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PLBD1 Gene

protein-coding   GIFtS: 46
GCID: GC12M014657

Phospholipase B Domain Containing 1

  Search for PLBD1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Phospholipase B Domain Containing 11 2     Phospholipase B-Like 12
Lamina Ancestor Homolog 12 3     PLB Homolog 12
Phospholipase B Domain-Containing Protein 12 3     Putative Phospholipase B-Like 12
LAMA-Like Protein 12 3     EC 3.1.1.-3
PLB Homolog 1 (Dictyostelium)1     EC 3.1.18

External Ids:    HGNC: 262151   Entrez Gene: 798872   Ensembl: ENSG000001213167   UniProtKB: Q6P4A83   

Export aliases for PLBD1 gene to outside databases

Previous GC identifers: GC12M014548 GC12M014425


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PLBD1 Gene:
PLBD1 (phospholipase B domain containing 1) is a protein-coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is PLBD2.

UniProtKB/Swiss-Prot: PLBL1_HUMAN, Q6P4A8
Function: In view of the small size of the putative binding pocket, it has been proposed that it may act as an
amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids,
including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NC_018923.2  NT_009714.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the PLBD1 gene promoter:
         c-Fos   USF1   AP-1   SREBP-1c   USF2   USF-1:USF-2   SREBP-1b   SREBP-1a   USF-1   c-Jun   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for PLBD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PLBD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.1   Ensembl cytogenetic band:  12p13.1   HGNC cytogenetic band: 12p13.1

PLBD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PLBD1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M014657:  view genomic region     (about GC identifiers)

Start:
14,656,595 bp from pter      End:
14,721,283 bp from pter
Size:
64,689 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PLBL1_HUMAN, Q6P4A8 (See protein sequence)
Recommended Name: Phospholipase B-like 1 precursor  
Size: 553 amino acids; 63255 Da
Subunit: May form a homodimer, each monomer is composed of a chain A and a chain B
Sequence caution: Sequence=AAH00909.2; Type=Erroneous initiation; Sequence=BAB15442.1; Type=Erroneous initiation;
Secondary accessions: A8K4E9 Q9BVV3 Q9H625

Explore the universe of human proteins at neXtProt for PLBD1: NX_Q6P4A8

Explore proteomics data for PLBD1 at MOPED

Post-translational modifications: 

  • The maturation cleavages that produces chains A and B are required to open the putative substrate binding pocket.
    Both chains A and B remain associated in the mature protein1
  • Glycosylation2 at Asn71, Asn308, Asn366, Asn411, Asn526
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for PLBD1 (Q6P4A8) (see all 5)
     GYWPSYN  NSGTYNN  LSNEIIMF  TNLYPQLI 


    See PLBD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079105.4  
    ENSEMBL proteins: 
     ENSP00000240617   ENSP00000441278   ENSP00000438367  
    Reactome Protein details: Q6P4A8

    PLBD1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for PLBD1

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    PLBD1 Assay Products:

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    Cloud-Clone Corp. CLIAs for PLBD1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007000 PLipase_B-like

    Graphical View of Domain Structure for InterPro Entry Q6P4A8

    ProtoNet protein and cluster: Q6P4A8

    UniProtKB/Swiss-Prot: PLBL1_HUMAN, Q6P4A8
    Similarity: Belongs to the phospholipase B-like family


    PLBD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PLBL1_HUMAN, Q6P4A8
    Function: In view of the small size of the putative binding pocket, it has been proposed that it may act as an
    amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids,
    including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids
    Biophysicochemical properties: pH dependence: Optimum pH is 7.4;

         Enzyme Numbers (IUBMB): EC 3.1.12 EC 3.1.1.-1

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
         
    PLBD1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PLBD1:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PLBD1
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    1 qRT-PCR Assays for microRNA that regulate PLBD1:
    hsa-miR-9
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLBD1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PLBL1_HUMAN, Q6P4A8: Lysosome (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    cytosol4
    golgi apparatus2
    endoplasmic reticulum1
    lysosome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005764lysosome IEA--
    GO:0005829cytosol TAS--

    PLBD1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PLBD1 About    
    See pathways by source

    SuperPathContained pathways About
    1Glycerophospholipid biosynthesis
    Glycerophospholipid biosynthesis0.64
    Hydrolysis of LPC0.00
    Phospholipid metabolism0.64
    Acyl chain remodelling of PI0.00
    2Acyl chain remodelling of PC
    Acyl chain remodelling of PE0.85
    Acyl chain remodelling of PC0.85
    3Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    4 Reactome Pathways for PLBD1
        Acyl chain remodelling of PE
    Acyl chain remodelling of PC
    Hydrolysis of LPC
    Acyl chain remodelling of PI



    PLBD1 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PLBD1
    Interactions:

        Search GeneGlobe Interaction Network for PLBD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for PLBD1 (ENSP000002406174) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GPCPD1ENSP000003683054STRING: ENSP00000368305
    LPCAT1ENSP000002834154STRING: ENSP00000283415
    LPCAT2ENSP000002621344STRING: ENSP00000262134
    LPCAT4ENSP000003173004STRING: ENSP00000317300
    MBOAT1ENSP000003249444STRING: ENSP00000324944
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0016042lipid catabolic process IEA--
    GO:0036149phosphatidylinositol acyl-chain remodeling TAS--
    GO:0036151phosphatidylcholine acyl-chain remodeling TAS--
    GO:0036152phosphatidylethanolamine acyl-chain remodeling TAS--

    PLBD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PLBD1 (PLBL1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PLBD1 gene: 
    NM_024829.5  

    Unigene Cluster for PLBD1:

    Phospholipase B domain containing 1
    Hs.131933  [show with all ESTs]
    Unigene Representative Sequence: NM_024829
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000240617(uc001rcc.1) ENST00000541800 ENST00000541618 ENST00000540572

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate PLBD1:
    hsa-miR-9
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Primer
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    OriGene qPCR primer pairs and template standards for PLBD1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PLBD1
      QuantiTect SYBR Green Assays in human, mouse, rat PLBD1
      QuantiFast Probe-based Assays in human, mouse, rat PLBD1

    Additional mRNA sequence: 

    AK026315.1 AK225458.1 AK290914.1 BC000909.2 BC063561.1 

    7 DOTS entries:

    DT.215545  DT.121150828  DT.75101935  DT.91734534  DT.121150822  DT.75102752  DT.91817248 

    Selected AceView cDNA sequences (see all 194):

    CR602008 CR615954 BU581527 BG572884 AA513409 BM142639 BQ101253 BX116782 
    AA252038 BX643808 AW629861 BU736309 BG542885 BG110795 BM263066 AW169974 
    AA931082 AA669072 CR621086 AA298290 CR598292 CD369182 AA307797 BU619049 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PLBD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAACCAATTT
    PLBD1 Expression
    About this image


    PLBD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Testis (Reproductive System)
             Sertoli cells Seminiferous Tubules
     
     Adipose (Muscoskeletal System)
             Visceral White Adipose
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Colon (Gastrointestinal Tract)
    PLBD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PLBD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.131933

    UniProtKB/Swiss-Prot: PLBL1_HUMAN, Q6P4A8
    Tissue specificity: Expressed in neutrophils and monocytes

        Custom PCR Arrays for PLBD1
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PLBD1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Plbd11 , 5 phospholipase B domain containing 11, 5 80.95(n)1
    80.5(a)1
      6 (66.59 cM)5
    668571  NM_025806.21  NP_080082.11 
     1366120705 
    chicken
    (Gallus gallus)
    Aves PLBD11 phospholipase B domain containing 1 70.84(n)
    70.84(a)
      417967  XM_416206.4  XP_416206.3 
    lizard
    (Anolis carolinensis)
    Reptilia PLBD16
    phospholipase B domain containing 1
    67(a)
    1 ↔ 1
    GL343714.1(81017-108756)
    zebrafish
    (Danio rerio)
    Actinopterygii plbd11 phospholipase B domain containing 1 60.41(n)
    58.89(a)
      569736  NM_001130791.1  NP_001124263.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta lama6
    lamina ancestor
    16(a)
    1 → many
    3L(5336719-5349023)
    worm
    (Caenorhabditis elegans)
    Secernentea Y37D8A.26
    F09B12.36
    (see all 3)
    Protein F09B12.3 (F09B12.3) mRNA, complete cds
    (see all 3)
    31(a)
    29(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    III(12820141-12825651) WBGene00012544
    X(15095335-15097954) WBGene00008607


    ENSEMBL Gene Tree for PLBD1 (if available)
    TreeFam Gene Tree for PLBD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PLBD1 gene
    PLBD22  

    PLBD1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PLBD1 (see all 1265)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1898658771,2
    --14656124(+) TGTATC/TGTATG 1 -- int10--------
    rs1829788121,2
    --14656340(+) CACTCG/TTCTCA 1 -- int10--------
    rs782049031,2
    C--14656507(+) TTAGTG/ATTATT 1 -- int12Minor allele frequency- A:0.21CSA WA 120
    rs38383511,2
    C--14656611(+) GACAA-/ATTAA 
            
    TATAT
    2 -- ut311Minor allele frequency- ATTAA:0.00NA 2
    rs1136733311,2
    C,F--14656732(+) AATTGG/ATTTCA 2 /P /S mis13Minor allele frequency- A:0.00CSA NA EU 5871
    rs16001,2,,4
    C,F,O,A,H--14656768(+) CTCTGG/CCATGC 2 /P /A mis122Minor allele frequency- C:0.48MN NA EA NS WA CSA EU 8601
    rs1417676191,2
    C,F--14656783(+) ATGTAG/CAGTTT 2 /L /V mis11Minor allele frequency- C:0.00NA 4552
    rs1454133421,2
    C,F--14656797(+) TGAAAC/TGGTCC 2 H R mis11Minor allele frequency- T:0.01NA 4552
    rs1381535981,2
    C--14656911(+) GAGGAC/GATTTT 1 -- int10--------
    rs746224391,2
    C,F--14656931(+) TCGTTC/GAGCAA 1 -- int13Minor allele frequency- G:0.06WA NA EA 358

    HapMap Linkage Disequilibrium report for PLBD1 (14656595 - 14721283 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for PLBD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv618CNV Loss18451855
    nsv470269CNV Gain18288195
    nsv469119CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PLBD1
    DNA2.0 Custom Variant and Variant Library Synthesis for PLBD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PLBD1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with PLBD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The identification of a phospholipase B precursor in human neutrophils. (PubMed id 19019078)1, 2, 3 Xu S.... Venge P. (FEBS J. 2009)
    2. Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast. (PubMed id 15193148)1, 3 Morgan C.P....Cockcroft S. (Biochem. J. 2004)
    3. Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). (PubMed id 22952603)1 Hart A.B....Palmer A.A. (PLoS ONE 2012)
    4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. ErbB2-associated changes in the lysosomal proteome. (PubMed id 21674799)1 Nylandsted J....JAoAottelAo M. (Proteomics 2011)
    7. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (J. Proteome Res. 2009)
    8. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79887 HGNC: 26215 AceView: FLJ22662 Ensembl:ENSG00000121316 euGenes: HUgn79887
    ECgene: PLBD1 H-InvDB: PLBD1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for PLBD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PLBD1 gene:
    Search GeneIP for patents involving PLBD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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