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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PIP4K2C Gene

protein-coding   GIFtS: 54
GCID: GC12P057985

phosphatidylinositol-5-phosphate 4-kinase, type II, gamma

(Previous names: phosphatidylinositol-4-phosphate 5-kinase, type II, gamma...)
(Previous symbol: PIP5K2C)
 Explore 2 diseases affiliated with
PIP4K2C via our new
 Human Malady Compendium 
Biological research products
for PIP4K2C
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, Gamma1 2     EC 2.7.1.1493 8
PIP5K2C1 2 3     FLJ220551
Phosphatidylinositol-4-Phosphate 5-Kinase, Type II, Gamma1 2     Phosphatidylinositol 4-Phosphate 5-Kinase2
Phosphatidylinositol 5-Phosphate 4-Kinase Type II Gamma2 3     Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 Gamma2
PIP4KII-Gamma1     Phosphatidylinositol-5-Phosphate 4-Kinase Type-2 Gamma2
PI(5)P 4-Kinase Type II Gamma2 3     EC 2.7.18

External Ids:    HGNC: 237861   Entrez Gene: 798372   Ensembl: ENSG000001669087   UniProtKB: Q8TBX83   

Export aliases for PIP4K2C gene to outside databases

Previous GC identifers: GC12P056272 GC12P055022


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PI42C_HUMAN, Q8TBX8
Function: May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic
reticulum (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PIP4K2C gene promoter:
         Egr-3   Sox5   Spz1   AML1a   MyoD   IRF-1   RORalpha1   ARP-1   ZID   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPIP4K2C promoter sequence
   Search SABiosciences Chromatin IP Primers for PIP4K2C

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PIP4K2C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.3   HGNC cytogenetic band: 12q13.2

PIP4K2C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PIP4K2C gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P057985:  view genomic region     (about GC identifiers)

Start:
57,984,942 bp from pter      End:
57,997,211 bp from pter
Size:
12,270 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PI42C_HUMAN, Q8TBX8 (See protein sequence)
Recommended Name: Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma  
Size: 421 amino acids; 47300 Da
Subcellular location: Cytoplasm. Membrane. Note=Mostly found in the cytosol and surrounding plasma membrane. However,
its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis (By similarity)
Sequence caution: Sequence=BAB15223.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for PIP4K2C:
2GK9 (3D)    
Secondary accessions: B2RDL3 B4DM11 B4DY44 Q9H6N2
Alternative splicing: 3 isoforms:  Q8TBX8-1   Q8TBX8-2   Q8TBX8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PIP4K2C: NX_Q8TBX8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TBX8

  • 4/21 DME Specific Peptides for PIP4K2C (Q8TBX8) (see all 21)
     PLGPGEF  DYSLLLG  IMDYSLL  KRFLDFI 

    PIP4K2C Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001139730.1  NP_001139731.1  NP_001139732.1  NP_079055.3  

    ENSEMBL proteins: 
     ENSP00000412035   ENSP00000439878   ENSP00000450197   ENSP00000447390   ENSP00000449335  
     ENSP00000448042   ENSP00000347032   ENSP00000449538  

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    Novus Biologicals PIP4K2C Proteins
    Novus Biologicals PIP4K2C Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PIP4K2C

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0016020membrane IEA--


    PIP4K2C for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PIP4K2C for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR002498 PInositol-4-P-5-kinase_core
     IPR016034 PInositol-4P-5-kinase_core_sub
     IPR023610 PInositol-4-P-5-kinase

    Graphical View of Domain Structure for InterPro Entry Q8TBX8

    ProtoNet protein and cluster: Q8TBX8

    1 Blocks protein family: IPB002498 Phosphatidylinositol-4-phosphate 5-kinase

    UniProtKB/Swiss-Prot: PI42C_HUMAN, Q8TBX8
    Similarity: Contains 1 PIPK domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: PI42C_HUMAN, Q8TBX8
    Function: May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic
    reticulum (By similarity)
    Catalytic activity: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol
    4,5-bisphosphate

    Enzyme Numbers (IUBMB): EC 2.7.1.1491 2 EC 2.7.12

    miRNA
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    hsa-miR-15a hsa-miR-1224-3p hsa-miR-106a hsa-miR-519a hsa-miR-1273d hsa-miR-1244 hsa-miR-637 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidPIP4K2C 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005524ATP binding IEA--
    GO:0016307phosphatidylinositol phosphate kinase activity ----
    GO:00163091-phosphatidylinositol-5-phosphate 4-kinase activity IEA--
    GO:0042802identical protein binding IPI18255255


    PIP4K2C for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for PIP4K2C:
     Increased G2M DNA content  Increased cell size 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Inositol phosphate metabolism
    Inositol phosphate metabolism1.00
    Phosphatidylinositol signaling system0.59
    superpathway of inositol phosphate compounds0.59
    2D-myo-inositol-5-phosphate metabolism
    D-myo-inositol-5-phosphate metabolism1.00
    D-myo-inositol (1,4,5)-trisphosphate biosynthesis0.50
    3Regulation of Actin Cytoskeleton
    Regulation of Actin Cytoskeleton1.00
    Regulation of actin cytoskeleton0.58
    4B Cell Receptor Signaling Pathway
    B Cell Receptor Signaling Pathway1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5 BioSystems Pathways for PIP4K2C 
        D-myo-inositol-5-phosphate metabolism
    Regulation of Actin Cytoskeleton
    B Cell Receptor Signaling Pathway
    D-myo-inositol (1,4,5)-trisphosphate biosynthesis
    superpathway of inositol phosphate compounds


    3         Kegg Pathways  (Kegg details for PIP4K2C):
        Inositol phosphate metabolism
    Phosphatidylinositol signaling system
    Regulation of actin cytoskeleton


    PIP4K2C for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PIP4K2C

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/47 Interacting proteins for PIP4K2C (Q8TBX81, 3 ENSP000003470324) via UniProtKB, MINT, STRING, and/or I2D (see all 47)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BTKQ061873, ENSP000003081764I2D: score=1 STRING: ENSP00000308176
    STK11Q158313I2D: score=1 
    PIP4K2CQ8TBX81EBI-1383637,EBI-1383637
    PIK3CGENSP000003521214STRING: ENSP00000352121
    PIK3R3ENSP000002627414STRING: ENSP00000262741
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PIP4K2C

    3 HMDB Compounds for PIP4K2C    About this table
    CompoundSynonyms CAS #PubMed Ids
    1-Phosphatidyl-D-myo-inositol1-Phosphatidyl-1D-myo-inositol (see all 6)----
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Search CenterWatch for drugs/clinical trials and news about PIP4K2C / PI42C 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PIP4K2C gene (4 alternative transcripts): 
    NM_001146258.1  NM_001146259.1  NM_001146260.1  NM_024779.4  

    Unigene Cluster for PIP4K2C:

    Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
    Hs.144502  [show with all ESTs]
    Unigene Representative Sequence: NM_024779
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000422156 ENST00000540759(uc001sou.3) ENST00000551772 ENST00000550465
    ENST00000550360 ENST00000550095 ENST00000354947(uc001sot.3 uc010srs.2 uc010srt.2)
    ENST00000548264

    miRNA
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    8/71 QIAGEN miScript miRNA Assays for microRNAs that regulate PIP4K2C (see all 71):
    hsa-miR-15a hsa-miR-1224-3p hsa-miR-106a hsa-miR-519a hsa-miR-1273d hsa-miR-1244 hsa-miR-637 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidPIP4K2C 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AK025708.1 AK075553.1 AK125526.1 AK225343.1 AK225685.1 AK297243.1 AK302254.1 AK315588.1 
    BC028596.2 

    4 DOTS entries:

    DT.100023427  DT.423411  DT.95269954  DT.100023424 

    24/94 AceView cDNA sequences (see all 94):

    AW613378 CA416301 AW006936 AK125526 BG259815 AX754970 AI872266 AL561242 
    BQ720571 BX098965 CR617906 AL119465 AI701315 AA897785 AW629819 CA415852 
    AK075553 CD557503 BG403155 BX376422 NM_024779 BQ954092 BG119701 BP375862 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for PIP4K2C (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                -                       -                                                   
    SP2:                                                        -                                                   
    SP3:                                                                                                            
    SP4:                                                                                -                           
    SP5:                                                  -     -                                                   


    ECgene alternative splicing isoforms for PIP4K2C

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PIP4K2C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGCCATAGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See PIP4K2C Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PIP4K2C

    SOURCE GeneReport for Unigene cluster: Hs.144502
        SABiosciences Custom PCR Arrays for PIP4K2C
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIP4K2C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PIP4K2C gene from 5/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia PIP4K2C6
    --
    76(a)
    1 ↔ 1
    GL343212.1(296895-340327)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.34452 Transcribed sequence with weak similarity to protein more 75.92(n)    142026509 
    zebrafish
    (Danio rerio)
    Actinopterygii pip5k22 phosphatidylinositol-4-phosphate 5-kinase, type II 77.53(n)   373124  BC045883.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG174716
    --
    49(a)
    1 → many
    4(1213042-1217466)
    worm
    (Caenorhabditis elegans)
    Secernentea ppk-26
    PIP Kinase family member (ppk-2)
    46(a)
    1 → many
    III(2102285-2107460)


    ENSEMBL Gene Tree for PIP4K2C (if available)
    TreeFam Gene Tree for PIP4K2C (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PIP4K2C gene
    PIP4K2A2  PIP5K1B2  PIP5K1C2  PIP4K2B2  PIP5KL12  PIP5K1A2  
    7 SIMAP similar genes for PIP4K2C using alignment to 5 protein entries:     PI42C_HUMAN (see all proteins):
    PIP4K2B    PIP4K2A    PIPSL    STM7    PIP5K1B    PIP5K1A
    PIP5K1C

    PIP4K2C for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/27 NCBI SNPs in PIP4K2C are shown (see all 27    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2003382941,2
    C--55034440(-) TATGTA/CTAAAA 4 -- ut310--------
    rs118380871,2
    C,H--55035179(+) GCTTGC/TTAACA 4 -- int12Minor allele frequency- T:0.00NA 4
    rs710847691,2
    C--57983702(-) GTCTC-/AAAAAAA 4 -- us2k11Minor allele frequency- AA:0.00NA 2
    rs107130901,2
    C,--57987246(+) ACACC-/TTAGAC 1 -- int12Minor allele frequency- T:0.00NA CSA 4
    rs671015431,2
    C--57989486(-) TTTTT-/TGACAA 1 -- int11Minor allele frequency- T:0.00NA 2
    rs579824101,2
    C--57992308(+) AAAAA-/ATCCAA 1 -- int11Minor allele frequency- A:0.00NA 2
    rs616394291,2
    C--57992354(+) CAGAC-/TTTTTT 1 -- int11Minor allele frequency- T:0.00NA 2
    rs562782121,2
    C--57993832(+) ATCTC-/AAAAA 
     AAAAAAA
    AAAAA
    1 -- int11Minor allele frequency- AAAAAAAAAAAA:0.00CSA 2
    rs723422691,2
    C--57993832(+) ATCTC-/AAAAA 
     AAAAAAA
    AAAAA
    1 -- int10--------
    rs1806953841,2
    --57996847(+) CCATGA/GGGCCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PIP4K2C (57984942 - 57997211 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for PIP4K2C
         1 CNV: 3891

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PIP4K2C for disorders           About GeneDecksing

    2 diseases for PIP4K2C:    About MalaCards
    rheumatoid arthritis    arthritis

    Human Genome Epidemiology (HuGE) Navigator: PIP4K2C (4 documents)

    Export disorders for PIP4K2C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PIP4K2C gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with PIP4K2C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A new pathway for synthesis of phosphatidylinositol-4,5- bisphosphate. (PubMed id 9367159)1, 3 Rameh L.E.... Cantley L.C. (1997)
    2. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    3. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    4. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    5. Genetic variants in the prediction of rheumatoid arth ritis. (PubMed id 20439292)1 van der Helm-van Mil A.H....Huizinga T.W. (2010)
    6. Association of a single-nucleotide polymorphism in CD 40 with the rate of joint destruction in rheumatoid arthritis. (PubMed id 19644859)1 van der Linden M.P....van der Helm-Van Mil A.H. (2009)
    7. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    8. Common variants at CD40 and other loci confer risk of rheumatoid arthritis. (PubMed id 18794853)1 Raychaudhuri S....Plenge R.M. (2008)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79837 HGNC: 23786 AceView: PIP5K2C Ensembl:ENSG00000166908 euGenes: HUgn79837
    ECgene: PIP4K2C Kegg: 79837 H-InvDB: PIP4K2C

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PIP4K2C Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PIP4K2C gene:
    Search GeneIP for patents involving PIP4K2C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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