Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



PHF21B Gene

protein-coding   GIFtS: 50
GCID: GC22M045277

PHD Finger Protein 21B

(Previous name: PHD finger protein 4)
(Previous symbol: PHF4)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
PHD Finger Protein 21B1 2
PHF41 2
PHD Finger Protein 41 2
BHC80L2
KIAA16613

External Ids:    HGNC: 251611   Entrez Gene: 1128852   Ensembl: ENSG000000564877   UniProtKB: Q96EK23   

Export aliases for PHF21B gene to outside databases

Previous GC identifers: GC22M043598 GC22M028224


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for PHF21B Gene:
PHF21B (PHD finger protein 21B) is a protein-coding gene. Diseases associated with PHF21B include endotheliitis. An important paralog of this gene is PHF21A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000022.11  NT_011520.13  NC_018933.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PHF21B gene promoter:
         Max1   SRF   S8   p53   SRF (504 AA)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPHF21B promoter sequence
   Search Chromatin IP Primers for PHF21B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PHF21B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.31   Ensembl cytogenetic band:  22q13.31   HGNC cytogenetic band: 22q13.31

PHF21B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PHF21B gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M045277:  view genomic region     (about GC identifiers)

Start:
45,277,042 bp from pter      End:
45,405,880 bp from pter
Size:
128,839 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: PF21B_HUMAN, Q96EK2 (See protein sequence)
Recommended Name: PHD finger protein 21B  
Size: 531 amino acids; 57455 Da
Secondary accessions: B0QYW3 B0QYW4 B3KRU4 B7Z4F8 Q5TFL2 Q6ICC0
Alternative splicing: 3 isoforms:  Q96EK2-1   Q96EK2-3   Q96EK2-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PHF21B: NX_Q96EK2

Explore proteomics data for PHF21B at MOPED


See PHF21B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (4 alternative transcripts): 
NP_001129334.1  NP_001229379.1  NP_001271225.1  NP_612424.1  

ENSEMBL proteins: 
 ENSP00000385053   ENSP00000324403   ENSP00000401091   ENSP00000401294   ENSP00000379410  
 ENSP00000385105   ENSP00000388619  

PHF21B Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for PHF21B
OriGene Custom MassSpec
OriGene Custom Protein Services for PHF21B
GenScript Custom Purified and Recombinant Proteins Services for PHF21B
Novus Biologicals PHF21B Protein
Novus Biologicals PHF21B Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for PHF21B

PHF21B Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
OriGene Antibodies for PHF21B
OriGene Custom Antibody Services for PHF21B
Novus Biologicals PHF21B Antibodies
Abcam antibodies for PHF21B
Cloud-Clone Corp. Antibodies for PHF21B
ThermoFisher Antibodies for PHF21B
LSBio Antibodies in human, mouse, rat for PHF21B

PHF21B Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for PHF21B
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for PHF21B
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for PHF21B
Cloud-Clone Corp. CLIAs for PHF21B


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
HGNC Gene Families:
PHF: Zinc fingers, PHD-type

4 InterPro protein domains:
 IPR001965 Znf_PHD
 IPR013083 Znf_RING/FYVE/PHD
 IPR011011 Znf_FYVE_PHD
 IPR019787 Znf_PHD-finger

Graphical View of Domain Structure for InterPro Entry Q96EK2

ProtoNet protein and cluster: Q96EK2

1 Blocks protein domain: IPB001965 Zn-finger-like

UniProtKB/Swiss-Prot: PF21B_HUMAN, Q96EK2
Similarity: Contains 1 PHD-type zinc finger


PHF21B for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding ----
GO:0008270zinc ion binding IEA--
     
PHF21B for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for PHF21B:
 Synthetic lethal with Ras 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PHF21B
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PHF21B

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PHF21B
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PHF21B

miRNA
Products:
    
miRTarBase miRNAs that target PHF21B:
hsa-mir-124-3p (MIRT022492)

Block miRNA regulation of human, mouse, rat PHF21B using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate PHF21B (see all 37):
hsa-miR-429 hsa-miR-629* hsa-miR-3658 hsa-miR-208a hsa-miR-208b hsa-miR-186 hsa-miR-23a hsa-miR-200b
SwitchGear 3'UTR luciferase reporter plasmidPHF21B 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for PHF21B
Predesigned siRNA for gene silencing in human, mouse, rat PHF21B

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for PHF21B

Clone
Products:
     
OriGene clones in human, mouse for PHF21B (see all 11)
OriGene ORF clones in mouse, rat for PHF21B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): PHF21B (NM_138415)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for PHF21B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF21B

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for PHF21B
Browse ESI BIO Cell Lines and PureStem Progenitors for PHF21B 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF21B


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus3
cytosol2

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus



    Pathway & Disease-focused RT2 Profiler PCR Array including PHF21B: 
          Epigenetic Chromatin Remodeling Factors in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for PHF21B

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for PHF21B (ENSP000003244034) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
RRP12ENSP000003600314STRING: ENSP00000360031
NAT10ENSP000002578294STRING: ENSP00000257829
SRP72ENSP000003421814STRING: ENSP00000342181
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for PHF21B (PF21B)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for PHF21B gene (4 alternative transcripts): 
NM_001135862.2  NM_001242450.1  NM_001284296.1  NM_138415.4  

Unigene Cluster for PHF21B:

PHD finger protein 21B
Hs.254097  [show with all ESTs]
Unigene Representative Sequence: BC012187
13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000403565(uc011aqk.2 uc003bfm.3 uc011aqm.1) ENST00000313237(uc003bfn.3 uc011aql.2)
ENST00000414269 ENST00000420689 ENST00000490679 ENST00000460507 ENST00000474327
ENST00000462631 ENST00000495348 ENST00000491522 ENST00000396103 ENST00000404079
ENST00000447824
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat PHF21B using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate PHF21B (see all 37):
hsa-miR-429 hsa-miR-629* hsa-miR-3658 hsa-miR-208a hsa-miR-208b hsa-miR-186 hsa-miR-23a hsa-miR-200b
SwitchGear 3'UTR luciferase reporter plasmidPHF21B 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for PHF21B
Predesigned siRNA for gene silencing in human, mouse, rat PHF21B
Clone
Products:
     
OriGene clones in human, mouse for PHF21B (see all 11)
OriGene ORF clones in mouse, rat for PHF21B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): PHF21B (NM_138415)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for PHF21B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF21B
Primer
Products:
    
OriGene qPCR primer pairs and template standards for PHF21B
OriGene qSTAR qPCR primer pairs in human, mouse for PHF21B
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PHF21B
  QuantiTect SYBR Green Assays in human, mouse, rat PHF21B
  QuantiFast Probe-based Assays in human, mouse, rat PHF21B

Additional mRNA sequence: 

AK091480.1 AK092243.1 AK095777.1 AK297317.1 AK299836.1 BC012187.1 CR456448.1 

5 DOTS entries:

DT.100811425  DT.100021797  DT.426098  DT.95295776  DT.100028517 

Selected AceView cDNA sequences (see all 83):

AA832493 CR456448 NM_138415 AW246869 AI571636 AW250723 BX090864 BE254267 
BU584659 CR615765 BU585295 BM724591 AA826425 BC012187 BE256338 BU585310 
BU584847 BU585300 BU585312 BU585306 BU585331 AK091480 BU585284 BU585309 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for PHF21B (see all 9)    About this scheme

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
SP1:                    -           -     -     -     -     -     -     -     -     -                                                                           
SP2:                    -           -     -     -     -     -     -     -     -     -                             -                                             
SP3:                                -     -     -     -     -     -     -     -                                   -                                             
SP4:                                -     -     -     -     -     -     -     -     -                                                                           
SP5:                    -           -     -     -     -     -                                                                                                   

ExUns: 21 ^ 22
SP1:            
SP2:            
SP3:            
SP4:            
SP5:            


ECgene alternative splicing isoforms for PHF21B

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

PHF21B expression in normal human tissues (normalized intensities)      PHF21B embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTTTAACAGT
PHF21B Expression
About this image


PHF21B expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 4) fully expand
 
 Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
         Human embryonic stem cells (family)
 
 Endothelium (Cardiovascular System)
         Mature Endothelial Cells Blood Brain Barrier
 
 Brain (Nervous System)
         Mature Endothelial Cells Blood Brain Barrier
 
 Eye (Sensory Organs)
PHF21B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

PHF21B Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.254097
    Pathway & Disease-focused RT2 Profiler PCR Array including PHF21B: 
          Epigenetic Chromatin Remodeling Factors in human mouse rat

Primer
Products:
OriGene qPCR primer pairs and template standards for PHF21B
OriGene qSTAR qPCR primer pairs in human, mouse for PHF21B
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PHF21B
QuantiTect SYBR Green Assays in human, mouse, rat PHF21B
QuantiFast Probe-based Assays in human, mouse, rat PHF21B
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF21B

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of animals and fungi.

Orthologs for PHF21B gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Phf21b1 , 5 PHD finger protein 21B1, 5 88.2(n)1
88.68(a)1
  15 (40.08 cM)5
2713051  NM_001081166.21  NP_001074635.21 
 847853815 
chicken
(Gallus gallus)
Aves PHF21B1 PHD finger protein 21B 76.88(n)
78.88(a)
  427935  XM_004938038.1  XP_004938095.1 
lizard
(Anolis carolinensis)
Reptilia PHF21B6
PHD finger protein 21B
74(a)
1 ↔ 1
5(84870594-84925283)
African clawed frog
(Xenopus laevis)
Amphibia Xl.126932 Xenopus laevis transcribed sequences 81.6(n)    BJ089571.1 
zebrafish
(Danio rerio)
Actinopterygii PHF21B (2 of 2)6
CABZ01111990.16
Uncharacterized protein
53(a)
47(a)
many → 1
many → 1
4(60130116-60141981) ENSDARG00000087887
4(60116387-60125559) ENSDARG00000087105
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RCO16
Essential subunit of the histone deacetylase Rpd3S...
7(a)
1 → many
XIII(413982-416036) YMR075W


ENSEMBL Gene Tree for PHF21B (if available)
TreeFam Gene Tree for PHF21B (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
Paralogs for PHF21B gene
PHF21A2  
1 SIMAP similar gene for PHF21B using alignment to 5 protein entries:     PF21B_HUMAN (see all proteins):
AIRE

PHF21B for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for PHF21B (see all 3894)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 22 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1844037501,2
--28351757(+) TTCCGA/CTGGGA 1 -- int10--------
rs121694011,2
C,F,A--28352013(+) CGATTA/GAACTC 1 -- int16Minor allele frequency- G:0.07NA CSA WA 246
rs60074101,2
C,F,A--28352087(+) CGACCT/CAAAAC 1 -- int1 tfbs36Minor allele frequency- C:0.06NA CSA WA 246
rs1405521,2
C,F--28352107(+) TACAGC/TTGCGG 1 -- int14Minor allele frequency- T:0.17MN WA NA EA 542
rs1443760151,2
--28352155(+) GGTTAA/GTGTCC 1 -- int10--------
rs1860980661,2
--28352591(+) GAGCAA/CGACAG 2 -- int1 us2k10--------
rs57662831,2
C,F--28352615(+) ATATGA/GGTAAC 2 -- int1 us2k1 tfbs32Minor allele frequency- G:0.08WA NA 238
rs119131881,2
C,H--28352727(+) gggggC/Tggtgg 2 -- int1 us2k10--------
rs110907191,2
C,F,A,H--28352729(+) gggcgG/Atggct 2 -- int1 us2k13Minor allele frequency- A:0.09NA CSA 123
rs1319911,2
C,F,H--28353076(+) GAAGAC/TGACCT 1 -- int133Minor allele frequency- T:0.26NS EA NA WA CSA 2989

HapMap Linkage Disequilibrium report for PHF21B (45277042 - 45405880 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for PHF21B (see all 28):    About this table    
Variant IDTypeSubtypePubMed ID
esv1527783CNV Deletion17803354
esv2661257CNV Deletion23128226
esv1949381CNV Deletion18987734
esv2724382CNV Deletion23290073
esv2724379CNV Deletion23290073
esv2724375CNV Deletion23290073
esv2457019CNV Deletion19546169
esv2724385CNV Deletion23290073
esv2724381CNV Deletion23290073
esv2724378CNV Deletion23290073

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing PHF21B
DNA2.0 Custom Variant and Variant Library Synthesis for PHF21B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
1 disease for PHF21B:    About MalaCards
endotheliitis


PHF21B for disorders           About GeneDecksing

Genetic Association Database (GAD): PHF21B
Human Genome Epidemiology (HuGE) Navigator: PHF21B (1 document)

Export disorders for PHF21B gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for PHF21B gene integrated from 10 sources:
(articles sorted by number of sources associating them with PHF21B)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
  2. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  6. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
  7. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 112885 HGNC: 25161 AceView: LOC112885 Ensembl:ENSG00000056487 euGenes: HUgn112885
ECgene: PHF21B H-InvDB: PHF21B

(According to HUGE)
About This Section

TryGeneCards Plus
HUGE: KIAA1661

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for PHF21B Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for PHF21B gene:
Search GeneIP for patents involving PHF21B

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 OriGene Antibodies for PHF21B   OriGene RNAi products in human, mouse, rat for PHF21B  
 OriGene qPCR primer pairs and template standards for PHF21B   OriGene Protein Over-expression Lysate for PHF21B  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for PHF21B  
 OriGene qSTAR qPCR primer pairs in human, mouse for PHF21B   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for PHF21B   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for PHF21B   OriGene Custom Protein Services for PHF21B  

 
 
 Block miRNA regulation of human, mouse, rat PHF21B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PHF21B
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PHF21B Predesigned siRNA for gene silencing in human, mouse, rat PHF21B
 QuantiFast Probe-based Assays in human, mouse, rat PHF21B QuantiTect SYBR Green Assays in human, mouse, rat PHF21B
 PCR Arrays including human, mouse, rat PHF21B Search Chromatin IP Primers for PHF21B
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PHF21B  Search GeneGlobe Interaction Network for PHF21B
 Regulatory tfbs in PHF21B promoter
 GenScript Custom Purified and Recombinant Proteins Services for PHF21B GenScript cDNA clones with any tag delivered in your preferred vector for PHF21B
 GenScript Custom Assay Services for PHF21B GenScript Custom overexpressing Cell Line Services for PHF21B
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for PHF21B (PF21B)
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 PHF21B antibodies
 PHF21B proteins
 PHF21B lysates
 Antibodies for PHF21B
 See all of Abcam's Antibodies, Kits and Proteins for PHF21B
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for PHF21B
 Antibodies for PHF21B
 ELISAs for PHF21B
 CLIAs for PHF21B



 Browse ESI BIO Cell Lines and PureStem Progenitors for PHF21B
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF21B
 SwitchGear 3'UTR luciferase reporter plasmids for PHF21B
 SwitchGear Promoter luciferase reporter plasmids for PHF21B
 ThermoFisher Antibodies for PHF21B
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF21B
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PHF21B
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PHF21B
 LSBio Antibodies in human, mouse, rat for PHF21B
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      PHF21B gene at Home site.
Version: 3.12.136 22 July 2014
hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4