Aliases for PIGQ Gene
External Ids for PIGQ Gene
Previous GeneCards Identifiers for PIGQ Gene
This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
GeneCards Summary for PIGQ Gene
PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis Class Q) is a Protein Coding gene. Diseases associated with PIGQ include ohtahara syndrome and acute contagious conjunctivitis. Among its related pathways are Metabolism and Transport to the Golgi and subsequent modification. GO annotations related to this gene include phosphatidylinositol N-acetylglucosaminyltransferase activity.
UniProtKB/Swiss-Prot for PIGQ Gene
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.