Aliases for PLCB2 Gene
External Ids for PLCB2 Gene
Previous GeneCards Identifiers for PLCB2 Gene
GeneCards Summary for PLCB2 Gene
PLCB2 (Phospholipase C Beta 2) is a Protein Coding gene. Diseases associated with PLCB2 include Prostate Leiomyosarcoma. Among its related pathways are NFAT and Cardiac Hypertrophy and Basal cell carcinoma. GO annotations related to this gene include calcium ion binding and phosphoric diester hydrolase activity. An important paralog of this gene is PLCB1.
UniProtKB/Swiss-Prot for PLCB2 Gene
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. There are four major classes; phospholipase A, phospholipase B, phosphoinositide-specific phospholipase C and phospholipase D.