PHOX2A Gene
protein-coding GIFtS: 56
GCID: GC11M071950
|
|
paired-like homeobox 2a(Previous names: aristaless (Drosophila) homeobox, aristaless homeobox (Drosophila),...)
(Previous symbols: ARIX, FEOM2)
| |
Aliases
for PHOX2A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Paired-Like Homeobox 2a1 2 3 | | Aristaless (Drosophila) Homeobox, Aristaless Homeobox (Drosophila), Fibrosis OfExtraocular Muscles, Congenital, 2, Autosomal Recessive1 | | ARIX1 2 3 5 | | Paired-Like (Aristaless) Homeobox 2a1 | | PMX2A1 2 3 | | NCAM22 | | CFEOM21 2 5 | | Aristaless Homeobox Homolog2 | | FEOM21 2 | | Arix Homeodomain Protein2 | | Aristaless Homeobox Protein Homolog2 3 | | Paired Mesoderm Homeobox Protein 2A2 | | ARIX1 Homeodomain Protein2 3 | | |
Export aliases for PHOX2A gene to outside databasesPrevious GC identifers: GC11M073490 GC11M072172 GC11M071676 GC11M071627 GC11M068243 |
Summaries
for PHOX2A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PHOX2A:
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristalessgene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulatesthe expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymesessential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded proteinhas also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in thisgene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. (provided byRefSeq, Jul 2008)
UniProtKB/Swiss-Prot: PHX2A_HUMAN, O14813Function: May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts asa transcription activator/factor. Could maintain the noradrenergic phenotype
Gene Wiki entry for PHOX2A
|
Genomic Views
for PHOX2A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PHOX2A gene promoter:
GATA-3 Pax-5 AP-2alpha isoform 3 Nkx2-5 AP-2alpha isoform 2 GATA-2 GATA-1 AP-2alpha isoform 4 AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for PHOX2A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHOX2A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.2 Ensembl cytogenetic band: 11q13.4 HGNC cytogenetic band: 11q13.4PHOX2A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M071950: view genomic region
(about GC identifiers)
Start:
|
71,950,121 bp from pter |
End:
|
71,956,708 bp from pter |
Size:
|
6,588 bases |
Orientation:
|
minus strand |
|
Proteins
for PHOX2A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PHX2A_HUMAN, O14813 (See
protein sequence)Recommended Name: Paired mesoderm homeobox protein 2A Size: 284 amino acids; 29653 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: A8K3N0 Q8IVZ2Explore the universe of human proteins at neXtProt for PHOX2A: NX_O14813
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O14813
PHOX2A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005160.2
ENSEMBL proteins: ENSP00000444845 ENSP00000298231
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
PHOX2A for ontologies About GeneDecksing
PHOX2A Antibody Products:
Assay Products for PHOX2A: |
Protein
Domains /
Families
for PHOX2A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PHOX2A for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O14813ProtoNet protein and cluster: O14813 1 Blocks protein family: IPB000047 Lambda and other repressor helix-turn-helix signature
UniProtKB/Swiss-Prot: PHX2A_HUMAN, O14813Similarity: Belongs to the paired homeobox familySimilarity: Contains 1 homeobox DNA-binding domain |
Function
for PHOX2A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PHX2A_HUMAN, O14813Function: May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts asa transcription activator/factor. Could maintain the noradrenergic phenotype
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHOX2A (see first 1)
NM_005169 (human cat#: RC208331) NM_008887 (mouse cat#: MR226293) NM_053869 (rat cat#: RR203444)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHOX2A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PHOX2A (NM_005169) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PHOX2A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHOX2A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHOX2A |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
IDA | 16280598 | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- |
PHOX2A for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for PHOX2A: Phox2atm1Jbr Phox2a/Inppl1Phox2a/tm1Ssch
8 MGI mutant phenotypes (inferred from 6 alleles ) (MGI details for Phox2a):
PHOX2A for phenotypes About GeneDecksing
|
Pathways & Interactions
for PHOX2A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | SIDS Susceptibility Pathways | |
1  BioSystems Pathway for PHOX2A
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PHOX2A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/7 Interacting proteins for PHOX2A (O148133 ENSP000002982314) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003357 | noradrenergic neuron differentiation |
NAS | 16280598 | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
-- | -- | | GO:0021523 | somatic motor neuron differentiation |
IEA | -- | | GO:0021623 | oculomotor nerve formation |
IEA | -- |
PHOX2A for ontologies About GeneDecksing
|
Drugs & Compounds
for PHOX2A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PHOX2A for compounds About GeneDecksing
 Browse Tocris compounds for PHOX2A
3 Novoseek chemical compound relationships for PHOX2A gene About this table
Search CenterWatch for drugs/clinical trials and news about PHOX2A / PHX2A
|
Transcripts
for PHOX2A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PHOX2A gene: NM_005169.3 Unigene Cluster for PHOX2A: Paired-like homeobox 2a Hs.731565 [show with all ESTs]Unigene Representative Sequence: NM_0051693 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000546310 ENST00000298231(uc001osh.4) ENST00000544057
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHOX2A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHOX2A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PHOX2A (NM_005169) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PHOX2A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHOX2A |
Additional cDNA sequence: AK290645.1 BC041564.1 8 DOTS entries: DT.91698778 DT.120744895 DT.446512 DT.100792229 DT.100832859 DT.91760053 DT.91760060 DT.95190629 24/28 AceView cDNA sequences (see all 28): CR607262 CR593042 CR621077 BC041564 CR600761 CR596068 NM_005169 BU151137 CR607218 CR604478 CR590341 BQ899131 BI196975 AL522064 BQ881657 BX375756 BX376662 BE383103 AL529571 BQ890461 BQ070957 BF311651 BE383114 BE313749
GeneLoc Exon Structure
|
Expression
for PHOX2A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PHOX2A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGCCTGTCC
About this image
See PHOX2A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PHOX2A
SOURCE GeneReport for Unigene cluster: Hs.731565
SABiosciences Custom PCR Arrays for PHOX2A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PHOX2A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PHOX2A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHOX2A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHOX2A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHOX2A |
Orthologs
for PHOX2A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PHOX2A gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
F1NMR7_CHICK6 |
Uncharacterized protein |
54(a) |
possible ortholog |
4(70341621-70359039) |
lizard
(Anolis carolinensis) |
Reptilia |
PHOX2B6 |
-- |
83(a) |
possible ortholog |
5(100920164-100920370) |
zebrafish
(Danio rerio) |
Actinopterygii |
phox2a1 |
paired-like homeobox 2a |
69.55(n)
67.87(a) |
|
404602 NM_207070.1 NP_996953.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
PHDP6 |
Putative homeodomain protein |
27(a) |
1 → many |
2R(19770708-19771835) |
worm
(Caenorhabditis elegans) |
Secernentea |
ceh-176alr-16 |
Homeobox family member (ceh-17)AristaLess (Drosophila homeodomain) Related family... |
26(a)17(a) |
1 ↔ manypossible ortholog |
I(4568963-4570028) X(11122531-11125549) |
ENSEMBL Gene Tree for PHOX2A (if available)
TreeFam Gene Tree for PHOX2A (if available) |
Paralogs
for PHOX2A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PHOX2A gene
- ALX12 PITX12 PHOX2B2 RAX2 ARX2 VSX12 PRRX12 DRGX2
- PITX22 VSX22 ISX2 ALX42 RAX22 PITX32 ALX32 PRRX22
6 SIMAP similar genes for PHOX2A using alignment to 3 protein entries: PHX2A_HUMAN (see all proteins):PRRX1 PHOX2B PRRX2 DRGX ARX OTP
PHOX2A for paralogs About GeneDecksing
|
Genomic Variants
for PHOX2A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PHOX2A (71950121 - 71956708 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for PHOX2A
1 CNV: 71352
Human Gene Mutation Database (HGMD): PHOX2A
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PHOX2A |
|
Disorders
/ Diseases
for PHOX2A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PHOX2A for disorders About GeneDecksing
OMIM gene information: 602753
OMIM disorders: 602078
UniProtKB/Swiss-Prot: PHX2A_HUMAN, O14813
Defects in PHOX2A are the cause of congenital fibrosis of extraocular muscles type 2 (CFEOM2) [MIM:602078].CFEOM encompasses several different inherited strabismus syndromes characterized by congenital restrictiveophthalmoplegia affecting extraocular muscles innervated by the oculomotor and/or trochlear nerves. CFEOM ischaracterized clinically by anchoring of the eyes in downward gaze, ptosis, and backward tilt of the head. CFEOM2 mayresult from the aberrant development of the oculomotor (nIII), trochlear (nIV) and abducens (nVI) cranial nerve nuclei
18  diseases for PHOX2A: About MalaCardsfibrosis of extraocular muscles congenital fibrosis of the extraocular muscles fibrosis x-linked mental retardation with epilepsy
central hypoventilation syndrome paralytic squint sudden infant death syndrome congenital central hypoventilation syndrome
mental retardation epilepsy hypotropia brown syndrome exotropia
amblyopia strabismus ptosis hypertension
neuroblastoma neuronitis
4 diseases from the University of Copenhagen DISEASES database for PHOX2A:Exotropia Ophthalmoplegia Hypotropia Paralytic squint 3 Novoseek disease relationships for PHOX2A gene About this table
GeneTests: PHOX2A
Congenital Fibrosis of the Extraocular Muscles
Genetic Association Database (GAD): PHOX2A
Human Genome Epidemiology (HuGE) Navigator: PHOX2A (1 document)
Export disorders for PHOX2A gene to outside databases
|
Publications
for PHOX2A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PHOX2A gene, integrated from 9 sources (see all 61):
(articles sorted by number of sources associating them with PHOX2A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Homozygous mutations in ARIX(PHOX2A) result in congenital fibrosis of the extraocular muscles type 2. (PubMed id 11600883)1, 2, 3 Nakano M.... Engle E.C. (2001)
- Mapping of the ARIX homeodomain gene to mouse chromosome 7 and human chromosome 11q13. (PubMed id 8661014)1, 2, 3 Johnson K.R.... Lewis E.J. (1996)
- A novel PHOX2A/ARIX mutation in an Iranian family with congenital fibrosis of extraocular muscles type 2 (CFEOM2). (PubMed id 14597037)1, 4, 9 Yazdani A....Traboulsi E.I. (2003)
- Molecular analysis of congenital central hypoventilation syndrome. (PubMed id 14566559)1, 2, 9 Sasaki A.... Hayasaka K. (2003)
- Sudden infant death syndrome: case-control frequency differences at genes pertinent to early autonomic nervous system embryologic development. (PubMed id 15240857)1, 4, 9 Weese-Mayer D.E....Marazita M.L. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- ARIX and PHOX2B polymorphisms in patients with congenital superior oblique muscle palsy. (PubMed id 16049556)1, 9 Jiang Y....Yasuda T. (2005)
- The interaction between dHAND and Arix at the dopamine beta-hydroxylase promoter region is independent of direct dHAND binding to DNA. (PubMed id 14506227)1, 9 Rychlik J.L....Lewis E.J. (2003)
- Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cell s. (PubMed id 19573018)1, 9 Fan Y....Zhu M.Y. (2009)
- Phox2 and dHAND transcription factors select shared and unique target genes in the noradrenergic cell type. (PubMed id 16280598)1, 9 Rychlik J.L....Lewis E.J. (2005)
|
External Searches for PHOX2A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PHOX2A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PHOX2A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PHOX2A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PHOX2A | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/PHOX2A |
|
| | |
About This Section
| Patent Information for PHOX2A gene:
Search GeneIP for patents involving PHOX2A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PHOX2A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for PHOX2A | | OriGene shRNA RFP for PHOX2A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PHOX2A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PHOX2A | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PHOX2A | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHOX2A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHOX2A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PHOX2A | | OriGene Custom Protein Services for PHOX2A | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PHOX2A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PHOX2A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHOX2A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PHOX2A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHOX2A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHOX2A |
| |
 |  |  |  | |
| | | | Search Tocris compounds for PHOX2A |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | PHOX2A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHOX2A |
|  |  |  | | | | ThermoFisher Antibody for PHOX2A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHOX2A |
|
|
|
|
