Aliases for PKD1L3 Gene
External Ids for PKD1L3 Gene
Previous GeneCards Identifiers for PKD1L3 Gene
This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores.[provided by RefSeq, Apr 2009]
GeneCards Summary for PKD1L3 Gene
PKD1L3 (Polycystin 1 Like 3, Transient Receptor Potential Channel Interacting) is a Protein Coding gene. Diseases associated with PKD1L3 include Polycystic Kidney Disease and Polycystic Kidney Disease 1. Among its related pathways are Taste transduction. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and calcium channel activity. An important paralog of this gene is PKDREJ.
UniProtKB/Swiss-Prot for PKD1L3 Gene
Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.