Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



PLA2G2A Gene

protein-coding   GIFtS: 72
GCID: GC01M020301

Phospholipase A2, Group IIA (Platelets, Synovial Fluid)


(Previous symbols: PLA2B, PLA2L)
  See PLA2G2A-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Phospholipase A2, Group IIA (Platelets, Synovial Fluid)1 2     MOM12 5
PLA2B1 2 3 5     PLA22
PLA2L1 2 3 5     PLA2S2
Group IIA Phospholipase A22 3     PLAS12
Non-Pancreatic Secretory Phospholipase A22 3     Phospholipase A2, Membrane Associated2
Phosphatidylcholine 2-Acylhydrolase 2A2 3     sPLA22
NPS-PLA22 3     EC 3.1.1.43
GIIC SPLA22 3     RASF-A3

External Ids:    HGNC: 90311   Entrez Gene: 53202   Ensembl: ENSG000001882577   OMIM: 1724115   UniProtKB: P145553   
ORGUL members:         

Export aliases for PLA2G2A gene to outside databases

Previous GC identifers: GC01M019872 GC01M019337 GC01M019717 GC01M019771 GC01M020047 GC01M020174 GC01M018547


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for PLA2G2A Gene:
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse
family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene
product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low
molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl
ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in
the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants
with different 5' UTRs have been found for this gene.(provided by RefSeq, Sep 2009)

GeneCards Summary for PLA2G2A Gene:
PLA2G2A (phospholipase A2, group IIA (platelets, synovial fluid)) is a protein-coding gene. Diseases associated with PLA2G2A include small bowel adenocarcinoma, and acute chest syndrome. GO annotations related to this gene include phospholipase A2 activity and calcium ion binding. An important paralog of this gene is ENSG00000258417.

UniProtKB/Swiss-Prot: PA2GA_HUMAN, P14555
Function: Thought to participate in the regulation of the phospholipid metabolism in biomembranes including
eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in
3-sn-phosphoglycerides

summary for PLA2G2A Gene:
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic
molecules. PLA is subdivided into PLA1 which cleave phospholipids at the sn-1 ester bond and PLA2, which
cleave at the sn-2 bond. Their most common substrate is phosphatidylcholine, which generates
lysophosphatidylcholine and arachidonic acid. PLA is regulated by phosphorylation and by intracellular Ca2+
concentrations. Phospholipases are ubiquitously expressed and have diverse biological functions including
roles in inflammation, cell growth, signaling and death and maintenance of membrane phospholipids.

Gene Wiki entry for PLA2G2A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the PLA2G2A gene promoter:
         Nkx3-1   Nkx3-1 v4   Egr-1   Nkx3-1 v1   STAT5A   MEF-2A   Nkx3-1 v2   Chx10   Nkx3-1 v3   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): PLA2G2A promoter sequence
   Search Chromatin IP Primers for PLA2G2A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PLA2G2A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35   Ensembl cytogenetic band:  1p36.13   HGNC cytogenetic band: 1p35

PLA2G2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PLA2G2A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M020301:  view genomic region     (about GC identifiers)

Start:
20,301,924 bp from pter      End:
20,306,932 bp from pter
Size:
5,009 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: PA2GA_HUMAN, P14555 (See protein sequence)
Recommended Name: Phospholipase A2, membrane associated precursor  
Size: 144 amino acids; 16083 Da
Cofactor: Binds 1 calcium ion per subunit
Miscellaneous: Group II phospholipase A2 is found in many cells and also extracellularly. The membrane-bound and
secreted forms are identical and are encoded by a single gene
Selected PDB 3D structures from and Proteopedia for PLA2G2A (see all 17):
1AYP (3D)        1BBC (3D)        1DB4 (3D)        1DB5 (3D)        1DCY (3D)        1J1A (3D)    
Secondary accessions: A8K5I7 Q6DN24 Q6IBD9 Q9UCD2

Explore the universe of human proteins at neXtProt for PLA2G2A: NX_P14555

Explore proteomics data for PLA2G2A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PLA2G2A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_000291.1  NP_001155199.1  NP_001155200.1  NP_001155201.1  

    ENSEMBL proteins: 
     ENSP00000364252   ENSP00000383364  
    Reactome Protein details: P14555

    PLA2G2A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for PLA2G2A
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for PLA2G2A
    OriGene Protein Over-expression Lysate for PLA2G2A
    OriGene MassSpec for PLA2G2A
    OriGene Custom Protein Services for PLA2G2A
    GenScript Custom Purified and Recombinant Proteins Services for PLA2G2A
    Novus Biologicals PLA2G2A Proteins
    Novus Biologicals PLA2G2A Lysate
    Sino Biological Recombinant Protein for PLA2G2A
    Sino Biological Cell Lysate for PLA2G2A
    ProSpec Recombinant Protein for PLA2G2A
    Cloud-Clone Corp. Proteins for PLA2G2A

     
    Search eBioscience for Proteins for PLA2G2A 

    PLA2G2A Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of PLA2G2A
    R&D Systems Antibodies for PLA2G2A
    OriGene Antibodies for PLA2G2A
    OriGene Custom Antibody Services for PLA2G2A
    Novus Biologicals PLA2G2A Antibodies
    Abcam antibodies for PLA2G2A
    Cloud-Clone Corp. Antibodies for PLA2G2A
    Search ThermoFisher Antibodies for PLA2G2A
    LSBio Antibodies in human, mouse, rat for PLA2G2A

    PLA2G2A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PLA2G2A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PLA2G2A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PLA2G2A
    Cloud-Clone Corp. CLIAs for PLA2G2A
    Search eBioscience for ELISAs for PLA2G2A 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    IUPHAR Guide to PHARMACOLOGY protein family classification: sPLA2-2A
    Phospholipase A2

    3 InterPro protein domains:
     IPR016090 PLipase_A2_dom
     IPR001211 PLipase_A2
     IPR013090 PLipase_A2_AS

    Graphical View of Domain Structure for InterPro Entry P14555

    ProtoNet protein and cluster: P14555

    1 Blocks protein domain: IPB001211 Phospholipase A2

    UniProtKB/Swiss-Prot: PA2GA_HUMAN, P14555
    Similarity: Belongs to the phospholipase A2 family


    Find genes that share domains with PLA2G2A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PA2GA_HUMAN, P14555
    Function: Thought to participate in the regulation of the phospholipid metabolism in biomembranes including
    eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in
    3-sn-phosphoglycerides
    Catalytic activity: Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate

         Genatlas biochemistry entry for PLA2G2A:
    phospholipase A2,group IIA,Ca2+ dependent,non pancreatic,secreted,expressed in platelets synovial fluid,potent
    mediator of the inflammatory process,enhanced by inflammatory cytokines as well as lipolysaccharides in various
    cell types,elevated in numerous inflammatory diseases including sepsis,Crohn disease and pancreatitis,deleted in
    neuroblastoma,not involved in colorectal carcinoma,homolog to murine Mom1 (see also MOM1,TSG1C)

         Enzyme Number (IUBMB): EC 3.1.1.41

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004623phospholipase A2 activity TAS--
    GO:0005509calcium ion binding IEA--
    GO:0005543phospholipid binding IDA9032461
    GO:0047498calcium-dependent phospholipase A2 activity TAS9272153
         
    Find genes that share ontologies with PLA2G2A           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for PLA2G2A:
     Increased G1 DNA content  Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Pla2g2a):
     tumorigenesis 

    Find genes that share phenotypes with PLA2G2A           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PLA2G2A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PLA2G2A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PLA2G2A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PLA2G2A

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat PLA2G2A using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PLA2G2A
    SwitchGear 3'UTR luciferase reporter plasmidPLA2G2A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PLA2G2A
    Predesigned siRNA for gene silencing in human, mouse, rat PLA2G2A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PLA2G2A

    Clone
    Products:
         
    OriGene clones in human, mouse for PLA2G2A (see all 23)
    OriGene ORF clones in mouse, rat for PLA2G2A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): PLA2G2A (NM_000300)
    Sino Biological Human cDNA Clone for PLA2G2A
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PLA2G2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLA2G2A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for PLA2G2A
    Browse ESI BIO Cell Lines and PureStem Progenitors for PLA2G2A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLA2G2A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    PA2GA_HUMAN, P14555: Membrane; Peripheral membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum4
    extracellular4
    plasma membrane2
    cytosol1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IDA17069818
    GO:0005783endoplasmic reticulum IDA--
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0030141secretory granule IEA--

    Find genes that share ontologies with PLA2G2A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for PLA2G2A About   (see all 25)  
    See pathways by source

    SuperPathContained pathways About
    1Glycerophospholipid biosynthesis
    Glycerophospholipid biosynthesis0.64
    Synthesis of PA0.33
    Phospholipid metabolism0.64
    Acyl chain remodelling of PG0.00
    Glycerophospholipid metabolism0.62
    Acyl chain remodelling of PI0.00
    2Acyl chain remodelling of PC
    Acyl chain remodelling of PE0.85
    Ether lipid metabolism0.48
    Acyl chain remodelling of PC0.85
    Acyl chain remodelling of PS0.00
    3Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37
    Metabolic pathways0.38
    4phospholipases
    phospholipases0.34
    Anandamide biosynthesis and metabolism0.34
    5PEDF Induced Signaling
    MIF Mediated Glucocorticoid Regulation0.94
    all-trans-Retinoic Acid Signaling in Brain0.71
    MIF Regulation of Innate Immune Cells0.94
    Endothelin-1 Signaling Pathway0.46


    Find genes that share SuperPaths with PLA2G2A           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for PLA2G2A (see all 13)
        Chemokine Signaling
    MIF Regulation of Innate Immune Cells
    DHA Signaling
    Endothelin-1 Signaling Pathway
    Antioxidant Action of Vitamin-C

    2 GeneGo (Thomson Reuters) Pathways for PLA2G2A
        Anandamide biosynthesis and metabolism
    Immune response CD16 signaling in NK cells

    5 BioSystems Pathways for PLA2G2A
        MicroRNAs in cardiomyocyte hypertrophy
    Eicosanoid Synthesis
    Spinal Cord Injury
    Glypican 1 network
    phospholipases


    Selected Reactome Pathways for PLA2G2A (see all 6)
        Acyl chain remodelling of PE
    Acyl chain remodelling of PS
    Synthesis of PA
    Acyl chain remodelling of PC
    Acyl chain remodelling of PG

    2 PharmGKB Pathways for PLA2G2A
        Celecoxib Pathway, Pharmacodynamics
    Platelet Aggregation Inhibitor Pathway, Pharmacodynamics

    Selected Kegg Pathways  (Kegg details for PLA2G2A) (see all 10):
        Glycerophospholipid metabolism
    Ether lipid metabolism
    Arachidonic acid metabolism
    Linoleic acid metabolism
    alpha-Linolenic acid metabolism

        Pathway & Disease-focused RT2 Profiler PCR Array including PLA2G2A: 
              VEGF Signaling in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for PLA2G2A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PLA2G2A (P145552, 3 ENSP000003642524) via UniProtKB, MINT, STRING, and/or I2D (see all 117)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CEP70Q8NHQ12, 3, ENSP000002649824MINT-8266733 I2D: score=2 STRING: ENSP00000264982
    CRMP1Q141942, 3MINT-63475 I2D: score=3 
    CRELD2Q6UXH12, 3MINT-8266722 I2D: score=1 
    BAG6P463793I2D: score=1 
    ENSG00000096155P463793I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0006654phosphatidic acid biosynthetic process TAS--
    GO:0010744positive regulation of macrophage derived foam cell differentiation TAS18827909
    GO:0016042lipid catabolic process IEA--
    GO:0034374low-density lipoprotein particle remodeling TAS18827909

    Find genes that share ontologies with PLA2G2A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for PLA2G2A available from Tocris Bioscience    About this table
    CompoundAction CAS #
    FIPIPhospholipase D inhibitor[939055-18-2]
    m-3M3FBSPhospholipase C activator[200933-14-8]
    Edelfosine Selective PI-PLC inhibitor, also PAF receptor agonist [77286-66-9]
    U 73343Inactive analog of U 73122 (Cat. No. 1268)[142878-12-4]
    D609Selective PC-PLC inhibitor[83373-60-8]

    Selected HMDB Compounds for PLA2G2A (see all 2140)    About this table
    CompoundSynonyms CAS #PubMed Ids
    PC(O-16:0/18:2(9Z,12Z))1-hexadecyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine (see all 5)88542-95-412486725
    PE(O-16:1(1Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 15)--12486725
    PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 19)103597-60-012486725
    Alpha-Linolenic acid(9,12,15)-linolenate (see all 23)463-40-1--
    Arachidic acidArachate (see all 10)506-30-9--
    Arachidonic acid5,8,11,14-Eicosatetraenoic acid (see all 16)506-32-1--
    CalciumCa (see all 2)7440-70-2--
    Heptadecanoic acidHeptadecanoate (see all 16)506-12-7--
    Heptadecanoyl CoAHeptadecanoyl coenzyme A (see all 19)3546-17-6--
    Linoleic acid(9Z,12Z)-9,12-Octadecadienoate (see all 26)60-33-3--

    Selected DrugBank Compounds for PLA2G2A (see all 14)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    1,4-Butanediol-- 110-63-4target--17139284 17016423 10592235
    1-Benzyl-5-Methoxy-2-Methyl-1h-Indol-3-Yl)-Acetic Acid-- --target--17139284 17016423 10592235
    4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid-- --target--17139284 17016423 10592235
    DiclofenacDiclofenac Acid (see all 4)15307-86-5targetinhibitor9279965 15906762 16552142
    Elaidoylamide-- --target--17139284 17016423 10592235
    Ginkgo bilobaAdiantifolia (see all 13)--targetinhibitor10418340 10619176 16651744
    [3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid-- --target--17139284 17016423 10592235
    (S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid-- --target--17139284 17016423
    1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide-- --target--17139284 17016423
    6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid-- --target--17139284 17016423

    Selected Novoseek inferred chemical compound relationships for PLA2G2A gene (see all 112)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    arachidonic acid 89.3 431 8636097 (5), 12813050 (5), 10657662 (5), 8555268 (4) (see all 99)
    manoalide 86.5 23 8702436 (4), 8228253 (3), 9677277 (1), 10051149 (1) (see all 11)
    scalaradial 85.9 13 17691073 (3), 8228253 (3), 10353635 (1), 8688196 (1) (see all 5)
    ly311727 84.8 10 11934806 (2), 17069818 (1), 8764358 (1), 12829607 (1) (see all 7)
    p-bromophenacyl bromide 84.3 44 2402761 (3), 8820966 (1), 9506985 (1), 11090064 (1) (see all 25)
    aacocf3 83.7 31 8195210 (2), 11800413 (2), 12558054 (1), 15082220 (1) (see all 18)
    bromoenol lactone 79.3 21 15082220 (1), 15474031 (1), 15950537 (1), 17537804 (1) (see all 13)
    7,7-dimethyl-eicosadienoic acid 79.1 3 16645197 (1), 12688422 (1), 1906891 (1)
    mafp 77.8 16 11641267 (1), 10026244 (1), 12039969 (1), 17374479 (1) (see all 8)
    phospholipid 76.7 91 11159446 (3), 9154867 (2), 9180373 (2), 9692992 (2) (see all 68)



    Find genes that share compounds with PLA2G2A           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for PLA2G2A gene (4 alternative transcripts): 
    NM_000300.3  NM_001161727.1  NM_001161728.1  NM_001161729.1  

    Unigene Cluster for PLA2G2A:

    Phospholipase A2, group IIA (platelets, synovial fluid)
    Hs.466804  [show with all ESTs]
    Unigene Representative Sequence: BX366627
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000469162 ENST00000496748 ENST00000375111(uc001bcu.3 uc001bcv.3 uc010oda.2)
    ENST00000491964 ENST00000482011 ENST00000461140 ENST00000400520(uc010odb.2)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PLA2G2A using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PLA2G2A
    SwitchGear 3'UTR luciferase reporter plasmidPLA2G2A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PLA2G2A
    Predesigned siRNA for gene silencing in human, mouse, rat PLA2G2A
    Clone
    Products:
         
    OriGene clones in human, mouse for PLA2G2A (see all 23)
    OriGene ORF clones in mouse, rat for PLA2G2A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): PLA2G2A (NM_000300)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PLA2G2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLA2G2A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PLA2G2A
    OriGene qSTAR qPCR primer pairs in human, mouse for PLA2G2A
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PLA2G2A
      QuantiTect SYBR Green Assays in human, mouse, rat PLA2G2A
      QuantiFast Probe-based Assays in human, mouse, rat PLA2G2A

    Additional mRNA sequence: 

    AK291302.1 AY656695.1 AY656696.1 BC005919.1 CR456865.1 M22430.1 

    12 DOTS entries:

    DT.448973  DT.91875898  DT.100846638  DT.91740599  DT.100770687  DT.121358013  DT.91740607  DT.100028625 
    DT.95278396  DT.95278386  DT.97846892  DT.95278401 

    Selected AceView cDNA sequences (see all 273):

    CF527749 BM686160 CB132375 T29484 CR605782 CR596161 BQ182317 BX358510 
    CA389364 BU726008 BX334819 BQ650118 CN480150 BQ181347 BU734454 CR600125 
    NM_000300 BM705186 AA320357 T39452 CR593348 R53758 CR622866 CA427197 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for PLA2G2A (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f
    SP1:                          -                       -                                                                     
    SP2:                          -     -                 -                                                                     
    SP3:                          -     -     -     -     -                                                                     
    SP4:                                                                                                                        
    SP5:                                                                    -                                                   


    ECgene alternative splicing isoforms for PLA2G2A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    PLA2G2A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGAAAGCAT
    PLA2G2A Expression
    About this image


    PLA2G2A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Heart (Cardiovascular System)
             Atrioventricular Node
     
     Epithelial Cells
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Eye (Sensory Organs)
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Thyroid (Endocrine System)
     
     Colon (Gastrointestinal Tract)
    PLA2G2A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PLA2G2A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.466804
        Pathway & Disease-focused RT2 Profiler PCR Array including PLA2G2A: 
              VEGF Signaling in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for PLA2G2A
    OriGene qSTAR qPCR primer pairs in human, mouse for PLA2G2A
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PLA2G2A
    QuantiTect SYBR Green Assays in human, mouse, rat PLA2G2A
    QuantiFast Probe-based Assays in human, mouse, rat PLA2G2A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLA2G2A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for PLA2G2A gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pla2g2a5 phospholipase A2, group IIA (platelets, synovial fluid)   --   4 (70.57 cM) 138831860 
    chicken
    (Gallus gallus)
    Aves PLA2G2A1 phospholipase A2, group IIA (platelets, synovial fluid) 55.48(n)
    47.14(a)
      426748  NM_001277914.1  NP_001264843.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    52(a)
    1 → many
    AAWZ02041529(3693-5527)


    ENSEMBL Gene Tree for PLA2G2A (if available)
    TreeFam Gene Tree for PLA2G2A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for PLA2G2A gene
    ENSG000002584172  PLA2G2F2  PLA2G2E2  PLA2G1B2  PLA2G2D2  OC902  PLA2G102  PLA2G52  
    PLA2G2C2  
    9 SIMAP similar genes for PLA2G2A using alignment to 2 protein entries:     PA2GA_HUMAN (see all proteins):
    PLA2    PLA2G2D    PLA2G5    PLA2G2E    PLA2G2F    PLA2G1B
    PLA2G10    OC90    PLA2G2C

    Find genes that share paralogs with PLA2G2A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for PLA2G2A (see all 210)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs115731441,2
    C,F--18553053(-) ATTCT-/TACACC 4 -- us2k12Minor allele frequency- T:0.46NS NA 172
    rs718576651,2
    C--20305467(+) CAATG-/CACACAC 4 -- int10--------
    rs115731341,2
    C,F--20308693(-) GCTTAT/CTAAGG 3 -- us2k12Minor allele frequency- C:0.03NS WA 280
    rs1840533301,2
    --20511820(+) GCACCA/GGTGTT 4 -- ds50010--------
    rs1386984091,2
    --20511836(+) CATCTA/GGATGA 4 -- ds50010--------
    rs37672211,2
    C,F,A--20511999(+) CAATCA/CTTGCA 4 -- ds50017Minor allele frequency- C:0.30NS NA WA EA 532
    rs115731771,2
    C,F--20512029(-) TCCCAG/CCTGCT 4 -- ds50012Minor allele frequency- C:0.02NS CSA 170
    rs8760181,2
    C,F,A,H--20512145(+) TATACA/TTGATT 4 -- ut3135Minor allele frequency- T:0.20EA NA NS CSA WA 3620
    rs115731761,2
    C,F,H--20512158(-) AAAGCA/CATTAG 4 -- ut315Minor allele frequency- C:0.00NS EA 598
    rs115731751,2
    C,F,H--20512175(-) GGGGGT/CCTCTT 4 -- ut31 ese36Minor allele frequency- C:0.01NS EA WA 712

    HapMap Linkage Disequilibrium report for PLA2G2A (20301924 - 20306932 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for PLA2G2A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv871115CNV Gain21882294
    nsv527818CNV Gain19592680

    Human Gene Mutation Database (HGMD): PLA2G2A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PLA2G2A
    DNA2.0 Custom Variant and Variant Library Synthesis for PLA2G2A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 172411   
    OMIM disorders: 114500  
    8 diseases for PLA2G2A:    
    About MalaCards
    small bowel adenocarcinoma    acute chest syndrome    colorectal cancer    gas gangrene
    transient cerebral ischemia    surfactant dysfunction    krabbe disease    ischemia

    2 diseases from the University of Copenhagen DISEASES database for PLA2G2A:
    Acute chest syndrome     Gas gangrene

    Find genes that share disorders with PLA2G2A           About GenesLikeMe

    Selected Novoseek inferred disease relationships for PLA2G2A gene (see all 94)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    inflammation 58.2 78 9849315 (2), 15224635 (2), 17573441 (2), 9748759 (2) (see all 60)
    rheumatoid arthritis 36.7 25 1757123 (2), 1540785 (2), 8018333 (2), 19765281 (2) (see all 19)
    intestinal polyps 36.3 2 8640784 (1), 9458096 (1)
    necrosis 36.3 30 1477075 (1), 7684376 (1), 8596153 (1), 10090397 (1) (see all 29)
    atherosclerosis 34.9 20 10381280 (3), 15897607 (2), 20153800 (2), 17353016 (2) (see all 12)
    arthritis 32.6 10 2254899 (1), 2033260 (1), 11090064 (1), 10051149 (1) (see all 10)
    shock septic 31.3 12 7780685 (3), 1757123 (2), 9219902 (2), 8490995 (2) (see all 7)
    edema 31.3 22 8206646 (2), 1358548 (2), 8519280 (2), 11054123 (1) (see all 14)
    acute pancreatitis 30.7 26 9135530 (4), 1459357 (3), 8472353 (2), 10077051 (2) (see all 10)
    respiratory distress syndrome 28.5 6 11373495 (1), 8472353 (1), 18853138 (1), 11040450 (1) (see all 5)

    Genetic Association Database (GAD): PLA2G2A
    Human Genome Epidemiology (HuGE) Navigator: PLA2G2A (19 documents)

    Export disorders for PLA2G2A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for PLA2G2A gene, integrated from 10 sources (see all 833):
    (articles sorted by number of sources associating them with PLA2G2A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2-A resolution. (PubMed id 2062381)1, 2, 9 Wery J.-P.... Jones N.D. (Nature 1991)
    2. Allelic association analysis of phospholipase A2 genes with schizophrenia. (PubMed id 15318030)1, 4, 9 Junqueira R....Vallada H. (Psychiatr. Genet. 2004)
    3. Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study. (PubMed id 17545304)1, 4, 9 Wootton P.T....Talmud P.J. (Hum. Mol. Genet. 2007)
    4. Structures of free and inhibited human secretory phospholipase A2 from inflammatory exudate. (PubMed id 1948070)1, 2, 9 Scott D.L....Sigler P.B. (Science 1991)
    5. Role of polymorphic variants as genetic modulators of infection in neonatal sepsis. (PubMed id 20463618)1, 4 Abu-Maziad A....Murray J.C. (Pediatr. Res. 2010)
    6. Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178)1, 4 Segat L....Crovella S. (Vaccine 2010)
    7. Genetic susceptibility to distinct bladder cancer subphenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (Eur. Urol. 2010)
    8. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    9. Molecular and functional characterization of polymorphisms in the secreted phospholipase A2 group X gene: relevance to coronary artery disease. (PubMed id 19495570)1, 4 Gora S....Karabina S.A. (J. Mol. Med. 2009)
    10. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1, 4 Shen M....Lan Q. (Environ. Mol. Mutagen. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 5320 HGNC: 9031 AceView: PLA2G2A Ensembl:ENSG00000188257 euGenes: HUgn5320
    ECgene: PLA2G2A Kegg: 5320 H-InvDB: PLA2G2A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for PLA2G2A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for PLA2G2A Genetics and Cytogenetics in Oncology and Haematology
    NIEHS-SNPshttp://egp.gs.washington.edu/data/pla2g2a/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for PLA2G2A gene:
    Search GeneIP for patents involving PLA2G2A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     Browse Kits and Assays available from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of PLA2G2A
     Browse Small Molecules at EMD Millipore
     Browse Purified and Recombinant Proteins at EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Antibodies for PLA2G2A (PLA2G2A)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Recombinant/Natural Proteins for PLA2G2A (PLA2G2A)   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for PLA2G2A   OriGene RNAi products in human, mouse, rat for PLA2G2A  
     OriGene qPCR primer pairs and template standards for PLA2G2A   OriGene Protein Over-expression Lysate for PLA2G2A  
     OriGene MassSpec something-or-other for PLA2G2A   OriGene clones in human, mouse for PLA2G2A  
     OriGene qSTAR qPCR primer pairs in human, mouse for PLA2G2A   OriGene Purified Protein for PLA2G2A  
     OriGene ORF clones in mouse, rat for PLA2G2A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PLA2G2A   OriGene Custom Protein Services for PLA2G2A  

     
     
     Block miRNA regulation of human, mouse, rat PLA2G2A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PLA2G2A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PLA2G2A Predesigned siRNA for gene silencing in human, mouse, rat PLA2G2A
     QuantiFast Probe-based Assays in human, mouse, rat PLA2G2A QuantiTect SYBR Green Assays in human, mouse, rat PLA2G2A
     PCR Arrays including human, mouse, rat PLA2G2A Search Chromatin IP Primers for PLA2G2A
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PLA2G2A  GeneGlobe Interaction Network for PLA2G2A
     Regulatory tfbs in PLA2G2A promoter
     GenScript Custom Purified and Recombinant Proteins Services for PLA2G2A GenScript cDNA clones with any tag delivered in your preferred vector for PLA2G2A
     GenScript Custom Assay Services for PLA2G2A GenScript Custom overexpressing Cell Line Services for PLA2G2A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Tocris compounds for PLA2G2A
     Proteins for PLA2G2A
     Cell Lysates for PLA2G2A
     cDNA Clones for PLA2G2A
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     PLA2G2A antibodies
     PLA2G2A proteins
     PLA2G2A lysates
     Antibodies for PLA2G2A
     See all of Abcam's Antibodies, Kits and Proteins for PLA2G2A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for PLA2G2A
     Proteins for PLA2G2A
     Antibodies for PLA2G2A
     ELISAs for PLA2G2A
     CLIAs for PLA2G2A



     Browse ESI BIO Cell Lines and PureStem Progenitors for PLA2G2A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLA2G2A
     SwitchGear 3'UTR luciferase reporter plasmids for PLA2G2A
     SwitchGear Promoter luciferase reporter plasmids for PLA2G2A
     Search ThermoFisher Antibodies for PLA2G2A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLA2G2A
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PLA2G2A
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PLA2G2A
     LSBio Antibodies in human, mouse, rat for PLA2G2A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for PLA2G2A
      Search eBioscience for proteins for PLA2G2A
      Search eBioscience for elisas for PLA2G2A
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      PLA2G2A gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4