Aliases for PLB1 Gene
External Ids for PLB1 Gene
Previous GeneCards Identifiers for PLB1 Gene
GeneCards Summary for PLB1 Gene
PLB1 (Phospholipase B1) is a Protein Coding gene. Diseases associated with PLB1 include amyotrophic lateral sclerosis 3 and cryptococcosis. Among its related pathways are Signaling by GPCR and Metabolism. GO annotations related to this gene include hydrolase activity, acting on ester bonds and lysophospholipase activity.
UniProtKB/Swiss-Prot for PLB1 Gene
Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity).