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Aliases for PKN2 Gene

Aliases for PKN2 Gene

  • Protein Kinase N2 2 3 5
  • Protein Kinase C-Like 2 2 3 4
  • Cardiolipin-Activated Protein Kinase Pak2 2 3
  • Protein-Kinase C-Related Kinase 2 3 4
  • EC 2.7.11.13 4 61
  • PKN Gamma 3 4
  • PRKCL2 3 4
  • PRK2 3 4
  • Serine/Threonine-Protein Kinase N2 3
  • EC 2.7.11 61
  • PRO2042 3
  • PAK-2 3
  • STK7 3
  • PAK2 3

External Ids for PKN2 Gene

Previous HGNC Symbols for PKN2 Gene

  • PRKCL2

Previous GeneCards Identifiers for PKN2 Gene

  • GC01P088862
  • GC01P089149
  • GC01P087267

Summaries for PKN2 Gene

GeneCards Summary for PKN2 Gene

PKN2 (Protein Kinase N2) is a Protein Coding gene. Among its related pathways are Salmonella infection (KEGG) and Ca, cAMP and Lipid Signaling. GO annotations related to this gene include poly(A) RNA binding and protein kinase activity. An important paralog of this gene is PKN1.

UniProtKB/Swiss-Prot for PKN2 Gene

  • PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF). Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.

Gene Wiki entry for PKN2 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PKN2 Gene

Genomics for PKN2 Gene

Regulatory Elements for PKN2 Gene

Enhancers for PKN2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F089309 1.3 FANTOM5 Ensembl ENCODE 5.2 +626.7 626722 2.6 STAT1 MTA2 ZBTB2 HLF MAFG JUNB YY1 ZNF316 GATA2 ATF3 GBP1 GBP5 GBP4 GBP2 GTF2B PKN2 GBP3 LOC101927975 LRRC8C ENSG00000233235
GH01F088611 0.6 ENCODE 6.1 -71.5 -71477 2.3 OSR2 JUND JUN SCRT2 FOS SP7 TCF7L2 KYAT3 PKN2 LOC105378838 RPL36AP10
GH01F087928 0.5 ENCODE 5.9 -755.3 -755339 0.7 ZNF146 ATF3 HNF4G RAD21 PKN2 ENSG00000224235 LOC101927871
GH01F088889 1.5 FANTOM5 ENCODE 1.2 +207.4 207393 4.0 HDGF PKNOX1 MLX CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 ZNF2 YY1 KYAT3 PTGES3P1 RBMXL1 PKN2 GTF2B GC01M088841
GH01F088873 0.6 FANTOM5 Ensembl 1.9 +190.0 190008 0.8 PKN2 GTF2B GC01M088841
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PKN2 on UCSC Golden Path with GeneCards custom track

Promoters for PKN2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000540321 807 4401 HDGF PKNOX1 ARNT WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2

Genomic Location for PKN2 Gene

Chromosome:
1
Start:
88,684,193 bp from pter
End:
88,836,255 bp from pter
Size:
152,063 bases
Orientation:
Plus strand

Genomic View for PKN2 Gene

Genes around PKN2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PKN2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PKN2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PKN2 Gene

Proteins for PKN2 Gene

  • Protein details for PKN2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q16513-PKN2_HUMAN
    Recommended name:
    Serine/threonine-protein kinase N2
    Protein Accession:
    Q16513
    Secondary Accessions:
    • B4DQ21
    • B4DTP5
    • B4DVG1
    • D3DT24
    • Q08AF4
    • Q9H1W4

    Protein attributes for PKN2 Gene

    Size:
    984 amino acids
    Molecular mass:
    112035 Da
    Quaternary structure:
    • Interacts (via the REM repeats) with RHOA (GTP-bound form preferentially). Interacts (via the REM repeats) with RAC1 (GTP-bound form preferentially). Interacts with NCK1 (via SH3 domains). Interacts with CD44 (By similarity). Interacts with RHOA (GTP-bound form preferentially) and RAC1 (GTP-bound form preferentially); the interactions induce its autophosphorylation. Interacts (via C-terminal kinase domain) with PDPK1; the interaction stimulates PDPK1 kinase activity. Interacts with MAP3K2; the interaction activates PRK2 kinase activity in a MAP3K2-independent kinase activity. Interacts (via C-terminal domain) with AKT1; the interaction occurs with the C-terminal cleavage product of PRK2 in apoptotic cells. Interacts (via C-terminus) with PTPN13 (via PDZ 3 domain). Interacts with HCV NS5B (via N-terminal finger domain). Interacts with NCK1, NCK2 and RHOC.

    Three dimensional structures from OCA and Proteopedia for PKN2 Gene

    Alternative splice isoforms for PKN2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PKN2 Gene

Selected DME Specific Peptides for PKN2 Gene

Q16513:
  • ELKVKQGAENM
  • ESSQKLDLL
  • ACVVLGLQ
  • LQDSKTKI
  • AVAEGAKNV
  • TSTFCGTPEF
  • EFTSEAP
  • RAVDWWGLGV
  • LEDFLDN
  • AVLGRGHFGKVLL
  • LGVLIYEM
  • PVIERRP
  • FAIKALKK
  • YRDLKLDN
  • EELRHHF
  • YSTLSKPA
  • DFGLCKE
  • SNGSSKD
  • RDLKLDN

Post-translational modifications for PKN2 Gene

  • Activated by limited proteolysis with trypsin (By similarity). Proteolytically cleaved by caspase-3 during the induction of apoptotic cell death.
  • Autophosphorylated. Phosphorylated during mitosis.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for PKN2 (PKN2)

Domains & Families for PKN2 Gene

Graphical View of Domain Structure for InterPro Entry

Q16513

UniProtKB/Swiss-Prot:

PKN2_HUMAN :
  • The N-terminal regioninterferes with the interaction between AKT1 and the C-terminal regionof PKN2.
  • Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
  • Contains 3 REM (Hr1) repeats.
Domain:
  • The N-terminal regioninterferes with the interaction between AKT1 and the C-terminal regionof PKN2.
  • The C1 domain does not bind the diacylglycerol (DAG).
  • The apoptotic C-terminal cleavage product inhibits EGF-induced kinase activity of AKT1 phosphorylation at Thr-308 and Ser-473 sites, PDPK1 autophosphorylation and kinases PRKCD and PRKCZ phosphorylations.
  • Contains 1 AGC-kinase C-terminal domain.
  • Contains 1 C2 domain.
  • Contains 1 protein kinase domain.
Family:
  • Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Similarity:
  • Contains 3 REM (Hr1) repeats.
genes like me logo Genes that share domains with PKN2: view

Function for PKN2 Gene

Molecular function for PKN2 Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=15.83 uM for HDAC5 {ECO:0000269 PubMed:20188095};
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + a protein = ADP + a phosphoprotein.
UniProtKB/Swiss-Prot EnzymeRegulation:
Kinase activity is activated upon binding to GTP-bound Rhoa/Rac1 GTPases. Activated by caspase-3 (CASP3) cleavage during apoptosis. Activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Two specific sites, Thr-816 (activation loop of the kinase domain) and Thr-958 (turn motif), need to be phosphorylated for its full activation.
UniProtKB/Swiss-Prot Function:
PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF). Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.
UniProtKB/Swiss-Prot Induction:
Up-regulated during keratinocyte differentiation.

Enzyme Numbers (IUBMB) for PKN2 Gene

Gene Ontology (GO) - Molecular Function for PKN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity TAS 7851406
GO:0004674 protein serine/threonine kinase activity IDA 20188095
GO:0004697 protein kinase C activity IEA --
GO:0005515 protein binding IPI 10026169
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with PKN2: view
genes like me logo Genes that share phenotypes with PKN2: view

Animal Model Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for PKN2

Flow Cytometry Products

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PKN2 Gene

Localization for PKN2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PKN2 Gene

Cytoplasm. Nucleus. Membrane. Cell projection, lamellipodium. Cytoplasm, cytoskeleton. Cleavage furrow. Midbody. Cell junction. Note=Colocalizes with PTPN13 in lamellipodia-like structures, regions of large actin turnover. Accumulates during telophase at the cleavage furrow and concentrates finally around the midbody in cytokinesis. Recruited to nascent cell-cell contacts at the apical surface of cells. In the course of viral infection, colocalizes with HCV NS5B at perinuclear region in the cytoplasm. {ECO:0000269 PubMed:11356191, ECO:0000269 PubMed:17332740}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PKN2 gene
Compartment Confidence
nucleus 5
cytosol 5
cytoskeleton 4
plasma membrane 2

Gene Ontology (GO) - Cellular Components for PKN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 11356191
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA,IDA 17332740
GO:0005813 centrosome IDA --
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with PKN2: view

Pathways & Interactions for PKN2 Gene

genes like me logo Genes that share pathways with PKN2: view

Pathways by source for PKN2 Gene

2 Cell Signaling Technology pathways for PKN2 Gene
1 BioSystems pathway for PKN2 Gene

SIGNOR curated interactions for PKN2 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for PKN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006468 protein phosphorylation IDA,TAS 17332740
GO:0006915 apoptotic process IEA --
GO:0007049 cell cycle IEA --
genes like me logo Genes that share ontologies with PKN2: view

Drugs & Compounds for PKN2 Gene

(5) Drugs for PKN2 Gene - From: ApexBio, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ingenol Mebutate Approved Pharma 0
Adenosine triphosphate Approved Nutra 0
[Ser25] Protein Kinase C (19-31) Pharma PKC substrate 0
sophoretin Pharma inhibitor Kinase Inhibitors 0

(1) Additional Compounds for PKN2 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0

(1) ApexBio Compounds for PKN2 Gene

Compound Action Cas Number
[Ser25] Protein Kinase C (19-31) PKC substrate 136795-05-6
genes like me logo Genes that share compounds with PKN2: view

Transcripts for PKN2 Gene

Unigene Clusters for PKN2 Gene

Protein kinase N2:
Representative Sequences:

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for PKN2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PKN2 Gene

No ASD Table

Relevant External Links for PKN2 Gene

GeneLoc Exon Structure for
PKN2
ECgene alternative splicing isoforms for
PKN2

Expression for PKN2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PKN2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for PKN2 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (22.3) and Lung (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PKN2 Gene



Protein tissue co-expression partners for PKN2 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PKN2 Gene:

PKN2

SOURCE GeneReport for Unigene cluster for PKN2 Gene:

Hs.440833

mRNA Expression by UniProt/SwissProt for PKN2 Gene:

Q16513-PKN2_HUMAN
Tissue specificity: Ubiquitous. Expressed in numerous tumor cell lines, especially in bladder tumor cells.
genes like me logo Genes that share expression patterns with PKN2: view

Primer Products

No data available for mRNA differential expression in normal tissues for PKN2 Gene

Orthologs for PKN2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for PKN2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PKN2 34 35
  • 99.76 (n)
dog
(Canis familiaris)
Mammalia PKN2 34 35
  • 94.97 (n)
cow
(Bos Taurus)
Mammalia PKN2 34 35
  • 94.8 (n)
oppossum
(Monodelphis domestica)
Mammalia PKN2 35
  • 92 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Pkn2 34
  • 90.71 (n)
mouse
(Mus musculus)
Mammalia Pkn2 34 16 35
  • 90.4 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia PKN2 35
  • 87 (a)
OneToOne
chicken
(Gallus gallus)
Aves PKN2 34 35
  • 84.37 (n)
lizard
(Anolis carolinensis)
Reptilia PKN2 35
  • 88 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia pkn2 34
  • 77.88 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.21437 34
zebrafish
(Danio rerio)
Actinopterygii PKN2 (2 of 2) 35
  • 76 (a)
OneToMany
pkn2 34 35
  • 70.11 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007587 34
  • 56.54 (n)
fruit fly
(Drosophila melanogaster)
Insecta Pkn 34 35
  • 56.21 (n)
worm
(Caenorhabditis elegans)
Secernentea pkn-1 34 35
  • 49.44 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PKC1 35
  • 25 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 44 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.7005 34
Species where no ortholog for PKN2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PKN2 Gene

ENSEMBL:
Gene Tree for PKN2 (if available)
TreeFam:
Gene Tree for PKN2 (if available)

Paralogs for PKN2 Gene

Variants for PKN2 Gene

Sequence variations from dbSNP and Humsavar for PKN2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10158435 -- 88,820,076(+) ccatg(A/G)cacgt intron-variant
rs1018571 -- 88,832,304(-) GGAAA(A/G)ACAGA intron-variant
rs10489885 -- 88,803,823(-) GCGTA(C/T)GAAAG intron-variant
rs10489886 -- 88,799,507(-) CAAGT(A/G)AACTT intron-variant
rs10489887 -- 88,781,214(-) GAGAC(A/G)AACCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PKN2 Gene

Variant ID Type Subtype PubMed ID
dgv22n27 CNV gain 19166990
dgv359n54 CNV gain 21841781
dgv360n54 CNV gain 21841781
esv2665922 CNV deletion 23128226
esv3306396 CNV mobile element insertion 20981092
esv3307993 CNV mobile element insertion 20981092
esv3308381 CNV mobile element insertion 20981092
esv3340558 CNV insertion 20981092
esv3403767 CNV insertion 20981092
esv3428030 CNV insertion 20981092
esv3450284 CNV insertion 20981092
esv3586738 CNV loss 21293372
esv3586743 CNV loss 21293372
esv3586744 CNV loss 21293372
esv3586745 CNV gain 21293372
esv3586746 CNV loss 21293372
nsv1113147 CNV deletion 24896259
nsv1122376 CNV deletion 24896259
nsv462450 CNV gain 19166990
nsv546773 CNV loss 21841781
nsv546781 CNV gain 21841781
nsv830514 CNV loss 17160897
nsv830525 CNV loss 17160897
nsv830537 CNV gain 17160897
nsv946053 CNV duplication 23825009

Variation tolerance for PKN2 Gene

Residual Variation Intolerance Score: 30.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.64; 45.52% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PKN2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PKN2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PKN2 Gene

Disorders for PKN2 Gene

Relevant External Links for PKN2

Genetic Association Database (GAD)
PKN2
Human Genome Epidemiology (HuGE) Navigator
PKN2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PKN2

No disorders were found for PKN2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PKN2 Gene

Publications for PKN2 Gene

  1. Cloning and expression patterns of two members of a novel protein- kinase-C-related kinase family. (PMID: 7851406) Palmer R.H. … Parker P.J. (Eur. J. Biochem. 1995) 2 3 4 22 64
  2. Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases. (PMID: 20188095) Harrison B.C. … McKinsey T.A. (FEBS Lett. 2010) 3 4 22 64
  3. The C-terminus of PRK2/PKNgamma is required for optimal activation by RhoA in a GTP-dependent manner. (PMID: 18835241) Lim W.G. … Duan W. (Arch. Biochem. Biophys. 2008) 3 4 22 64
  4. Identification of Grb4/Nckbeta, a src homology 2 and 3 domain- containing adapter protein having similar binding and biological properties to Nck. (PMID: 10026169) Braverman L.E. … Quilliam L.A. (J. Biol. Chem. 1999) 3 4 22 64
  5. Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy. (PMID: 9368003) Cryns V.L. … Yuan J. (J. Biol. Chem. 1997) 3 4 22 64

Products for PKN2 Gene

Sources for PKN2 Gene

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