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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PIGC Gene

protein-coding   GIFtS: 55
GCID: GC01M172339

Phosphatidylinositol Glycan Anchor Biosynthesis, Class C

(Previous names: phosphatidylinositol glycan, class C)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Phosphatidylinositol Glycan Anchor Biosynthesis, Class C1 2     Phosphatidylinositol N-Acetylglucosaminyltransferase1
GPI22 3 5     Phosphatidylinositol N-Acetylglucosaminyltransferase Subunit C2
Phosphatidylinositol-Glycan Biosynthesis Class C Protein2 3     Phosphatidylinositol-Glycan Biosynthesis, Class C Protein2
PIG-C2 3     EC 2.4.1.1983
Phosphatidylinositol Glycan, Class C1     

External Ids:    HGNC: 89601   Entrez Gene: 52792   Ensembl: ENSG000001358457   OMIM: 6017305   UniProtKB: Q925353   

Export aliases for PIGC gene to outside databases

Previous GC identifers: GC01M169974 GC01M168039 GC01M168991 GC01M169649 GC01M169142 GC01M170628 GC01M170677 GC01M143634


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PIGC Gene:
This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol
(GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to
anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc)
transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic
reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A
pseudogene on chromosome 11 has also been characterized. (provided by RefSeq, Jul 2008)

GeneCards Summary for PIGC Gene: 
PIGC (phosphatidylinositol glycan anchor biosynthesis, class C) is a protein-coding gene. Diseases associated with PIGC include lassa fever, and among its related super-pathways are Post-translational modification: synthesis of GPI-anchored proteins and Post-translational protein modification. GO annotations related to this gene include catalytic activity and phosphatidylinositol N-acetylglucosaminyltransferase activity.

UniProtKB/Swiss-Prot: PIGC_HUMAN, Q92535
Function: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to
phosphatidylinositol, the first step of GPI biosynthesis

Gene Wiki entry for PIGC Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PIGC gene promoter:
         AML1a   POU3F1   SREBP-1c   CUTL1   STAT5A   E47   SREBP-1b   SREBP-1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPIGC promoter sequence
   Search SABiosciences Chromatin IP Primers for PIGC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PIGC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23-q25   Ensembl cytogenetic band:  1q24.3   HGNC cytogenetic band: 1q23-q25

PIGC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PIGC gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M172339:  view genomic region     (about GC identifiers)

Start:
172,339,329 bp from pter      End:
172,413,230 bp from pter
Size:
73,902 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PIGC_HUMAN, Q92535 (See protein sequence)
Recommended Name: Phosphatidylinositol N-acetylglucosaminyltransferase subunit C  
Size: 297 amino acids; 33583 Da
Subunit: Associates with PIGA, PIGH, PIGP, PIGQ and DPM2. The latter is not essential for activity
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (Potential)
Secondary accessions: O14491

Explore the universe of human proteins at neXtProt for PIGC: NX_Q92535

Explore proteomics data for PIGC at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q92535

  • PIGC Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PIGC Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_002633.1  NP_714969.1  

    ENSEMBL proteins: 
     ENSP00000356701   ENSP00000356702   ENSP00000258324  
    Reactome Protein details: Q92535
    Human Recombinant Protein Products for PIGC: 
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    Cloud-Clone Corp. Proteins for PIGC 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000506glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex IDA10944123
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0016021integral to membrane IEA--

    PIGC for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PIG: Phosphatidylinositol glycan anchor biosynthesis

    1 InterPro protein domain:
     IPR009450 Plno_GlcNAc_GPI2

    Graphical View of Domain Structure for InterPro Entry Q92535

    ProtoNet protein and cluster: Q92535

    UniProtKB/Swiss-Prot: PIGC_HUMAN, Q92535
    Similarity: Belongs to the PIGC family


    PIGC for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PIGC_HUMAN, Q92535
    Function: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to
    phosphatidylinositol, the first step of GPI biosynthesis
    Catalytic activity: UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP +
    6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol

         Genatlas biochemistry entry for PIGC:
    glycosylphosphatidylinositol (GPI) anchor synthesis,class C

         Enzyme Number (IUBMB): EC 2.4.1.1981

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity TAS8806613
    GO:0017176phosphatidylinositol N-acetylglucosaminyltransferase activity IEA--
         
    PIGC for ontologies           About GeneDecksing


    Animal Models:
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate PIGC:
    hsa-miR-2115
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for PIGC About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Post-translational modification: synthesis of GPI-anchored proteins
    Post-translational modification: synthesis of GPI-anchored proteins0.79
    Synthesis of glycosylphosphatidylinositol (GPI)0.64
    Glycosylphosphatidylinositol(GPI)-anchor biosynthesis0.79
    2Asparagine N-linked glycosylation
    Post-translational protein modification0.44
    Metabolism of proteins0.35
    3Metabolism
    Metabolic pathways0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    4        Reactome Pathways for PIGC
        Metabolism of proteins
    Post-translational modification: synthesis of GPI-anchored proteins
    Post-translational protein modification
    Synthesis of glycosylphosphatidylinositol (GPI)


    2         Kegg Pathways  (Kegg details for PIGC):
        Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: PIGC_HUMAN, Q92535
    Pathway: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis


    PIGC for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PIGC

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/10 Interacting proteins for PIGC (Q925352, 3 ENSP000002583244) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ZHX1Q9UKY12, 3, ENSP000002978574MINT-65062 I2D: score=5 STRING: ENSP00000297857
    KLF10Q131182, 3, ENSP000002854074MINT-8259205 I2D: score=2 STRING: ENSP00000285407
    PIGQQ9BRB33, ENSP000000262184I2D: score=3 STRING: ENSP00000026218
    DPM2O947773, ENSP000003221814I2D: score=2 STRING: ENSP00000322181
    PIGAENSP000003698204STRING: ENSP00000369820
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006501C-terminal protein lipidation TAS--
    GO:0006506GPI anchor biosynthetic process TAS8806613
    GO:0016254preassembly of GPI anchor in ER membrane TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    PIGC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PIGC for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PIGC

    10/898 HMDB Compounds for PIGC (see all 898)    About this table
    CompoundSynonyms CAS #PubMed Ids
    3-Dehydrosphinganine1-Hydroxy-2-amino-3-oxo-octadecane (see all 9)16105-69-4--
    3-O-Sulfogalactosylceramide (d18:1/12:0)Sulfatide (d18:1/12:0) (see all 13)852100-88-0--
    3-O-Sulfogalactosylceramide (d18:1/14:0)Sulfatide (d18:1/14:0) (see all 13)----
    3-O-Sulfogalactosylceramide (d18:1/16:0)Sulfatide (d18:1/16:0) (see all 13)862509-48-6--
    3-O-Sulfogalactosylceramide (d18:1/18:0)Sulfatide (d18:1/18:0) (see all 13)244215-65-4--
    3-O-Sulfogalactosylceramide (d18:1/18:1(9Z))Sulfatide (d18:1/18:1(9Z)) (see all 13)----
    3-O-Sulfogalactosylceramide (d18:1/20:0)Sulfatide (d18:1/20:0) (see all 13)265096-81-9--
    3-O-Sulfogalactosylceramide (d18:1/22:0)Sulfatide (d18:1/22:0) (see all 13)265096-83-1--
    3-O-Sulfogalactosylceramide (d18:1/24:0)Sulfatide (d18:1/24:0) (see all 16)151122-71-3--
    3-O-Sulfogalactosylceramide (d18:1/24:1(15Z))Sulfatide (d18:1/24:1(15Z)) (see all 13)151057-28-2--

    3 Novoseek inferred chemical compound relationships for PIGC gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    udp-n-acetylglucosamine 78.6 1 8806613 (1)
    n-acetylglucosamine 76 1 8806613 (1)
    phosphatidylinositol 61.9 1 8806613 (1)

    Search CenterWatch for drugs/clinical trials and news about PIGC

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PIGC gene (2 alternative transcripts): 
    NM_002642.3  NM_153747.1  

    Unigene Cluster for PIGC:

    Phosphatidylinositol glycan anchor biosynthesis, class C
    Hs.188456  [show with all ESTs]
    Unigene Representative Sequence: NM_002642
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000489002 ENST00000465374 ENST00000475059 ENST00000484368(uc001gii.1)
    ENST00000488806 ENST00000344529 ENST00000367728(uc021pey.1) ENST00000478184
    ENST00000258324(uc001gin.3 uc001gio.3)
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    Additional mRNA sequence: 

    AK308201.1 BC006539.2 BT006734.1 CR450292.1 

    7 DOTS entries:

    DT.91759351  DT.444042  DT.121390224  DT.100770511  DT.91759361  DT.100832087  DT.106263 

    24/219 AceView cDNA sequences (see all 219):

    CR606378 CR619683 BX092985 CR606898 CB240824 CR602183 NM_002642 AV660576 
    AU104999 CR597603 CA413594 NM_153747 CR610325 AA505964 AL035301 AI125856 
    BC006539 AI657162 D58610 AU099284 BG198078 BT006734 AW026142 AI524548 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PIGC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGTAACATA
    PIGC Expression
    About this image


    See PIGC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PIGC

    SOURCE GeneReport for Unigene cluster: Hs.188456
        SABiosciences Custom PCR Arrays for PIGC
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIGC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PIGC gene from 9/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pigc1 , 5 phosphatidylinositol glycan anchor biosynthesis, class more1, 5 86.53(n)1
    93.6(a)1
      1 (69.95 cM)5
    672921  NM_001039045.11  NP_001034134.11 
     1619691865 
    chicken
    (Gallus gallus)
    Aves PIGC1 phosphatidylinositol glycan anchor biosynthesis, class more 74.2(n)
    82.98(a)
      424387  XM_422231.3  XP_422231.2 
    lizard
    (Anolis carolinensis)
    Reptilia PIGC6
    Uncharacterized protein
    78(a)
    1 ↔ 1
    GL343959.1(81027-81926)
    zebrafish
    (Danio rerio)
    Actinopterygii pigc1 phosphatidylinositol glycan, class C 59.43(n)
    55.16(a)
      323994  NM_213261.1  NP_998426.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG120771 CG12077 48.64(n)
    39.26(a)
      38410  NM_139547.2  NP_647804.2 
    worm
    (Caenorhabditis elegans)
    Secernentea T20D3.81 Protein T20D3.8 47.71(n)
    33.59(a)
      177765  NM_069244.1  NP_501645.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GPI21 Gpi2p 39.96(n)
    25.97(a)
      856029   NP_015249.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SETH11 phosphatidylinositol glycan, class C 46.35(n)
    35.77(a)
      818062  NM_129050.1  NP_181043.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g06222001 hypothetical protein 46.24(n)
    34.15(a)
      4330019  NM_001054001.1  NP_001047466.1 


    ENSEMBL Gene Tree for PIGC (if available)
    TreeFam Gene Tree for PIGC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PIGC gene

    PIGC for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for PIGC
    PGOHUM00000242204 PGOHUM00000233522


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1 SNPs in PIGC are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0113604
    ----see VAR_0113602 P S mis40--------

    HapMap Linkage Disequilibrium report for PIGC (172339329 - 172413230 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for PIGC: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing PIGC
    DNA2.0 Custom Variant and Variant Library Synthesis for PIGC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601730    OMIM disorders: --

    2 diseases for PIGC:    About MalaCards
    lassa fever    

    1 disease from the University of Copenhagen DISEASES database for PIGC:
    Lassa fever

    PIGC for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: PIGC (1 document)

    Export disorders for PIGC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PIGC gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with PIGC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2. (PubMed id 8806613)1, 2, 3, 9 Inoue N.... Kinoshita T. (1996)
    2. Structures and chromosomal localizations of the glycosylphosphatidylinositol synthesis gene PIGC and its pseudogene PIGCP1. (PubMed id 9325057)1, 2, 3, 9 Hong Y....Kinoshita T. (1997)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2. (PubMed id 10944123)1, 9 Watanabe R.... Kinoshita T. (2000)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distr ibution. (PubMed id 20935629)1 Heid I.M....Lindgren C.M. (2010)
    8. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
    9. Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins. (PubMed id 12655644)1 Eisenhaber B....Eisenhaber F. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5279 HGNC: 8960 AceView: PIGC Ensembl:ENSG00000135845 euGenes: HUgn5279
    ECgene: PIGC Kegg: 5279 H-InvDB: PIGC

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PIGC Pharmacogenomics, SNPs, Pathways
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_556

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PIGC gene:
    Search GeneIP for patents involving PIGC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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