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Aliases for PLAC4 Gene

Aliases for PLAC4 Gene

  • Placenta-Specific 4 2 3
  • C21orf115 3 4
  • Chromosome 21 Open Reading Frame 115 2
  • Placenta-Specific Protein 4 3
  • D21S418E 4
  • PRED78 3

External Ids for PLAC4 Gene

Previous Symbols for PLAC4 Gene

  • C21orf115

Summaries for PLAC4 Gene

GeneCards Summary for PLAC4 Gene

PLAC4 (Placenta-Specific 4) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PLAC4 Gene

Genomics for PLAC4 Gene

Genomic Location for PLAC4 Gene

Start:
41,175,231 bp from pter
End:
41,186,788 bp from pter
Size:
11,558 bases
Orientation:
Minus strand

Genomic View for PLAC4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PLAC4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PLAC4 Gene

Regulatory Elements for PLAC4 Gene

Proteins for PLAC4 Gene

  • Protein details for PLAC4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WY50-PLAC4_HUMAN
    Recommended name:
    Placenta-specific protein 4
    Protein Accession:
    Q8WY50
    Secondary Accessions:

    Protein attributes for PLAC4 Gene

    Size:
    150 amino acids
    Molecular mass:
    16680 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PLAC4 Gene

Proteomics data for PLAC4 Gene at MOPED

Post-translational modifications for PLAC4 Gene

No Post-translational modifications

Other Protein References for PLAC4 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for PLAC4 Gene

Domains for PLAC4 Gene

Protein Domains for PLAC4 Gene

ProtoNet:
genes like me logo Genes that share domains with PLAC4: view

No data available for Gene Families and UniProtKB/Swiss-Prot for PLAC4 Gene

Function for PLAC4 Gene

Phenotypes for PLAC4 Gene

GenomeRNAi human phenotypes for PLAC4:
genes like me logo Genes that share phenotypes with PLAC4: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for PLAC4 Gene

Localization for PLAC4 Gene

No data available for Gene Ontology (GO) - Cellular Components for PLAC4 Gene

Pathways for PLAC4 Gene

SuperPathways for PLAC4 Gene

No Data Available

Interacting Proteins for PLAC4 Gene

Gene Ontology (GO) - Biological Process for PLAC4 Gene

None

No data available for Pathways by source for PLAC4 Gene

Transcripts for PLAC4 Gene

mRNA/cDNA for PLAC4 Gene

Unigene Clusters for PLAC4 Gene

Placenta-specific 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PLAC4 Gene

No ASD Table

Relevant External Links for PLAC4 Gene

GeneLoc Exon Structure for
PLAC4
ECgene alternative splicing isoforms for
PLAC4

Expression for PLAC4 Gene

mRNA expression in normal human tissues for PLAC4 Gene

mRNA differential expression in normal tissues according to GTEx for PLAC4 Gene

This gene is overexpressed in Esophagus - Mucosa (7.1) and Minor Salivary Gland (5.7).

SOURCE GeneReport for Unigene cluster for PLAC4 Gene Hs.472492

mRNA Expression by UniProt/SwissProt for PLAC4 Gene

Q8WY50-PLAC4_HUMAN
Tissue specificity: Expressed in placental syncytiotrophoblast and choriocarcinoma cells.
genes like me logo Genes that share expressions with PLAC4: view

Orthologs for PLAC4 Gene

Evolution for PLAC4 Gene

ENSEMBL:
Gene Tree for PLAC4 (if available)
TreeFam:
Gene Tree for PLAC4 (if available)

No data available for Orthologs for PLAC4 Gene

Paralogs for PLAC4 Gene

Selected SIMAP similar genes for PLAC4 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with PLAC4: view

No data available for Paralogs for PLAC4 Gene

Variants for PLAC4 Gene

Structural Variations from Database of Genomic Variants (DGV) for PLAC4 Gene

Variant ID Type Subtype PubMed ID
nsv7347 OTHER Inversion 18451855

Relevant External Links for PLAC4 Gene

HapMap Linkage Disequilibrium report
PLAC4

No data available for Sequence variations from dbSNP and Humsavar for PLAC4 Gene

Disorders for PLAC4 Gene

Relevant External Links for PLAC4

Genetic Association Database (GAD)
PLAC4
Human Genome Epidemiology (HuGE) Navigator
PLAC4
genes like me logo Genes that share disorders with PLAC4: view

No data available for UniProtKB/Swiss-Prot for PLAC4 Gene

Publications for PLAC4 Gene

  1. Synergy of total PLAC4 RNA concentration and measurement of the RNA single-nucleotide polymorphism allelic ratio for the noninvasive prenatal detection of trisomy 21. (PMID: 19892844) Tsui N.B. … Lo Y.M. (Clin. Chem. 2010) 3 23
  2. D21S418E identifies a cAMP-regulated gene located on chromosome 21q22.3 that is expressed in placental syncytiotrophoblast and choriocarcinoma cells. (PMID: 8406465) Kido S. … Strauss J.F. III (Genomics 1993) 3 4
  3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 49
  4. PLAC4 is upregulated in severe early onset preeclampsia and upregulated with syncytialisation but not hypoxia. (PMID: 23312075) Tuohey L. … Kaitu'u-Lino T.J. (Placenta 2013) 3
  5. Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies. (PMID: 23903356) Hayes M.G. … Lowe W.L. (Diabetes 2013) 3

Products for PLAC4 Gene

Sources for PLAC4 Gene

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