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Aliases for PKD1P6 Gene

Aliases for PKD1P6 Gene

  • Polycystin 1, Transient Receptor Potential Channel Interacting Pseudogene 6 2 3 5
  • Polycystic Kidney Disease 1 (Autosomal Dominant) Pseudogene 6 2 3
  • GPS, PLAT And Transmembrane Domain-Containing Protein 3
  • HG6 3

External Ids for PKD1P6 Gene

Previous GeneCards Identifiers for PKD1P6 Gene

  • GC16U900294
  • GC16M015185
  • GC16M015106
  • GC16M015126
  • GC16M015199
  • GC16M015219
  • GC16M015202

Summaries for PKD1P6 Gene

GeneCards Summary for PKD1P6 Gene

PKD1P6 (Polycystin 1, Transient Receptor Potential Channel Interacting Pseudogene 6) is a Pseudogene. Diseases associated with PKD1P6 include Polycystic Kidney Disease 1, Autosomal Dominant.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PKD1P6 Gene

Genomics for PKD1P6 Gene

Regulatory Elements for PKD1P6 Gene

Enhancers for PKD1P6 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F015970 1.6 FANTOM5 Ensembl ENCODE 29.4 -819.7 -819736 8.2 ZFP64 ETS1 CBX5 GATA2 ZNF143 FOS ZNF263 ZNF202 NFYC REST LOC100505915 PKD1P1 PKD1P6 ABCC1 RRN3 FOPNL NPIPA5 ENSG00000227827 NDE1 GC16P016010
GH16F015588 1.9 FANTOM5 Ensembl ENCODE 18.5 -436.8 -436759 5.4 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF548 ZNF263 SP3 TBX21 MEF2D BFAR ENSG00000263335 LOC100505915 RRN3 PKD1P6 RPL17P40 ENSG00000270734 LOC105371095 ENSG00000263029 NDE1
GH16F015517 1.7 FANTOM5 Ensembl ENCODE 10.6 -366.4 -366388 6.5 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 ZNF2 SLC30A9 SP5 MXD4 C16orf45 KIAA0430 RPL17P40 ENSG00000270734 LOC105371095 ENSG00000263029 BFAR LOC100505915 PKD1P6 RRN3
GH16F015487 1.7 FANTOM5 Ensembl ENCODE 10.2 -336.6 -336610 7.6 ATF1 PKNOX1 ZNF133 ARID4B YBX1 BRCA1 YY1 ZNF121 FOS SP5 C16orf45 ENSG00000183889 ENSG00000183458 PKD1P1 NPIPA3 ENSG00000261819 LOC100505915 NPIPA5 ENSG00000227827 NPIPA2
GH16F015992 1.7 FANTOM5 Ensembl ENCODE 10.2 -842.4 -842350 8.6 MLX SIN3A ARID4B DMAP1 SLC30A9 FOS SP5 MXD4 KAT8 MEF2D ABCC1 ENSG00000183889 PKD1P1 RNU6-213P FOPNL LOC100505915 ENSG00000227827 NPIPA5 PKD1P6 NDE1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PKD1P6 on UCSC Golden Path with GeneCards custom track

Promoters for PKD1P6 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000504310 64 2201 HDGF ELF3 TBP ARID4B DMAP1 EGR1 ZNF366 EGR2 THAP11 GMEB2
ENSR00001799889 1664 201

Genomic Location for PKD1P6 Gene

Chromosome:
16
Start:
15,104,723 bp from pter
End:
15,154,564 bp from pter
Size:
49,842 bases
Orientation:
Minus strand

Genomic View for PKD1P6 Gene

Genes around PKD1P6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PKD1P6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PKD1P6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PKD1P6 Gene

Proteins for PKD1P6 Gene

Post-translational modifications for PKD1P6 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PKD1P6 Gene

Domains & Families for PKD1P6 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PKD1P6 Gene

Function for PKD1P6 Gene

Phenotypes for PKD1P6 Gene

GenomeRNAi human phenotypes for PKD1P6:
genes like me logo Genes that share phenotypes with PKD1P6: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PKD1P6 Gene

Localization for PKD1P6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PKD1P6 Gene

Pathways & Interactions for PKD1P6 Gene

SuperPathways for PKD1P6 Gene

No Data Available

Interacting Proteins for PKD1P6 Gene

Gene Ontology (GO) - Biological Process for PKD1P6 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PKD1P6 Gene

Transcripts for PKD1P6 Gene

mRNA/cDNA for PKD1P6 Gene

(1) Selected AceView cDNA sequences:
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PKD1P6 Gene

No ASD Table

Relevant External Links for PKD1P6 Gene

GeneLoc Exon Structure for
PKD1P6
ECgene alternative splicing isoforms for
PKD1P6

Expression for PKD1P6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PKD1P6 Gene

Protein differential expression in normal tissues from HIPED for PKD1P6 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for PKD1P6 Gene



Protein tissue co-expression partners for PKD1P6 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PKD1P6 Gene:

PKD1P6
genes like me logo Genes that share expression patterns with PKD1P6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PKD1P6 Gene

Orthologs for PKD1P6 Gene

Evolution for PKD1P6 Gene

ENSEMBL:
Gene Tree for PKD1P6 (if available)
TreeFam:
Gene Tree for PKD1P6 (if available)

No data available for Orthologs for PKD1P6 Gene

Paralogs for PKD1P6 Gene

No data available for Paralogs for PKD1P6 Gene

Variants for PKD1P6 Gene

Structural Variations from Database of Genomic Variants (DGV) for PKD1P6 Gene

Variant ID Type Subtype PubMed ID
esv3638024 CNV loss 21293372
esv3638025 CNV gain 21293372
nsv1036298 CNV gain 25217958
nsv1038955 CNV loss 25217958
nsv1050325 CNV loss 25217958
nsv1053467 CNV loss 25217958
nsv1115491 CNV duplication 24896259
nsv1144758 CNV deletion 24896259
nsv511045 OTHER complex 20534489
nsv7277 OTHER inversion 18451855
nsv9359 CNV gain+loss 18304495
nsv952934 CNV deletion 24416366
nsv974860 CNV duplication 23825009
nsv977910 CNV duplication 23825009
nsv977911 CNV duplication 23825009
nsv978191 CNV duplication 23825009
nsv984375 CNV duplication 23825009
esv3570354 CNV gain 25503493
esv2762254 CNV gain+loss 21179565
esv2758632 CNV gain+loss 17122850
esv26385 CNV loss 19812545
esv2602193 CNV loss 19546169
dgv2765n100 CNV gain 25217958
dgv2755n100 CNV gain 25217958

Relevant External Links for PKD1P6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PKD1P6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for PKD1P6 Gene

Disorders for PKD1P6 Gene

MalaCards: The human disease database

(1) MalaCards diseases for PKD1P6 Gene - From: GeneCards

Disorder Aliases PubMed IDs
polycystic kidney disease 1, autosomal dominant
  • pkd 1
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for PKD1P6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PKD1P6
genes like me logo Genes that share disorders with PKD1P6: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PKD1P6 Gene

Publications for PKD1P6 Gene

  1. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 2 3 64
  2. The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. (PMID: 8004675) Ward C.J. … Halley D.J.J. (Cell 1994) 2 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for PKD1P6 Gene

Sources for PKD1P6 Gene

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