PKN3 Gene
protein-coding GIFtS : 57
GCID: GC09 P131464
protein kinase N3
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Aliasesfor PKN3 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Protein Kinase N3 1 2 RP11-545E17.12 Protein Kinase PKN-Beta2 3 Serine/Threonine-Protein Kinase N32 Protein-Kinase C-Related Kinase 32 3 PKNBETA3 EC 2.7.11.133 8 EC 2.7.118 PKNbeta1
Export aliases for PKN3 gene to outside databases Previous GC identifers: GC09P126841 GC09P128544 GC09P130504 GC09P101074
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Summariesfor PKN3 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: PKN3_HUMAN, Q6P5Z2 Function : Contributes to invasiveness in malignant prostate cancerGene Wiki entry for PKN3
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Viewsfor PKN3 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000009.11 NC_018920.1 NT_008470.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the PKN3 gene promoter: Max Elk-1 Meis-1a IRF-1 Meis-1b Meis-1 c-Ets-1 c-Myc Other transcription factors Search SABiosciences Chromatin IP Primers for PKN3 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat PKN3
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 9q34.11 Ensembl cytogenetic band: 9q34.11 HGNC cytogenetic band: 9q34.13 PKN3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 9 GeneLoc Exon Structure
GeneLoc location for GC09P131464: view genomic region
(about GC identifiers )
Start:
131,464,802 bp from pter
End:
131,483,199 bp from pter
Size:
18,398 bases
Orientation:
plus strand
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Proteinsfor PKN3 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: PKN3_HUMAN, Q6P5Z2 (See
protein sequence )Recommended Name: Serine/threonine-protein kinase N3 Size : 889 amino acids; 99421 Da
Subcellular location : Nucleus. Cytoplasm, perinuclear region. Note=Nuclear and perinuclear Golgi region
Secondary accessions : Q9UM03Explore the universe of human proteins at neXtProt for PKN3: NX_Q6P5Z2 Post-translational modifications:
Autophosphorylated1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q6P5Z2 4/14 DME Specific Peptides for PKN3 (Q6P5Z2 ) (see all 14 )PKN3 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_037487.2 ENSEMBL proteins: ENSP00000291906 Human Recombinant Protein Products: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
PKN3 for ontologies About GeneDecksing PKN3 Antibody Products: Assay Products for PKN3:
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Protein
Domains / Familiesfor PKN3 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
PKN3 for domains About GeneDecksing 5/10 InterPro domains/families (see all 10 ):
Graphical View of Domain Structure for InterPro Entry Q6P5Z2 ProtoNet protein and cluster: Q6P5Z2
4 Blocks protein families : IPB000008 C2 domain IPB000861 PKN/rhophilin/rhotekin rho-binding repeat IPB000961 Protein kinase C-terminal domain IPB011072 Protein kinase PKN/PRK1 UniProtKB/Swiss-Prot: PKN3_HUMAN, Q6P5Z2 Domain : The C1 domain does not bind the diacylglycerol (DAG)Similarity : Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamilySimilarity : Contains 1 AGC-kinase C-terminal domainSimilarity : Contains 1 protein kinase domainSimilarity : Contains 3 REM (Hr1) repeats
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Functionfor PKN3 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: PKN3_HUMAN, Q6P5Z2 Function : Contributes to invasiveness in malignant prostate cancerCatalytic activity : ATP + a protein = ADP + a phosphoproteinEnzyme regulation : Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need tobe phosphorylated for its full activation (By similarity) Enzyme Numbers (IUBMB): EC 2.7.11.13 1 2 EC 2.7.11 2
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for PKN3 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for PKN3OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: PKN3 (NM_013355 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PKN3 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat PKN3
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKN3
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view) : About this table
PKN3 for ontologies About GeneDecksing 5 GenomeRNAi human phenotypes for PKN3 :
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Pathways & Interactionsfor PKN3 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PKN3 STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)5 Interacting proteins for PKN3 (Q6P5Z2 1 , 2 , 3 ENSP00000291906 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 3 biological process terms (GO ID links to tree view) : About this table
PKN3 for ontologies About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Drugs & Compoundsfor PKN3 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for PKN3 2 HMDB Compounds for PKN3 About this table Search CenterWatch for drugs/clinical trials and news about PKN3
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Transcriptsfor PKN3 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for PKN3 gene: NM_013355.3 Unigene Cluster for PKN3:
Protein kinase N3 Hs.300485 [show with all ESTs ] Unigene Representative Sequence: NM_013355 3 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000291906 (uc004bvw.3 uc010myh.3 uc022bom.1 ) ENST00000483521 ENST00000485301 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for PKN3 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for PKN3OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: PKN3 (NM_013355 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PKN3 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat PKN3
Additional cDNA sequence: AB019692.1 BC023327.1 BC032794.1 BC041581.1 BC062558.1
5 DOTS entries : DT.99941669 DT.100679114
DT.100791012 DT.91965131 DT.100791008 24/114 AceView cDNA sequences (see all 114 ):
AW245135 AW247208 BQ637451 BX365586 BC062558 BX362740 BC041581 CR614288 BQ718905 BU858997 AI741644 NM_013355 AI816759 BE964632 BC023327 BX112091 AW247261 AI813418 AW247872 AW452912 CB987960 AW028806 BG825922 BF512194 GeneLoc Exon Structure 5 Alternative Splicing Database (ASD) splice patterns (SP) for PKN3 About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 SP1 :                                                     SP2 :                                     -                 SP3 :                                                     SP4 :   -                                                   SP5 :                                                    
ECgene alternative splicing isoforms for PKN3
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Expression for PKN3 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section PKN3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GGGCCACTGT
About this image PKN3 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table Stem Cell Differentiation: 1 LifeMap Cell Name Category Definitive endoderm-like cells (A scalable, suspensi... )Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See PKN3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for PKN3 SOURCE GeneReport for Unigene cluster: Hs.300485 UniProtKB/Swiss-Prot: PKN3_HUMAN, Q6P5Z2 Tissue specificity : Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues SABiosciences Custom PCR Arrays for PKN3 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for PKN3Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat PKN3 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat PKN3 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat PKN3 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKN3
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Orthologsfor PKN3 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for PKN3 gene from 4/22 species (see all 22 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
PKN31
protein kinase N3
61.57(n) 62.51(a)
 
417209 XM_003642279.1 XP_003642327.1
zebrafish (Danio rerio)
Actinopterygii
pkn36
protein kinase N3
49(a)
1 ↔ 1
5(33468091-33494960)
fruit fly (Drosophila melanogaster)
Insecta
Pkn6
Protein kinase related to protein kinase N
28(a)
1 → many
2R(5139815-5172602)
worm (Caenorhabditis elegans)
Secernentea
pkn-16
--
27(a)
1 → many
X(10397183-10402516)
ENSEMBL Gene Tree for PKN3 (if available)TreeFam Gene Tree for PKN3 (if available)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Paralogsfor PKN3 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for PKN3 gene PRKCQ 2 PRKCH 2 PRKCB 2 PRKCI 2 PRKCE 2 PKN1 2 PRKCA 2 PRKCD 2 PRKCZ 2 PRKCG 2 PKN2 2 18/35 SIMAP similar genes for PKN3 using alignment to 2 protein entries: PKN3_HUMAN (see all proteins )
(see all similar genes ):KIN27 AKT1 PKN1 AKT3 MARK4 PRKACA PRKCD PRKACB PKN2 AKT2 PRKACG PRKCZ PRKCH PRKCI RPS6KA3 PRKCG RPS6KB1 PRKX
PKN3 for paralogs About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Variantsfor PKN3 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 9 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for PKN3 (131464802 - 131483199 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for PKN3 1 CNV : 6716 Human Gene Mutation Database (HGMD) : PKN3 SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing PKN3
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Disorders
/ Diseasesfor PKN3 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
PKN3 for disorders About GeneDecksing
OMIM gene information: 610714
OMIM disorders : --2 diseases for PKN3 : About MalaCards prostate cancer prostatitis Export disorders for PKN3 gene to outside databases
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Publicationsfor PKN3 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for PKN3 gene, integrated from 9 sources (see all 17 ): (articles sorted by number of sources associating them with PKN3) Utopia : connect your pdf to the dynamic world of online information
Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha. (PubMed id 10441506) 1 , 2 , 3, 9 Oishi K.... Ono Y. (1999) DNA sequence and analysis of human chromosome 9. (PubMed id 15164053) 1 , 2 Humphray S.J.... Dunham I. (2004) PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase. (PubMed id 15282551) 1 , 2 Leenders F.... Klippel A. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) PKN regulates phospholipase D1 through direct interaction. (PubMed id 11259428) 1 , 9 Oishi K....Ono Y. (2001) A census of human soluble protein complexes. (PubMed id 22939629) 1 Havugimana P.C....Emili A. (2012) Regulatory domain selectivity in the cell-type specific PKN- dependence of cell migration. (PubMed id 21754995) 1 Lachmann S.... Parker P.J. (2011) Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572) 1 Lee K.A....Doedens J.R. (2011) Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048) 1 Danielsen J.M....Nielsen M.L. (2011) Large-scale proteomics analysis of the human kinome. (PubMed id 19369195) 2 Oppermann F.S.... Daub H. (2009)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
External Searches for PKN3 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genome Databases showing PKN3 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Other Databases showing PKN3 gene
(According to HUGE )
About This Section --
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Specialized Databases showing PKN3 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for PKN3 Pharmacogenomics, SNPs, Pathways
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
About This Section Patent Information for PKN3 gene: Search GeneIP for patents involving PKN3 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Productsfor PKN3 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for PKN3 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for PKN3 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for PKN3 OriGene Protein Over-expression Lysate for PKN3 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for PKN3 OriGene 3'-UTR Clone for PKN3 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for PKN3 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for PKN3 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for PKN3 OriGene Custom Protein Services for PKN3 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PKN3 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing PKN3 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat PKN3 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat PKN3 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat PKN3 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat PKN3
Search Tocris compounds for PKN3
PKN3 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKN3
ThermoFisher Antibodies for PKN3
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat PKN3
Jump to Section...
Aliases for PKN3
Databases for PKN3
Disorders / Diseases for PKN3
Domains / Families for PKN3
Drugs / Compounds for PKN3
Expression for PKN3
Function for PKN3
Genomic Views for PKN3
Intellectual Property for PKN3
Orthologs for PKN3
Paralogs for PKN3
Pathways / Interactions for PKN3
Products for PKN3
Proteins for PKN3
Publications for PKN3
Search Box for PKN3
Summaries for PKN3
Transcripts for PKN3
Variants for PKN3
TOP
BOTTOM