PKD1L2 Gene
protein-coding GIFtS: 51
GCID: GC16M081135
|
|
polycystic kidney disease 1-like 2
| |
Aliases
for PKD1L2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Polycystic Kidney Disease 1-Like 21 2 | | Polycystic Kidney Disease Protein 1-Like 22 | | KIAA18791 3 | | Polycystin-1L23 | | PC1L22 3 | | Polycystin-1L23 | | PC1-Like 2 Protein2 3 | | |
Export aliases for PKD1L2 gene to outside databasesPrevious GC identifers: GC16M080885 GC16M080914 GC16M079691 GC16M066891 |
Summaries
for PKD1L2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PKD1L2:
This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, alatrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain.This protein may function as a component of cation channel pores. Two transcript variants encoding different isoformshave been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: PK1L2_HUMAN, Q7Z442Function: May function as an ion-channel regulator. May function as a G-protein-coupled receptor
|
Genomic Views
for PKD1L2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PKD1L2 gene promoter:
Max1 LHX3b/Lhx3b HTF MyoD LCR-F1 S8 GATA-6 LHX3a/Lhx3a Sox9 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for PKD1L2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PKD1L2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q23.2 Ensembl cytogenetic band: 16q23.2 HGNC cytogenetic band: 16q23.2PKD1L2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M081135: view genomic region
(about GC identifiers)
Start:
|
81,134,480 bp from pter |
End:
|
81,253,975 bp from pter |
Size:
|
119,496 bases |
Orientation:
|
minus strand |
|
Proteins
for PKD1L2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PK1L2_HUMAN, Q7Z442 (See
protein sequence)Recommended Name: Polycystic kidney disease protein 1-like 2 precursor Size: 2459 amino acids; 272575 Da
Subunit: May interact via its C-terminus with GNAS and GNAI1
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Developmental stage: Expressed in fetal heart
Sequence caution: Sequence=AAQ73173.1; Type=Frameshift; Positions=2113, 2117; Sequence=AAQ73173.1; Type=Frameshift;Positions=2114, 2218; Sequence=BAB67772.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=BAC05222.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q6UEE1 Q6ZN46 Q6ZSP2 Q8N1H9 Q96CL2 Q96Q08Alternative splicing: 7 isoforms: Q7Z442-1 Q7Z442-2 Q7Z442-3 Q7Z442-4 Q7Z442-5 Q7Z442-6 Q7Z442-7 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for PKD1L2: NX_Q7Z442
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z442
PKD1L2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001070248.1 NP_443124.3
ENSEMBL proteins: ENSP00000434644 ENSP00000434417 ENSP00000436309 ENSP00000436389 ENSP00000432818 ENSP00000337397
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
PKD1L2 for ontologies About GeneDecksing
PKD1L2 Antibody Products:
Assay Products for PKD1L2: |
Protein
Domains /
Families
for PKD1L2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PKD1L2 for domains About GeneDecksing
5/11 InterPro domains/families (see all 11):Graphical View of Domain Structure for InterPro Entry Q7Z442ProtoNet protein and cluster: Q7Z442 1 Blocks protein family: IPB000922 D-galactoside/L-rhamnose binding SUEL lectin domain
UniProtKB/Swiss-Prot: PK1L2_HUMAN, Q7Z442Similarity: Belongs to the polycystin familySimilarity: Contains 1 C-type lectin domainSimilarity: Contains 1 GPS domainSimilarity: Contains 1 PLAT domainSimilarity: Contains 1 REJ domainSimilarity: Contains 1 SUEL-type lectin domain |
Function
for PKD1L2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PK1L2_HUMAN, Q7Z442Function: May function as an ion-channel regulator. May function as a G-protein-coupled receptor
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PKD1L2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PKD1L2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for PKD1L2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PKD1L2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKD1L2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
PKD1L2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for PKD1L2:
|
Pathways & Interactions
for PKD1L2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q | | | 2 | Adenylate cyclase-activating neuropeptides | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for PKD1L2
PKD1L2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PKD1L2
1 Interacting protein for PKD1L2 (Q7Z4423) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006811 | ion transport |
IEA | -- | | GO:0007218 | neuropeptide signaling pathway |
IEA | -- |
PKD1L2 for ontologies About GeneDecksing
|
Drugs & Compounds
for PKD1L2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PKD1L2
Search CenterWatch for drugs/clinical trials and news about PKD1L2 / PK1L2
|
Transcripts
for PKD1L2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PKD1L2 gene (3 alternative transcripts): NM_001076780.1 NM_052892.3 NM_182740.1 Unigene Cluster for PKD1L2: Polycystic kidney disease 1-like 2 Hs.413525 [show with all ESTs]Unigene Representative Sequence: NM_05289212 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000534447 ENST00000534142(uc002fgf.1) ENST00000533478(uc002fgg.1)
ENST00000525539(uc002fgh.1) ENST00000530363 ENST00000299598 ENST00000529079
ENST00000531391(uc002fgi.3) ENST00000526632 ENST00000527937(uc002fgk.1 uc002fgl.1)
ENST00000529791 ENST00000337114(uc002fgj.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PKD1L2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PKD1L2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): PKD1L2 (NM_052892) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PKD1L2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PKD1L2 |
Additional cDNA sequence: AK098052.1 AK127266.1 AK131378.1 AL832135.1 AY164483.1 AY371495.1 BC004562.2 BC014157.2 CR627341.1 8 DOTS entries: DT.100649542 DT.92028011 DT.100740302 DT.102822899 DT.99930336 DT.97836505 DT.100001488 DT.95291811 24/37 AceView cDNA sequences (see all 37): BE503919 AA669315 BX115637 BM840998 BC014157 BC004562 BM841886 AA157971 BG104257 AB067466 CA397713 BM761480 CR627341 BX481943 CB266350 AI825072 BI861303 AK098052 NM_052892 AY164483 BM841509 BG718223 NM_182740 CA438401
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for PKD1L2 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 23 | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30a | · | 30b | ^ | 31a | · | 31b | ^ | 32 | ^ | 33a | · | 33b | ^ | 34a | · | 34b | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41a | · | 41b |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | - | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | - | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PKD1L2
|
Expression
for PKD1L2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PKD1L2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCCAAATAAA
About this image
See PKD1L2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PKD1L2
SOURCE GeneReport for Unigene cluster: Hs.413525
UniProtKB/Swiss-Prot: PK1L2_HUMAN, Q7Z442Tissue specificity: Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver.Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney
SABiosciences Custom PCR Arrays for PKD1L2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PKD1L2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PKD1L2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PKD1L2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PKD1L2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKD1L2 |
Orthologs
for PKD1L2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for PKD1L2 gene from 3/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Pkd1l21 , 5 |
polycystic kidney disease 1 like 21, 5 |
79.98(n)1
74.3(a)1 |
|
8 (63.45 cM)5
766451 NM_029686.41 NP_083962.41
1169956795 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.326802 |
Xenopus laevis transcribed sequence with weak similarity more |
77.66(n) |
|
BJ068659.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
im:71384751 |
im:7138475 |
58.32(n)
53.2(a) |
|
497373 XM_002662913.1 XP_002662959.1 |
ENSEMBL Gene Tree for PKD1L2 (if available)
TreeFam Gene Tree for PKD1L2 (if available) |
Paralogs
for PKD1L2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PKD1L2 gene
3 SIMAP similar genes for PKD1L2 using alignment to 5 protein entries: PK1L2_HUMAN (see all proteins):DKFZp686J19100 PKD2L2 PKD1L3
PKD1L2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for PKD1L2
PGOHUM00000258025
|
Genomic Variants
for PKD1L2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PKD1L2 (81134480 - 81253975 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for PKD1L2
8 CNVs: 67060 39189 72631 49781 8830 67059 39190 5331
1 Indel: 25689 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PKD1L2 |
|
Disorders
/ Diseases
for PKD1L2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PKD1L2 for disorders About GeneDecksing
OMIM gene information: 607894
OMIM disorders: --
5  diseases for PKD1L2: About MalaCardspolycystic kidney disease kidney disease conduct disorder adhd
cholesterol
1 disease from the University of Copenhagen DISEASES database for PKD1L2:Polycystic kidney disease Human Genome Epidemiology (HuGE) Navigator: PKD1L2 (3 documents)
Export disorders for PKD1L2 gene to outside databases
|
Publications
for PKD1L2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PKD1L2 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with PKD1L2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes. (PubMed id 12782129)1, 2, 3 Li A.... Somlo S. (2003)
- Polycystin-1L2 is a novel G-protein-binding protein. (PubMed id 15203210)1, 2 Yuasa T.... Zhou J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2 Nagase T....Ohara O. (2001)
- Fine mapping and association studies of a high-densit y lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian su bjects. (PubMed id 19844255)1 Dastani Z....Genest J. (2010)
- Upregulation of PKD1L2 provokes a complex neuromuscul ar disease in the mouse. (PubMed id 19578180)1 Mackenzie F.E....Blanco G. (2009)
- Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PubMed id 18951430)1 Anney R.J....Gill M. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for PKD1L2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PKD1L2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PKD1L2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing PKD1L2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PKD1L2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PKD1L2 gene:
Search GeneIP for patents involving PKD1L2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PKD1L2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PKD1L2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PKD1L2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PKD1L2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PKD1L2 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PKD1L2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PKD1L2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PKD1L2 | | OriGene Custom Protein Services for PKD1L2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PKD1L2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PKD1L2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PKD1L2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PKD1L2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PKD1L2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PKD1L2 |
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| | | | Search Tocris compounds for PKD1L2 |
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 | | | PKD1L2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PKD1L2 |
|  |  |  | | | | ThermoFisher Antibodies for PKD1L2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PKD1L2 |
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