Aliases for PIGB Gene
External Ids for PIGB Gene
Previous GeneCards Identifiers for PIGB Gene
This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases. [provided by RefSeq, Jul 2008]
GeneCards Summary for PIGB Gene
PIGB (Phosphatidylinositol Glycan Anchor Biosynthesis Class B) is a Protein Coding gene. Diseases associated with PIGB include griscelli syndrome. Among its related pathways are Metabolism and Transport to the Golgi and subsequent modification. GO annotations related to this gene include transferase activity, transferring glycosyl groups and mannosyltransferase activity.
UniProtKB/Swiss-Prot for PIGB Gene
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.