External Ids for PKP3 Gene
Previous GeneCards Identifiers for PKP3 Gene
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
GeneCards Summary for PKP3 Gene
PKP3 (Plakophilin 3) is a Protein Coding gene. Among its related pathways are Developmental Biology. GO annotations related to this gene include binding and alpha-catenin binding. An important paralog of this gene is PKP2.
UniProtKB/Swiss-Prot for PKP3 Gene
May play a role in junctional plaques.