PINX1 Gene
protein-coding GIFtS: 53
GCID: GC08M010659
|
|
PIN2/TERF1 interacting, telomerase inhibitor 1
| |
Aliases
for PINX1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| PIN2/TERF1 Interacting, Telomerase Inhibitor 11 2 | | MGC88501 | | LPTL1 2 3 | | PinX11 | | LPTS1 2 3 | | 67-11-3 Protein2 | | Liver-Related Putative Tumor Suppressor2 3 | | Hepatocellular Carcinoma-Related Putative Tumor Suppressor2 | | Pin2-Interacting Protein X12 3 | | PIN2 Interacting Protein 12 | | Protein 67-11-32 3 | | PIN2-Interacting Protein 12 | | TRF1-Interacting Protein 12 3 | | PIN2/TERF1-Interacting Telomerase Inhibitor 12 | | FLJ205651 | | |
Export aliases for PINX1 gene to outside databasesPrevious GC identifers: GC08M010685 GC08M010493 GC08M009553 |
Summaries
for PINX1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: PINX1_HUMAN, Q96BK5Function: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERTaccumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cellproliferation and act as tumor suppressor
Gene Wiki entry for PINX1
|
Genomic Views
for PINX1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_077531.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PINX1 gene promoter:
NF-1 AML1a SREBP-1c CUTL1 AP-4 Nkx2-5 FOXL1 RORalpha1 FOXO1a FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PINX1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PINX1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p23 Ensembl cytogenetic band: 8p23.1 HGNC cytogenetic band: 8p23PINX1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M010659: view genomic region
(about GC identifiers)
Start:
|
10,622,473 bp from pter |
End:
|
10,697,394 bp from pter |
Size:
|
74,922 bases |
Orientation:
|
minus strand |
|
Proteins
for PINX1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PINX1_HUMAN, Q96BK5 (See
protein sequence)Recommended Name: PIN2/TERF1-interacting telomerase inhibitor 1 Size: 328 amino acids; 37035 Da
Subunit: Interacts with MCRS1, TERT, TERF1, NCL/nucleolin, and the telomerase RNA
Subcellular location: Nucleus. Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore.Note=Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to thekinetochore is mediated by its central region and depends on NDC80 and CENPE
Secondary accessions: B2R9B1 Q548A5 Q6QWG9 Q7Z7J8 Q96QD7 Q9HBU7 Q9NWW2Alternative splicing: 2 isoforms: Q96BK5-1 Q96BK5-2 Explore the universe of human proteins at neXtProt for PINX1: NX_Q96BK5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96BK5
PINX1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060354.4
ENSEMBL proteins: ENSP00000318966 ENSP00000428853 ENSP00000428728 ENSP00000428242 ENSP00000429346 ENSP00000428347 ENSP00000411396
Human Recombinant Protein Products for PINX1:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
PINX1 for ontologies About GeneDecksing
PINX1 Antibody Products:
Assay Products for PINX1: |
Protein
Domains /
Families
for PINX1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PINX1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96BK5ProtoNet protein and cluster: Q96BK5 1 Blocks protein family: IPB000467 D111/G-patch domain
UniProtKB/Swiss-Prot: PINX1_HUMAN, Q96BK5Domain: The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activityDomain: The TBM domain mediates interaction with TERF1Similarity: Belongs to the PINX1 familySimilarity: Contains 1 G-patch domain |
Function
for PINX1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: PINX1_HUMAN, Q96BK5Function: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERTaccumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cellproliferation and act as tumor suppressor Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
PINX1 for ontologies About GeneDecksing
Phenotypes:
8 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Pinx1):
PINX1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Pinx1tm1.1Kplu for PINX1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PINX1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PINX1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PINX1 (NM_017884) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PINX1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PINX1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PINX1 |
|
Pathways & Interactions
for PINX1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Regulation of Telomerase | |
1  BioSystems Pathway for PINX1
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PINX1
5/102 Interacting proteins for PINX1 (Q96BK51, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 102)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
PINX1 for ontologies About GeneDecksing
|
Drugs & Compounds
for PINX1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PINX1 for compounds About GeneDecksing
 Browse Tocris compounds for PINX1
1 Novoseek chemical compound relationship for PINX1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tin(2+) |
89.5 |
2 |
12768206 (1), 15181449 (1) |
Search CenterWatch for drugs/clinical trials and news about PINX1
|
Transcripts
for PINX1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PINX1 gene: NM_017884.4 Unigene Clusters for PINX1: PIN2/TERF1 interacting, telomerase inhibitor 1 Hs.490991 [show with all ESTs], Hs.583894 [show with all ESTs]Unigene Representative Sequences: AK296724, BC0435739 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000314787(uc003wth.2) ENST00000519088(uc003wti.2) ENST00000524114
ENST00000523559 ENST00000524061 ENST00000517607 ENST00000520018 ENST00000524026
ENST00000426190
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PINX1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PINX1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PINX1 (NM_017884) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PINX1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PINX1 |
Additional cDNA sequence: BC043573.1 8 DOTS entries: DT.443936 DT.97821639 DT.100784494 DT.100784497 DT.95246162 DT.121476717 DT.95158300 DT.40111265 24/110 AceView cDNA sequences (see all 110): CB150183 BM810103 AY238941 AW450745 CR591056 AI650759 BM670522 AL525825 BM974599 F33362 BE466920 BX369048 AW664840 Z41493 CR601705 R60308 AL520524 AW081873 CR620063 BM700406 AA937923 AI243133 BG024436 CB305466
GeneLoc Exon Structure
|
Expression
for PINX1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PINX1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCTGCCGAG
About this image
See PINX1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PINX1
SOURCE GeneReport for Unigene clusters: Hs.490991 Hs.583894
UniProtKB/Swiss-Prot: PINX1_HUMAN, Q96BK5Tissue specificity: Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines
SABiosciences Expression via Pathway-Focused PCR Arrays including PINX1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PINX1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PINX1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PINX1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PINX1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PINX1 |
Orthologs
for PINX1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for PINX1 gene from 8/26 species (see all 26) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Pinx11 , 5 |
PIN2/TERF1 interacting, telomerase inhibitor 11, 5 |
77.4(n)1
73.93(a)1 |
|
14 (33.34 cM)5
724001 NM_028228.31 NP_082504.11
638603125 |
chicken
(Gallus gallus) |
Aves |
PINX11 |
PIN2/TERF1 interacting, telomerase inhibitor 1 |
60.62(n)
54.69(a) |
|
422028 XM_420036.3 XP_420036.3 |
lizard
(Anolis carolinensis) |
Reptilia |
PINX16 |
-- |
78(a) |
1 ↔ 1 |
GL343553.1(399201-404589) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.81972 |
Xenopus laevis transcribed sequence with weak similarity more |
74.51(n) |
|
BM191480.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
pinx12 |
Danio rerio cDNA clone IMAGE5410996, partial cds |
75.88(n) |
|
BC054670.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG111801 |
CG11180 |
46.69(n)
36.28(a) |
|
37330 NM_137651.1 NP_611495.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
T23G7.31 |
Protein T23G7.3 |
46.44(n)
37.59(a) |
|
174456 NM_063554.3 NP_495955.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
PXR1(YGR280C)4
PXR11 |
Essential protein involved in rRNA and snoRNA maturation; more4
Pxr1p1 |
42.17(n)1
31.62(a)1 |
|
7(1051725-1050910)4
8531971, 4 NP_011796.11, 4 |
ENSEMBL Gene Tree for PINX1 (if available)
TreeFam Gene Tree for PINX1 (if available) |
Paralogs
for PINX1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PINX1 gene
2 SIMAP similar genes for PINX1 using alignment to 6 protein entries: PINX1_HUMAN (see all proteins):SOX7 GPATCH4
PINX1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for PINX1
PGOHUM00000243328
|
Genomic Variants
for PINX1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PINX1 (10622473 - 10697394 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 20 variations for PINX1
1 CNV: 52330
3 Indels: 34377 47423 13023
15/16 Inversions (see all 16): 37318 37316 37307 37317 37311 37319 37320 37315 37312 37321 37304 37313 37314 37305 37306 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PINX1 |
|
Disorders
/ Diseases
for PINX1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PINX1 for disorders About GeneDecksing
OMIM gene information: 606505
OMIM disorders: --
8  diseases for PINX1: About MalaCardshepatocellular carcinoma carcinoma telangiectasis acute promyelocytic leukemia
lymphedema gastric cancer breast cancer leukemia
1 disease from the University of Copenhagen DISEASES database for PINX1:Telangiectasis 3 Novoseek disease relationships for PINX1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: PINX1 (2 documents)
Export disorders for PINX1 gene to outside databases
|
Publications
for PINX1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PINX1 gene, integrated from 9 sources (see all 48):
(articles sorted by number of sources associating them with PINX1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor. (PubMed id 11701125)1, 2, 3, 9 Zhou X.Z. and Lu K.P. (2001)
- Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma. (PubMed id 11003615)1, 2, 3 Liao C.... Li T.P. (2000)
- Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cells. (PubMed id 19117989)1, 2, 9 Zhang B.... Huang J.J. (2009)
- Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR. (PubMed id 15381700)1, 2, 9 Banik S.S.R. and Counter C.M. (2004)
- Human PinX1 mediates TRF1 accumulation in nucleolus and enhances TRF1 binding to telomeres. (PubMed id 19265708)1, 2, 9 Yoo J.E.... Park Y.N. (2009)
- PinX1 is recruited to the mitotic chromosome periphery by Nucleolin and facilitates chromosome congression. (PubMed id 19393617)1, 2 Li N....Yao X. (2009)
- PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation. (PubMed id 19553660)1, 2 Yuan K.... Yao X. (2009)
- Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length. (PubMed id 15044100)1, 2 Song H....Zhao M. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for PINX1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PINX1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PINX1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PINX1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PINX1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PINX1 gene:
Search GeneIP for patents involving PINX1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PINX1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for PINX1 | | OriGene shRNA RFP for PINX1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PINX1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PINX1 | | | OriGene Protein Over-expression Lysate for PINX1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PINX1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PINX1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PINX1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PINX1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PINX1 | | OriGene Custom Protein Services for PINX1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PINX1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PINX1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PINX1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PINX1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PINX1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PINX1 |
| |
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|
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PINX1 |
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