PIAS3 Gene
protein-coding GIFtS : 62 GCID: GC01 P145575
Protein Inhibitor Of Activated STAT, 3
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Aliasesfor PIAS3 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section Aliases Protein Inhibitor Of Activated STAT, 3 1 2 ZMIZ52 Protein Inhibitor Of Activated STAT Protein 32 3 E3 SUMO-Protein Ligase PIAS32 MIZ-Type Containing 51 Zinc Finger, MIZ-Type Containing 52 Zinc Finger1 EC 6.3.2.-3
Export aliases for PIAS3 gene to outside databases Previous GC identifers: GC01P144096 GC01P142163 GC01P143302 GC01P143324 GC01P143065 GC01P144287 GC01P119540
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Summariesfor PIAS3 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for PIAS3 Gene: This gene encodes a member of the PIAS (protein inhibitor of activated STAT (signal transducer and activator of transcription)) family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. (provided by RefSeq, Jul 2008) GeneCards Summary for PIAS3 Gene: PIAS3 (protein inhibitor of activated STAT, 3) is a protein-coding gene. Diseases associated with PIAS3 include alcoholic hepatitis microphthalmia related super-pathways are Development Thrombopoetin signaling via JAK-STAT pathway and PEDF Induced Signaling . GO annotations related to this gene include protein C-terminus binding and nucleic acid binding . An important paralog of this gene is ZMIZ2 . UniProtKB/Swiss-Prot: PIAS3_HUMAN, Q9Y6X2 Function : Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction betweenUBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth Gene Wiki entry for PIAS3 Gene
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Genomic Viewsfor PIAS3 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 73) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NT_167185.1 NC_018912.2 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the PIAS3 gene promoter:TBP MAZR HTF E47 GATA-1 GATA-2 YY1 TFIID Other transcription factors Search SABiosciences Chromatin IP Primers for PIAS3 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1q21 Ensembl cytogenetic band: 1q21.1 HGNC cytogenetic band: 1q21 PIAS3 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01P145575: view genomic region
(about GC identifiers )
Start: 145,575,233 bp from pter End:
145,586,546 bp from pter
Size: 11,314 bases Orientation:
plus strand
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Proteinsfor PIAS3 gene
(According to
UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MAXQB
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section UniProtKB/Swiss-Prot: PIAS3_HUMAN, Q9Y6X2 See
protein sequence )Recommended Name: Size : 628 amino acids; 68017 DaSubunit : Monomer (By similarity). Binds SUMO1 and UBE2I. Interacts with BCL11A, HMGA2, IRF1, MITF and NCOA2. Interactswith STAT5; the interaction occurs on stimulation by PRL. Interacts with GFI1; the interaction relieves the inhibitory effect of PIAS3 on STAT3-mediated transcriptional activity (By similarity). Interacts with AR, PLAG1 and ZFHX3. Interacts with STAT3; the interaction occurs on stimulation by IL6, CNTF or OSM and inhibits the DNA binding activity of STAT3
Subcellular location : Cytoplasm. Nucleus. Note=Mainly cytoplasmic but shuttles between the nucleus and cytoplasm.Transported to the nucleus on interaction with phosphorylated STAT3. Colocalizes with GFI1 in nuclear dots (By similarity)
Sequence caution : Sequence=BAA78533.1; Type=Erroneous initiation;Secondary accessions : Q9UFI3Explore the universe of human proteins at neXtProt for PIAS3: NX_Q9Y6X2 Explore proteomics data for PIAS3 at MOPED Post-translational modifications:
UniProtKB: Sumoylated (By similarity) View modification sites using PhosphoSitePlus View neXtProt modification sites for NX_Q9Y6X2 PIAS3 Protein expression data from MOPED1 2 3 : About this image REFSEQ proteins: NP_006090.2 ENSEMBL proteins: ENSP00000376766 ENSP00000476245 ENSP00000376765 ENSP00000358304 ENSP00000358305 Human Recombinant Protein Products for PIAS3: Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing PIAS3 Antibody Products: Assay Products for PIAS3:
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Protein
Domains /for PIAS3 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section HGNC Gene Families: ZMIZ: Zinc fingers, MIZ-type 4 InterPro protein domains :
Graphical View of Domain Structure for InterPro Entry Q9Y6X2 ProtoNet protein and cluster: Q9Y6X2
2 Blocks protein domains : IPB003034 IPB004181 UniProtKB/Swiss-Prot: PIAS3_HUMAN, Q9Y6X2 Domain : The PINIT domain of PIAS3 is required for STAT3-PIAS3 interaction and for transloaction to the nucleusDomain : The LXXLL motif is a transcriptional coregulator signatureSimilarity : Belongs to the PIAS familySimilarity : Contains 1 PINIT domainSimilarity : Contains 1 SAP domainSimilarity : Contains 1 SP-RING-type zinc fingerAbout GeneDecksing
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Functionfor PIAS3 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: PIAS3_HUMAN, Q9Y6X2 Function : Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction betweenUBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth Induction : By dihydrotestosterone (DHT) in prostate cancer cells Enzyme Number (IUBMB): EC 6.3.2.- 1
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8 ): About this table
About GeneDecksing Animal Models: In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIAS3
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Pathways & Interactionsfor PIAS3 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene) .
About This Section SuperPaths for PIAS3 About (see all 15 ) See pathways by source SuperPath Contained pathways About 1 Development Thrombopoetin signaling via JAK-STAT pathway 2 PEDF Induced Signaling 3 TGF-Beta Pathway 4 Development Leptin signaling via JAK/STAT and MAPK cascades 5 Development Prolactin receptor signaling
Pathways by source See SuperPaths Show all pathways 2 2 1 2 5/9 (see all 9 )2 (Kegg details for PIAS3) :UniProtKB/Swiss-Prot: PIAS3_HUMAN, Q9Y6X2 Pathway : Protein modification; protein sumoylationAbout GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PIAS3 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/82 Interacting proteins for PIAS3 (Q9Y6X2 2 , 3 ENSP00000376765 4 via UniProtKB, MINT, STRING , and/or I2D (see all 82 )
About this table Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7 ): About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006351 transcription, DNA-dependent
IEA -- GO:0006355 regulation of transcription, DNA-dependent
IEA -- GO:0009725 response to hormone stimulus
IEA -- GO:0010628 positive regulation of gene expression
IEA -- GO:0016925 protein sumoylation
ISS --
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Drugs & Compoundsfor PIAS3 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
IUPHAR ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for PIAS3 PIAS3
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Transcriptsfor PIAS3 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for PIAS3 gene: NM_006099.3 Unigene Cluster for PIAS3:
Protein inhibitor of activated STAT, 3 Hs.435761 [show with all ESTs ] Unigene Representative Sequence: BC030556 9 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000393046 ENST00000463514 ENST00000393045 (uc001eoc.1 ) ENST00000369298 ENST00000484423 ENST00000498436 ENST00000475261 (uc001eod.1 ) ENST00000472114 ENST00000369299 (uc010oyy.1 ) Primer PIAS3 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat
Additional mRNA sequence: AB021868.1 AK027557.1 AK294231.1 AK304039.1 AL122061.1 BC001154.1 BC030556.1 BT007036.1 CR457090.1
12 DOTS entries : DT.444950 DT.95297810
DT.95073200 DT.95072139 DT.86857437 DT.121360682 DT.95073199 DT.95239075 DT.121360641 DT.121360655 DT.95073202 DT.99941193 24/208 AceView cDNA sequences (see all 208 ):
AU118455 AU279846 CB156534 BQ436701 AL582931 CA396111 AA375243 BM701760 BP377967 BI823858 CA489770 BM715935 BQ921259 BU508963 BM452958 BQ921265 BU178124 BU183507 BP366023 BP365437 CB158728 AW297008 NM_006099 CR590421 GeneLoc Exon Structure 5/13 Alternative Splicing Database (ASD) splice patterns (SP) for PIAS3 (see all 13 ) About this scheme ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b · 13c ^ 14 ^ SP1 : - - - - - SP2 : - - - SP3 : - SP4 : - - - - - - - - SP5 : - - - - - -
ExUns: 15a · 15b ^ 16a · 16b · 16c ^ 17a · 17b SP1 : - - - SP2 : SP3 : - - - SP4 : SP5 :
ECgene alternative splicing isoforms for PIAS3
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Expression for PIAS3 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section PIAS3 expression in normal human tissues
(normalized intensities) PIAS3 embryonic expression: see See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: GCCCTGTAGTAbout this image
PIAS3 expression in embryonic tissues and stem cells About this table LifeMap ,
the Embryonic Development and Stem Cells Database 5/5 selected tissues (see all 5 ) fully expand See PIAS3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for PIAS3 SOURCE GeneReport for Unigene cluster: Hs.435761 UniProtKB/Swiss-Prot: PIAS3_HUMAN, Q9Y6X2 Tissue specificity : Isoform 1 is expressed in most tissues except thymus and small intestine. Isoform 3 is expressedonly in brain, heart, thymus, muscle, lung, testis, lactating breast and embryonic stem cells SABiosciences Custom PCR Arrays for PIAS3 Primer PIAS3 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIAS3
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Orthologsfor PIAS3 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for PIAS3 gene from 6/14 species (see all 14 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia Pias31 5
protein inhibitor of activated STAT 31, 5
90.39(n) 1 96.97(a) 1
3 (41.95 cM) 5 229615 1 NM_001165949.1 1 NP_001159421.1 1 96696384 5
chicken Aves PIAS36
protein inhibitor of activated STAT, 3
60(a)
1 ↔ 1
25(645944-647516)
lizard Reptilia PIAS36
Uncharacterized protein
65(a)
1 ↔ 1
AAWZ02037198(80-14535)
fruit fly Insecta Su(var)2-103
chromosome condensation DNA binding
44(a)
2 45A8 --
worm Secernentea gei-173
--
36(a)
I(9109589-9115598) --
baker's yeast Saccharomycetes NFI16 6
SUMO E3 ligase, catalyzes the covalent attachment ... SUMO/Smt3 ligase that promotes the attachment of s... 11(a) 10(a)
many ↔ manymany ↔ many
XV(628360-630540) IV(1289406-1292120)
ENSEMBL Gene Tree for PIAS3 (if available)TreeFam Gene Tree for PIAS3 (if available)
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Paralogsfor PIAS3 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for PIAS3 gene ZMIZ2 2 PIAS1 2 PIAS2 2 ZMIZ1 2 PIAS4 2 5 SIMAP similar genes for PIAS3 using alignment to 5 protein entries: PIAS3_HUMAN (see all proteins ):DKFZp727A051 PIAS1 PIAS2 DKFZp434O0617 PIAS4 About GeneDecksing
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Genomic Variantsfor PIAS3 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 1 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for PIAS3 (145575233 - 145586546 bp)
Structural Variations Database of Genomic Variants (DGV) 8 variations for PIAS3 : About this table SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor PIAS3 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Novoseek , Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 605987
OMIM disorders : --12 : About MalaCards alcoholic hepatitis microphthalmia multiple myeloma alcoholism hepatitis c myeloma prostatitis hepatitis prostate cancer lung cancer endotheliitis breast cancer 1 disease from the University of Copenhagen DISEASES database for PIAS3 :Microphthalmia 1 Novoseek inferred disease relationship for PIAS3 gene About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
prostate cancer
11.9
2
15138572 (1), 11071847 (1)
Export disorders for PIAS3 gene to outside databases
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Publicationsfor PIAS3 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for PIAS3 gene, integrated from 9 sources (see all 78 ):(articles sorted by number of sources associating them with PIAS3) Utopia : connect your pdf to the dynamic
Isolation and chromosomal assignment of a human gene encoding protein inhibitor of activated STAT3 (PIAS3). (PubMed id 10319586) 1 , 2 , 3(1999) Specific inhibition of Stat3 signal transduction by PIAS3. (PubMed id 9388184) 1 , 2 , 9(1997) Protein inhibitor of activated STAT3 regulates androgen receptor signaling in prostate carcinoma cells. (PubMed id 11071847) 1 , 2 , 9(2000) ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3. (PubMed id 14715251) 1 , 2 (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3. (PubMed id 11060035) 1 , 2 (2000) Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3). (PubMed id 14691252) 1 , 9(2004) The association and nuclear translocation of the PIAS 3-STAT3 complex is ligand and time dependent. (PubMed id 19903771) 1 , 9(2009) Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3. (PubMed id 16368885) 1 , 9(2006) Differential PIAS3 expression in human malignancy. (PubMed id 15138572) 1 , 9(2004)
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External Searches for PIAS3 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing PIAS3 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing PIAS3 gene
(According to HUGE )
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Specialized Databases showing PIAS3 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for PIAS3 gene: PIAS3 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor PIAS3 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PIAS3 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Antibodies & Assays for PIAS3
Search Tocris compounds for PIAS3
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PIAS3
ThermoFisher Antibodies for PIAS3
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat PIAS3
LSBio Antibodies in human mouse rat
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GeneGo (Thomson Reuters) Pathways for PIAS3
Kegg Pathways 
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