Aliases for PIGB Gene
External Ids for PIGB Gene
Previous GeneCards Identifiers for PIGB Gene
This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases. [provided by RefSeq, Jul 2008]
GeneCards Summary for PIGB Gene
PIGB (Phosphatidylinositol Glycan Anchor Biosynthesis Class B) is a Protein Coding gene. Among its related pathways are Glycosylphosphatidylinositol (GPI)-anchor biosynthesis and Post-translational modification- synthesis of GPI-anchored proteins. GO annotations related to this gene include transferase activity, transferring glycosyl groups and mannosyltransferase activity.
UniProtKB/Swiss-Prot for PIGB Gene
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.