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Aliases for PLAC4 Gene

Aliases for PLAC4 Gene

  • Placenta Specific 4 2 3 5
  • C21orf115 3 4
  • Chromosome 21 Open Reading Frame 115 2
  • Placenta-Specific 4 3
  • D21S418E 4
  • PRED78 3

External Ids for PLAC4 Gene

Previous HGNC Symbols for PLAC4 Gene

  • C21orf115

Previous GeneCards Identifiers for PLAC4 Gene

  • GC21U990111
  • GC21M041469
  • GC21M041470
  • GC21M042547

Summaries for PLAC4 Gene

GeneCards Summary for PLAC4 Gene

PLAC4 (Placenta Specific 4) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PLAC4 Gene

Genomics for PLAC4 Gene

Regulatory Elements for PLAC4 Gene

Genomic Location for PLAC4 Gene

Chromosome:
21
Start:
41,175,231 bp from pter
End:
41,185,239 bp from pter
Size:
10,009 bases
Orientation:
Minus strand

Genomic View for PLAC4 Gene

Genes around PLAC4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PLAC4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PLAC4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PLAC4 Gene

Proteins for PLAC4 Gene

  • Protein details for PLAC4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WY50-PLAC4_HUMAN
    Recommended name:
    Placenta-specific protein 4
    Protein Accession:
    Q8WY50

    Protein attributes for PLAC4 Gene

    Size:
    150 amino acids
    Molecular mass:
    16680 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PLAC4 Gene

Proteomics data for PLAC4 Gene at MOPED

Post-translational modifications for PLAC4 Gene

No Post-translational modifications

Other Protein References for PLAC4 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for PLAC4 Gene

Domains & Families for PLAC4 Gene

Protein Domains for PLAC4 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for PLAC4 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PLAC4: view

No data available for Gene Families and UniProtKB/Swiss-Prot for PLAC4 Gene

Function for PLAC4 Gene

Phenotypes for PLAC4 Gene

GenomeRNAi human phenotypes for PLAC4:
genes like me logo Genes that share phenotypes with PLAC4: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PLAC4 Gene

Localization for PLAC4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PLAC4 Gene

Pathways & Interactions for PLAC4 Gene

SuperPathways for PLAC4 Gene

No Data Available

Interacting Proteins for PLAC4 Gene

Gene Ontology (GO) - Biological Process for PLAC4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PLAC4 Gene

Drugs & Compounds for PLAC4 Gene

No Compound Related Data Available

Transcripts for PLAC4 Gene

mRNA/cDNA for PLAC4 Gene

Unigene Clusters for PLAC4 Gene

Placenta-specific 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PLAC4 Gene

No ASD Table

Relevant External Links for PLAC4 Gene

GeneLoc Exon Structure for
PLAC4
ECgene alternative splicing isoforms for
PLAC4

Expression for PLAC4 Gene

mRNA expression in normal human tissues for PLAC4 Gene

mRNA differential expression in normal tissues according to GTEx for PLAC4 Gene

This gene is overexpressed in Esophagus - Mucosa (x7.1) and Minor Salivary Gland (x5.7).

SOURCE GeneReport for Unigene cluster for PLAC4 Gene Hs.472492

mRNA Expression by UniProt/SwissProt for PLAC4 Gene

Q8WY50-PLAC4_HUMAN
Tissue specificity: Expressed in placental syncytiotrophoblast and choriocarcinoma cells.
genes like me logo Genes that share expression patterns with PLAC4: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for PLAC4 Gene

Orthologs for PLAC4 Gene

Evolution for PLAC4 Gene

ENSEMBL:
Gene Tree for PLAC4 (if available)
TreeFam:
Gene Tree for PLAC4 (if available)

No data available for Orthologs for PLAC4 Gene

Paralogs for PLAC4 Gene

(1) SIMAP similar genes for PLAC4 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with PLAC4: view

No data available for Paralogs for PLAC4 Gene

Variants for PLAC4 Gene

Structural Variations from Database of Genomic Variants (DGV) for PLAC4 Gene

Variant ID Type Subtype PubMed ID
nsv7347 OTHER Inversion 18451855

Relevant External Links for PLAC4 Gene

HapMap Linkage Disequilibrium report
PLAC4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for PLAC4 Gene

Disorders for PLAC4 Gene

Relevant External Links for PLAC4

Genetic Association Database (GAD)
PLAC4
Human Genome Epidemiology (HuGE) Navigator
PLAC4
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PLAC4

No disorders were found for PLAC4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PLAC4 Gene

Publications for PLAC4 Gene

  1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48 67
  2. Synergy of total PLAC4 RNA concentration and measurement of the RNA single-nucleotide polymorphism allelic ratio for the noninvasive prenatal detection of trisomy 21. (PMID: 19892844) Tsui N.B. … Lo Y.M. (Clin. Chem. 2010) 3 23
  3. PLAC4 is upregulated in severe early onset preeclampsia and upregulated with syncytialisation but not hypoxia. (PMID: 23312075) Tuohey L. … Kaitu'u-Lino T.J. (Placenta 2013) 3
  4. Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies. (PMID: 23903356) Hayes M.G. … Lowe W.L. (Diabetes 2013) 3
  5. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3

Products for PLAC4 Gene

Sources for PLAC4 Gene

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