Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



PIK3R2 Gene

protein-coding   GIFtS: 66
GCID: GC19P018263

Phosphoinositide-3-Kinase, Regulatory Subunit 2 (Beta)

  See PIK3R2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Phosphoinositide-3-Kinase, Regulatory Subunit 2 (Beta)1 2     p852
Phosphatidylinositol 3-Kinase 85 KDa Regulatory Subunit Beta2 3     p85-BETA2
PtdIns-3-Kinase Regulatory Subunit P85-Beta2 3     Phosphatidylinositol 3-Kinase Regulatory Subunit Beta2
PI3-Kinase Subunit P85-Beta2 3     Phosphatidylinositol 3-Kinase, Regulatory Subunit, Polypeptide 2 (P85
Beta)2
PI3K Regulatory Subunit Beta2 3     PI3-Kinase Regulatory Subunit Beta3
MPPH2 5     PtdIns-3-Kinase Regulatory Subunit Beta3
P85B2     

External Ids:    HGNC: 89801   Entrez Gene: 52962   Ensembl: ENSG000001056477   OMIM: 6031575   UniProtKB: O004593   

Export aliases for PIK3R2 gene to outside databases

Previous GC identifers: GC19P018760 GC19P018658 GC19P018108 GC19P018127 GC19P018089 GC19P017828


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for PIK3R2 Gene:
Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar
compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of
a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two
transcript variants, one protein coding and the other non-protein coding, have been found for this gene.
(provided by RefSeq, Dec 2012)

GeneCards Summary for PIK3R2 Gene:
PIK3R2 (phosphoinositide-3-kinase, regulatory subunit 2 (beta)) is a protein-coding gene. Diseases associated with PIK3R2 include megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome, and megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome, somatic. GO annotations related to this gene include receptor tyrosine kinase binding and phosphatidylinositol 3-kinase regulator activity. An important paralog of this gene is PIK3R3.

UniProtKB/Swiss-Prot: P85B_HUMAN, O00459
Function: Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an
adapter, mediating the association of the p110 catalytic unit to the plasma membrane

summary for PIK3R2 Gene:
PI 3-Kinases (phosphoinositide 3-kinases, PI3Ks) are family of lipid kinases capable of phosphorylating the
3'OH of the inositol ring of phosphoinositides. They are responsible for coordinating a diverse range of
cell functions including proliferation, cell survival, degranulation, vesicular trafficking and cell
migration. The PI 3-kinases are grouped into three distinct classes. Class I PI 3-kinases are heteromeric
consisting of a regulatory subunit and a 110 kDA catalytic subunits (3 forms in class 1A : alpha-, beta- and
delta- and one in class 1B : gamma-). PI 3-kinases p110 alpha- and beta- are ubiquitously expressed whilst
p110 delta- expression is associated with leukocytes. Activating mutations in the p110alpha- subunit have
recently been discovered in certain types of cancer cell. Class II PI 3-kinases are large homomeric enzymes
(C2alpha-, beta- and gamma-) that are sensitive to wortmannin (although less sensitive than Class 1 PI
3-kinases) but are resistant to LY 292002. Class III contains just one member, hVps34p, which is thought to
play an important role in both protein sorting and nutrient sensing in concert with the mTOR pathway.

Gene Wiki entry for PIK3R2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the PIK3R2 gene promoter:
         Spz1   Elk-1   SREBP-1c   Egr-1   AP-4   CUTL1   SREBP-1b   CREB   SREBP-1a   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): PIK3R2 promoter sequence
   Search Chromatin IP Primers for PIK3R2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PIK3R2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2-q13.4   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.11

PIK3R2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PIK3R2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P018263:  view genomic region     (about GC identifiers)

Start:
18,263,928 bp from pter      End:
18,281,350 bp from pter
Size:
17,423 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: P85B_HUMAN, O00459 (See protein sequence)
Recommended Name: Phosphatidylinositol 3-kinase regulatory subunit beta  
Size: 728 amino acids; 81545 Da
Subunit: Heterodimer of a regulatory subunit PIK3R2 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD).
Interacts with AXL. Interacts with FLT1 (tyrosine-phosphorylated) and FLT4 (tyrosine-phosphorylated). Interacts
with NYAP1, NYAP2 and MYO16
4 PDB 3D structures from and Proteopedia for PIK3R2:
2KT1 (3D)        2XS6 (3D)        3MTT (3D)        3O5Z (3D)    
Secondary accessions: Q5EAT5 Q9UPH9

Explore the universe of human proteins at neXtProt for PIK3R2: NX_O00459

Explore proteomics data for PIK3R2 at MOPED

Post-translational modifications: 

  • Phosphorylated in response to signaling from activated receptor-type protein kinases. Dephosphorylated by PTPRJ1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PIK3R2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005018.1  
    ENSEMBL proteins: 
     ENSP00000222254   ENSP00000395636   ENSP00000476825  
    Reactome Protein details: O00459

    PIK3R2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for PIK3R2
    OriGene Custom MassSpec
    OriGene Custom Protein Services for PIK3R2
    GenScript Custom Purified and Recombinant Proteins Services for PIK3R2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PIK3R2

     
    Search eBioscience for Proteins for PIK3R2 

     
    antibodies-online proteins for PIK3R2 (2 products) 

     
    antibodies-online peptides for PIK3R2

    PIK3R2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for PIK3R2 (PI 3-Kinase p85 beta)
    Cell Signaling Technology (CST) Antibodies for PIK3R2 
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for PIK3R2
    Novus Biologicals PIK3R2 Antibodies
    Abcam antibodies for PIK3R2
    Cloud-Clone Corp. Antibodies for PIK3R2
    ThermoFisher Antibodies for PIK3R2
    antibodies-online antibodies for PIK3R2 (106 products) 

    PIK3R2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PIK3R2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PIK3R2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PIK3R2
    Cloud-Clone Corp. CLIAs for PIK3R2
    Search eBioscience for ELISAs for PIK3R2 
    antibodies-online kits for PIK3R2 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    SH2D: SH2 domain containing

    5 InterPro protein domains:
     IPR008936 Rho_GTPase_activation_prot
     IPR001720 PI3kinase_P85
     IPR001452 SH3_domain
     IPR000980 SH2
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry O00459

    ProtoNet protein and cluster: O00459

    3 Blocks protein domains:
    IPB000198 RhoGAP domain
    IPB000980 SH2 domain signature
    IPB001720 PI3 kinase P85 regulatory subunit signature


    UniProtKB/Swiss-Prot: P85B_HUMAN, O00459
    Similarity: Belongs to the PI3K p85 subunit family
    Similarity: Contains 1 Rho-GAP domain
    Similarity: Contains 2 SH2 domains
    Similarity: Contains 1 SH3 domain


    Find genes that share domains with PIK3R2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: P85B_HUMAN, O00459
    Function: Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an
    adapter, mediating the association of the p110 catalytic unit to the plasma membrane

         Genatlas biochemistry entry for PIK3R2:
    phosphatidylinositol 3-kinase (p85 beta),regulatory subunit,class IA adaptor molecule associating 110-120kDa
    catalytic subunits,interacting with tyrosine kinase (signal transduction),interacting with inositol
    polyphosphatase 4-phosphatase and inositol polyphosphatase 5-phosphatase,expressed in B and T cells

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16273093
    GO:0016303contributes to 1-phosphatidylinositol-3-kinase activity ISS--
    GO:0030971receptor tyrosine kinase binding IPI10627473
    GO:0035014phosphatidylinositol 3-kinase regulator activity IEA--
         
    Find genes that share ontologies with PIK3R2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for PIK3R2:
     Decreased viability  Increased apoptosis 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Pik3r2):
     cardiovascular system  homeostasis/metabolism  muscle  tumorigenesis 

    Find genes that share phenotypes with PIK3R2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Pik3r2tm1Lca for PIK3R2

       genOway: Develop your customized and physiologically relevant rodent model for PIK3R2

    miRNA
    Products:
        
    miRTarBase miRNAs that target PIK3R2:
    hsa-mir-133a-3p (MIRT021712), hsa-mir-296-3p (MIRT038442), hsa-mir-126-3p (MIRT003894), hsa-mir-30c-5p (MIRT007136), hsa-mir-93-5p (MIRT048832)

    Block miRNA regulation of human, mouse, rat PIK3R2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PIK3R2 (see all 15):
    hsa-miR-30c hsa-miR-4271 hsa-miR-3607-3p hsa-miR-3678-5p hsa-miR-30d hsa-miR-4258 hsa-miR-3667-3p hsa-miR-135b
    SwitchGear 3'UTR luciferase reporter plasmidPIK3R2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PIK3R2
    Predesigned siRNA for gene silencing in human, mouse, rat PIK3R2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PIK3R2

    Clone
    Products:
         
    OriGene clones in human, mouse for PIK3R2 (see all 7)
    OriGene ORF clones in mouse, rat for PIK3R2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PIK3R2 (NM_005027)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PIK3R2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIK3R2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for PIK3R2
    Browse ESI BIO Cell Lines and PureStem Progenitors for PIK3R2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIK3R2

    Flow Cytometry
    Products:
       

     
    eBioscience FlowRNA Probe Sets ( VA4-12612) for PIK3R2 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    nucleus2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005942phosphatidylinositol 3-kinase complex IEA--

    Find genes that share ontologies with PIK3R2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for PIK3R2 About   (see all 167)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1IL-9 Signaling Pathways
    IL-9 Signaling Pathways0.90
    IL-4 Signaling Pathways0.84
    IL-7 Signaling Pathways0.90
    Immune response IL 9 signaling pathway0.42
    IL-21 Signaling Pathways0.90
    Development Thrombopoietin regulated cell processes0.38
    Common Cytokine Receptor Gamma-Chain Family Signaling Pathways0.90
    IL-9 Pathway0.36
    2Immune response Fc epsilon RI pathway
    Immune response Fc epsilon RI pathway0.43
    VEGF signaling pathway0.39
    Immune response BCR pathway0.43
    VEGF - VEGF R2 Signaling Pathways0.35
    Fc epsilon RI signaling pathway0.41
    3Development IGF 1 receptor signaling
    Development IGF RI signaling0.49
    Development IGF 1 receptor signaling0.48
    Signal transduction AKT signaling0.49
    Immune response IL 4 signaling pathway0.39
    4Prolactin Signaling Pathway
    Development Prolactin receptor signaling0.39
    Leptin signaling pathway0.35
    Prolactin Signaling Pathway0.39
    Prolactin signaling pathway0.33
    5Focal adhesion
    Focal adhesion0.65
    Integrin-mediated cell adhesion0.38
    Focal Adhesion0.65
    HGF Pathway0.34


    Find genes that share SuperPaths with PIK3R2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected R&D Systems Pathways for PIK3R2 (see all 12)
        IL-21 Signaling Pathways
    IL-2 Signaling Pathways
    IL-4 Signaling Pathways
    Adipocytokines & Insulin Signaling
    Akt Signaling Pathway

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for PIK3R2 (see all 128)
        UVB-Induced MAPK Signaling
    Fc-GammaR Pathway
    Toll-Like Receptors Pathway
    Molecular Mechanisms of Cancer
    eIF2 Pathway

    1 Cell Signaling Technology (CST) Pathway for PIK3R2
        PI3K / Akt Signaling

    Selected Tocris Bioscience Pathways for PIK3R2 (see all 9)
        Akt Pathway
    Insulin Pathway
    Apoptosis Pathway
    NF-kappaB Pathway
    Toll-like Receptor Pathway

    Selected GeneGo (Thomson Reuters) Pathways for PIK3R2 (see all 63)
        Cytoskeleton remodeling Role of PDGFs in cell migration
    Development FGF-family signaling
    Development CNTF receptor signaling
    Apoptosis and survival Anti-apoptotic action of membrane-bound ESR1
    Development EGFR signaling pathway

    Selected BioSystems Pathways for PIK3R2 (see all 32)
        MicroRNAs in cardiomyocyte hypertrophy
    Focal Adhesion
    Integrin-mediated cell adhesion
    EGFR1 Signaling Pathway
    Insulin Signaling

    Selected Reactome Pathways for PIK3R2 (see all 23)
        Nephrin interactions
    G alpha (12/13) signalling events
    Costimulation by the CD28 family
    Regulation of signaling by CBL
    PI3K/AKT activation

    3 PharmGKB Pathways for PIK3R2
        Anti-diabetic Drug Potassium Channel Inhibitors Pathway, Pharmacodynamics
    EGFR Inhibitor Pathway, Pharmacodynamics
    Sorafenib Pharmacodynamics

    Selected Kegg Pathways  (Kegg details for PIK3R2) (see all 62):
        ErbB signaling pathway
    Ras signaling pathway
    Rap1 signaling pathway
    Chemokine signaling pathway
    HIF-1 signaling pathway

        Pathway & Disease-focused RT2 Profiler PCR Arrays including PIK3R2 (see all 6): 
              mTOR Signaling in human mouse rat
              Insulin Signaling Pathway in human mouse rat
              PI3K-AKT Signaling Pathway in human mouse rat
              EGF / PDGF Signaling Pathway in human mouse rat
              VEGF Signaling in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for PIK3R2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PIK3R2 (O004591, 2, 3 ENSP000002222544) via UniProtKB, MINT, STRING, and/or I2D (see all 391)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERBB2P046261, 2, 3, ENSP000002695714EBI-346930,EBI-641062 MINT-74622 MINT-74623 MINT-74620 MINT-74631 MINT-74621 MINT-61505 MINT-74632 I2D: score=5 STRING: ENSP00000269571
    ERBB3P218601, 2, 3, ENSP000002671014EBI-346930,EBI-720706 MINT-74627 MINT-74618 MINT-61512 MINT-74629 MINT-74637 MINT-61520 MINT-74625 MINT-74638 MINT-61513 MINT-74624 MINT-74636 MINT-74633 MINT-61519 MINT-74628 MINT-74626 MINT-74639 MINT-61516 MINT-74635 MINT-74634 MINT-61517 I2D: score=5 STRING: ENSP00000267101
    EGFRP005331, 2, 3, ENSP000002754934EBI-346930,EBI-297353 MINT-74619 MINT-74630 I2D: score=6 STRING: ENSP00000275493
    GRB2P629931, 3, ENSP000003390074EBI-346930,EBI-401755 I2D: score=5 STRING: ENSP00000339007
    YWHABP319462, 3, ENSP000003001614MINT-50949 I2D: score=3 STRING: ENSP00000300161
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 18):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0006661phosphatidylinositol biosynthetic process TAS--
    GO:0007165signal transduction ----
    GO:0007173epidermal growth factor receptor signaling pathway TAS--
    GO:0007264small GTPase mediated signal transduction TAS--

    Find genes that share ontologies with PIK3R2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
    Selected ApexBio Compounds for PIK3R2 (see all 28)     About this table
    CompoundAction CAS #
    A66highly specific and selective p110alpha inhibitor[1166227-08-2]
    AS-605240Potent and selective inhibitor of PI 3-kinase beta.[648450-29-7]http://www.apexbt.com/search.php?catalog=A5176
    AZD6482Potent and selective inhibitor of PI 3-kinase beta[1173900-33-8]
    BEZ235 (NVP-BEZ235)imidazoquinoline derivative inhibiting both PI3K and mTOR kinases[915019-65-7]
    BKM120small-molecule inhibitor of pan-Class I PI3K[944396-07-0]
    BYL-719selective PI3Kalfa inhibitor[1217486-61-7]
    CAL-101 (Idelalisib, GS-1101)p110delta selective PI3K inhibitor[870281-82-6]
    CAL-130novel PI3K inhibitor. [1431697-74-3]
    CUDC-907dual PI3K and HDAC inhibitor[1339928-25-4]
    CZC24832selective inhibitor of PI3Kgamma[1159824-67-5]

    Compounds for PIK3R2 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    CZC 24832Selective inhibitor of PI 3-Kinase gamma[1159824-67-5]
    QuercetinNon-selective PI 3-kinase inhibitor[117-39-5]
    PI 103 hydrochloride Inhibitor of PI 3-kinase, mTOR and DNA-PK [371935-74-9]
    AS 605240Potent and selective PI 3-kinase gamma (PI3Kgamma) inhibitor[648450-29-7]
    740 Y-PCell-permeable PI 3-kinase activator[1236188-16-1]

    1 DrugBank Compound for PIK3R2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    IsoproterenolEpinephrine Isopropyl Homolog (see all 14)7683-59-2targetagonist15985706 15527548 15381832 15618457 15110780

    3 Novoseek inferred chemical compound relationships for PIK3R2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    phosphatidylinositol 73.2 15 8388374 (3), 7961856 (3), 9054447 (3), 9819398 (1) (see all 7)
    phosphoinositide 55.5 4 14504291 (3)
    threonine 25.9 1 8388374 (1)



    Find genes that share compounds with PIK3R2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for PIK3R2 gene: 
    NM_005027.3  

    Unigene Cluster for PIK3R2:

    Phosphoinositide-3-kinase, regulatory subunit 2 (beta)
    Hs.371344  [show with all ESTs]
    Unigene Representative Sequence: NR_073517
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000222254(uc002nia.1 uc002nib.1 uc010ebi.1) ENST00000426902
    ENST00000474310 ENST00000600533 ENST00000464016 ENST00000459743
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PIK3R2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PIK3R2 (see all 15):
    hsa-miR-30c hsa-miR-4271 hsa-miR-3607-3p hsa-miR-3678-5p hsa-miR-30d hsa-miR-4258 hsa-miR-3667-3p hsa-miR-135b
    SwitchGear 3'UTR luciferase reporter plasmidPIK3R2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PIK3R2
    Predesigned siRNA for gene silencing in human, mouse, rat PIK3R2
    Clone
    Products:
         
    OriGene clones in human, mouse for PIK3R2 (see all 7)
    OriGene ORF clones in mouse, rat for PIK3R2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PIK3R2 (NM_005027)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PIK3R2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIK3R2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PIK3R2
    OriGene qSTAR qPCR primer pairs in human, mouse for PIK3R2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PIK3R2
      QuantiTect SYBR Green Assays in human, mouse, rat PIK3R2
      QuantiFast Probe-based Assays in human, mouse, rat PIK3R2
    Flow Cytometry
    Products:
       

     
    eBioscience FlowRNA Probe Sets ( VA4-12612) for PIK3R2 

    Additional mRNA sequence: 

    BC011917.2 BC014170.2 BC070082.1 BC090249.1 NR_073517.1 X80907.1 

    10 DOTS entries:

    DT.100786670  DT.92448454  DT.112688  DT.95119443  DT.120809034  DT.100786666  DT.100829705  DT.121450173 
    DT.40303890  DT.95119465 

    Selected AceView cDNA sequences (see all 288):

    BU190893 BQ677884 AI369452 AW014221 BM550201 BM908555 BC014170 AW168551 
    BQ880915 BM468924 BQ676382 BM910667 AA342109 BM263834 BQ881548 BQ680415 
    BG760335 AI870794 AW298465 CA952441 NM_005027 BM551554 BQ069629 BX417585 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    PIK3R2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGGTTTTG
    PIK3R2 Expression
    About this image

    PIK3R2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PIK3R2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.371344
        Pathway & Disease-focused RT2 Profiler PCR Arrays including PIK3R2 (see all 6): 
              mTOR Signaling in human mouse rat
              Insulin Signaling Pathway in human mouse rat
              PI3K-AKT Signaling Pathway in human mouse rat
              EGF / PDGF Signaling Pathway in human mouse rat
              VEGF Signaling in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for PIK3R2
    OriGene qSTAR qPCR primer pairs in human, mouse for PIK3R2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PIK3R2
    QuantiTect SYBR Green Assays in human, mouse, rat PIK3R2
    QuantiFast Probe-based Assays in human, mouse, rat PIK3R2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIK3R2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for PIK3R2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pik3r21 , 5 phosphatidylinositol 3-kinase, regulatory subunit, more1, 5 84.15(n)1
    89.59(a)1
      8 (34.15 cM)5
    187091  NM_008841.21  NP_032867.21 
     707681765 
    chicken
    (Gallus gallus)
    Aves PIK3R21 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 73.12(n)
    74.36(a)
      771142  XM_001233340.3  XP_001233341.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    76(a)
    70(a)
    many ↔ many
    many ↔ many
    AAWZ02040215(987-6935)
    AAWZ02041587(1090-4649)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia pik3r21 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 62.25(n)
    64.32(a)
      100497001  XM_002934809.2  XP_002934855.2 
    zebrafish
    (Danio rerio)
    Actinopterygii pik3r21 phosphoinositide-3-kinase, regulatory subunit, polypeptide more 64.94(n)
    63.98(a)
      404211  NM_212822.1  NP_997987.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Pi3K21B6
    Pi3K21B
    31(a)
    1 → many
    2L(297880-305233)
    worm
    (Caenorhabditis elegans)
    Secernentea aap-16
    Protein AAP-1 (aap-1) mRNA, complete cds
    24(a)
    1 → many
    I(5107843-5110164) WBGene00000001


    ENSEMBL Gene Tree for PIK3R2 (if available)
    TreeFam Gene Tree for PIK3R2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for PIK3R2 gene
    PIK3R32  PIK3R12  ENSG000002681732  
    4 SIMAP similar genes for PIK3R2 using alignment to 6 protein entries:     P85B_HUMAN (see all proteins):
    DKFZp686P05226    PIK3R1    PIK3R3    DKFZp686F1293

    Find genes that share paralogs with PIK3R2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for PIK3R2 (see all 453)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0692624
    Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)4--see VAR_0692622 G R mis40--------
    rs571320351,2
    C--17839707(+) AAAAAAA/-TTAGC 2 -- int11Minor allele frequency- -:0.00NA 2
    rs1884032761,2
    --18193512(+) GTTTCC/TTTGTG 2 -- us2k10--------
    rs1924150871,2
    --18193742(+) TGGGCA/GTTGTC 2 -- us2k10--------
    rs1843023601,2
    --18193758(+) GGGAGC/GTTGAA 2 -- us2k10--------
    rs586951501,2
    C--18193875(+) GCCCAA/C/TTCTGC 2 -- us2k12CSA WA 119
    rs1505555221,2
    --18193924(+) TGGAGC/GGTAGA 2 -- us2k10--------
    rs754307181,2
    C,F--18194089(+) CATGGC/TTCAAA 2 -- us2k12Minor allele frequency- T:0.06CSA WA 120
    rs129772161,2
    C,F--18194174(+) AGCCTC/GCTGCT 2 -- us2k13Minor allele frequency- G:0.33NA 6
    rs1167559541,2
    C,F--18194296(+) CTGTAA/GCCCAG 2 -- us2k11Minor allele frequency- G:0.03WA 118

    HapMap Linkage Disequilibrium report for PIK3R2 (18263928 - 18281350 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for PIK3R2 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2677454CNV Deletion23128226
    dgv3775n71CNV Loss21882294
    nsv911256CNV Loss21882294
    nsv911254CNV Loss21882294
    nsv833773CNV Loss17160897
    dgv3773n71CNV Loss21882294
    nsv833774CNV Loss17160897
    dgv3772n71CNV Loss21882294
    dgv3776n71CNV Loss21882294
    dgv3771n71CNV Loss21882294

    Human Gene Mutation Database (HGMD): PIK3R2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PIK3R2
    DNA2.0 Custom Variant and Variant Library Synthesis for PIK3R2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 603157   
    OMIM disorders: 603387  
    UniProtKB/Swiss-Prot: P85B_HUMAN, O00459
  • Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH) [MIM:603387]: A syndrome
    characterized by megalencephaly, hydrocephalus, and polymicrogyria; polydactyly may also be seen. There is
    considerable phenotypic similarity between this disorder and the megalencephaly-capillary malformation syndrome.
    Note=The disease is caused by mutations affecting the gene represented in this entry

  • 4 diseases for PIK3R2:    
    About MalaCards
    megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome    megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome, somatic    megalencephaly    hydrocephalus


    Find genes that share disorders with PIK3R2           About GenesLikeMe

    1 Novoseek inferred disease relationship for PIK3R2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    colon carcinoma 39.2 2 9822674 (1), 11042696 (1)

    Genetic Association Database (GAD): PIK3R2
    Human Genome Epidemiology (HuGE) Navigator: PIK3R2 (4 documents)

    Export disorders for PIK3R2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for PIK3R2 gene, integrated from 10 sources (see all 154):
    (articles sorted by number of sources associating them with PIK3R2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Chromosomal localization of human p85 alpha, a subunit of phosphatidylinositol 3-kinase, and its homologue p85 beta. (PubMed id 1314371)1, 2, 3 Volinia S.... Waterfield M.D. (Oncogene 1992)
    2. De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes. (PubMed id 22729224)1, 2 Riviere J.B.... Dobyns W.B. (Nat. Genet. 2012)
    3. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)1, 4 Lu Y....Boer J.M. (J. Lipid Res. 2008)
    4. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. An oncogenic fusion product of the phosphatidylinositol 3-kinase p85beta subunit and HUMORF8, a putative deubiquitinating enzyme. (PubMed id 9582025)1, 2 Janssen J.W.G.... Schulz A.S. (Oncogene 1998)
    7. Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site. (PubMed id 9178760)1, 2 Braunger J.... Janssen J.W. (Oncogene 1997)
    8. p85beta phosphoinositide 3-kinase regulates CD28 coreceptor function. (PubMed id 19190244)1, 9 AlcA!zar I....Carrera A.C. (Blood 2009)
    9. Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system. (PubMed id 1334406)1, 9 Gout I....Waterfield M.D. (Biochem. J. 1992)
    10. Formation of signal transfer complexes between stem cell and platelet-derived growth factor receptors and SH2 domain proteins in vitro. (PubMed id 7537096)1, 9 Herbst R....Ullrich A. (Biochemistry 1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 5296 HGNC: 8980 AceView: PIK3R2 Ensembl:ENSG00000105647 euGenes: HUgn5296
    ECgene: PIK3R2 Kegg: 5296 H-InvDB: PIK3R2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for PIK3R2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for PIK3R2 gene:
    Search GeneIP for patents involving PIK3R2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Antibodies for PIK3R2 (PI 3-Kinase p85 beta)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for PIK3R2  
     OriGene qPCR primer pairs and template standards for PIK3R2   OriGene Protein Over-expression Lysate for PIK3R2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for PIK3R2  
     OriGene qSTAR qPCR primer pairs in human, mouse for PIK3R2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for PIK3R2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PIK3R2   OriGene Custom Protein Services for PIK3R2  

     
     
     Block miRNA regulation of human, mouse, rat PIK3R2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PIK3R2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PIK3R2 Predesigned siRNA for gene silencing in human, mouse, rat PIK3R2
     QuantiFast Probe-based Assays in human, mouse, rat PIK3R2 QuantiTect SYBR Green Assays in human, mouse, rat PIK3R2
     PCR Arrays including human, mouse, rat PIK3R2 Search Chromatin IP Primers for PIK3R2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PIK3R2  GeneGlobe Interaction Network for PIK3R2
     Regulatory tfbs in PIK3R2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for PIK3R2 GenScript cDNA clones with any tag delivered in your preferred vector for PIK3R2
     GenScript Custom Assay Services for PIK3R2 GenScript Custom overexpressing Cell Line Services for PIK3R2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Antibodies & Assays for PIK3R2 

     Tocris compounds for PIK3R2
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     PIK3R2 antibodies
     Antibodies for PIK3R2
     See all of Abcam's Antibodies, Kits and Proteins for PIK3R2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for PIK3R2
     Antibodies for PIK3R2
     ELISAs for PIK3R2
     CLIAs for PIK3R2



     Browse ESI BIO Cell Lines and PureStem Progenitors for PIK3R2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIK3R2
     SwitchGear 3'UTR luciferase reporter plasmids for PIK3R2
     SwitchGear Promoter luciferase reporter plasmids for PIK3R2
     ThermoFisher Antibodies for PIK3R2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIK3R2
     ApexBio compounds for PIK3R2
     Search Addgene for plasmids for PIK3R2
      Search eBioscience for proteins for PIK3R2
      Search eBioscience for elisas for PIK3R2
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for PIK3R2
     antibodies-online antibodies for PIK3R2 (106 products)
     antibodies-online kits for PIK3R2 (8 products)
     antibodies-online peptides for PIK3R2
     antibodies-online proteins for PIK3R2 (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      PIK3R2 gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4