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Aliases for PI4KAP2 Gene

Aliases for PI4KAP2 Gene

  • Phosphatidylinositol 4-Kinase Alpha Pseudogene 2 2 3 5
  • Phosphatidylinositol 4-Kinase, Catalytic, Alpha Pseudogene 2 2
  • EC 2.7.1.67 61

External Ids for PI4KAP2 Gene

Previous GeneCards Identifiers for PI4KAP2 Gene

  • GC22M020158
  • GC22M021828
  • GC22M004865

Summaries for PI4KAP2 Gene

GeneCards Summary for PI4KAP2 Gene

PI4KAP2 (Phosphatidylinositol 4-Kinase Alpha Pseudogene 2) is a Pseudogene. GO annotations related to this gene include kinase activity and phosphotransferase activity, alcohol group as acceptor.

Gene Wiki entry for PI4KAP2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PI4KAP2 Gene

Genomics for PI4KAP2 Gene

Regulatory Elements for PI4KAP2 Gene

Enhancers for PI4KAP2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G021834 1.4 Ensembl ENCODE dbSUPER 5 -319.1 -319086 4.4 PKNOX1 FOXA2 PTBP1 ATF1 INSM2 ZNF366 SCRT2 KLF13 EGR2 ZNF362 ENSG00000224086 TOP3BP1 PPM1F PI4KAP2 MAPK1 RNA5SP493
GH22G021457 1 ENCODE 6.3 +60.1 60105 0.8 PKNOX1 FOXA2 ARID4B DMAP1 ZNF48 YY1 SLC30A9 FOS ZNF202 ZHX2 ABHD17AP4 PI4KAP2 GC22M021449 ENSG00000276800
GH22G021510 0.8 Ensembl 0.4 +6.7 6733 0.4 FEZF1 GATA3 ZFHX2 GATA2 ZNF366 SCRT2 ZSCAN5C KLF7 PRDM10 EGR2 PI4KAP2 GC22P021943
GH22G021531 0.7 Ensembl 0.4 -14.4 -14379 1.3 HDGF BCOR SMARCA5 YBX3 CBX3 ZBTB2 YBX1 KAT8 MCM7 NCOR1 GC22P021917 PI4KAP2
GH22G021496 0.7 Ensembl 0.4 +18.8 18833 3.8 FOXA2 ZNF621 GTF2E2 ZNF384 FOXA1 OSR2 POLR2H PRDM6 ZNF157 GLIS1 ENSG00000273342 ENSG00000274422 TUBA3FP PI4KAP2 GC22P021943
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PI4KAP2 on UCSC Golden Path with GeneCards custom track

Promoters for PI4KAP2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000144022 233 1801

Genomic Location for PI4KAP2 Gene

Chromosome:
22
Start:
21,472,998 bp from pter
End:
21,517,533 bp from pter
Size:
44,536 bases
Orientation:
Minus strand

Genomic View for PI4KAP2 Gene

Genes around PI4KAP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PI4KAP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PI4KAP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PI4KAP2 Gene

Proteins for PI4KAP2 Gene

  • Protein details for PI4KAP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A4QPH2-PI4P2_HUMAN
    Recommended name:
    Putative phosphatidylinositol 4-kinase alpha-like protein P2
    Protein Accession:
    A4QPH2
    Secondary Accessions:
    • Q6ICJ0
    • Q6ZT68
    • Q8WUK7

    Protein attributes for PI4KAP2 Gene

    Size:
    592 amino acids
    Molecular mass:
    66944 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI39842.2; Type=Miscellaneous discrepancy; Note=Contaminating sequence.; Evidence={ECO:0000305};

    Alternative splice isoforms for PI4KAP2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PI4KAP2 Gene

Selected DME Specific Peptides for PI4KAP2 Gene

A4QPH2:
  • GHIIHIDFGF
  • KDRHNGN

Post-translational modifications for PI4KAP2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Domains & Families for PI4KAP2 Gene

Protein Domains for PI4KAP2 Gene

Suggested Antigen Peptide Sequences for PI4KAP2 Gene

Graphical View of Domain Structure for InterPro Entry

A4QPH2

UniProtKB/Swiss-Prot:

PI4P2_HUMAN :
  • Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
Family:
  • Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
genes like me logo Genes that share domains with PI4KAP2: view

No data available for Gene Families for PI4KAP2 Gene

Function for PI4KAP2 Gene

Enzyme Numbers (IUBMB) for PI4KAP2 Gene

Gene Ontology (GO) - Molecular Function for PI4KAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004430 1-phosphatidylinositol 4-kinase activity IBA --
genes like me logo Genes that share ontologies with PI4KAP2: view
genes like me logo Genes that share phenotypes with PI4KAP2: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PI4KAP2 Gene

Localization for PI4KAP2 Gene

Gene Ontology (GO) - Cellular Components for PI4KAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005886 plasma membrane IBA --
genes like me logo Genes that share ontologies with PI4KAP2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for PI4KAP2 Gene

Pathways & Interactions for PI4KAP2 Gene

SuperPathways for PI4KAP2 Gene

No Data Available

Interacting Proteins for PI4KAP2 Gene

Selected Interacting proteins: A4QPH2-PI4P2_HUMAN for PI4KAP2 Gene via IID

Symbol External ID(s) Details
APPBP2

Gene Ontology (GO) - Biological Process for PI4KAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046854 phosphatidylinositol phosphorylation IEA --
GO:0048015 phosphatidylinositol-mediated signaling IEA --
genes like me logo Genes that share ontologies with PI4KAP2: view

No data available for Pathways by source and SIGNOR curated interactions for PI4KAP2 Gene

Drugs & Compounds for PI4KAP2 Gene

No Compound Related Data Available

Transcripts for PI4KAP2 Gene

Unigene Clusters for PI4KAP2 Gene

Phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PI4KAP2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9
SP1: -
SP2:
SP3:

Relevant External Links for PI4KAP2 Gene

GeneLoc Exon Structure for
PI4KAP2
ECgene alternative splicing isoforms for
PI4KAP2

Expression for PI4KAP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PI4KAP2 Gene

Protein differential expression in normal tissues from HIPED for PI4KAP2 Gene

This gene is overexpressed in Heart (43.4) and Brain (25.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PI4KAP2 Gene



Protein tissue co-expression partners for PI4KAP2 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PI4KAP2 Gene:

PI4KAP2

SOURCE GeneReport for Unigene cluster for PI4KAP2 Gene:

Hs.448225
genes like me logo Genes that share expression patterns with PI4KAP2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PI4KAP2 Gene

Orthologs for PI4KAP2 Gene

Evolution for PI4KAP2 Gene

ENSEMBL:
Gene Tree for PI4KAP2 (if available)
TreeFam:
Gene Tree for PI4KAP2 (if available)

No data available for Orthologs for PI4KAP2 Gene

Paralogs for PI4KAP2 Gene

(4) SIMAP similar genes for PI4KAP2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PI4KAP2: view

No data available for Paralogs for PI4KAP2 Gene

Variants for PI4KAP2 Gene

Sequence variations from dbSNP and Humsavar for PI4KAP2 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1000053309 -- 21,508,611(+) ATCAT(C/T)TGAGC intron-variant
rs1000271661 -- 21,511,222(+) GACTC(C/T)AACTT intron-variant
rs1000323872 -- 21,476,937(+) GGCTG(C/T)CTGGA intron-variant
rs1000436034 -- 21,485,886(+) CCACT(A/G)CACTC intron-variant
rs1000548320 -- 21,487,094(+) AGGTG(C/T)GGTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PI4KAP2 Gene

Variant ID Type Subtype PubMed ID
dgv4486n100 CNV gain 25217958
dgv4487n100 CNV gain 25217958
dgv4488n100 CNV gain 25217958
dgv4489n100 CNV gain 25217958
dgv4490n100 CNV gain 25217958
dgv4491n100 CNV gain 25217958
dgv820e199 CNV deletion 23128226
esv25508 CNV gain+loss 19812545
esv2678291 CNV deletion 23128226
esv2760719 CNV gain 21179565
esv2763699 CNV gain+loss 21179565
esv3584494 CNV gain 24956385
esv3893444 CNV gain 25118596
nsv1066391 CNV gain 25217958
nsv1072202 CNV deletion 25765185
nsv1073155 CNV deletion 25765185
nsv1118947 CNV deletion 24896259
nsv1126624 CNV deletion 24896259
nsv1126625 CNV deletion 24896259
nsv1133538 CNV deletion 24896259
nsv1144967 CNV deletion 24896259
nsv1160729 CNV duplication 26073780
nsv1160730 CNV deletion 26073780
nsv192 OTHER inversion 15895083
nsv428386 CNV loss 18775914
nsv436864 CNV insertion 17901297
nsv442791 CNV gain 18776908
nsv469545 CNV gain 16826518
nsv471596 CNV gain+loss 15918152
nsv511071 OTHER inversion 20534489
nsv7350 OTHER inversion 18451855
nsv834145 CNV loss 17160897
nsv953042 CNV deletion 24416366
nsv966081 CNV duplication 23825009

Relevant External Links for PI4KAP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PI4KAP2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PI4KAP2 Gene

Disorders for PI4KAP2 Gene

Relevant External Links for PI4KAP2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PI4KAP2

No disorders were found for PI4KAP2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PI4KAP2 Gene

Publications for PI4KAP2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for PI4KAP2 Gene

Sources for PI4KAP2 Gene

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