP_659169.31 
     1404240995 
    chicken
    (Gallus gallus)
    Aves PLEKHA51 pleckstrin homology domain containing, family A member more 77.65(n)
    78.69(a)
      418183  XM_416414.3  XP_416414.3 
    lizard
    (Anolis carolinensis)
    Reptilia PLEKHA56
    pleckstrin homology domain containing, family A me...
    76(a)
    1 ↔ 1
    5(9017528-9221493)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.116132 Xenopus laevis transcribed sequence with weak similarity more 74.27(n)    BJ067775.1 
    zebrafish
    (Danio rerio)
    Actinopterygii plekha51 pleckstrin homology domain containing, family A member more 56.87(n)
    53.21(a)
      567300  XM_690591.4  XP_695683.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG343836
    --
    7(a)
    1 → many
    3R(9540931-9590389)


    ENSEMBL Gene Tree for PLEKHA5 (if available)
    TreeFam Gene Tree for PLEKHA5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PLEKHA5 gene
    PLEKHA62  PLEKHA42  PLEKHA72  
    3 SIMAP similar genes for PLEKHA5 using alignment to 8 protein entries:     PKHA5_HUMAN (see all proteins):
    KIAA0053    PLEKHA7    FAM109A

    PLEKHA5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5371 SNPs in PLEKHA5 are shown (see all 5371)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2017471161,2
    Cuntested119436352(+) CCTTCC/G/TACTCA 8 S syn11EU 1323
    rs609752661,2
    C--19161693(+) TGGCA-/GTA   
      GAACTT
    CACTG
    4 -- int10--------
    rs39836101,2
    C--19172923(+) TTTTT-/GT/TG 
            
    TTGTT
    4 -- int11CSA 2
    rs562349411,2
    C--19181959(+) TTTTT-/T/TT  
            
    GGTTT
    4 -- int11NA 2
    rs1174197801,2
    C,F--19280774(+) TTCTAC/TATCAT 4 -- us2k11Minor allele frequency- T:0.02EA 120
    rs1826525571,2
    --19281090(+) CTTGTC/GTAATT 4 -- us2k10--------
    rs1495490951,2
    --19281123(+) TGGCCG/TCTCTT 4 -- us2k10--------
    rs1870073531,2
    C--19281219(+) AAAGGA/GCATTG 4 -- us2k10--------
    rs1441323961,2
    --19281328(+) AGAGAC/TAGAGG 4 -- us2k10--------
    rs1917890021,2
    C--19281358(+) AGTCAC/GAACAC 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for PLEKHA5 (19282626 - 19529334 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/17 variations for PLEKHA5 (see all 17):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2663408CNV Deletion23128226
    esv2745617CNV Deletion23290073
    esv2422206CNV Duplication17116639
    esv2422261CNV Duplication17116639
    esv2422498CNV Duplication17116639
    esv1008021CNV Insertion20482838
    esv1027404CNV Insertion17803354
    nsv832346CNV Loss17160897
    nsv428274CNV Loss18775914
    nsv898851CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607770    OMIM disorders: --

    2 diseases for PLEKHA5:    About MalaCards
    melanoma    


    PLEKHA5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): PLEKHA5

    Export disorders for PLEKHA5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PLEKHA5 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with PLEKHA5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. (PubMed id 11001876)1, 2, 3 Dowler S.J.... Alessi D.R. (2000)
    2. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (2000)
    3. Identification and characterization of splicing varia nts of PLEKHA5 (Plekha5) during brain development. (PubMed id 22037487)1, 2 Yamada K....Wakamatsu N. (2012)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54477 HGNC: 30036 AceView: PLEKHA5 Ensembl:ENSG00000052126 euGenes: HUgn54477
    ECgene: PLEKHA5 H-InvDB: PLEKHA5

    (According to HUGE)
    About This Section
    HUGE: KIAA1686

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PLEKHA5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PLEKHA5 gene:
    Search GeneIP for patents involving PLEKHA5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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