Aliases for PLCB2 Gene
External Ids for PLCB2 Gene
Previous GeneCards Identifiers for PLCB2 Gene
GeneCards Summary for PLCB2 Gene
PLCB2 (Phospholipase C Beta 2) is a Protein Coding gene. Diseases associated with PLCB2 include Prostate Leiomyosarcoma. Among its related pathways are Platelet activation and Neuropathic Pain-Signaling in Dorsal Horn Neurons. GO annotations related to this gene include calcium ion binding and phosphoric diester hydrolase activity. An important paralog of this gene is PLCB3.
UniProtKB/Swiss-Prot for PLCB2 Gene
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. There are four major classes; phospholipase A, phospholipase B, phosphoinositide-specific phospholipase C and phospholipase D.