PHKG2 Gene
protein-coding GIFtS: 66
GCID: GC16P030759
|
|
phosphorylase kinase, gamma 2 (testis)
| |
Aliases
for PHKG2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Phosphorylase Kinase, Gamma 2 (Testis)1 2 | | GSD9C2 5 | | Phosphorylase Kinase Subunit Gamma-22 3 | | Phosphorylase B Kinase Gamma Catalytic Chain, Liver/Testis Isoform2 | | PHK-Gamma-LT1 | | Phosphorylase B Kinase Gamma Catalytic Chain, Testis/Liver Isoform2 | | PHK-Gamma-T1 | | Phosphorylase Kinase, Gamma 2 (Testis/Liver)2 | | PSK-C32 3 | | Serine/Threonine-Protein Kinase PHKG22 | | EC 2.7.11.193 8 | | EC 2.7.118 |
Export aliases for PHKG2 gene to outside databasesPrevious GC identifers: GC16P030042 GC16P031248 GC16P030756 GC16P030795 GC16P030667 GC16P028322 |
Summaries
for PHKG2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PHKG2:
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includesthe skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both themuscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepaticisoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded bythree different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunitshave regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme oncalcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liverglycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in thisgene.(provided by RefSeq, Feb 2010)
UniProtKB/Swiss-Prot: PHKG2_HUMAN, P15735Function: Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation ofglycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulateglycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity)
Gene Wiki entry for PHKG2
|
Genomic Views
for PHKG2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PHKG2 gene promoter:
Max1 Pax-5 Lmo2 AP-4 Cdc5 E2F E2F-1 Ik-2 ARP-1 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for PHKG2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHKG2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.2PHKG2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P030759: view genomic region
(about GC identifiers)
Start:
|
30,759,591 bp from pter |
End:
|
30,772,497 bp from pter |
Size:
|
12,907 bases |
Orientation:
|
plus strand |
|
Proteins
for PHKG2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PHKG2_HUMAN, P15735 (See
protein sequence)Recommended Name: Phosphorylase b kinase gamma catalytic chain, liver/testis isoform Size: 406 amino acids; 46442 Da
Subunit: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 orPHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta iscalmodulin
1 PDB 3D structure from  and Proteopedia  for PHKG2:2Y7J (3D)
Secondary accessions: A8K0C7 B4DEB7 E9PEU3 P11800Alternative splicing: 2 isoforms: P15735-1 P15735-2 Explore the universe of human proteins at neXtProt for PHKG2: NX_P15735
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P15735
4/17 DME Specific Peptides for PHKG2 (P15735) (see all 17)
PHKG2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_000285.1 NP_001165903.1
ENSEMBL proteins: ENSP00000455607 ENSP00000455091 ENSP00000388571 ENSP00000329968 ENSP00000457359 ENSP00000454641 ENSP00000457194 Reactome Protein details: P15735
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
PHKG2 for ontologies About GeneDecksing
PHKG2 Antibody Products:
Assay Products for PHKG2: |
Protein
Domains /
Families
for PHKG2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PHKG2 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry P15735ProtoNet protein and cluster: P15735 1 Blocks protein family: IPB002291 Phosphorylase kinase family signature
UniProtKB/Swiss-Prot: PHKG2_HUMAN, P15735Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase familySimilarity: Contains 1 protein kinase domain |
Function
for PHKG2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PHKG2_HUMAN, P15735Function: Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation ofglycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulateglycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity)Catalytic activity: 2 ATP + phosphorylase b = 2 ADP + phosphorylase a Genatlas biochemistry entry for PHKG2:phosphorylase kinase,isoform gamma 2,testis,liver and other tissues,glycogen catabolism
Enzyme Numbers (IUBMB): EC 2.7.11.191 2 EC 2.7.112
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHKG2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHKG2 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): PHKG2 (NM_000294) | |  | Sino Biological Human cDNA Clone for PHKG2 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PHKG2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHKG2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHKG2 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
PHKG2 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for PHKG2:
|
Pathways & Interactions
for PHKG2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | G Protein Signaling Pathways | | | 2 | Activation of cAMP-Dependent PKA | | | 3 | Glycogen breakdown (glycogenolysis) | | | 4 | Glucose metabolism | | | 5 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for PHKG2
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for PHKG2
2  GeneGo (Thomson Reuters) Pathways for PHKG2
1  BioSystems Pathway for PHKG2
4 
Reactome Pathways for PHKG2
2 
Kegg Pathways (Kegg details for PHKG2):
PHKG2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PHKG2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 18)
5/18 Interacting proteins for PHKG2 (P157353 ENSP000003299684) via UniProtKB, MINT, STRING, and/or I2D (see all 18)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
PHKG2 for ontologies About GeneDecksing
|
Drugs & Compounds
for PHKG2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PHKG2 for compounds About GeneDecksing
 Browse Tocris compounds for PHKG2
2 HMDB Compounds for PHKG2 About this table
1 Novoseek chemical compound relationship for PHKG2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| glycogen |
54.6 |
2 |
9384616 (1), 8896567 (1) |
Search CenterWatch for drugs/clinical trials and news about PHKG2
|
Transcripts
for PHKG2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PHKG2 gene (2 alternative transcripts): NM_000294.2 NM_001172432.1 Unigene Cluster for PHKG2: Phosphorylase kinase, gamma 2 (testis) Hs.65735 [show with all ESTs]Unigene Representative Sequence: NM_00029411 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000563588(uc021tgo.1 uc002dzk.2) ENST00000565924 ENST00000424889
ENST00000564838 ENST00000328273 ENST00000563913 ENST00000565897 ENST00000563607
ENST00000569762(uc002dzl.1) ENST00000569684 ENST00000561712
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHKG2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHKG2 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): PHKG2 (NM_000294) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PHKG2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHKG2 |
Additional cDNA sequence: AB209055.1 AK055943.1 AK289492.1 AK293551.1 BC002541.2 M14503.1 M31606.1 21 DOTS entries: DT.40113268 DT.447728 DT.95241839 DT.120714203 DT.120714225 DT.97846037 DT.100797745 DT.91766646 DT.95241841 DT.99984344 DT.95269850 DT.120714004 DT.70103107 DT.91766651 DT.100730770 DT.120714177 DT.86853373 DT.91766648 DT.91946942 DT.99972962 DT.95269851 24/526 AceView cDNA sequences (see all 526): BU186404 BQ675195 BU145933 BM700215 BE739053 BX387296 BM541884 BI520337 BQ051446 BX644175 AA419088 BU176523 BM808047 BM724438 AA291854 AA588297 AA662809 BM543955 BU682683 H09771 BI858535 BX103840 AU140541 BU178824
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for PHKG2 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10a | · | 10b |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | - | | | | | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PHKG2
|
Expression
for PHKG2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PHKG2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACTGCATAT
About this image
See PHKG2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PHKG2
SOURCE GeneReport for Unigene cluster: Hs.65735
SABiosciences Expression via Pathway-Focused PCR Array including PHKG2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PHKG2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PHKG2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHKG2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHKG2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHKG2 |
Orthologs
for PHKG2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PHKG2 gene from 5/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
PHKG26 |
-- |
73(a) |
1 ↔ 1 |
GL343516.1(95738-102493) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.104362 |
Xenopus laevis transcribed sequence with moderate similarity more |
78.16(n) |
|
CA974135.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc558632 |
similar to phosphorylase kinase, gamma 2 (testis) |
76.69(n) |
|
393937 BC047191.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
PhK&ggr;3
PhKgamma1 |
embryonic morphogenesis protein
serine/threonine more3
Phosphorylase kinase gamma1 |
59(a)3
57.86(n)1
56.6(a)1 |
|
1 10D53
321201 NM_167296.21 NP_727548.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y50D7A.31 |
Protein Y50D7A.3 |
49.03(n)
42.34(a) |
|
190101 NM_064780.3 NP_497181.2 |
ENSEMBL Gene Tree for PHKG2 (if available)
TreeFam Gene Tree for PHKG2 (if available) |
Paralogs
for PHKG2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PHKG2 gene
- PHKG12
18/99 SIMAP similar genes for PHKG2 using alignment to 6 protein entries: PHKG2_HUMAN (see all proteins)
(see all similar genes):PHKG1 MAPK4 KSR1 CDK3 CDK12 MINK1
MAPK7 CDK11B BRSK2 AKT2 CDK10 MARK3
PKN1 MAP2K4 TLK2 STK38L NUAK1 MAPK3
PHKG2 for paralogs About GeneDecksing
|
Genomic Variants
for PHKG2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PHKG2 (30759591 - 30772497 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for PHKG2
2 CNVs: 30780 2209
1 Indel: 102245
Human Gene Mutation Database (HGMD): PHKG2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PHKG2 |
|
Disorders
/ Diseases
for PHKG2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PHKG2 for disorders About GeneDecksing
OMIM gene information: 172471
OMIM disorders: 613027
UniProtKB/Swiss-Prot: PHKG2_HUMAN, P15735
Defects in PHKG2 are a cause of glycogen storage disease type 9C (GSD9C) [MIM:613027]. A metabolic disordermanifesting in infancy with hepatomegaly, growth retardation, hypotonia, liver dysfunction, and elevated plasmaaminotransferases and lipids. These symptoms improve with age in most cases; however, some patients may develophepatic fibrosis or cirrhosis
7  diseases for PHKG2: About MalaCardsglycogen storage disease cirrhosis due to liver phosphorylase kinase deficiency hepatitis metabolic disorders
hypotonia malaria alcoholism
1 disease from the University of Copenhagen DISEASES database for PHKG2:Glycogen storage disease 2 Novoseek disease relationships for PHKG2 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| glycogen storage disease |
82.5 |
5 |
9384616 (2), 8896567 (2), 12930917 (1) |
| cirrhosis |
40.7 |
4 |
9384616 (2), 12930917 (1) |
Export disorders for PHKG2 gene to outside databases
|
Publications
for PHKG2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PHKG2 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with PHKG2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Messenger ribonucleic acid encoding an apparent isoform of phosphorylase kinase catalytic subunit is abundant in the adult testis. (PubMed id 2915644)1, 2, 3 Hanks S.K. (1989)
- Severe phenotype of phosphorylase kinase-deficient liver glycogenosis with mutations in the PHKG2 gene. (PubMed id 12930917)1, 2, 9 Burwinkel B....Kilimann M.W. (2003)
- Liver glycogenosis due to phosphorylase kinase deficiency: PHKG2 gene structure and mutations associated with cirrhosis. (PubMed id 9384616)1, 2, 9 Burwinkel B.... Kilimann M.W. (1998)
- Mutations in the testis/liver isoform of the phosphorylase kinase gamma subunit (PHKG2) cause autosomal liver glycogenosis in the gsd rat and in humans. (PubMed id 8896567)1, 2, 9 Maichele A.J.... Kilimann M.W. (1996)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure. (PubMed id 10487978)1, 2 Brushia R.J. and Walsh D.A. (1999)
- Isolation and characterization of transcribed sequences from a chromosome 16 hn-cDNA library and the physical mapping of genes and transcribed sequences using a high-resolution somatic cell panel of human chromosome 16. (PubMed id 8020963)1, 3 Whitmore S.A....Callen D.F. (1994)
- Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family. (PubMed id 2948189)1, 2 Hanks S.K. (1987)
- Glycogen storage disease type IX: High variability in clinical phenotype. (PubMed id 17689125)1, 9 Beauchamp N.J....Sharrard M. (2007)
|
External Searches for PHKG2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PHKG2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PHKG2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PHKG2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for PHKG2 gene:
Search GeneIP for patents involving PHKG2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for PHKG2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for PHKG2 | | OriGene shRNA RFP for PHKG2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PHKG2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PHKG2 | | | OriGene Protein Over-expression Lysate for PHKG2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PHKG2 | | OriGene 3'-UTR Clone for PHKG2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHKG2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHKG2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PHKG2 | | OriGene Custom Protein Services for PHKG2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PHKG2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PHKG2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHKG2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PHKG2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHKG2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHKG2 |
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| | | | Search Tocris compounds for PHKG2 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHKG2 |
|  |  |  | | | | ThermoFisher Antibodies for PHKG2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHKG2 |
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