PLA2G12A Gene
protein-coding GIFtS: 56
GCID: GC04M110631
|
|
phospholipase A2, group XIIA(Previous names: phospholipase A2, group XII )
(Previous symbol: PLA2G12)
| |
Aliases
for PLA2G12A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Phospholipase A2, Group XIIA1 2 | | ROSSY2 5 | | PLA2G121 2 3 | | Phospholipase A2, Group XII1 | | Phosphatidylcholine 2-Acylhydrolase 12A2 3 | | Group XII Secreted Phospholipase A22 | | GXII SPLA22 3 | | Group XIIA Secreted Phospholipase A22 | | SPLA2-XII1 | | Group XIIA Secretory Phospholipase A22 | | GXII2 5 | | EC 3.1.1.43 |
Export aliases for PLA2G12A gene to outside databasesPrevious GC identifers: GC04M111093 GC04M110992 GC04M110854 GC04M106364 |
Summaries
for PLA2G12A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PLA2G12A:
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoidsand exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively lowspecific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 (PubMed11031251)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: PG12A_HUMAN, Q9BZM1Function: PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does notexhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine
 summary
for PLA2G12A: Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic
molecules. PLA is subdivided into PLA1 which cleave phospholipids at the sn-1 ester bond and PLA2, which
cleave at the sn-2 bond. Their most common substrate is phosphatidylcholine, which generates
lysophosphatidylcholine and arachidonic acid. PLA is regulated by phosphorylation and by intracellular Ca2+
concentrations. Phospholipases are ubiquitously expressed and have diverse biological functions including
roles in inflammation, cell growth, signaling and death and maintenance of membrane phospholipids.
Gene Wiki entry for PLA2G12A
|
Genomic Views
for PLA2G12A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PLA2G12A gene promoter:
USF1 ATF-2 FOXO3 Evi-1 C/EBPalpha FOXO3b POU2F1 USF-1 POU2F1a FOXO3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for PLA2G12A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PLA2G12A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q25 Ensembl cytogenetic band: 4q25 HGNC cytogenetic band: 4q25PLA2G12A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M110631: view genomic region
(about GC identifiers)
Start:
|
110,631,145 bp from pter |
End:
|
110,651,242 bp from pter |
Size:
|
20,098 bases |
Orientation:
|
minus strand |
|
Proteins
for PLA2G12A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PG12A_HUMAN, Q9BZM1 (See
protein sequence)Recommended Name: Group XIIA secretory phospholipase A2 precursor Size: 189 amino acids; 21067 Da
Cofactor: Binds 1 calcium ion per subunit (By similarity)
Subcellular location: Secreted. Cytoplasm
Mass spectrometry: Mass=18702.6; Mass_error=0.5; Method=MALDI; Range=22-189; Source=PubMed:11031251;
Secondary accessions: Q9BZ89Explore the universe of human proteins at neXtProt for PLA2G12A: NX_Q9BZM1
PLA2G12A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_110448.2
ENSEMBL proteins: ENSP00000243501 ENSP00000425274 ENSP00000424021 Reactome Protein details: Q9BZM1
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
PLA2G12A for ontologies About GeneDecksing
PLA2G12A Antibody Products:
Assay Products for PLA2G12A: |
Protein
Domains /
Families
for PLA2G12A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PLA2G12A for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BZM1ProtoNet protein and cluster: Q9BZM1 1 Blocks protein family: IPB010711 Group XII secretory phospholipase A2
UniProtKB/Swiss-Prot: PG12A_HUMAN, Q9BZM1Similarity: Belongs to the phospholipase A2 family |
Function
for PLA2G12A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PG12A_HUMAN, Q9BZM1Function: PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does notexhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamineCatalytic activity: Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylateEnzyme Number (IUBMB): EC 3.1.1.41
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PLA2G12A (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PLA2G12A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PLA2G12A (NM_030821) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PLA2G12A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLA2G12A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLA2G12A |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
PLA2G12A for ontologies About GeneDecksing
|
Pathways & Interactions
for PLA2G12A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/20 super-pathways (see all 20) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Acyl chain remodelling of PE | | | 2 | alpha-Linolenic acid metabolism | | | 3 | Glycerophospholipid biosynthesis | | | 4 | Metabolism | | | 5 | Immune response CD16 signaling in NK cells | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for PLA2G12A
5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for PLA2G12A (see all 7)
1  GeneGo (Thomson Reuters) Pathway for PLA2G12A
1  BioSystems Pathway for PLA2G12A
5/10 
Reactome Pathways for PLA2G12A (see all 10)
5/16 
Kegg Pathways (Kegg details for PLA2G12A) (see all 16):
PLA2G12A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PLA2G12A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/77 Interacting proteins for PLA2G12A (ENSP000002435014) via UniProtKB, MINT, STRING, and/or I2D (see all 77)About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006644 | phospholipid metabolic process |
TAS | -- | | GO:0006654 | phosphatidic acid biosynthetic process |
TAS | -- | | GO:0008150 | biological_process |
ND | -- | | GO:0016042 | lipid catabolic process |
IEA | -- | | GO:0036148 | phosphatidylglycerol acyl-chain remodeling |
TAS | -- |
PLA2G12A for ontologies About GeneDecksing
|
Drugs & Compounds
for PLA2G12A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for PLA2G12A available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| RHC 80267 | Diacylglycerol lipase inhibitor | [83654-05-1] | | AACOCF3 | Phospholipase A2 inhibitor | [149301-79-1] | | OBAA | Phospholipase A2 inhibitor | [221632-26-4] | | PACOCF3 | Phospholipase A2 inhibitor | [141022-99-3] |
10/2140 HMDB Compounds for PLA2G12A (see all 2140) About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| PC(O-16:0/18:2(9Z,12Z)) | 1-hexadecyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine (see all 5) | 88542-95-4 | 12486725 | | PE(O-16:1(1Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) | 1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 15) | -- | 12486725 | | PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z)) | 1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 19) | 103597-60-0 | 12486725 | | Alpha-Linolenic acid | (9,12,15)-linolenate (see all 23) | 463-40-1 | -- | | Arachidic acid | Arachate (see all 10) | 506-30-9 | -- | | Arachidonic acid | 5,8,11,14-Eicosatetraenoic acid (see all 16) | 506-32-1 | -- | | Calcium | Ca (see all 2) | 7440-70-2 | -- | | Heptadecanoic acid | Heptadecanoate (see all 16) | 506-12-7 | -- | | Heptadecanoyl CoA | Heptadecanoyl coenzyme A (see all 19) | 3546-17-6 | -- | | Linoleic acid | (9Z,12Z)-9,12-Octadecadienoate (see all 26) | 60-33-3 | -- |
Search CenterWatch for drugs/clinical trials and news about PLA2G12A / PG12A
|
Transcripts
for PLA2G12A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PLA2G12A gene: NM_030821.4 Unigene Cluster for PLA2G12A: Phospholipase A2, group XIIA Hs.389452 [show with all ESTs]Unigene Representative Sequence: NM_0308214 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000243501(uc003hzp.3 uc010img.3) ENST00000502283 ENST00000507961
ENST00000502772
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PLA2G12A (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PLA2G12A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PLA2G12A (NM_030821) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PLA2G12A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLA2G12A |
Additional cDNA sequence: AF306567.1 AF332892.1 AK075389.1 AK313081.1 AY359024.1 BC017218.2 13 DOTS entries: DT.446121 DT.97841910 DT.109599 DT.101983900 DT.410754 DT.95115200 DT.100767448 DT.99934299 DT.121269731 DT.100833473 DT.100707334 DT.101959848 DT.97820352 24/436 AceView cDNA sequences (see all 436): CR591422 BF061913 BX378996 AL708640 CA426336 BE464619 BM924043 N91912 BQ223375 CA951162 BC000305 AA649828 BM787437 AI095057 BG676262 CB132416 AW891114 BM714055 AU280336 CR616049 F11345 BM803084 BX092618 BE045840
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for PLA2G12A (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PLA2G12A
|
Expression
for PLA2G12A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PLA2G12A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACAAATGTCA
About this image
See PLA2G12A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PLA2G12A
SOURCE GeneReport for Unigene cluster: Hs.389452
UniProtKB/Swiss-Prot: PG12A_HUMAN, Q9BZM1Tissue specificity: Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas
SABiosciences Expression via Pathway-Focused PCR Arrays including PLA2G12A:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PLA2G12A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PLA2G12A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PLA2G12A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PLA2G12A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLA2G12A |
Orthologs
for PLA2G12A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PLA2G12A gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
PLA2G12A1 |
phospholipase A2, group XIIA |
76.37(n)
80.77(a) |
|
772082 XM_001235269.2 XP_001235270.2 |
lizard
(Anolis carolinensis) |
Reptilia |
PLA2G12A6 |
-- |
70(a) |
1 ↔ 1 |
5(144432713-144440613) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.319282 |
Xenopus laevis transcribed sequence with weak similarity more |
76.99(n) |
|
AW639634.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.202712 |
Danio rerio, clone IMAGE5602294, mRNA, partial cds |
73.82(n) |
|
BC046040.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
GXIVsPLA26 |
GXIVsPLA2 |
22(a) |
1 → many |
3L(15948196-15949565) |
ENSEMBL Gene Tree for PLA2G12A (if available)
TreeFam Gene Tree for PLA2G12A (if available) |
Paralogs
for PLA2G12A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PLA2G12A gene
- PLA2G12B2
1 SIMAP similar gene for PLA2G12A using alignment to 3 protein entries: PG12A_HUMAN (see all proteins):PLA2G12B
PLA2G12A for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for PLA2G12A
PGOHUM00000242902 PGOHUM00000248570 PGOHUM00000244721 PGOHUM00000245221
|
Genomic Variants
for PLA2G12A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PLA2G12A |
|
Disorders
/ Diseases
for PLA2G12A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PLA2G12A for disorders About GeneDecksing
OMIM gene information: 611652
OMIM disorders: --
5  diseases for PLA2G12A: About MalaCardsalcohol dependence toxoplasmosis alcoholism pancreatitis
neuronitis
Human Genome Epidemiology (HuGE) Navigator: PLA2G12A (5 documents)
Export disorders for PLA2G12A gene to outside databases
|
Publications
for PLA2G12A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PLA2G12A gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with PLA2G12A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and recombinant expression of a structurally novel human secreted phospholipase A2. (PubMed id 11031251)1, 2, 3 Gelb M.H.... Lambeau G. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII). (PubMed id 12522102)1, 2 Murakami M.... Kudo I. (2003)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1 Kalsi G....Riley B.P. (2010)
- Genetic variants near TIMP3 and high-density lipoprot ein-associated loci influence susceptibility to age-related macular degeneratio n. (PubMed id 20385819)1 Chen W....Swaroop A. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1 Hosgood H.D....Lan Q. (2009)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (2005)
|
External Searches for PLA2G12A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PLA2G12A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PLA2G12A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PLA2G12A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PLA2G12A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PLA2G12A gene:
Search GeneIP for patents involving PLA2G12A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for PLA2G12A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for PLA2G12A | | OriGene shRNA RFP for PLA2G12A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PLA2G12A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PLA2G12A | | | OriGene Protein Over-expression Lysate for PLA2G12A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PLA2G12A | | OriGene 3'-UTR Clone for PLA2G12A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PLA2G12A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PLA2G12A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PLA2G12A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PLA2G12A | | OriGene Custom Protein Services for PLA2G12A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PLA2G12A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PLA2G12A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PLA2G12A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PLA2G12A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PLA2G12A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PLA2G12A |
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 | | | PLA2G12A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PLA2G12A |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PLA2G12A |
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