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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PHKA1 Gene

protein-coding   GIFtS: 63
GCID: GC0XM071715

Phosphorylase Kinase, Alpha 1 (Muscle)


(Previous symbol: PHKA)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Phosphorylase Kinase, Alpha 1 (Muscle)1 2
PHKA1 2 3
Phosphorylase Kinase Alpha M Subunit2 3
Phosphorylase B Kinase Regulatory Subunit Alpha Skeletal Muscle Isoform2
Phosphorylase B Kinase Regulatory Subunit Alpha, Skeletal Muscle Isoform2
Phosphorylase Kinase, Alpha 1 (Muscle), Muscle Glycogenosis2

External Ids:    HGNC: 89251   Entrez Gene: 52552   Ensembl: ENSG000000671777   OMIM: 3118705   UniProtKB: P460203   

Export aliases for PHKA1 gene to outside databases

Previous GC identifers: GC0XM067527 GC0XM069035 GC0XM070033 GC0XM070667 GC0XM071583 GC0XM065553


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PHKA1 Gene:
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit
includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The
beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also
includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is
a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the
enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta
subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen
storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants
encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome
1.(provided by RefSeq, Feb 2010)

GeneCards Summary for PHKA1 Gene: 
PHKA1 (phosphorylase kinase, alpha 1 (muscle)) is a protein-coding gene. Diseases associated with PHKA1 include muscle glycogenosis, and muscle phosphorylase kinase deficiency, and among its related super-pathways are Glycogen Metabolism and Activation of cAMP-Dependent PKA. GO annotations related to this gene include phosphorylase kinase activity and calmodulin binding. An important paralog of this gene is PHKA2.

UniProtKB/Swiss-Prot: KPB1_HUMAN, P46020
Function: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin
I. The alpha chain may bind calmodulin

Gene Wiki entry for PHKA1 (Phosphorylase kinase, alpha 1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NT_011669.17  NC_018934.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PHKA1 gene promoter:
         HOXA9   HOXA9B   GATA-3   Pax-6   MIF-1   GATA-2   GATA-1   PPAR-gamma1   PPAR-gamma2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPHKA1 promoter sequence
   Search SABiosciences Chromatin IP Primers for PHKA1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHKA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq12-q13   Ensembl cytogenetic band:  Xq13.2   HGNC cytogenetic band: Xq12-q13

PHKA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PHKA1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM071715:  view genomic region     (about GC identifiers)

Start:
71,798,664 bp from pter      End:
71,934,167 bp from pter
Size:
135,504 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KPB1_HUMAN, P46020 (See protein sequence)
Recommended Name: Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform  
Size: 1223 amino acids; 137312 Da
Subunit: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1
or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is
calmodulin
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Secondary accessions: B7ZL05 B7ZL07 Q2M3D7
Alternative splicing: 3 isoforms:  P46020-1   P46020-2   P46020-3   

Explore the universe of human proteins at neXtProt for PHKA1: NX_P46020

Explore proteomics data for PHKA1 at MOPED 

Post-translational modifications:

  • UniProtKB: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is
    not methylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P46020

  • PHKA1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PHKA1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001116142.1  NP_001165907.1  NP_002628.2  

    ENSEMBL proteins: 
     ENSP00000362643   ENSP00000362646   ENSP00000362640   ENSP00000342469   ENSP00000441251  
    Reactome Protein details: P46020
    Human Recombinant Protein Products for PHKA1: 
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    Novus Biologicals PHKA1 Protein
    Novus Biologicals PHKA1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005886plasma membrane IEA--

    PHKA1 for ontologies           About GeneDecksing



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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR008734 PHK_A/B_su
     IPR011613 Glyco_hydro_15
     IPR012341 6hp_glycosidase
     IPR008928 6-hairpin_glycosidase-like

    Graphical View of Domain Structure for InterPro Entry P46020

    ProtoNet protein and cluster: P46020

    1 Blocks protein domain: IPB008734 Phosphorylase kinase alphabeta

    UniProtKB/Swiss-Prot: KPB1_HUMAN, P46020
    Similarity: Belongs to the phosphorylase b kinase regulatory chain family


    PHKA1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KPB1_HUMAN, P46020
    Function: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin
    I. The alpha chain may bind calmodulin
    Enzyme regulation: By phosphorylation of various serine residues. Allosteric regulation by calcium

         Genatlas biochemistry entry for PHKA1:
    phosphorylase kinase,alpha 1 subunit,muscle,glycogen catabolism

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds IEA--
    GO:0004689phosphorylase kinase activity TAS8226841
    GO:0005516calmodulin binding IEA--
         
    PHKA1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for PHKA1:
     Increased HPV18 LCR reporter a  Upregulation of Wnt/beta-caten 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Phka1):
     homeostasis/metabolism  muscle 

    PHKA1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PHKA1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PHKA1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PHKA1 
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    SwitchGear 3'UTR luciferase reporter plasmidPHKA1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for PHKA1 About   (see all 10)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Glycogen breakdown (glycogenolysis)
    Glycogen breakdown (glycogenolysis)0.34
    Glycogen Metabolism0.34
    2Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    PKA Signaling0.56
    cAMP Pathway0.77
    3Glucose metabolism
    Glucose metabolism0.50
    4MPS IIIC - Sanfilippo syndrome C
    Metabolism of carbohydrates0.48
    5Signal transduction cAMP signaling
    Signal transduction cAMP signaling0.44

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 EMD Millipore Pathways for PHKA1
        Development Beta-adrenergic receptors signaling via cAMP
    Signal transduction cAMP signaling

    4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for PHKA1
        PKA Signaling
    cAMP Pathway
    Activation of cAMP-Dependent PKA
    Alpha-Adrenergic Signaling

    2 GeneGo (Thomson Reuters) Pathways for PHKA1
        Development Beta-adrenergic receptors signaling via cAMP
    Signal transduction cAMP signaling

    1 BioSystems Pathway for PHKA1
        Glycogen Metabolism

    4        Reactome Pathways for PHKA1
        Metabolism of carbohydrates
    Glycogen breakdown (glycogenolysis)
    Metabolism
    Glucose metabolism


    2         Kegg Pathways  (Kegg details for PHKA1):
        Calcium signaling pathway
    Insulin signaling pathway

    UniProtKB/Swiss-Prot: KPB1_HUMAN, P46020
    Pathway: Glycan biosynthesis; glycogen metabolism


    PHKA1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PHKA1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/23 Interacting proteins for PHKA1 (P460203 ENSP000003626434) via UniProtKB, MINT, STRING, and/or I2D (see all 23)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKACAP176123, ENSP000003095914I2D: score=1 STRING: ENSP00000309591
    PHKG1ENSP000002973734STRING: ENSP00000297373
    PYGBENSP000002169624STRING: ENSP00000216962
    PYGMENSP000001641394STRING: ENSP00000164139
    GYG1ENSP000003407364STRING: ENSP00000340736
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0005976polysaccharide metabolic process ----
    GO:0005977glycogen metabolic process TAS7874115
    GO:0005980glycogen catabolic process TAS--
    GO:0006006glucose metabolic process TAS--

    PHKA1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PHKA1 (KPB1)

    1 HMDB Compound for PHKA1    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about PHKA1 / KPB1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PHKA1 gene (3 alternative transcripts): 
    NM_001122670.1  NM_001172436.1  NM_002637.3  

    Unigene Cluster for PHKA1:

    Phosphorylase kinase, alpha 1 (muscle)
    Hs.201379  [show with all ESTs]
    Unigene Representative Sequence: NM_002637
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373542(uc010nll.3) ENST00000373545(uc011mqi.2) ENST00000373539
    ENST00000339490(uc004eax.4 uc004eay.4) ENST00000541944
    miRNA
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    8/39 QIAGEN miScript miRNA Assays for microRNAs that regulate PHKA1 (see all 39):
    hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-136 hsa-miR-15a hsa-miR-372 hsa-miR-124 hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidPHKA1 3' UTR sequence
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PHKA1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHKA1
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHKA1

    Additional mRNA sequence: 

    BC104944.1 BC143499.1 BC143501.1 BX647542.1 X73874.1 X73878.1 

    5 DOTS entries:

    DT.211310  DT.310007  DT.91748065  DT.121295709  DT.99965577 

    24/91 AceView cDNA sequences (see all 91):

    BF222834 CK821186 BI963942 BX647542 X73878 AU125639 BI964104 BX116981 
    BQ576295 BX950979 AA247817 BE619283 AU125725 AA719684 R30663 BM824020 
    BX113174 AA989233 AI524313 AL699144 AA582145 BX499537 AW833974 BF475654 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PHKA1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGGTGCCA
    PHKA1 Expression
    About this image


    See PHKA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PHKA1

    SOURCE GeneReport for Unigene cluster: Hs.201379

    UniProtKB/Swiss-Prot: KPB1_HUMAN, P46020
    Tissue specificity: Muscle specific. Isoform 1 is predominant in vastus lateralis muscle. Isoform 2 predominates
    slightly in heart, and it predominates clearly in the other tissues tested

        SABiosciences Expression via Pathway-Focused PCR Array including PHKA1: 
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHKA1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PHKA1 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Phka11 , 5 phosphorylase kinase alpha 11, 5 91.39(n)1
    94.85(a)1
      X (45.47 cM)5
    186791  NM_008832.21  NP_032858.21 
     1025139755 
    chicken
    (Gallus gallus)
    Aves PHKA11 phosphorylase kinase, alpha 1 (muscle) 72.95(n)
    78.6(a)
      422181  XM_003641090.1  XP_003641138.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    PHKA16
    phosphorylase kinase, alpha 1 (muscle)
    90(a)
    68(a)
    possible ortholog
    1 ↔ 1
    GL344585.1(21-12440)
    GL343686.1(255036-268943)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.319442 Xenopus laevis transcribed sequence with weak similarity more 75.89(n)    CF522108.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufl37h012 wufl37h01 72.05(n)   386818  57093902 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG77663 phosphorylase kinase, regulator 45(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea C14B9.83 Phosphorylase kinase 40(a)   III(8211651-8216537)   --


    ENSEMBL Gene Tree for PHKA1 (if available)
    TreeFam Gene Tree for PHKA1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PHKA1 gene
    PHKA22  PHKB2  
    2 SIMAP similar genes for PHKA1 using alignment to 3 protein entries:     KPB1_HUMAN (see all proteins):
    PHKA2    PHKB

    PHKA1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PHKA1
    PGOHUM00000244096


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1210/1505 SNPs in PHKA1 are shown (see all 1505)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0208564
    Glycogen storage disease 9D (GSD9D)4--see VAR_0208562 D V mis40--------
    rs1861953571,2
    --71803968(+) GGTGGC/TGCATG 3 -- ds50010--------
    rs1890027721,2
    --71804181(+) AAAATA/GTTCCC 3 -- ds50010--------
    rs1822878661,2
    --71804811(+) TAAAAA/GTGACC 3 -- ut310--------
    rs1389013791,2
    --71804895(+) CTGTCA/CTCTCT 3 -- ut310--------
    rs1873669091,2
    --71805078(+) GTAGGA/GAGTTA 3 -- ut310--------
    rs1429251521,2
    C--71805248(+) TCACAC/TCCCTT 3 -- ut310--------
    rs1907945681,2
    --71805366(+) ACACAC/TACACA 3 -- ut310--------
    rs1826435501,2
    --71805745(+) ATTCCC/TTCTCT 3 -- ut310--------
    rs1445386261,2
    --71805819(+) GCTCCA/GGGCTC 3 -- ut310--------
    rs723182391,2
    C--71805993(+) GACAC-/AGAGAGG 3 -- ut310--------
    rs1125202751,2
    C,F--71806062(+) TGAGAT/CGAAGC 6 -- int11Minor allele frequency- C:0.00CSA 1
    rs1484657181,2
    C--71806123(+) ACGTAG/TAATAG 3 -- ut310--------
    rs1864019221,2
    --71806161(+) ATTTAA/GCAATT 3 -- ut310--------
    rs1899933121,2
    --71806550(+) ACATTG/TTAGTT 3 -- ut310--------
    rs1408655221,2
    F--71806754(+) AGATGC/GGGGAT 6 P A mis11Minor allele frequency- G:0.00NA 4550
    rs2015737071,2
    C--71806772(+) CAACAC/TGGTAT 6 M V mis10--------
    rs1448132381,2
    C,F--71806784(+) ATCTGC/TGCCAA 6 T A mis11Minor allele frequency- T:0.00NA 4548
    rs1998005731,2
    --71806863(+) TAAAG-/TCCTGA 3 -- int10--------
    rs59121051,2
    C,F,H--71807154(+) TGACTT/CCTTCT 3 -- int19Minor allele frequency- C:0.83NS EA NA WA 554
    rs346988771,2
    F--71807176(+) TTTCAG/CCTTGT 3 -- int12Minor allele frequency- C:0.50NA 4
    rs2007293471,2
    --71807417(+) GAAAA-/TTTTTT 3 -- int10--------
    rs1508380931,2
    --71807500(+) AATAGA/TTTGTA 3 -- int10--------
    rs1396296561,2
    C--71807685(+) TTATTA/GAGTCC 3 -- int10--------
    rs1875165551,2
    --71807938(+) GTGACC/TGTGGC 3 -- int10--------
    rs1489815221,2
    C,F--71808082(+) CTTCCG/AATGCT 6 /I syn11Minor allele frequency- A:0.00NA 4548
    rs1438025111,2
    F--71808167(+) GTACAC/TGATTC 6 H R mis11Minor allele frequency- T:0.00NA 4536
    rs1465531571,2
    --71808309(+) ACTGTA/GGCCAT 3 -- int10--------
    rs1904916371,2
    --71808504(+) AGTACC/TTATAG 3 -- int10--------
    rs1116448641,2
    C--71808741(-) TCAGCA/GATTCA 6 -- int11Minor allele frequency- G:0.00CSA 1
    rs791521271,2
    C--71808821(-) AATCCA/GTCTGG 6 -- int13Minor allele frequency- G:0.00NA CSA 5
    rs1838916191,2
    --71808837(+) CTTGGA/GTTCAA 3 -- int10--------
    rs734774781,2
    C--71808970(+) ACACAC/ACAACA 6 -- int11Minor allele frequency- A:0.50CSA 2
    rs778802061,2
    C--71808973(+) AAATTC/TAAAAA 3 -- int10--------
    rs1889059271,2
    C--71809027(+) ATGTAC/TTATTA 3 -- int10--------
    rs1923919051,2
    --71809056(+) TCTTGC/TGTAAA 3 -- int10--------
    rs1843533031,2
    --71809057(+) CTTGCA/GTAAAG 3 -- int10--------
    rs26171171,2
    C--71809109(+) gatgcA/Gaggct 6 -- int11Minor allele frequency- G:0.00NA 2
    rs1867177821,2
    C--71809466(+) TGGAAC/TCCGGG 3 -- int10--------
    rs1918865751,2
    --71809502(+) ACAACC/TACTGG 3 -- int10--------
    rs1401739921,2
    --71809565(+) AGGACA/GGGAGA 3 -- int10--------
    rs1841327491,2
    C--71809840(+) TCAGTA/CACATA 3 -- int10--------
    rs1892456381,2
    --71810151(+) TCATCC/TTCTAC 3 -- int10--------
    rs169884681,2
    C,F,H--71810211(+) TCCCAA/CATATT 3 -- int111--NA NS EA CSA 1233
    rs1458118721,2
    C--71810249(+) TAGGTC/TGCACG 3 -- int10--------
    rs1996662231,2
    C--71810364(+) TTTTT-/AAACAC 3 -- int10--------
    rs113889611,2
    C--71810366(+) TTTAA-/ACACTT 3 -- int10--------
    rs37887941,2
    C--71810420(+) CACAAC/TGTGCA 3 -- int11Minor allele frequency- T:0.00NA 2
    rs37887951,2
    C--71810616(+) GAACAC/TGCGGT 3 -- int12Minor allele frequency- T:0.00NA 4
    rs1816029291,2
    --71810693(+) CAGATA/GCATAT 3 -- int10--------
    rs1855896961,2
    --71810805(+) TGTGGC/TGTTCT 3 -- int10--------
    rs1904954471,2
    C--71810810(+) TGTTCG/TAAGTA 3 -- int10--------
    rs1809495061,2
    --71811022(+) TGCCAC/TGTTAT 3 -- int10--------
    rs1851793651,2
    --71811760(+) ACCCTC/TGTGTA 3 -- int10--------
    rs1896846881,2
    --71811761(+) CCCTCA/GTGTAG 3 -- int10--------
    rs1813560041,2
    --71811791(+) CTACTA/TGGGGC 3 -- int10--------
    rs1852826981,2
    --71812248(+) ACAAAA/CTTCTC 3 -- int10--------
    rs1916189321,2
    --71812331(+) AACTAA/GAATAA 3 -- int10--------
    rs1835458211,2
    C--71812367(+) CCTGAA/TGGAGC 3 -- int10--------
    rs1420902781,2
    --71812382(+) AACCAC/TGGCAC 3 -- int10--------
    rs1457470521,2
    C--71812402(+) GTGACA/GCACGC 3 -- int10--------
    rs1386862291,2
    --71812418(+) CTTCAA/GTAACC 3 -- int10--------
    rs1428816671,2
    --71812499(+) GTGTAA/GACAAA 3 -- int10--------
    rs1888728601,2
    --71812521(+) AGAAAC/TGAACA 3 -- int10--------
    rs1924228761,2
    --71812685(+) TCAAAC/TTCAGG 3 -- int10--------
    rs126884801,2
    C,H--71812872(+) tctacA/Gagcca 3 -- int12Minor allele frequency- G:0.00NA 4
    rs1380874211,2
    --71812928(+) TTCAAC/TGCAGA 3 -- int10--------
    rs1838111311,2
    --71813064(+) AAACAC/TGGAAA 3 -- int10--------
    rs1869421381,2
    --71813116(+) TAAAGA/GCTATC 3 -- int10--------
    rs355005461,2
    C--71813191(+) TGAAC-/TTTTTT 6 -- int10--------
    rs1494993171,2
    C--71813344(+) AAATAA/TAGGGA 3 -- int10--------
    rs1914052391,2
    --71813555(+) AAAGCA/CAGTCC 3 -- int10--------
    rs1841771411,2
    --71813602(+) TAATAA/GTGGCA 3 -- int10--------
    rs1440545641,2
    --71813739(+) AACCAA/TCGGAA 3 -- int10--------
    rs1395908671,2
    --71813740(+) ACCAAC/TGGAAT 3 -- int10--------
    rs1870157331,2
    --71813858(+) TCAGAC/TCACAG 3 -- int10--------
    rs1428810611,2
    --71813863(+) CCACAG/TTGCAA 3 -- int10--------
    rs1929328611,2
    C--71813981(+) GAAATA/GAAGGT 3 -- int10--------
    rs1460578261,2
    C--71814080(+) AAATGC/TCCACA 3 -- int10--------
    rs1851646311,2
    --71814255(+) GAATCA/CAGGAG 3 -- int10--------
    rs1898961761,2
    C--71814423(+) CACCTC/TTATGC 3 -- int10--------
    rs1825685991,2
    --71814544(+) AAATTA/GAGGCA 3 -- int10--------
    rs1846994511,2
    --71814674(+) AAAGAC/TGGAAT 3 -- int10--------
    rs1881695001,2
    --71814775(+) CCTGAC/TGAACA 3 -- int10--------
    rs1807033451,2
    --71814869(+) TTCATC/TCCTGG 3 -- int10--------
    rs1400492761,2
    --71815046(+) ACATAC/TCTCAA 3 -- int10--------
    rs1422748221,2
    C--71815272(+) TTGCAC/GATGAC 3 -- int10--------
    rs2009600611,2
    C--71815290(+) TATATC/TTAGAA 3 -- int10--------
    rs2019364671,2
    C--71815304(+) CCCATC/TGTCTC 3 -- int10--------
    rs2005367061,2
    C--71815325(+) CTCCTC/TAAGCT 3 -- int10--------
    rs1394200171,2
    C--71815331(+) AAGCTA/GATAAG 3 -- int10--------
    rs2022015511,2
    C--71815361(+) GGATAC/GAAAAT 3 -- int10--------
    rs2014374771,2
    C--71815373(+) AATGTA/GCAAAA 3 -- int10--------
    rs1855448751,2
    --71815397(+) CTATAC/TACTAA 3 -- int10--------
    rs1913219511,2
    --71815729(+) AGCCCA/GCATTG 3 -- int10--------
    rs1812058581,2
    --71816074(+) GTTAGA/GCCTAA 3 -- int10--------
    rs1420503501,2
    C--71816269(+) AATTTC/TTGCAA 3 -- int10--------
    rs1871193641,2
    --71816384(+) AACAGA/TCACTT 3 -- int10--------
    rs1915349901,2
    --71816385(+) ACAGAA/CACTTC 3 -- int10--------
    rs1835523901,2
    --71816458(+) CAGAGA/TAATGC 3 -- int10--------
    rs1443464311,2
    --71816468(+) CAAATC/GAAAAC 3 -- int10--------
    rs1477702131,2
    --71816551(+) AGGATA/GTGGAT 3 -- int10--------
    rs1488107491,2
    --71816718(+) ACTATA/GAAGAT 3 -- int10--------
    rs1862868041,2
    --71816737(+) ATGTAA/TGTTTA 3 -- int10--------
    rs1898729291,2
    --71816747(+) ATTGCA/GGCACT 3 -- int10--------
    rs1821455151,2
    --71816826(+) GGCACA/TTATAT 3 -- int10--------
    rs1880665221,2
    --71816891(+) ACATAA/GACGAA 3 -- int10--------
    rs1929670391,2
    --71816984(+) ACAATA/GAGAAC 3 -- int10--------
    rs2000827971,2
    --71817192(+) AAAAG-/AAAAAA 3 -- int10--------
    rs59121071,2
    C,F,A,H--71817326(+) ACAAAA/GCTATC 3 -- int116Minor allele frequency- G:0.05NS EA WA NA CSA 1087
    rs1480512661,2
    --71817741(+) CTGTAG/TGAGCA 3 -- int10--------
    rs1128966791,2
    C,F--71817926(+) CTGTCT/CTTGGA 3 -- int11Minor allele frequency- C:0.00NA 1
    rs1888499431,2
    --71818238(+) TTCATA/CCAAGA 3 -- int10--------
    rs1928127411,2
    --71818445(+) ATGTAA/TCACAA 3 -- int10--------
    rs2015549651,2
    --71818696(+) CAAAAA/CTGAGA 3 -- int10--------
    rs1847439341,2
    C--71818798(+) TTCTTC/TGGCGT 6 Q R mis10--------
    rs1511201871,2
    C--71818825(+) GACTAT/CCTTTA 6 /D /G mis11Minor allele frequency- C:0.00NA 4550
    rs2002832291,2
    --71818826(+) ACTATA/CTTTAG 6 D Y mis10--------
    rs1402251871,2
    F--71818848(+) TCATAT/CGCACT 6 /A syn11Minor allele frequency- C:0.00NA 4550
    rs1891939791,2
    --71819165(+) TCACCA/GTGTTA 3 -- int10--------
    rs1128597221,2
    C--71819258(+) ACACCT/CGGCCC 3 -- int11Minor allele frequency- C:0.00CSA 1
    rs59588051,2
    H--71819470(+) ACAttC/Gttagc 3 -- int14Minor allele frequency- G:0.00NS EA 418
    rs1447531311,2
    C--71819504(+) GTTAAA/GCTTCT 3 -- int10--------
    rs1387150451,2
    C--71819761(+) TTATGA/GGATGC 3 -- int10--------
    rs46141271,2
    C--71819812(+) cctatA/Tttaaa 3 -- int11Minor allele frequency- T:0.00NA 2
    rs1428502791,2
    --71819864(+) TGAAGA/GCAATA 3 -- int10--------
    rs1460778381,2
    --71820097(+) GGATTA/GTAAGG 3 -- int10--------
    rs1913807571,2
    --71820125(+) ATATGC/TGGACA 3 -- int10--------
    rs1388724341,2
    --71820301(+) GGGCAA/TATGGC 3 -- int10--------
    rs1837327891,2
    --71820429(+) AATAAA/TCAAAC 3 -- int10--------
    rs583433171,2
    C,F--71820510(+) AATTAT/ATACTA 3 -- int11Minor allele frequency- A:0.50WA 2
    rs1446920981,2
    --71820578(+) GGCCAA/GTATTA 3 -- int10--------
    rs1891192381,2
    --71820579(+) GCCAAC/TATTAC 3 -- int10--------
    rs1815766151,2
    --71820642(+) CTTTAG/TGAATA 3 -- int10--------
    rs1863315431,2
    --71820737(+) TTCCAA/GAAATT 3 -- int10--------
    rs1902426481,2
    --71820763(+) ATCTGA/GACATC 3 -- int10--------
    rs1814574821,2
    --71820893(+) CTAGGA/CACAGA 3 -- int10--------
    rs1120213991,2
    C--71821152(+) ACCATC/TGTTAA 6 -- int11Minor allele frequency- T:0.00CSA 1
    rs1864863761,2
    C--71821251(+) TTAAAA/TTTTAC 3 -- int10--------
    rs1485806221,2
    --71821391(+) TGACCA/GTGGTT 3 -- int10--------
    rs1909178361,2
    --71821459(+) GTACAC/GTGTTG 3 -- int10--------
    rs1429946711,2
    --71821486(+) CTGCAG/TCCGCT 3 -- int10--------
    rs1832974631,2
    --71821987(+) CTAGAA/GATCTA 3 -- int10--------
    rs1862158061,2
    --71822043(+) TAAAAA/TTTTTT 3 -- int10--------
    rs1472960191,2
    C--71822421(+) CATTCA/GTATTT 3 -- int10--------
    rs1907743661,2
    --71822489(+) GCTATA/CAAAAC 3 -- int10--------
    rs1832900301,2
    --71822545(+) TAGATC/TGATGG 3 -- int10--------
    rs1409666511,2
    C--71822564(+) AGGGAA/GTTCAA 3 -- int10--------
    rs1878228261,2
    --71822614(+) GGACGC/TCAAGA 3 -- int10--------
    rs1921593851,2
    --71822726(+) AAAATA/TAAGCC 3 -- int10--------
    rs1448234851,2
    --71822738(+) ATTGTA/GCAGAA 3 -- int10--------
    rs1827942181,2
    --71822952(+) AGAGTA/TTTGAT 3 -- int10--------
    rs23692151,2
    C,F,A,H--71823024(+) TTTATT/GAGGTT 3 -- int120Minor allele frequency- G:0.51NS EA NA WA CSA 2080
    rs44095171,2
    C,F,H--71823069(+) tgcagA/Ggtgac 3 -- int113Minor allele frequency- G:0.89NS EA NA WA CSA 1299
    rs1873021661,2
    --71823128(+) TGACCA/CATGAC 3 -- int10--------
    rs1926491791,2
    --71823396(+) TAAACC/TGTAGC 3 -- int10--------
    rs48259431,2
    C,F,A,H--71823425(+) CTGAGA/TTCTAT 3 -- int14Minor allele frequency- T:0.33NS EA 418
    rs2011458801,2
    --71823425(+) CTGAG-/ATCTAT 3 -- int10--------
    rs48259441,2
    C,A--71823426(+) TGAGAC/TCTATG 3 -- int10--------
    rs2017872441,2
    --71823426(+) GAGAT-/CCTATG 3 -- int10--------
    rs1921402711,2
    --71823432(+) CTATGA/GGTCTT 3 -- int10--------
    rs726300531,2
    C--71823610(+) TGATTA/GACAAA 3 -- int10--------
    rs1491074651,2
    --71824061(+) ACATGA/TCTGGC 3 -- int10--------
    rs1449319171,2
    --71824149(+) AACATA/TTGTCC 3 -- int10--------
    rs735003371,2
    C,F--71824203(+) AGCAGC/ACAAAA 3 -- int11Minor allele frequency- A:0.50WA 2
    rs1849100591,2
    --71824447(+) GAAAAG/TAACTT 3 -- int10--------
    rs777593571,2
    F--71824502(+) CAATGC/TAAAAA 3 -- int11Minor allele frequency- T:0.00NA 2
    rs1816682541,2
    --71824725(+) AATTTA/TCTTCT 3 -- int10--------
    rs1862018871,2
    --71824756(+) TGTGGA/TTATGA 3 -- int10--------
    rs59587681,2
    C,F,H--71824973(+) TGTAAG/ACTTCA 3 -- int14Minor allele frequency- A:0.00NS EA 400
    rs59588061,2
    C,F,A,H--71824979(+) CTTCAT/CGAGGG 3 -- int18Minor allele frequency- C:0.46NS EA NA WA CSA 425
    rs1890048591,2
    --71825053(+) TAAATC/GAATTC 3 -- int10--------
    rs1820491941,2
    --71825146(+) TCATCC/TGCAGT 3 -- int10--------
    rs3764975441,2
    C--71825343(+) GATTA-/TTTTTT 3 -- int10--------
    rs1869950571,2
    C--71825402(+) GCACAC/TGTGAA 3 -- int10--------
    rs70542301,2
    C,F,A,H--71825463(+) AATCTA/GTACCC 3 -- int131Minor allele frequency- G:0.37NS NA EA WA 2714
    rs1910720921,2
    C--71825484(+) CACCAC/TTGGAC 3 -- int10--------
    rs732183721,2
    C,F--71825602(+) GTAGTC/TAGCAC 3 -- int10--------
    rs2005901701,2
    --71825687(+) ATAAT-/GTTTTT 3 -- int10--------
    rs1866539711,2
    --71825986(+) ATAATG/TAACTT 3 -- int10--------
    rs1902250391,2
    --71826083(+) CAATGC/TAACTA 3 -- int10--------
    rs59121081,2
    C--71826133(+) AGGAAA/TATATT 3 -- int10--------
    rs1503990701,2
    C--71826135(+) GAAAAC/TATTCA 3 -- int10--------
    rs1824834371,2
    --71826157(+) TTATTC/TGAGAA 3 -- int10--------
    rs173121641,2
    C,F,H--71826305(+) CTAAAC/TGGTTT 3 -- int115--NA NS EA 1828
    rs1875180501,2
    --71826467(+) AGTGCC/TAAAAA 3 -- int10--------
    rs1904959601,2
    --71826648(+) AACTTG/TGAGAT 3 -- int10--------
    rs1496390931,2
    --71826720(+) TTCCTG/TGTATA 3 -- int10--------
    rs1473129031,2
    --71826825(+) TTTCTC/TCCTCT 3 -- int10--------
    rs1840556081,2
    --71826896(+) AAGCAC/TGGTAA 3 -- int10--------
    rs1886080201,2
    --71827016(+) GAATTC/TATAGC 3 -- int10--------
    rs1927419161,2
    --71827256(+) GAAGTA/GCACAA 3 -- int10--------
    rs1841957641,2
    --71827523(+) TTGTTA/GTCTTA 3 -- int10--------
    rs1867046371,2
    --71827542(+) AAGGCC/TATGAG 3 -- int10--------
    rs1995300281,2
    --71827657(+) CTGAAA/TCATAA 3 -- int10--------
    rs1425016121,2
    C--71827875(+) ACTGAC/TATTTG 6 I V mis11Minor allele frequency- T:0.00NA 4544
    rs1841361581,2
    C--71827899(+) AACTAC/TGTAGT 3 -- int10--------
    rs1890872391,2
    --71828070(+) TACAAA/GTTTGT 3 -- int10--------
    rs1814740731,2
    --71828456(+) TATGGA/GTTGCT 3 -- int10--------
    rs1431713101,2
    --71828557(+) ATATAC/TCATTT 3 -- int10--------
    rs1475157361,2
    --71828593(+) TCTTGC/TTCCAG 3 -- int10--------
    rs1484230201,2
    --71828656(+) AGGTTC/TCTGTG 3 -- int10--------
    rs59121091,2
    C--71828966(+) ATTACA/GAAATA 3 -- int10--------
    rs1857502531,2
    --71829161(+) CTGGAA/GGCCAT 3 -- int10--------
    rs66260151,2
    H--71829239(+) TAATAG/CAGACT 3 -- int14Minor allele frequency- C:0.00NS EA 418
    rs1509286761,2
    --71829371(+) TGTGCA/GAGCAG 3 -- int10--------
    rs1394383541,2
    C--71829383(+) TATGAC/TGACAT 3 -- int10--------
    rs1902775831,2
    --71829582(+) GAAGAC/TAAAGG 3 -- int10--------
    rs1823069571,2
    --71829895(+) GCTTCA/GGGGAA 3 -- int10--------
    rs1861023821,2
    --71829965(+) TCTTCC/TCCAGA 3 -- int10--------
    rs128551271,2
    H--71830187(+) ATTTAA/CCAGAA 3 -- int14Minor allele frequency- C:0.00NS EA 418
    rs1431791641,2
    --71830237(+) TTTCTA/GTGCCA 3 -- int10--------
    rs1467460071,2
    --71830483(+) ATTCAA/GTCATG 3 -- int10--------
    rs1896868471,2
    --71830557(+) AGACGC/TTCCAC 3 -- int10--------
    rs283760841,2
    --71830590(+) TGTCTA/G/TTCACA 3 -- int10--------
    rs1404303021,2
    --71830600(+) ACTCAA/GATACT 3 -- int10--------
    rs1852719551,2
    --71830836(+) CCAAAC/TTCTAT 3 -- int10--------
    rs2015268191,2
    --71830928(+) TTGCCA/GTAACT 6 T M mis10--------
    rs2008358181,2
    --71831009(+) CTAGAA/TATACC 6 Y F mis10--------
    rs1905307281,2
    C--71831069(+) CTCACA/GATGCC 3 -- int10--------
    rs1832909281,2
    C--71831248(+) TAAGGA/GAAAAG 3 -- int10--------
    rs1891320701,2
    --71831428(+) CCATAA/TCAACT 3 -- int10--------
    rs1920511231,2
    --71831878(+) CCTACA/GATGGA 3 -- int10--------
    rs1454310231,2
    C--71831950(+) TTGATA/TTTCTA 3 -- int10--------
    rs1839933981,2
    --71831984(+) CACACA/GCACAC 3 -- int10--------
    rs1869442791,2
    --71832351(+) TACACC/TCTTTC 3 -- int10--------
    rs1450264251,2
    --71832423(+) TACAAC/GATCTT 3 -- int10--------
    rs1914097451,2
    --71832473(+) CTCCAA/CCCCCA 3 -- int10--------
    rs1842130991,2
    --71832482(+) CAACGC/TCCATA 3 -- int10--------
    rs1870479501,2
    --71832520(+) GTAACC/TATCAT 3 -- int10--------
    rs1931764991,2
    --71832654(+) ATCCAC/TGTTGT 3 -- int10--------
    rs1489533201,2
    --71832661(+) TTGTTA/GCAAAT 3 -- int10--------
    rs1852835891,2
    --71832691(+) TGTGTC/TTGAAT 3 -- int10--------
    rs1901879551,2
    --71832850(+) TTTGGA/GTATAT 3 -- int10--------
    rs1481136201,2
    C--71833010(+) TGTTAC/TTGCCT 3 -- int10--------
    rs1823136721,2
    --71833107(+) TGAGCA/GCCTTT 3 -- int10--------
    rs1856827491,2
    --71833471(+) CCTTTA/GCAAAA 3 -- int10--------
    rs1881769411,2
    --71833624(+) CTTTAC/TTCTTC 3 -- int10--------
    rs1806967141,2
    --71833665(+) TCCCTA/GTACCC 3 -- int10--------
    rs1437918691,2
    C--71833669(+) TATACA/CCACCA 3 -- int10--------
    rs66260161,2
    C,F,H--71833676(+) accacG/Agctgg 3 -- int14Minor allele frequency- A:0.02NS EA 418
    rs1393185841,2
    --71834050(+) TCTAGC/TTGATG 3 -- int10--------
    rs1433441101,2
    C--71834189(+) AAGCCC/TGCGGT 3 -- int10--------
    rs1508737471,2
    --71834296(+) GGAAGG/TAGTAT 3 -- int10--------
    rs1855281711,2
    --71834702(+) TCCCAA/GCCCCA 3 -- int10--------
    rs1884249381,2
    --71834742(+) AGCCTA/GTCTTA 3 -- int10--------
    rs1812159801,2
    --71835064(+) TACTAC/TTCTGT 3 -- int10--------
    rs18830701,2
    C,F,O,H--71835145(+) TGAACA/CTATGT 3 -- int120Minor allele frequency- C:0.28NA EA MN NS 2406
    rs1439199151,2
    --71835352(+) TTATCA/GTTTCT 3 -- int10--------
    rs1869157441,2
    --71835512(+) TCATCG/TATCTC 3 -- int10--------
    rs1917961641,2
    --71835643(+) ATGGAG/TTACAT 3 -- int10--------
    rs1486425131,2
    --71835780(+) AGATTC/TACAAC 3 -- int10--------
    rs1431358571,2
    --71835822(+) GACACC/TAAATA 3 -- int10--------
    rs1840827671,2
    --71835922(+) CTAGTA/GTCCAT 3 -- int10--------
    rs1863080341,2
    --71836030(+) TAACAC/TAGTGC 3 -- int10--------
    rs1466742731,2
    --71836277(+) GCTGGA/TTCCCA 3 -- int10--------
    rs1899148461,2
    --71836358(+) TTCCCA/GCTAAT 3 -- int10--------
    rs1393962781,2
    --71836380(+) GTTTCA/CCTTTC 3 -- int10--------
    rs1441725261,2
    C--71836610(+) AGCACA/GCTTAT 3 -- int10--------
    rs1445830351,2
    C,F--71836693(+) AAATGT/CATCGG 6 /Y /C mis11Minor allele frequency- C:0.00NA 4526
    rs1398036291,2
    C,F--71836714(+) AGTGAC/TGAATT 6 H R mis11Minor allele frequency- T:0.00NA 4534
    rs617324991,2
    C,F--71836743(+) AGCTCG/AGTAAG 6 /T syn12Minor allele frequency- A:0.00NS NA 4568
    rs1408032081,2
    --71836875(+) TCAGTA/GTTATA 3 -- int10--------
    rs1867062451,2
    --71837116(+) CACTGC/TAAGGA 3 -- int10--------
    rs1927780171,2
    --71837152(+) GGAAAA/CAATGT 3 -- int10--------
    rs603538701,2
    C,F--71837381(+) ATCAGG/ATTGTC 3 -- int11Minor allele frequency- A:0.00WA 2
    rs66246201,2
    H--71837637(+) cattaA/Tcttgt 3 -- int14Minor allele frequency- T:0.00NS EA 416
    rs1832520651,2
    --71837780(+) GAAGTA/CCTGAT 3 -- int10--------
    rs1452284341,2
    --71837788(+) GATACA/GTGTTA 3 -- int10--------
    rs1424543571,2
    --71837800(+) AACACA/GGATGA 3 -- int10--------
    rs1885699031,2
    --71837832(+) ATGAAA/GGAAGC 3 -- int10--------
    rs1463231931,2
    C--71838084(+) AAAATA/GCCTAT 3 -- int10--------
    rs1930215021,2
    --71838104(+) TATCAA/GTTCGA 3 -- int10--------
    rs1847337421,2
    --71838340(+) GCAACA/GATTTC 3 -- int10--------
    rs1891851171,2
    --71838449(+) TAAGGC/TAAAAG 3 -- int10--------
    rs1913553171,2
    --71838465(+) TACCTA/GATTTC 3 -- int10--------
    rs1130671711,2
    C--71839001(+) AGGAT-/ACACACA 3 -- int11Minor allele frequency- AC:0.00CSA 2
    rs1390718081,2
    --71839147(+) AACCAC/TAGGAA 3 -- int10--------
    rs1837147901,2
    --71839229(+) AAAAAA/TATCAG 3 -- int10--------
    rs726300541,2
    C--71839240(+) TGAGCA/GAAAGT 3 -- int10--------
    rs1893915601,2
    --71839377(+) TCCAAC/TCAAGC 3 -- int10--------
    rs1438432561,2
    --71839408(+) GCAATA/GGGACT 3 -- int10--------
    rs126870171,2
    C,F,H--71839792(+) tttttC/Gagaaa 3 -- int15Minor allele frequency- G:0.00NS EA NA 424
    rs1481696141,2
    --71839832(+) GGATCA/GTGTCT 3 -- int10--------
    rs44020101,2
    H--71839861(+) gttcaG/Aaaaaa 3 -- int14Minor allele frequency- A:0.00NS EA 416
    rs1419279231,2
    --71839876(+) ATATGC/TGTGTG 3 -- int10--------
    rs1506730111,2
    --71839902(+) GATGAC/TATCAA 3 -- int10--------
    rs1865258981,2
    --71839908(+) ATCAAC/TGTGAA 3 -- int10--------
    rs2007056171,2
    C--71839930(+) AGAGA-/GATTAAA 3 -- int10--------
    rs1491466061,2
    C--71840303(+) GGAAGA/GGCAAT 3 -- int10--------
    rs1899969301,2
    --71840340(+) ATAGAA/GGATTT 3 -- int10--------
    rs1416770521,2
    C--71840354(+) TTTGGC/TCAATG 3 -- int10--------
    rs774485561,2
    C--71840669(+) AAATAA/GCATAT 3 -- int10--------
    rs1816642921,2
    --71840697(+) CCTAAC/TGGCAG 3 -- int10--------
    rs1865100741,2
    --71840714(+) CAGCAA/GAACCC 3 -- int10--------
    rs1911475241,2
    --71840793(+) ACTTCA/GGAAAT 3 -- int10--------
    rs1833196671,2
    --71840885(+) GGGAGC/TTCTTC 3 -- int10--------
    rs1440975911,2
    --71840921(+) AATAAC/TATGAA 3 -- int10--------
    rs1421501911,2
    --71841022(+) TGAAGA/GTTAAA 3 -- int10--------
    rs1854831091,2
    --71841431(+) TTCTAC/TAAAAC 3 -- int10--------
    rs1512027301,2
    --71841562(+) CAAGAA/GCCAAC 3 -- int10--------
    rs1910293061,2
    --71841568(+) CCAACC/TATATG 3 -- int10--------
    rs1469715511,2
    --71841629(+) TGAGCA/GGATGG 3 -- int10--------
    rs1424135181,2
    C--71841677(+) ACAGAC/TGTAAC 3 -- int10--------
    rs2016258001,2
    --71841829(+) TCTGC-/AAAAAA 3 -- int10--------
    rs1881108471,2
    --71842151(+) CCTAAA/GGGAAG 3 -- int10--------
    rs1447624771,2
    --71842286(+) CCTAAC/TTGATA 3 -- int10--------
    rs1929299271,2
    --71842319(+) AGCTAC/TAGAAT 3 -- int10--------
    rs59588071,2
    C,F,H--71842618(+) ggataC/Tagaaa 3 -- int15Minor allele frequency- T:0.05NS EA WA 418
    rs1827795441,2
    --71842816(+) CAATAC/TAAATG 3 -- int10--------
    rs1872867861,2
    --71842937(+) AAAAGA/GAGATA 3 -- int10--------
    rs1415022421,2
    --71842957(+) GGTAAC/TATAGT 3 -- int10--------
    rs1926335271,2
    --71843502(+) CTTCCA/GAACTC 3 -- int10--------
    rs1383134511,2
    --71843904(+) TTGTAC/GTAATA 3 -- int10--------
    rs1492262711,2
    C--71843938(+) ACACAC/TAGCAA 3 -- int10--------
    rs1846690921,2
    --71844134(+) CTTAAC/TCTTTA 3 -- int10--------
    rs1893560781,2
    --71844163(+) TATATA/CATCCA 3 -- int10--------
    rs59587691,2
    C,F,A,H--71844214(+) GATGGG/ATAGGT 3 -- int118Minor allele frequency- A:0.40NS EA NA WA CSA 1986
    rs1407211001,2
    C--71844340(+) CTTCAT/CAGTAT 6 /M /V mis11Minor allele frequency- C:0.00NA 4530
    rs1446709581,2
    F--71844370(+) AGCTTG/TTTCCT 6 K Q mis11Minor allele frequency- T:0.00NA 4536
    rs126890881,2
    C,F,A,H--71844657(+) TTCCCA/GAAGTC 3 -- int121Minor allele frequency- G:0.39NA EA NS WA CSA 2254
    rs1925229051,2
    --71844746(+) CTAGTC/TAGTAA 3 -- int10--------
    rs1416389541,2
    --71844753(+) GTAACA/GAGAAC 3 -- int10--------
    rs1848386671,2
    C--71844816(+) TAATAA/GAAATA 3 -- int10--------
    rs1512795621,2
    C,F--71844890(+) AGGCCG/AGGAAG 6 /R /W mis11Minor allele frequency- A:0.00NA 4544
    rs1393396611,2
    F--71844898(+) AAGCCT/CGAAAT 6 /Q /R mis11Minor allele frequency- C:0.00NA 4540
    rs1897382071,2
    --71845034(+) CTTCAC/TAGAAC 3 -- int10--------
    rs1811862111,2
    --71845201(+) ATTAAC/TCCACG 3 -- int10--------
    rs1461999651,2
    C--71845243(+) CGACAC/TATAAT 3 -- int10--------
    rs1846692011,2
    --71845398(+) TATTCC/TTAAGA 3 -- int10--------
    rs1890451271,2
    --71845645(+) TGCTGA/GGCTTT 3 -- int10--------
    rs1820874291,2
    --71845656(+) TCCCTA/GTTATA 3 -- int10--------
    rs1872107641,2
    --71845962(+) GTAAAG/TAATGA 3 -- int10--------
    rs70565201,2
    C,F,H--71846130(+) ACCAGT/CTAAAC 3 -- int120Minor allele frequency- C:0.10NS EA NA WA 1930
    rs1416095771,2
    C--71846163(+) AGCATA/GACTAT 3 -- int10--------
    rs1908283871,2
    --71846243(+) ATAAAG/TCAGTG 3 -- int10--------
    rs1505150191,2
    C--71846289(+) TGCCCA/GCCCCT 3 -- int10--------
    rs2012340131,2
    C--71846425(+) GGAACC/TGATCT 5 Q R mis1 int10--------
    rs1396102871,2
    --71846779(+) CTTGAA/GAGCAG 3 -- int10--------
    rs735003441,2
    C,F--71846804(+) ACATTG/AGAGCA 3 -- int11Minor allele frequency- A:0.50WA 2
    rs1864448511,2
    --71846837(+) TGTGTA/GTGTGC 3 -- int10--------
    rs1915276081,2
    --71846846(+) GCATGG/TGATAG 3 -- int10--------
    rs1824683761,2
    --71847008(+) CCAGGC/TAGTGT 3 -- int10--------
    rs1875098491,2
    --71847043(+) GAAGAA/GGATGG 3 -- int10--------
    rs173121711,2
    C,F--71847118(+) ATGGGC/TAATGG 3 -- int13--NA 142
    rs1904828591,2
    --71847150(+) CTGTGA/GAAGCT 3 -- int10--------
    rs66246211,2
    C,F,A,H--71847205(+) GAAAAA/GCACAC 3 -- int120Minor allele frequency- G:0.74NS EA NA WA CSA 2044
    rs1832443451,2
    --71847206(+) AAAAAC/TACACT 3 -- int10--------
    rs1397124301,2
    --71847220(+) CAGATA/CGATAC 3 -- int10--------
    rs1452379861,2
    --71847279(+) ACTGAG/TCTCTC 3 -- int10--------
    rs1888915711,2
    --71847319(+) AATGCA/GAACTA 3 -- int10--------
    rs1478945521,2
    --71847462(+) TGGCAA/GGCAAT 3 -- int10--------
    rs1924077121,2
    --71847619(+) CAACTA/TCCCAT 3 -- int10--------
    rs1845926701,2
    --71847827(+) ATGTCA/GGGCCC 3 -- int10--------
    rs1875523431,2
    --71847852(+) TCCTTC/TTGACT 3 -- int10--------
    rs1416696661,2
    --71847945(+) ATACCA/GCTCTT 3 -- int10--------
    rs1919184391,2
    --71848249(+) TACTAC/TGAAAA 3 -- int10--------
    rs1427751311,2
    --71848523(+) GGACTC/GTCCAA 3 -- int10--------
    rs1841632331,2
    --71848586(+) TAGAGG/TGAGGA 3 -- int10--------
    rs1890909181,2
    C--71848708(+) AGCCAA/GGCCAG 3 -- int10--------
    rs1510462071,2
    --71848968(+) TCTTAC/GTGATA 3 -- int10--------
    rs1814800521,2
    --71849613(+) CACAGA/TATGAT 3 -- int10--------
    rs1856246291,2
    --71849741(+) CCAGGC/TTGAAC 3 -- int10--------
    rs1905113601,2
    --71849829(+) TGAAAA/GAGACT 3 -- int10--------
    rs1819971461,2
    --71849905(+) TACCAC/GAAGCA 3 -- int10--------
    rs59121101,2
    C,F,H--71849954(+) ccctcA/Ggttcc 3 -- int14Minor allele frequency- G:0.01NS EA 416
    rs586541031,2
    C--71850090(+) CAATAC/TGCCAC 3 -- int10--------
    rs186213876