Aliases for PITPNA Gene
External Ids for PITPNA Gene
Previous HGNC Symbols for PITPNA Gene
Previous GeneCards Identifiers for PITPNA Gene
This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.[provided by RefSeq, Sep 2009]
GeneCards Summary for PITPNA Gene
PITPNA (Phosphatidylinositol Transfer Protein Alpha) is a Protein Coding gene. Diseases associated with PITPNA include hereditary choroidal atrophy and partial central choroid dystrophy. Among its related pathways are EGFR1 Signaling Pathway and Developmental Biology. GO annotations related to this gene include lipid binding and phosphatidylcholine transporter activity. An important paralog of this gene is PITPNM2.
UniProtKB/Swiss-Prot for PITPNA Gene
Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.