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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PITPNM2 Gene

protein-coding   GIFtS: 50
GCID: GC12M123468

Phosphatidylinositol Transfer Protein, Membrane-Associated...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Phosphatidylinositol Transfer Protein, Membrane-Associated 21 2 3     RDGB22
Pyk2 N-Terminal Domain-Interacting Receptor 32 3     RDGBA22
NIR-32 3     Membrane-Associated Phosphatidylinositol Transfer Protein 22
NIR32 3     Retinal Degeneration B Alpha 22
PITPnm 22 3     KIAA14573

External Ids:    HGNC: 210441   Entrez Gene: 576052   Ensembl: ENSG000000909757   OMIM: 6089205   UniProtKB: Q9BZ723   

Export aliases for PITPNM2 gene to outside databases

Previous GC identifers: GC12M123276 GC12M121905 GC12M121907 GC12M121992 GC12M120429


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PITPNM2 Gene:
PITPNM2 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that
share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 (PubMed
15627748)).(supplied by OMIM, Mar 2008)

GeneCards Summary for PITPNM2 Gene: 
PITPNM2 (phosphatidylinositol transfer protein, membrane-associated 2) is a protein-coding gene. Diseases associated with PITPNM2 include retinal degeneration, and retinitis. GO annotations related to this gene include lipid binding and calcium ion binding. An important paralog of this gene is PITPNC1.

UniProtKB/Swiss-Prot: PITM2_HUMAN, Q9BZ72
Function: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro).
Binds calcium ions




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_009755.19  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PITPNM2 gene promoter:
         Max1   USF1   SRY   POU2F1   FOXJ2 (long isoform)   POU2F1a   USF-1   FOXJ2   TGIF   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPITPNM2 promoter sequence
   Search SABiosciences Chromatin IP Primers for PITPNM2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PITPNM2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

PITPNM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PITPNM2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M123468:  view genomic region     (about GC identifiers)

Start:
123,468,027 bp from pter      End:
123,634,562 bp from pter
Size:
166,536 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PITM2_HUMAN, Q9BZ72 (See protein sequence)
Recommended Name: Membrane-associated phosphatidylinositol transfer protein 2  
Size: 1349 amino acids; 148933 Da
Subunit: Interacts with PTK2B via its C-terminus
Subcellular location: Endomembrane system; Peripheral membrane protein
Sequence caution: Sequence=BAA95981.2; Type=Erroneous initiation;
Secondary accessions: Q9P271
Alternative splicing: 3 isoforms:  Q9BZ72-1   Q9BZ72-2   Q9BZ72-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PITPNM2: NX_Q9BZ72

Explore proteomics data for PITPNM2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BZ72

  • PITPNM2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PITPNM2 Protein Expression
    REFSEQ proteins: NP_065896.1  
    ENSEMBL proteins: 
     ENSP00000280562   ENSP00000437611   ENSP00000474962   ENSP00000437869   ENSP00000445399  
     ENSP00000322218   ENSP00000376223  

    Human Recombinant Protein Products for PITPNM2: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PITPNM2 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0012505endomembrane system IEA--
    GO:0016021integral to membrane NAS10022914
    GO:0043231intracellular membrane-bounded organelle IDA--

    PITPNM2 for ontologies           About GeneDecksing



    PITPNM2 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5 InterPro protein domains:
     IPR013209 LNS2
     IPR023214 HAD-like_dom
     IPR004177 DDHD
     IPR023393 START-like_dom
     IPR001666 PI_transfer

    Graphical View of Domain Structure for InterPro Entry Q9BZ72

    ProtoNet protein and cluster: Q9BZ72

    1 Blocks protein domain: IPB001666 Phosphatidylinositol transfer protein signature

    UniProtKB/Swiss-Prot: PITM2_HUMAN, Q9BZ72
    Similarity: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily
    Similarity: Contains 1 DDHD domain


    PITPNM2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PITM2_HUMAN, Q9BZ72
    Function: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro).
    Binds calcium ions

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding NAS10022914
    GO:0008289lipid binding IEA--
    GO:0046872metal ion binding ----
         
    PITPNM2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Pitpnm2):
     normal 

    PITPNM2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Pitpnm2tm1Tili for PITPNM2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for PITPNM2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PITPNM2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PITPNM2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PITPNM2 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PITPNM2
    8/84 QIAGEN miScript miRNA Assays for microRNAs that regulate PITPNM2 (see all 84):
    hsa-miR-376b hsa-miR-128 hsa-miR-30d hsa-miR-219-5p hsa-miR-3653 hsa-miR-342-3p hsa-miR-30a hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidPITPNM2 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PITPNM2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PITPNM2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/14 Interacting proteins for PITPNM2 (Q9BZ723 ENSP000003222184) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTK2BQ142893, ENSP000003328164I2D: score=2 STRING: ENSP00000332816
    CPNE1Q998293, ENSP000003172574I2D: score=1 STRING: ENSP00000317257
    ARRB1P494073I2D: score=1 
    CPNE4Q96A233I2D: score=1 
    FGFR3P226073I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0008152metabolic process NAS10022914

    PITPNM2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PITPNM2 (PITM2)

    10/1455 HMDB Compounds for PITPNM2 (see all 1455)    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    PC(14:0/14:0)Phosphatidylcholine(14:0/14:0) (see all 8)----
    PC(14:0/14:1(9Z))Phosphatidylcholine(14:0/14:1) (see all 14)----
    PC(14:0/15:0)GPCho(14:0/15:0) (see all 8)----
    PC(14:0/16:0)GPCho(30:0) (see all 8)----
    PC(14:0/16:1(9Z))1-myristoyl-2-palmitoleoyl-sn-glycero-3-phosphocholine (see all 14)----
    PC(14:0/18:0)1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine (see all 8)----
    PC(14:0/18:1(11Z))Phosphatidylcholine(14:0/18:1w7) (see all 14)----
    PC(14:0/18:1(9Z))1-myristoyl-2-oleoyl-sn-glycero-3-phosphocholine (see all 14)----
    PC(14:0/18:2(9Z,12Z))Phosphatidylcholine(32:2) (see all 14)----

    Search CenterWatch for drugs/clinical trials and news about PITPNM2 / PITM2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PITPNM2 gene: 
    NM_020845.2  

    Unigene Cluster for PITPNM2:

    Phosphatidylinositol transfer protein, membrane-associated 2
    Hs.272759  [show with all ESTs]
    Unigene Representative Sequence: AB040890
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000280562(uc001uek.1) ENST00000542749 ENST00000436074 ENST00000546049
    ENST00000451868(uc009zxu.1) ENST00000542210 ENST00000535289 ENST00000541244
    ENST00000320201(uc001uej.1) ENST00000392428
    miRNA
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    8/84 QIAGEN miScript miRNA Assays for microRNAs that regulate PITPNM2 (see all 84):
    hsa-miR-376b hsa-miR-128 hsa-miR-30d hsa-miR-219-5p hsa-miR-3653 hsa-miR-342-3p hsa-miR-30a hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidPITPNM2 3' UTR sequence
    Inhib. RNA
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PITPNM2
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PITPNM2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PITPNM2

    Additional mRNA sequence: 

    AB040890.2 AF334585.1 AK026156.1 AL133612.1 BC025360.1 BC040063.1 BC050567.1 BC141813.1 

    6 DOTS entries:

    DT.100742290  DT.439502  DT.121149386  DT.121149342  DT.121149363  DT.121149375 

    24/80 AceView cDNA sequences (see all 80):

    AI650815 AW590553 AL549956 AB040890 AI673017 BM717063 BM703287 AI652082 
    R19190 BU732093 BM757394 BC025360 AI611064 BM792645 AL133612 AI207141 
    BC040063 AI989918 BU731117 BC050567 BI766127 NM_020845 BF353740 BU541008 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PITPNM2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGTTACAC
    PITPNM2 Expression
    About this image


    See PITPNM2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PITPNM2

    SOURCE GeneReport for Unigene cluster: Hs.272759

    UniProtKB/Swiss-Prot: PITM2_HUMAN, Q9BZ72
    Tissue specificity: Highly expressed in brain, heart, ovary, testis and thymus. Detected in small intestine,
    prostate, pancreas, skeletal muscle, liver, colon and placenta

        SABiosciences Custom PCR Arrays for PITPNM2
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PITPNM2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PITPNM2 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pitpnm21 , 5 phosphatidylinositol transfer protein, membrane-associated 2 less1, 5 86.73(n)1
    90.79(a)1
      5 (63.39 cM)5
    196791  NM_011256.21  NP_035386.11 
     1241186905 
    chicken
    (Gallus gallus)
    Aves PITPNM21 phosphatidylinositol transfer protein, membrane-associated 2 less 74.22(n)
    81.28(a)
      416830  XM_415122.3  XP_415122.3 
    lizard
    (Anolis carolinensis)
    Reptilia PITPNM26
    phosphatidylinositol transfer protein, membrane-as...
    70(a)
    1 ↔ 1
    LGb(1909930-2010003)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003339011 membrane-associated phosphatidylinositol transfer protein 2-like less 67.56(n)
    65.86(a)
      100333901  XM_002663669.2  XP_002663715.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta rdgB1 retinal degeneration B 57.34(n)
    51.73(a)
      32340  NM_001014740.1  NP_001014740.1 
    worm
    (Caenorhabditis elegans)
    Secernentea pitp-11 Protein PITP-1 49.71(n)
    45.14(a)
      175459  NM_065325.2  NP_497726.2 


    ENSEMBL Gene Tree for PITPNM2 (if available)
    TreeFam Gene Tree for PITPNM2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PITPNM2 gene
    PITPNC12  PITPNB2  PITPNM32  PITPNM12  PITPNA2  
    6 SIMAP similar genes for PITPNM2 using alignment to 6 protein entries:     PITM2_HUMAN (see all proteins):
    DKFZp434P0917    PITPNM1    PITPNM3    PITPNA    PITPNC1    PITPNB

    PITPNM2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1915 SNPs in PITPNM2 are shown (see all 1915)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1854938561,2
    --123467988(+) CCACCA/GTGCCC 1 -- int10--------
    rs1498506391,2
    C--123468546(+) GGAGGC/TGGAAA 1 -- ut310--------
    rs1157436901,2
    --123468557(+) GCAGAC/TCTGGA 1 -- ut310--------
    rs1458868451,2
    --123468572(+) GAAGAA/GACTTC 1 -- ut310--------
    rs1490222841,2
    --123468657(+) GTTGTC/TCTTGG 1 -- ut310--------
    rs673060851,2
    C--123468733(+) GAGGCT/CGAGCC 1 -- ut312Minor allele frequency- C:0.03NA 122
    rs1907942741,2
    --123469081(+) TTTTTC/TCTCTG 1 -- ut310--------
    rs15689181,2
    C--123469141(+) TTACAC/G/TGACCC 2 -- ut31 ese35MN NA CSA WA EA 425
    rs1466853651,2
    C--123469170(+) CACACA/GGGAAA 1 -- ut310--------
    rs1402804771,2
    --123469240(+) AGGTCA/GGCCGT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for PITPNM2 (123468027 - 123634562 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for PITPNM2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2646329CNV Deletion19546169
    nsv914CNV Insertion18451855
    dgv1497n71CNV Loss21882294
    nsv455732CNV Loss19166990
    dgv22n68CNV Loss17160897
    nsv899577CNV Loss21882294
    nsv517200CNV Loss19592680
    nsv899578CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608920    OMIM disorders: --

    3 diseases for PITPNM2:    About MalaCards
    retinal degeneration    retinitis    prostatitis

    1 disease from the University of Copenhagen DISEASES database for PITPNM2:
    Retinal degeneration

    PITPNM2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): PITPNM2

    Export disorders for PITPNM2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PITPNM2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with PITPNM2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein. (PubMed id 10022914)1, 2, 3, 9 Lev S....Schlessinger J. (1999)
    2. Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. (PubMed id 21507922)1, 4 Ramsuran V....Ndung'u T. (2011)
    3. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2 Nagase T.... Ohara O. (2000)
    4. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. (PubMed id 22361696)2 Stadler C.... Lundberg E. (2012)
    5. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    6. Chromosomal localization, genomic organization and evolution of the genes encoding human phosphatidylinositol transfer protein membrane- associated (PITPNM) 1, 2 and 3. (PubMed id 15627748)1 Ocaka L.... Halford S. (2005)
    7. Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif. (PubMed id 12522145)1 Tomsig J.L....Creutz C.E. (2003)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57605 HGNC: 21044 AceView: PITPNM2 Ensembl:ENSG00000090975 euGenes: HUgn57605
    ECgene: PITPNM2 H-InvDB: PITPNM2

    (According to HUGE)
    About This Section
    HUGE: KIAA1457

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PITPNM2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PITPNM2 gene:
    Search GeneIP for patents involving PITPNM2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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