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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PILRB Gene

protein-coding   GIFtS: 52
GCID: GC07P099945

Paired Immunoglobin-Like Type 2 Receptor Beta

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Paired Immunoglobin-Like Type 2 Receptor Beta1 2     Cell Surface Receptor FDFACT12
Activating Receptor PILR-Beta2 3     Cell Surface Receptor FDFACT22
Cell Surface Receptor FDFACT2 3     Paired Immunoglobin-Like Receptor Beta2
FDFACT12     Paired Immunoglobulin-Like Receptor Beta2
FDFACT22     Paired Immunoglobulin-Like Type 2 Receptor Beta2
Activating Receptor PILRbeta2     FDFACT3

External Ids:    HGNC: 182971   Entrez Gene: 299902   Ensembl: ENSG000001217167   OMIM: 6053425   UniProtKB: Q9UKJ03   
ORGUL members:         
NONCODE14:n410129 n410128      

Export aliases for PILRB gene to outside databases

Previous GC identifers: GC07P099546 GC07P099545 GC07P099578 GC07P099771 GC07P099936 GC07P099938 GC07P094588 GC07P099940


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PILRB Gene:
The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that
are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor
genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member
of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA),
that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is
thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating
function. (provided by RefSeq, Jun 2013)

GeneCards Summary for PILRB Gene: 
PILRB (paired immunoglobin-like type 2 receptor beta) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with PILRB include williams-beuren syndrome. GO annotations related to this gene include protein binding. An important paralog of this gene is PILRA.

UniProtKB/Swiss-Prot: PILRB_HUMAN, Q9UKJ0
Function: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved
in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that
associates with ITAM-bearing adapter molecules on the cell surface

Gene Wiki entry for PILRB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PILRB gene promoter:
         GR   C/EBPbeta   MAZR   GR-beta   RelA   NF-kappaB   FAC1   E2F-1   GR-alpha   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): PILRB promoter sequence
   Search SABiosciences Chromatin IP Primers for PILRB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PILRB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22.1

PILRB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PILRB gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P099945:  view genomic region     (about GC identifiers)

Start:
99,933,688 bp from pter      End:
99,965,454 bp from pter
Size:
31,767 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 99,293,774-99,325,540     
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for PILRB

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PILRB_HUMAN, Q9UKJ0 (See protein sequence)
Recommended Name: Paired immunoglobulin-like type 2 receptor beta precursor  
Size: 227 amino acids; 25542 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: Q69YF9 Q9HBS0
Alternative splicing: 3 isoforms:  Q9UKJ0-1   Q9UKJ0-2   Q9UKJ0-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PILRB: NX_Q9UKJ0

Explore proteomics data for PILRB at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UKJ0

  • PILRB Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PILRB Protein Expression
    REFSEQ proteins: NP_839956.1  
    ENSEMBL proteins: 
     ENSP00000311153   ENSP00000406563   ENSP00000391748   ENSP00000411261   ENSP00000415775  
     ENSP00000403757   ENSP00000404321   ENSP00000389856   ENSP00000409411   ENSP00000402073  
     ENSP00000416342   ENSP00000408425   ENSP00000410764  

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    Novus Biologicals PILRB Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane NAS10660620

    PILRB for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    VSET: Immunoglobulin superfamily / V-set domain containing

    4 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q9UKJ0

    ProtoNet protein and cluster: Q9UKJ0

    1 Blocks protein domain: IPB013106 Immunoglobulin V-set

    UniProtKB/Swiss-Prot: PILRB_HUMAN, Q9UKJ0
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    PILRB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PILRB_HUMAN, Q9UKJ0
    Function: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved
    in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that
    associates with ITAM-bearing adapter molecules on the cell surface

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI10660620
         
    PILRB for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Pilrb1):
     homeostasis/metabolism  immune system  mortality/aging 

    PILRB for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Pilrb1tm1Pgh for PILRB

       inGenious Targeting Laboratory - Custom generated mouse model solutions for PILRB 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PILRB

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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PILRB 

    miRNA
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for PILRB About                                                                                                See pathways by source

    SuperPathContained pathways About
    1B Cell Receptor Signaling Pathway
    B Cell Receptor Signaling Pathway
    2IL-3 Signaling Pathway
    IL-3 Signaling Pathway


    2 BioSystems Pathways for PILRB
        IL-3 Signaling Pathway
    B Cell Receptor Signaling Pathway



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PILRB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/14 Interacting proteins for PILRB (Q9UKJ02, 3 ENSP000003111534) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABHD16AO958702, 3, ENSP000003792824MINT-62605 MINT-62779 MINT-62703 I2D: score=4 STRING: ENSP00000379282
    ENSG00000236063O958702, 3, ENSP000004069654MINT-62605 MINT-62779 MINT-62703 I2D: score=4 STRING: ENSP00000406965
    ENSG00000206403O958702, 3MINT-62605 MINT-62779 MINT-62703 I2D: score=4 
    ENSG00000224552O958702, 3MINT-62605 MINT-62779 MINT-62703 I2D: score=4 
    ENSG00000230475O958702, 3MINT-62605 MINT-62779 MINT-62703 I2D: score=4 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway TAS10660620
    GO:0007171activation of transmembrane receptor protein tyrosine kinase activity NAS10660620

    PILRB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PILRB

    Search CenterWatch for drugs/clinical trials and news about PILRB

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PILRB gene (3 alternative transcripts): 
    NM_178238.3  NM_013440.3  NM_175047.2  

    Unigene Cluster for PILRB:

    Paired immunoglobin-like type 2 receptor beta
    Hs.632314  [show with all ESTs]
    Unigene Representative Sequence: NR_036569
    18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000473757(uc022ail.1) ENST00000470714 ENST00000310771(uc022aim.1 uc003uum.1 uc003uun.3)
    ENST00000483329 ENST00000444874 ENST00000488972 ENST00000493499 ENST00000472646
    ENST00000452089 ENST00000493091 ENST00000457519 ENST00000448382 ENST00000443526
    ENST00000419749 ENST00000422808 ENST00000438028 ENST00000455145 ENST00000431140

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidPILRB 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PILRB
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    Additional mRNA sequence: 

    AF161081.1 AF217981.1 AJ400845.1 AJ400846.1 AK056412.1 AK298676.1 AL834317.1 AL834336.1 
    BC040122.1 BC050547.1 NR_036569.1 NR_036570.1 

    20 DOTS entries:

    DT.307257  DT.95131666  DT.216327  DT.100649664  DT.216323  DT.92469885  DT.100854198  DT.100859342 
    DT.95144570  DT.99953283  DT.100644563  DT.100678646  DT.100847248  DT.95231891  DT.121100051  DT.95364809 
    DT.102839245  DT.121099942  DT.434832  DT.95144636 

    24/256 AceView cDNA sequences (see all 256):

    BQ029885 AW273346 F28686 AA321993 BU616669 AA860230 AW029066 AL041617 
    AA769325 AI650706 AA476935 NM_175047 AA013428 AA325039 AF217981 AL834336 
    AW780241 BE671796 AI187038 NM_013440 AL040910 AA598667 AL834317 AI624860 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for PILRB (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                                                  -     -     -           -                                             
    SP2:                                            -     -           -                                                         
    SP3:                    -                                                                                                   
    SP4:                                                                                                                        
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for PILRB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PILRB expression in normal human tissues (normalized intensities)      PILRB embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGAGCACCC
    PILRB Expression
    About this image


    PILRB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Spleen (Hematopoietic System)
             splenocytes   
     
     Lung (Respiratory System)
             bronchoalveolar lavage cells   
     
     Epiblast (Early Embryonic Tissues)
             Epiblast Stem Cell line 5

    See PILRB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PILRB

    SOURCE GeneReport for Unigene cluster: Hs.632314
        SABiosciences Custom PCR Arrays for PILRB
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PILRB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for PILRB gene from 1/4 species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pilrb15
    Pilrb21
    paired immunoglobin-like type 2 receptor beta 15
    paired immunoglobin-like type 2 receptor beta 21
    58.49(n)1
    42.31(a)1
      5 (76.82 cM)5
    5458121  NM_001024932.21  NP_001020103.11 
     1378521475 


    ENSEMBL Gene Tree for PILRB (if available)
    TreeFam Gene Tree for PILRB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PILRB gene
    PILRA2  
    1 SIMAP similar gene for PILRB using alignment to 7 protein entries:     PILRB_HUMAN (see all proteins):
    PILRA

    PILRB for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PILRB
    PGOHUM00000233496


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/657 SNPs in PILRB are shown (see all 657)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs286660001,2
    --99936016(+) TGCACA/GCCAGC 2 -- int10--------
    rs744387871,2
    F--99936027(+) CTGGGT/CGACAG 2 -- int11Minor allele frequency- C:0.00NA 2
    rs1852527171,2
    --99936259(+) ATCAAC/TTATTT 2 -- int10--------
    rs1142855491,2
    F--99936268(+) TTTAGG/TACTGA 2 -- int11Minor allele frequency- T:0.07WA 118
    rs1501590451,2
    --99936286(+) TCAGAC/TTCTGC 2 -- int10--------
    rs1905447211,2
    --99936306(+) GGCAGC/TGTAAG 2 -- int10--------
    rs39915641,2
    C,F--99936427(-) GTACCA/GCTTGG 2 -- nc-transcript-variant3Minor allele frequency- G:0.08CSA WA NA 239
    rs39915631,2
    --99936444(-) TTTCCG/AGCTAT 2 -- nc-transcript-variant1Minor allele frequency- A:0.00CSA 1
    rs2016568491,2
    F--99936557(+) TTTGTA/GAGGTG 2 -- int11Minor allele frequency- G:0.01EU 593
    rs1819868081,2
    --99936845(+) GCCACC/GATGCC 2 -- int10--------

    HapMap Linkage Disequilibrium report for PILRB (99933688 - 99965454 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/11 variations for PILRB (see all 11):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2734888CNV Deletion23290073
    esv2734891CNV Deletion23290073
    esv2734890CNV Deletion23290073
    esv270384CNV Insertion20981092
    nsv436898CNV Insertion17901297
    nsv831071CNV Loss17160897
    nsv888775CNV Loss21882294
    nsv888774CNV Gain21882294
    esv26986CNV Gain19812545
    nsv428180CNV Gain18775914

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605342    OMIM disorders: --

    2 diseases for PILRB:    About MalaCards
    williams-beuren syndrome    


    PILRB for disorders           About GeneDecksing


    Export disorders for PILRB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PILRB gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with PILRB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. PILRalpha, a novel immunoreceptor tyrosine-based inhibitory motif- bearing protein, recruits SHP-1 upon tyrosine phosphorylation and is paired with the truncated counterpart PILRbeta. (PubMed id 10660620)1, 2, 3 Mousseau D.D.... Shen S.H. (2000)
    2. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. Comparative analysis of the paired immunoglobulin-like receptor (PILR) locus in six mammalian genomes: duplication, conversion, and the birth of new genes. (PubMed id 16926269)1 Wilson M.D.... Koop B.F. (2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. (PubMed id 14667819)1 Lehner B....Sanderson C.M. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29990 HGNC: 18297 AceView: PILRB Ensembl:ENSG00000121716 euGenes: HUgn29990
    ECgene: PILRB H-InvDB: PILRB

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PILRB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PILRB gene:
    Search GeneIP for patents involving PILRB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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