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Aliases for PLAC8L1 Gene

Aliases for PLAC8L1 Gene

  • PLAC8-Like 1 2 3

External Ids for PLAC8L1 Gene

Previous GeneCards Identifiers for PLAC8L1 Gene

  • GC05M145444
  • GC05M140610
  • GC05M145463

Summaries for PLAC8L1 Gene

GeneCards Summary for PLAC8L1 Gene

PLAC8L1 (PLAC8-Like 1) is a Protein Coding gene. An important paralog of this gene is PLAC8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PLAC8L1 Gene

Genomics for PLAC8L1 Gene

Regulatory Elements for PLAC8L1 Gene

Genomic Location for PLAC8L1 Gene

Chromosome:
5
Start:
146,084,149 bp from pter
End:
146,104,383 bp from pter
Size:
20,235 bases
Orientation:
Minus strand

Genomic View for PLAC8L1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PLAC8L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PLAC8L1 Gene

Proteins for PLAC8L1 Gene

  • Protein details for PLAC8L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A1L4L8-PL8L1_HUMAN
    Recommended name:
    PLAC8-like protein 1
    Protein Accession:
    A1L4L8

    Protein attributes for PLAC8L1 Gene

    Size:
    177 amino acids
    Molecular mass:
    19885 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PLAC8L1 Gene

Proteomics data for PLAC8L1 Gene at MOPED

Post-translational modifications for PLAC8L1 Gene

No Post-translational modifications

Other Protein References for PLAC8L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PLAC8L1 Gene

Domains & Families for PLAC8L1 Gene

Protein Domains for PLAC8L1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PLAC8L1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A1L4L8

UniProtKB/Swiss-Prot:

PL8L1_HUMAN :
  • Belongs to the cornifelin family.
Family:
  • Belongs to the cornifelin family.
genes like me logo Genes that share domains with PLAC8L1: view

No data available for Gene Families for PLAC8L1 Gene

Function for PLAC8L1 Gene

Phenotypes for PLAC8L1 Gene

GenomeRNAi human phenotypes for PLAC8L1:
genes like me logo Genes that share phenotypes with PLAC8L1: view

Animal Model Products

CRISPR Products

miRNA for PLAC8L1 Gene

miRTarBase miRNAs that target PLAC8L1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PLAC8L1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for PLAC8L1 Gene

Localization for PLAC8L1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PLAC8L1 Gene

Pathways & Interactions for PLAC8L1 Gene

SuperPathways for PLAC8L1 Gene

No Data Available

Interacting Proteins for PLAC8L1 Gene

Gene Ontology (GO) - Biological Process for PLAC8L1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PLAC8L1 Gene

Drugs & Compounds for PLAC8L1 Gene

No Compound Related Data Available

Transcripts for PLAC8L1 Gene

mRNA/cDNA for PLAC8L1 Gene

(3) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PLAC8L1 Gene

PLAC8-like 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PLAC8L1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PLAC8L1 Gene

No ASD Table

Relevant External Links for PLAC8L1 Gene

GeneLoc Exon Structure for
PLAC8L1
ECgene alternative splicing isoforms for
PLAC8L1

Expression for PLAC8L1 Gene

mRNA expression in normal human tissues for PLAC8L1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for PLAC8L1 Gene

This gene is overexpressed in Testis (x14.0).

SOURCE GeneReport for Unigene cluster for PLAC8L1 Gene Hs.162369

genes like me logo Genes that share expression patterns with PLAC8L1: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for PLAC8L1 Gene

Orthologs for PLAC8L1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PLAC8L1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia PLAC8L1 35
  • 86.06 (n)
  • 81.36 (a)
PLAC8L1 36
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia PLAC8L1 35
  • 81.17 (n)
  • 75.14 (a)
PLAC8L1 36
  • 75 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Plac8l1 35
  • 80.23 (n)
  • 77.97 (a)
Plac8l1 16
Plac8l1 36
  • 78 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia PLAC8L1 35
  • 98.68 (n)
  • 97.74 (a)
PLAC8L1 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Plac8l1 35
  • 82.86 (n)
  • 81.36 (a)
oppossum
(Monodelphis domestica)
Mammalia PLAC8L1 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia PLAC8L1 36
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia PLAC8L1 36
  • 53 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii plac8l1 35
  • 59.89 (n)
  • 53.39 (a)
plac8l1 36
  • 43 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 25 (a)
OneToMany
Species with no ortholog for PLAC8L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for PLAC8L1 Gene

ENSEMBL:
Gene Tree for PLAC8L1 (if available)
TreeFam:
Gene Tree for PLAC8L1 (if available)

Paralogs for PLAC8L1 Gene

Paralogs for PLAC8L1 Gene

(2) SIMAP similar genes for PLAC8L1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with PLAC8L1: view

Variants for PLAC8L1 Gene

Sequence variations from dbSNP and Humsavar for PLAC8L1 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
VAR_037245 -

Structural Variations from Database of Genomic Variants (DGV) for PLAC8L1 Gene

Variant ID Type Subtype PubMed ID
nsv883006 CNV Loss 21882294

Variation tolerance for PLAC8L1 Gene

Residual Variation Intolerance Score: 72.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.44; 54.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PLAC8L1 Gene

HapMap Linkage Disequilibrium report
PLAC8L1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PLAC8L1 Gene

Disorders for PLAC8L1 Gene

Relevant External Links for PLAC8L1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PLAC8L1
genes like me logo Genes that share disorders with PLAC8L1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PLAC8L1 Gene

Publications for PLAC8L1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for PLAC8L1 Gene

Sources for PLAC8L1 Gene

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