Aliases for PIGF Gene
External Ids for PIGF Gene
Previous GeneCards Identifiers for PIGF Gene
This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for PIGF Gene
PIGF (Phosphatidylinositol Glycan Anchor Biosynthesis Class F) is a Protein Coding gene. Diseases associated with PIGF include Pre-Eclampsia and Preeclampsia/Eclampsia 1. Among its related pathways are VEGF Signaling and Diurnally regulated genes with circadian orthologs. GO annotations related to this gene include ethanolaminephosphotransferase activity.
UniProtKB/Swiss-Prot for PIGF Gene
Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI.