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Aliases for PIK3CG Gene

Aliases for PIK3CG Gene

  • Phosphatidylinositol-4,5-Bisphosphate 3-Kinase, Catalytic Subunit Gamma 2 3
  • Serine/Threonine Protein Kinase PIK3CG 3 4
  • PtdIns-3-Kinase Subunit P110-Gamma 3 4
  • PtdIns-3-Kinase Subunit Gamma 3 4
  • PI3-Kinase Subunit Gamma 3 4
  • EC 2.7.1.153 4 63
  • PI3Kgamma 3 4
  • P110gamma 3 4
  • P120-PI3K 3 4
  • Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform 3
  • Phosphatidylinositol-4,5-Bisphosphate 3-Kinase 110 KDa Catalytic Subunit Gamma 3
  • Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform 3
  • Phosphatidylinositol 4,5-Bisphosphate 3-Kinase 110 KDa Catalytic Subunit Gamma 4
  • Phosphoinositide-3-Kinase, Catalytic, Gamma Polypeptide 2
  • Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide 4
  • Phosphatidylinositol 3-Kinase Catalytic 110-KD Gamma 3
  • Phosphoinositide-3-Kinase Gamma Catalytic Subunit 3
  • Phosphatidylinositol 3 Kinase Gamma, P110 Gamma 3
  • 1-Phosphatidylinositol 3-Kinase 3
  • EC 2.7.11.1 4
  • PI3K-Gamma 4
  • EC 2.7.1 63
  • PI3CG 3
  • PI3K 3
  • PIK3 3

External Ids for PIK3CG Gene

Previous GeneCards Identifiers for PIK3CG Gene

  • GC07P104989
  • GC07P106052
  • GC07P106066
  • GC07P106099
  • GC07P106292
  • GC07P106505
  • GC07P100864

Summaries for PIK3CG Gene

Entrez Gene Summary for PIK3CG Gene

  • This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]

GeneCards Summary for PIK3CG Gene

PIK3CG (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase, Catalytic Subunit Gamma) is a Protein Coding gene. Diseases associated with PIK3CG include breast cancer. Among its related pathways are PI3K-Akt signaling pathway and Glioma. GO annotations related to this gene include protein serine/threonine kinase activity and ephrin receptor binding. An important paralog of this gene is PIK3CB.

UniProtKB/Swiss-Prot for PIK3CG Gene

  • Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Links G-protein coupled receptor activation to PIP3 production. Involved in immune, inflammatory and allergic responses. Modulates leukocyte chemotaxis to inflammatory sites and in response to chemoattractant agents. May control leukocyte polarization and migration by regulating the spatial accumulation of PIP3 and by regulating the organization of F-actin formation and integrin-based adhesion at the leading edge. Controls motility of dendritic cells. Together with PIK3CD is involved in natural killer (NK) cell development and migration towards the sites of inflammation. Participates in T-lymphocyte migration. Regulates T-lymphocyte proliferation and cytokine production. Together with PIK3CD participates in T-lymphocyte development. Required for B-lymphocyte development and signaling. Together with PIK3CD participates in neutrophil respiratory burst. Together with PIK3CD is involved in neutrophil chemotaxis and extravasation. Together with PIK3CB promotes platelet aggregation and thrombosis. Regulates alpha-IIb/beta-3 integrins (ITGA2B/ ITGB3) adhesive function in platelets downstream of P2Y12 through a lipid kinase activity-independent mechanism. May have also a lipid kinase activity-dependent function in platelet aggregation. Involved in endothelial progenitor cell migration. Negative regulator of cardiac contractility. Modulates cardiac contractility by anchoring protein kinase A (PKA) and PDE3B activation, reducing cAMP levels. Regulates cardiac contractility also by promoting beta-adrenergic receptor internalization by binding to ADRBK1 and by non-muscle tropomyosin phosphorylation. Also has serine/threonine protein kinase activity: both lipid and protein kinase activities are required for beta-adrenergic receptor endocytosis. May also have a scaffolding role in modulating cardiac contractility. Contributes to cardiac hypertrophy under pathological stress. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Tocris Summary for PIK3CG Gene

  • PI 3-Kinases (phosphoinositide 3-kinases, PI3Ks) are family of lipid kinases capable of phosphorylating the 3'OH of the inositol ring of phosphoinositides. They are responsible for coordinating a diverse range of cell functions including proliferation, cell survival, degranulation, vesicular trafficking and cell migration. The PI 3-kinases are grouped into three distinct classes. Class I PI 3-kinases are heteromeric consisting of a regulatory subunit and a 110 kDA catalytic subunits (3 forms in class 1A : alpha-, beta- and delta- and one in class 1B : gamma-). PI 3-kinases p110 alpha- and beta- are ubiquitously expressed whilst p110 delta- expression is associated with leukocytes. Activating mutations in the p110alpha- subunit have recently been discovered in certain types of cancer cell. Class II PI 3-kinases are large homomeric enzymes (C2alpha-, beta- and gamma-) that are sensitive to wortmannin (although less sensitive than Class 1 PI 3-kinases) but are resistant to LY 292002. Class III contains just one member, hVps34p, which is thought to play an important role in both protein sorting and nutrient sensing in concert with the mTOR pathway.

Gene Wiki entry for PIK3CG Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PIK3CG Gene

Genomics for PIK3CG Gene

Regulatory Elements for PIK3CG Gene

Genomic Location for PIK3CG Gene

Start:
106,865,278 bp from pter
End:
106,908,978 bp from pter
Size:
43,701 bases
Orientation:
Plus strand

Genomic View for PIK3CG Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PIK3CG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PIK3CG Gene

Proteins for PIK3CG Gene

  • Protein details for PIK3CG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P48736-PK3CG_HUMAN
    Recommended name:
    Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
    Protein Accession:
    P48736
    Secondary Accessions:
    • A4D0Q6
    • Q8IV23
    • Q9BZC8

    Protein attributes for PIK3CG Gene

    Size:
    1102 amino acids
    Molecular mass:
    126454 Da
    Quaternary structure:
    • Heterodimer of a catalytic subunit PIK3CG and a PIK3R5 or PIK3R6 regulatory subunit. Interacts with ADRBK1 through the PIK helical domain. Interaction with ADRBK1 is required for targeting to agonist-occupied receptor. Interacts with PDE3B (By similarity). Interacts with TPM2. Interacts with EPHA8; regulates integrin-mediated cell adhesion to substrate. Interacts with HRAS; the interaction is required for membrane recruitment and beta-gamma G protein dimer-dependent activation of the PI3K gamma complex PIK3CG:PIK3R6 (By similarity).
    Miscellaneous:
    • Candidate target in therapy for inflammatory diseases. Selective inhibitors and protein ablation are anti-inflammatory in multiple disease models such as asthma, rheumatoid arthritis, allergy, systemic lupus erythematosus, airway inflammation, lung injury and pancreatitis (PubMed:18278175).

    Three dimensional structures from OCA and Proteopedia for PIK3CG Gene

neXtProt entry for PIK3CG Gene

Proteomics data for PIK3CG Gene at MOPED

Selected DME Specific Peptides for PIK3CG Gene

Post-translational modifications for PIK3CG Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PIK3CG Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Domains for PIK3CG Gene

Suggested Antigen Peptide Sequences for PIK3CG Gene

Graphical View of Domain Structure for InterPro Entry

P48736

UniProtKB/Swiss-Prot:

PK3CG_HUMAN :
  • P48736
Domain:
  • Contains 1 C2 PI3K-type domain.
  • Contains 1 PI3K-ABD domain.
  • Contains 1 PI3K-RBD domain.
  • Contains 1 PI3K/PI4K domain.
  • Contains 1 PIK helical domain.
Family:
  • Belongs to the PI3/PI4-kinase family.
genes like me logo Genes that share domains with PIK3CG: view

Function for PIK3CG Gene

Molecular function for PIK3CG Gene

UniProtKB/Swiss-Prot CatalyticActivity: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate
UniProtKB/Swiss-Prot CatalyticActivity: ATP + a protein = ADP + a phosphoprotein
UniProtKB/Swiss-Prot EnzymeRegulation: Activated by both the alpha and the beta-gamma G proteins following stimulation of G protein-coupled receptors (GPCRs). Activation by GPCRs is assisted by the regulatory subunits (PIK3R5 or PIK3R6) leading to the translocation from the cytosol to the plasma membrane and to kinase activation. Inhibited by AS-604850 and AS-605240.
UniProtKB/Swiss-Prot Function: Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Links G-protein coupled receptor activation to PIP3 production. Involved in immune, inflammatory and allergic responses. Modulates leukocyte chemotaxis to inflammatory sites and in response to chemoattractant agents. May control leukocyte polarization and migration by regulating the spatial accumulation of PIP3 and by regulating the organization of F-actin formation and integrin-based adhesion at the leading edge. Controls motility of dendritic cells. Together with PIK3CD is involved in natural killer (NK) cell development and migration towards the sites of inflammation. Participates in T-lymphocyte migration. Regulates T-lymphocyte proliferation and cytokine production. Together with PIK3CD participates in T-lymphocyte development. Required for B-lymphocyte development and signaling. Together with PIK3CD participates in neutrophil respiratory burst. Together with PIK3CD is involved in neutrophil chemotaxis and extravasation. Together with PIK3CB promotes platelet aggregation and thrombosis. Regulates alpha-IIb/beta-3 integrins (ITGA2B/ ITGB3) adhesive function in platelets downstream of P2Y12 through a lipid kinase activity-independent mechanism. May have also a lipid kinase activity-dependent function in platelet aggregation. Involved in endothelial progenitor cell migration. Negative regulator of cardiac contractility. Modulates cardiac contractility by anchoring protein kinase A (PKA) and PDE3B activation, reducing cAMP levels. Regulates cardiac contractility also by promoting beta-adrenergic receptor internalization by binding to ADRBK1 and by non-muscle tropomyosin phosphorylation. Also has serine/threonine protein kinase activity: both lipid and protein kinase activities are required for beta-adrenergic receptor endocytosis. May also have a scaffolding role in modulating cardiac contractility. Contributes to cardiac hypertrophy under pathological stress. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Enzyme Numbers (IUBMB) for PIK3CG Gene

Gene Ontology (GO) - Molecular Function for PIK3CG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity TAS 19376709
GO:0004674 protein serine/threonine kinase activity IEA --
GO:0005488 binding --
GO:0005515 protein binding IPI 12507995
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with PIK3CG: view
genes like me logo Genes that share phenotypes with PIK3CG: view

Animal Models for PIK3CG Gene

MGI Knock Outs for PIK3CG:

miRNA for PIK3CG Gene

miRTarBase miRNAs that target PIK3CG

No data available for Transcription Factor Targeting and HOMER Transcription for PIK3CG Gene

Localization for PIK3CG Gene

Subcellular locations from UniProtKB/Swiss-Prot for PIK3CG Gene

Cytoplasm. Cell membrane.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PIK3CG Gene COMPARTMENTS Subcellular localization image for PIK3CG gene
Compartment Confidence
cytosol 5
plasma membrane 5
mitochondrion 2
cytoskeleton 1
endoplasmic reticulum 1
extracellular 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for PIK3CG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 12507995
GO:0005829 cytosol TAS --
GO:0005886 plasma membrane IBA --
GO:0005942 phosphatidylinositol 3-kinase complex --
GO:0005944 phosphatidylinositol 3-kinase complex, class IB IDA 12507995
genes like me logo Genes that share ontologies with PIK3CG: view

Pathways for PIK3CG Gene

genes like me logo Genes that share pathways with PIK3CG: view

Pathways by source for PIK3CG Gene

UniProtKB/Swiss-Prot P48736-PK3CG_HUMAN

  • Pathway: Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis

Gene Ontology (GO) - Biological Process for PIK3CG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001525 angiogenesis IEA --
GO:0001816 cytokine production TAS 19075988
GO:0002250 adaptive immune response TAS 17290298
GO:0002407 dendritic cell chemotaxis TAS 18278175
GO:0002675 positive regulation of acute inflammatory response IEA --
genes like me logo Genes that share ontologies with PIK3CG: view

Compounds for PIK3CG Gene

(5) Tocris Compounds for PIK3CG Gene

Compound Action Cas Number
740 Y-P Cell-permeable PI 3-kinase activator [1236188-16-1]
PF 05212384 Potent and selective dual PI 3-K/mTOR inhibitor [1197160-78-3]
PI 103 hydrochloride Inhibitor of PI 3-kinase, mTOR and DNA-PK [371935-79-4]
PI 828 PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130) [942289-87-4]
Quercetin Non-selective PI 3-kinase inhibitor [117-39-5]

(382) HMDB Compounds for PIK3CG Gene

Compound Synonyms Cas Number PubMed IDs
1-Phosphatidyl-D-myo-inositol
  • 1-Phosphatidyl-1D-myo-inositol
Not Available
Adenosine triphosphate
  • 5'-(tetrahydrogen triphosphate) Adenosine
56-65-5
ADP
  • adenosindiphosphorsaeure
58-64-0
Phosphatidylinositol-3,4,5-trisphosphate
  • Phosphatidylinositol-3,4,5-trisphosphate
Not Available
PI(16:0/16:0)
  • Phosphatidylinositol(32:0)
Not Available

(126) Novoseek inferred chemical compound relationships for PIK3CG Gene

Compound -log(P) Hits PubMed IDs
ly294002 98.3 214
wortmannin 96.5 186
phosphatidylinositol 96.3 209
phosphoinositide 92.4 107
pd 98,059 90.4 107
genes like me logo Genes that share compounds with PIK3CG: view

Transcripts for PIK3CG Gene

Unigene Clusters for PIK3CG Gene

Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PIK3CG Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c
SP1: -
SP2: - -
SP3:

Relevant External Links for PIK3CG Gene

GeneLoc Exon Structure for
PIK3CG
ECgene alternative splicing isoforms for
PIK3CG

Expression for PIK3CG Gene

mRNA expression in normal human tissues for PIK3CG Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for PIK3CG Gene

This gene is overexpressed in Whole Blood (20.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for PIK3CG Gene

SOURCE GeneReport for Unigene cluster for PIK3CG Gene Hs.32942

mRNA Expression by UniProt/SwissProt for PIK3CG Gene

P48736-PK3CG_HUMAN
Tissue specificity: Pancreas, skeletal muscle, liver and heart.
genes like me logo Genes that share expressions with PIK3CG: view

Orthologs for PIK3CG Gene

This gene was present in the common ancestor of animals.

Orthologs for PIK3CG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PIK3CG 35
  • 99.55 (n)
  • 99.82 (a)
PIK3CG 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia PIK3CG 35
  • 89.97 (n)
  • 94.98 (a)
PIK3CG 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia PIK3CG 35
  • 88.32 (n)
  • 92.29 (a)
PIK3CG 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Pik3cg 35
  • 86.99 (n)
  • 94.1 (a)
Pik3cg 16
Pik3cg 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia PIK3CG 36
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia PIK3CG 36
  • 74 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Pik3cg 35
  • 86.6 (n)
  • 93.65 (a)
chicken
(Gallus gallus)
Aves PIK3CG 35
  • 75.59 (n)
  • 84.75 (a)
PIK3CG 36
  • 85 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia PIK3CG 36
  • 81 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.34757 35
tropical clawed frog
(Silurana tropicalis)
Amphibia pik3cg 35
  • 71.72 (n)
  • 79.76 (a)
Str.8580 35
zebrafish
(Danio rerio)
Actinopterygii pik3cg 35
  • 54.55 (n)
  • 47.84 (a)
pik3cg 36
  • 72 (a)
OneToOne
wufb15d07 35
worm
(Caenorhabditis elegans)
Secernentea age-1 36
  • 24 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.5268 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 41 (a)
OneToOne
Species with no ortholog for PIK3CG:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PIK3CG Gene

ENSEMBL:
Gene Tree for PIK3CG (if available)
TreeFam:
Gene Tree for PIK3CG (if available)

Paralogs for PIK3CG Gene

Paralogs for PIK3CG Gene

Selected SIMAP similar genes for PIK3CG Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with PIK3CG: view

Variants for PIK3CG Gene

Sequence variations from dbSNP and Humsavar for PIK3CG Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs718207 -- 106,870,903(+) TAGAA(A/T)AATTA intron-variant
rs849367 -- 106,875,709(+) tatgg(A/C)tatac intron-variant
rs849368 -- 106,876,040(+) ctccc(A/G)agtag intron-variant
rs849369 -- 106,876,270(+) tcact(A/G)ttgtt intron-variant
rs849370 -- 106,879,498(-) CACAT(A/G)TTCCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PIK3CG Gene

Variant ID Type Subtype PubMed ID
nsv507407 CNV Insertion 20534489

Relevant External Links for PIK3CG Gene

HapMap Linkage Disequilibrium report
PIK3CG
Human Gene Mutation Database (HGMD)
PIK3CG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PIK3CG Gene

Disorders for PIK3CG Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for PIK3CG Gene including...

Search for PIK3CG Gene in MalaCards »

(90) Novoseek inferred disease relationships for PIK3CG Gene

Disease -log(P) Hits PubMed IDs
tumors 60.1 135
cancer 59.2 136
prostate cancer 47.4 43
glioblastoma 43.5 16
insulin resistance 42.3 23

Relevant External Links for PIK3CG

Genetic Association Database (GAD)
PIK3CG
Human Genome Epidemiology (HuGE) Navigator
PIK3CG
genes like me logo Genes that share disorders with PIK3CG: view

No data available for UniProtKB/Swiss-Prot for PIK3CG Gene

Publications for PIK3CG Gene

  1. Protein kinase activity of phosphoinositide 3-kinase regulates beta- adrenergic receptor endocytosis. (PMID: 16094730) Naga Prasad S.V. … Rockman H.A. (Nat. Cell Biol. 2005) 3 4 23
  2. p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma. (PMID: 15797027) Suire S. … Stephens L. (Curr. Biol. 2005) 3 4 23
  3. Targeting phosphoinositide 3-kinase gamma to fight inflammation and more. (PMID: 18278175) Barberis L. … Hirsch E. (Thromb. Haemost. 2008) 3 4 23
  4. Cardiac regulation by phosphoinositide 3-kinases and PTEN. (PMID: 19147653) Oudit G.Y. … Penninger J.M. (Cardiovasc. Res. 2009) 3 4 23
  5. Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer. (PMID: 18652687) Heinonen H. … Monni O. (BMC Genomics 2008) 3 23

Products for PIK3CG Gene

  • antibodies-online peptides for PIK3CG
  • antibodies-online antibodies for PIK3CG
  • antibodies-online kits for PIK3CG

Sources for PIK3CG Gene

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