Aliases for PIGL Gene
External Ids for PIGL Gene
Previous GeneCards Identifiers for PIGL Gene
This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum. [provided by RefSeq, Jul 2008]
GeneCards Summary for PIGL Gene
PIGL (Phosphatidylinositol Glycan Anchor Biosynthesis, Class L) is a Protein Coding gene. Diseases associated with PIGL include chime syndrome and hyperphosphatasia-intellectual disability syndrome. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism. GO annotations related to this gene include N-acetylglucosaminylphosphatidylinositol deacetylase activity.
UniProtKB/Swiss-Prot for PIGL Gene
Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol