PKP1 Gene
protein-coding GIFtS: 57
GCID: GC01P201252
|
|
plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
| |
Aliases
for PKP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Plakophilin 1 (Ectodermal Dysplasia/Skin Fragility Syndrome)1 2 | | B6P1 2 3 | | Band 6 Protein2 3 | | Plakophilin-11 |
Export aliases for PKP1 gene to outside databasesPrevious GC identifers: GC01P198976 GC01P196710 GC01P197719 GC01P198540 GC01P197984 GC01P199519 GC01P172418 |
Summaries
for PKP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PKP1:
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins containnumerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins tointermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilizationduring desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragilitysyndrome. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul2010)
UniProtKB/Swiss-Prot: PKP1_HUMAN, Q13835Function: Seems to play a role in junctional plaques. Contributes to epidermal morphogenesis
Gene Wiki entry for PKP1
|
Genomic Views
for PKP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PKP1 gene promoter:
SRF GR NF-1 SRF (504 AA) GR-beta PPAR-gamma1 PPAR-gamma2 GR-alpha Zic3
Other transcription factors
Search SABiosciences Chromatin IP Primers for PKP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PKP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q32 Ensembl cytogenetic band: 1q32.1 HGNC cytogenetic band: 1q32PKP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P201252: view genomic region
(about GC identifiers)
Start:
|
201,252,580 bp from pter |
End:
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201,302,121 bp from pter |
Size:
|
49,542 bases |
Orientation:
|
plus strand |
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Proteins
for PKP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PKP1_HUMAN, Q13835 (See
protein sequence)Recommended Name: Plakophilin-1 Size: 747 amino acids; 82861 Da
Subcellular location: Isoform 1: Nucleus. Cell junction, desmosome
Subcellular location: Nucleus
1 PDB 3D structure from  and Proteopedia  for PKP1:1XM9 (3D)
Secondary accessions: O00645 Q14CA0 Q15152Alternative splicing: 2 isoforms: Q13835-1 Q13835-2 Explore the universe of human proteins at neXtProt for PKP1: NX_Q13835
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13835
PKP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_000290.2 NP_001005337.1
ENSEMBL proteins: ENSP00000356293 ENSP00000295597 ENSP00000263946 Reactome Protein details: Q13835
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
PKP1 for ontologies About GeneDecksing
PKP1 Antibody Products:
Assay Products for PKP1: |
Protein
Domains /
Families
for PKP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PKP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13835ProtoNet protein and cluster: Q13835 UniProtKB/Swiss-Prot: PKP1_HUMAN, Q13835Similarity: Belongs to the beta-catenin familySimilarity: Contains 9 ARM repeats |
Function
for PKP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PKP1_HUMAN, Q13835Function: Seems to play a role in junctional plaques. Contributes to epidermal morphogenesis Genatlas biochemistry entry for PKP1:plakophilin 1,essential plaque protein of desmosomes in stratified epithelia with desmosomal location,interacting withdesmogleins and desmocollins,involved in cutaneous cell-cell interaction and epidermal morphogenesis,homologous toDrosophila Armadillo segment polarity gene,enhancing lateral interaction between desmoplakines molecules
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PKP1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PKP1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for PKP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PKP1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKP1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
PKP1 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for PKP1:
|
Pathways & Interactions
for PKP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptotic cleavage of cellular proteins | | | 2 | Cytoskeleton remodeling Keratin filaments | | | 3 | Apoptotic cleavage of cell adhesion proteins | | | 4 | Ubiquitinated Orc1 is degraded by the proteasome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for PKP1
1  GeneGo (Thomson Reuters) Pathway for PKP1
4 
Reactome Pathways for PKP1
PKP1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PKP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/21 Interacting proteins for PKP1 (Q138353 ENSP000002639464) via UniProtKB, MINT, STRING, and/or I2D (see all 21)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
PKP1 for ontologies About GeneDecksing
|
Drugs & Compounds
for PKP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PKP1 for compounds About GeneDecksing
 Browse Tocris compounds for PKP1
2 Novoseek chemical compound relationships for PKP1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lipid |
0 |
1 |
8804921 (1) |
| calcium |
0 |
2 |
10880961 (1), 14987275 (1) |
Search CenterWatch for drugs/clinical trials and news about PKP1
|
Transcripts
for PKP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PKP1 gene (2 alternative transcripts): NM_000299.3 NM_001005337.2 Unigene Cluster for PKP1: Plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) Hs.497350 [show with all ESTs]Unigene Representative Sequence: NM_0002995 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000367324(uc001gwe.3 uc009wzm.3) ENST00000352845 ENST00000475988
ENST00000477817 ENST00000263946(uc001gwd.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PKP1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PKP1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): PKP1 (NM_001005337) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PKP1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PKP1 |
Additional cDNA sequence: AK123555.1 AK299473.1 AK315291.1 AK316131.1 BC040253.1 BC114571.1 X79293.1 Z34974.1 8 DOTS entries: DT.95375996 DT.95376002 DT.91687041 DT.121354190 DT.97825723 DT.121354196 DT.95311232 DT.95375998 24/144 AceView cDNA sequences (see all 144): BX505134 BG677173 AA010145 AI130749 CB127299 AL698788 CB127297 BM913960 BM702721 BG679653 BE673006 AW873049 AI373444 NM_000299 AI685459 BG675696 BG682295 BX101390 BM987411 BX390309 BF222370 BG743204 BF876654 AW873059
GeneLoc Exon Structure
|
Expression
for PKP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PKP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTGTAGAGG
About this image
See PKP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PKP1
SOURCE GeneReport for Unigene cluster: Hs.497350
UniProtKB/Swiss-Prot: PKP1_HUMAN, Q13835Tissue specificity: Isoform 2 is widely expressed. Isoform 1 is expressed in stratified squamous, complex, glandularduct and bladder epithelia
SABiosciences Expression via Pathway-Focused PCR Array including PKP1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PKP1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PKP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PKP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PKP1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKP1 |
Orthologs
for PKP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PKP1 gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
PKP11 |
plakophilin 1 (ectodermal dysplasia/skin fragility more |
73.16(n)
70.3(a) |
|
421158 XM_419240.3 XP_419240.3 |
lizard
(Anolis carolinensis) |
Reptilia |
PKP16 |
-- |
66(a) |
1 ↔ 1 |
4(131268854-131318455) |
zebrafish
(Danio rerio) |
Actinopterygii |
pkp1b1 |
plakophilin 1b |
51.48(n)
39.45(a) |
|
797838 XM_001338263.2 XP_001338299.2 |
fruit fly
(Drosophila melanogaster) |
Insecta |
p120ctn6 |
Adherens junction protein p120 |
19(a) |
1 → many |
2R(482798-496995) |
worm
(Caenorhabditis elegans) |
Secernentea |
jac-16 |
Juxtamembrane domain-associated catenin |
11(a) |
1 → many |
IV(15997633-16026815) |
ENSEMBL Gene Tree for PKP1 (if available)
TreeFam Gene Tree for PKP1 (if available) |
Paralogs
for PKP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PKP1 gene
- PKP22 CTNND12 PKP32 CTNND22 ARVCF2 PKP42
5 SIMAP similar genes for PKP1 using alignment to 2 protein entries: PKP1_HUMAN (see all proteins):CTNND2 ARVCF PKP2 CTNND1 PKP3
PKP1 for paralogs About GeneDecksing
|
Genomic Variants
for PKP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PKP1 (201252580 - 201302121 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PKP1: --
Human Gene Mutation Database (HGMD): PKP1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PKP1 |
|
Disorders
/ Diseases
for PKP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PKP1 for disorders About GeneDecksing
OMIM gene information: 601975
OMIM disorders: 604536
UniProtKB/Swiss-Prot: PKP1_HUMAN, Q13835
Defects in PKP1 are the cause of ectodermal dysplasia-skin fragility syndrome (EDSFS) [MIM:604536]; also knownas McGrath syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development oftwo or more ectodermal structures. EDSFS is characterized by features of both cutaneous fragility and congenitalectodermal dysplasia affecting abnormalities in other epithelia or tissues. Desmosomes in the skin are small andpoorly formed with widening of keratinocyte intercellular spaces and perturbed desmosome/keratin intermediate filamentinteractions
20/23  diseases for PKP1 (see all 23): About MalaCardsectodermal dysplasia/skin fragility syndrome ectodermal dysplasia hereditary mucoepithelial dysplasia hypohidrotic ectodermal dysplasia
retinol binding protein palmoplantar keratosis epidermolysis bullosa hypohidrosis
ewing's family of tumors keratosis panic disorder squamous cell carcinoma
liposarcoma vaginitis prostate adenocarcinoma hepatocellular carcinoma
esophageal cancer esophagitis carcinoma lung cancer
10 Novoseek disease relationships for PKP1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ectodermal dysplasia |
80.9 |
10 |
15086548 (2), 11180229 (2), 12839569 (1), 16632867 (1) (see all 6) |
| nail dystrophy |
80 |
1 |
10635620 (1) |
| skin erosion |
77.9 |
1 |
19945625 (1) |
| hnscc |
35.7 |
1 |
17668353 (1) |
| carcinoma squamous cell |
33.2 |
6 |
17668353 (4), 17593084 (1) |
| dysplasia |
29.9 |
7 |
11994137 (2), 10379701 (1), 16445790 (1), 12840072 (1) (see all 5) |
| cardiomyopathy |
27.7 |
2 |
19016709 (1) |
| metastasis |
0 |
2 |
12827610 (2) |
| tumors |
0 |
15 |
12827610 (3), 14744087 (1), 17668353 (1), 20348237 (1) (see all 5) |
| carcinoma |
0 |
1 |
8922383 (1) |
Genatlas disease: PKP1 cutaneous fragility and congenital ectodermal dysplasia affecting skin,hair and nails
Human Genome Epidemiology (HuGE) Navigator: PKP1 (7 documents)
Export disorders for PKP1 gene to outside databases
|
Publications
for PKP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PKP1 gene, integrated from 9 sources (see all 90):
(articles sorted by number of sources associating them with PKP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Structure of the armadillo repeat domain of plakophilin 1. (PubMed id 15663951)1, 2, 9 Choi H.-J. and Weis W.I. (2005)
- Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome. (PubMed id 9326952)1, 2, 9 McGrath J.A.... Eady R.A.J. (1997)
- The plakophilin 1 (PKP1) and plakoglobin (JUP) genes map to human chromosomes 1q and 17, respectively. (PubMed id 9272178)1, 3, 9 Cowley C.M....Buxton R.S. (1997)
- Plakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components. (PubMed id 9369526)1, 2, 9 Schmidt A....Franke W.W. (1997)
- Band 6 protein, a major constituent of desmosomes from stratified epithelia, is a novel member of the armadillo multigene family. (PubMed id 7527055)1, 2, 9 Hatzfeld M.... Weber K. (1994)
- Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability. (PubMed id 12840072)1, 9 South A.P....McGrath J.A. (2003)
- Physical characterization of plakophilin 1 reconstituted with and without zinc. (PubMed id 10880961)1, 9 Hofmann I....Langowski J. (2000)
- Ectodermal dysplasia-skin fragility syndrome. (PubMed id 19945625)1, 9 McGrath J.A. and Mellerio J.E. (2010)
- Decreased plakophilin-1 expression promotes increased motility in head and neck squamous cell carcinoma cells. (PubMed id 17668353)1, 9 Sobolik-Delmaire T....Wahl J.K. (2007)
- Carboxyl terminus of Plakophilin-1 recruits it to plasma membrane, whereas amino terminus recruits desmoplakin and promotes desmosome assembly. (PubMed id 16632867)1, 9 Sobolik-Delmaire T....Wahl J.K. (2006)
|
External Searches for PKP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PKP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PKP1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PKP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for PKP1 gene:
Search GeneIP for patents involving PKP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PKP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PKP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PKP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PKP1 | | | OriGene Protein Over-expression Lysate for PKP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PKP1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PKP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PKP1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PKP1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PKP1 | | OriGene Custom Protein Services for PKP1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PKP1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PKP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PKP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PKP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PKP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PKP1 |
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| | | | Search Tocris compounds for PKP1 |
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 | | | PKP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKP1 |
|  |  |  | | | | ThermoFisher Antibody for PKP1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PKP1 |
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