PIGB Gene
protein-coding GIFtS: 57
GCID: GC15P055611
|
|
phosphatidylinositol glycan anchor biosynthesis, class B(Previous names: phosphatidylinositol glycan, class B )
| |
Aliases
for PIGB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Phosphatidylinositol Glycan Anchor Biosynthesis, Class B1 2 | | GPI Mannosyltransferase III2 3 | | Phosphatidylinositol Glycan, Class B1 2 | | GPI Mannosyltransferase 32 | | Phosphatidylinositol-Glycan Biosynthesis Class B Protein2 3 | | EC 2.4.1.-3 | | GPI-MT-III2 3 | | EC 2.4.18 | | PIG-B2 3 | | |
Export aliases for PIGB gene to outside databasesPrevious GC identifers: GC15P051169 GC15P048658 GC15P053190 GC15P053327 GC15P053398 GC15P032437 |
Summaries
for PIGB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PIGB:
This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchorbiosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves toanchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose(Dol-P-Man) dependent mannosyltransferases. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: PIGB_HUMAN, Q92521Function: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the thirdalpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly
Gene Wiki entry for PIGB
|
Genomic Views
for PIGB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PIGB gene promoter:
C/EBPbeta RelA STAT5A NRSF form 2 c-Rel Zic1 FOXO1a ZID FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PIGB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PIGB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q21.3 Ensembl cytogenetic band: 15q21.3 HGNC cytogenetic band: 15q21.3PIGB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P055611: view genomic region
(about GC identifiers)
Start:
|
55,611,133 bp from pter |
End:
|
55,647,846 bp from pter |
Size:
|
36,714 bases |
Orientation:
|
plus strand |
|
Proteins
for PIGB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PIGB_HUMAN, Q92521 (See
protein sequence)Recommended Name: GPI mannosyltransferase 3 Size: 554 amino acids; 65056 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Secondary accessions: Q53FF9 Q8WVN7Explore the universe of human proteins at neXtProt for PIGB: NX_Q92521
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q92521
4/7 DME Specific Peptides for PIGB (Q92521) (see all 7)
PIGB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004846.4
ENSEMBL proteins: ENSP00000455943 ENSP00000164305 ENSP00000456285 ENSP00000456531 ENSP00000455040 ENSP00000438963 Reactome Protein details: Q92521
Human Recombinant Protein Products for PIGB:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005789 | endoplasmic reticulum membrane |
TAS | -- | | GO:0016021 | integral to membrane |
NAS | 8861954 | | GO:0031227 | intrinsic to endoplasmic reticulum membrane |
IEA | -- |
PIGB for ontologies About GeneDecksing
PIGB Antibody Products:
Assay Products for PIGB: |
Protein
Domains /
Families
for PIGB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PIGB for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q92521ProtoNet protein and cluster: Q92521 1 Blocks protein family: IPB005599 Plasmid Maintenance Protein
UniProtKB/Swiss-Prot: PIGB_HUMAN, Q92521Similarity: Belongs to the glycosyltransferase 22 family. PIGB subfamily |
Function
for PIGB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: PIGB_HUMAN, Q92521Function: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the thirdalpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly Genatlas biochemistry entry for PIGB:glycosyl-phosphatidylinositol (GPI) anchor synthesis,class B
Enzyme Numbers (IUBMB): EC 2.4.12 EC 2.4.1.-1
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000030 | mannosyltransferase activity |
IDA | 8861954 | | GO:0016757 | transferase activity, transferring glycosyl groups |
-- | -- |
PIGB for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PIGB (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PIGB
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PIGB (NM_004855) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PIGB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIGB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIGB |
|
Pathways & Interactions
for PIGB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Post-translational modification: synthesis of GPI-anchored proteins | | | 2 | Asparagine N-linked glycosylation | | | 3 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4 
Reactome Pathways for PIGB
2 
Kegg Pathways (Kegg details for PIGB):
UniProtKB/Swiss-Prot: PIGB_HUMAN, Q92521Pathway: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis
PIGB for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PIGB
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/17 Interacting proteins for PIGB (Q925213 ENSP000001643054) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006501 | C-terminal protein lipidation |
TAS | -- | | GO:0006506 | GPI anchor biosynthetic process |
IDA | 8861954 | | GO:0016254 | preassembly of GPI anchor in ER membrane |
TAS | -- | | GO:0043687 | post-translational protein modification |
TAS | -- | | GO:0044267 | cellular protein metabolic process |
TAS | -- |
PIGB for ontologies About GeneDecksing
|
Drugs & Compounds
for PIGB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PIGB
10/898 HMDB Compounds for PIGB (see all 898) About this table
Search CenterWatch for drugs/clinical trials and news about PIGB
|
Transcripts
for PIGB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PIGB gene: NM_004855.4 Unigene Cluster for PIGB: Phosphatidylinositol glycan anchor biosynthesis, class B Hs.612814 [show with all ESTs]Unigene Representative Sequence: NM_00485512 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000565367 ENST00000164305(uc002act.3 uc010ugg.2) ENST00000569909
ENST00000570059 ENST00000566999 ENST00000566072 ENST00000565402 ENST00000565502
ENST00000563742 ENST00000569823 ENST00000562751 ENST00000539642
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PIGB (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PIGB
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PIGB (NM_004855) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PIGB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIGB |
Additional cDNA sequence: AK223330.1 AK293666.1 AK314706.1 BC017711.1 D42138.1 14 DOTS entries: DT.444271 DT.75103232 DT.95171373 DT.91737729 DT.95171371 DT.318391 DT.100787663 DT.318388 DT.121055554 DT.318389 DT.91722232 DT.91922208 DT.97789971 DT.95144894 24/68 AceView cDNA sequences (see all 68): BQ436473 BX432985 BP369083 BX282468 CR591869 BI222368 AF052498 AA644686 D42138 NM_004855 AA385310 BX447668 CA444909 AW175964 CB215160 BM966989 AA461248 N51160 BQ271124 BX505311 AI702363 N47966 BX493455 AI913301
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for PIGB (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PIGB
|
Expression
for PIGB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PIGB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAATACAAT
About this image
See PIGB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PIGB
SOURCE GeneReport for Unigene cluster: Hs.612814
SABiosciences Custom PCR Arrays for PIGB
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PIGB
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PIGB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PIGB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PIGB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIGB |
Orthologs
for PIGB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for PIGB gene from 10/33 species (see all 33) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Pigb1 , 5 |
phosphatidylinositol glycan anchor biosynthesis, class more1, 5 |
79.04(n)1
81.25(a)1 |
|
9 (40.08 cM)5
559811 NM_018889.31 NP_061377.21
730156965 |
chicken
(Gallus gallus) |
Aves |
PIGB1 |
phosphatidylinositol glycan anchor biosynthesis, class more |
70.35(n)
71.25(a) |
|
100858627 XM_003641880.1 XP_003641928.1 |
lizard
(Anolis carolinensis) |
Reptilia |
PIGB6 |
-- |
53(a) |
1 ↔ 1 |
AAWZ02037309(16069-17346) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.103582 |
Xenopus laevis transcribed sequence with weak similarity more |
77.58(n) |
|
CA973249.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc636582 |
hypothetical protein MGC63658 |
72.89(n) |
|
393448 BC055191.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG120061 , 3 |
CG120061 |
40(a)3
49.89(n)1
44.82(a)1 |
|
63F13
384461 NM_206269.21 NP_995991.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
T27F7.3a3 |
-- |
36(a) |
|
II(4991576-4993066) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
GPI10(YGL142C)4
GPI101 |
Integral membrane protein involved in glycosylphosphatidylinositol more4
Gpi10p1 |
46.23(n)1
34.4(a)1 |
|
7(238119-236269)4
8527351, 4 NP_011373.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G148501 |
phosphatidylinositol glycan, class B |
50.9(n)
42.5(a) |
|
831337 NM_121489.1 NP_568305.1 |
rice
(Oryza sativa) |
Liliopsida |
Os01g05801001 |
hypothetical protein |
50.28(n)
42.68(a) |
|
4324190 NM_001049939.1 NP_001043404.1 |
ENSEMBL Gene Tree for PIGB (if available)
TreeFam Gene Tree for PIGB (if available) |
Paralogs
for PIGB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for PIGB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PIGB (55611133 - 55647846 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PIGB: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PIGB |
|
Disorders
/ Diseases
for PIGB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PIGB for disorders About GeneDecksing
OMIM gene information: 604122
OMIM disorders: --
4  diseases for PIGB: About MalaCardssleeping sickness encephalomalacia griscelli syndrome malaria
Human Genome Epidemiology (HuGE) Navigator: PIGB (1 document)
Export disorders for PIGB gene to outside databases
|
Publications
for PIGB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PIGB gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with PIGB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor. (PubMed id 8861954)1, 2, 3, 9 Takahashi M.... Kinoshita T. (1996)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Glycoinositol phospholipid anchor-defective K562 mutants with biochemical lesions distinct from those in Thy-1- murine lymphoma mutants. (PubMed id 7907094)1, 2 Mohney R.P.... Medof M.E. (1994)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells. (PubMed id 18198489)1 Hwang G.W....Naganuma A. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Evidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5A. (PubMed id 12058346)1 Anikster Y.... Hurvitz H. (2002)
- Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis. (PubMed id 11102867)1 Kinoshita T. and Inoue N. (2000)
|
External Searches for PIGB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PIGB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PIGB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PIGB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PIGB | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PIGB gene:
Search GeneIP for patents involving PIGB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PIGB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PIGB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PIGB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PIGB | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PIGB | | OriGene 3'-UTR Clone for PIGB | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PIGB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PIGB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PIGB | | OriGene Custom Protein Services for PIGB | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PIGB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PIGB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PIGB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PIGB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PIGB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PIGB |
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| | | | Search Tocris compounds for PIGB |
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 | | | PIGB Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIGB |
|  |  |  |  | | | | Search ThermoFisher Antibodies for PIGB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PIGB |
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