Aliases for PLCL1 Gene
External Ids for PLCL1 Gene
Previous HGNC Symbols for PLCL1 Gene
Previous GeneCards Identifiers for PLCL1 Gene
GeneCards Summary for PLCL1 Gene
PLCL1 (Phospholipase C Like 1 (Inactive)) is a Protein Coding gene. Among its related pathways are GABAergic synapse and Proton Pump Inhibitor Pathway, Pharmacodynamics. GO annotations related to this gene include calcium ion binding and phosphoric diester hydrolase activity. An important paralog of this gene is PLCL2.
UniProtKB/Swiss-Prot for PLCL1 Gene
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.