PHF21A Gene
protein-coding GIFtS: 55
GCID: GC11M045950
|
|
PHD finger protein 21A
| |
Aliases
for PHF21A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| PHD Finger Protein 21A1 2 | | BRAF35-HDAC Complex Protein BHC802 3 | | BHC801 2 3 5 | | BM-0061 | | KIAA16961 3 5 | | BRAF35/HDAC2 Complex (80 KDa)2 | | BHC80a2 3 | | |
Export aliases for PHF21A gene to outside databasesPrevious GC identifers: GC11M045911 GC11M045657 |
Summaries
for PHF21A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PHF21A:
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex(BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressorelement-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 (PubMed 12032298)).(supplied by OMIM, Nov2010)
UniProtKB/Swiss-Prot: PF21A_HUMAN, Q96BD5Function: Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes innon-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylatingspecific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold.Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation
Gene Wiki entry for PHF21A
|
Genomic Views
for PHF21A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PHF21A gene promoter:
HOXA9B HOXA9 LCR-F1 C/EBPalpha CHOP-10 MZF-1 FOXO1a Meis-1a FOXO1 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PHF21A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHF21A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p11.2 Ensembl cytogenetic band: 11p11.2 HGNC cytogenetic band: 11p11.2PHF21A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M045950: view genomic region
(about GC identifiers)
Start:
|
45,950,870 bp from pter |
End:
|
46,142,985 bp from pter |
Size:
|
192,116 bases |
Orientation:
|
minus strand |
|
Proteins
for PHF21A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PF21A_HUMAN, Q96BD5 (See
protein sequence)Recommended Name: PHD finger protein 21A Size: 680 amino acids; 74854 Da
Subunit: Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoRESTand PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. In the complex, it interactsdirectly with HDAC1, HDAC2, HMG20B/BRAF35, KDM1A and RCOR1/CoREST
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=AAF64262.1; Type=Frameshift; Positions=Several; Sequence=BAB21787.1; Type=Erroneousinitiation;
2 PDB 3D structures from  and Proteopedia  for PHF21A:2PUY (3D)
2YQL (3D)
Secondary accessions: D3DQP5 Q6AWA2 Q9C0G7 Q9H8V9 Q9HAK6 Q9NZE9Alternative splicing: 3 isoforms: Q96BD5-1 Q96BD5-2 Q96BD5-3 Explore the universe of human proteins at neXtProt for PHF21A: NX_Q96BD5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96BD5
PHF21A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001095272.1 NP_057705.3
ENSEMBL proteins: ENSP00000323152 ENSP00000435984 ENSP00000398824 ENSP00000431964 ENSP00000431621 ENSP00000432094 ENSP00000431273 ENSP00000432916 ENSP00000436157 ENSP00000435121 ENSP00000432406 ENSP00000437110 ENSP00000434687 ENSP00000435645 ENSP00000257821 Reactome Protein details: Q96BD5
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
PHF21A for ontologies About GeneDecksing
PHF21A Antibody Products:
Assay Products for PHF21A: |
Protein
Domains /
Families
for PHF21A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PHF21A for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q96BD5ProtoNet protein and cluster: Q96BD5 1 Blocks protein family: IPB001841 Zn-finger
UniProtKB/Swiss-Prot: PF21A_HUMAN, Q96BD5Similarity: Contains 1 A.T hook DNA-binding domainSimilarity: Contains 1 PHD-type zinc finger |
Function
for PHF21A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PF21A_HUMAN, Q96BD5Function: Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes innon-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylatingspecific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold.Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHF21A (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHF21A (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): PHF21A (NM_016621) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PHF21A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF21A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF21A |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
PHF21A for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for PHF21A:
Animal Models:
Mouse knock-out Phf21atm1Tba for PHF21A
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Phf21a):
PHF21A for phenotypes About GeneDecksing
|
Pathways & Interactions
for PHF21A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Factors involved in megakaryocyte development and platelet production | | | 2 | Platelet activation, signaling and aggregation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for PHF21A
PHF21A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PHF21A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/54 Interacting proteins for PHF21A (Q96BD52, 3 ENSP000003988244) via UniProtKB, MINT, STRING, and/or I2D (see all 54)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IDA | 15325272 | | GO:0001967 | suckling behavior |
IEA | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0007596 | blood coagulation |
TAS | -- |
PHF21A for ontologies About GeneDecksing
|
Drugs & Compounds
for PHF21A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PHF21A
Search CenterWatch for drugs/clinical trials and news about PHF21A / PF21A
|
Transcripts
for PHF21A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PHF21A gene (2 alternative transcripts): NM_001101802.1 NM_016621.3 Unigene Cluster for PHF21A: PHD finger protein 21A Hs.502458 [show with all ESTs]Unigene Representative Sequence: NM_00110180218/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000527401(uc001nca.1) ENST00000323180 ENST00000530587 ENST00000418153
ENST00000525676 ENST00000532028 ENST00000534724 ENST00000527753 ENST00000534766
ENST00000532883 ENST00000525679 ENST00000524497 ENST00000531959 ENST00000529734
ENST00000529782 ENST00000533757 ENST00000525438 ENST00000527782
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHF21A (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHF21A (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): PHF21A (NM_016621) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PHF21A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF21A |
Additional cDNA sequence: AB051483.1 AF208848.1 AK021530.1 AK023258.1 AL359593.1 AL359608.1 AL832258.1 AY090777.1 BC015714.2 20 DOTS entries: DT.212580 DT.100780643 DT.453970 DT.95168886 DT.100780646 DT.92021628 DT.91886002 DT.100780647 DT.120759297 DT.120759302 DT.91749098 DT.95135258 DT.100650284 DT.106867 DT.120759191 DT.120759237 DT.120759315 DT.70103250 DT.100658944 DT.312600 24/274 AceView cDNA sequences (see all 274): AL832258 Z42786 AI384081 AI279824 N78722 BE217989 AI080592 F03916 BG055418 AW292630 BE218518 AA808905 AK023258 BE220226 AA485181 AA721452 AI554269 BU076399 CA390555 AI825211 CR624589 AA905840 BE042993 BU737790
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for PHF21A (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | - | | | | - | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | - | | | | - | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP4: | | | | | | | - | | - | | - | | - | | | | - | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP5: | | | | | | | | | | | | | - | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | · | 26c |
|---|
|
| SP1: | - | | - | | | | | | | | | | | | | | |
| SP2: | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PHF21A
|
Expression
for PHF21A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PHF21A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See PHF21A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PHF21A
SOURCE GeneReport for Unigene cluster: Hs.502458
UniProtKB/Swiss-Prot: PF21A_HUMAN, Q96BD5Tissue specificity: Highly expressed in brain. Expressed at much lower level in other tissues
SABiosciences Expression via Pathway-Focused PCR Array including PHF21A: | Epigenetic Chromatin Remodeling Factors in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PHF21A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat PHF21A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHF21A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHF21A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF21A |
Orthologs
for PHF21A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for PHF21A gene from 3/15 species (see all 15) About this table
ENSEMBL Gene Tree for PHF21A (if available)
TreeFam Gene Tree for PHF21A (if available) |
Paralogs
for PHF21A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PHF21A gene
- PHF21B2
4 SIMAP similar genes for PHF21A using alignment to 11 protein entries: PF21A_HUMAN (see all proteins):PHRF1 CHD4 KDM5A PHF12
PHF21A for paralogs About GeneDecksing
|
Genomic Variants
for PHF21A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PHF21A (45950870 - 46142985 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for PHF21A
3 CNVs: 5625 48808 101208
3 Indels: 61131 71319 42460
Human Gene Mutation Database (HGMD): PHF21A
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PHF21A |
|
Disorders
/ Diseases
for PHF21A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PHF21A for disorders About GeneDecksing
OMIM gene information: 608325
OMIM disorders: --
1  disease for PHF21A: About MalaCardsneuronitis
Human Genome Epidemiology (HuGE) Navigator: PHF21A (1 document)
Export disorders for PHF21A gene to outside databases
|
Publications
for PHF21A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PHF21A gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with PHF21A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes. (PubMed id 12032298)1, 2, 3 Hakimi M.A....Shiekhattar R. (2002)
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (2000)
- Regulation of LSD1 histone demethylase activity by its associated factors. (PubMed id 16140033)1, 2 Shi Y.-J.... Shi Y. (2005)
- Characterization of BHC80 in BRAF-HDAC complex, involved in neuron- specific gene repression. (PubMed id 15325272)1, 2 Iwase S....Baba T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes. (PubMed id 12493763)1, 2 Hakimi M.A....Shiekhattar R. (2003)
- The rest repression of the neurosecretory phenotype is negatively modulated by BHC80, a protein of the BRAF/HDAC complex. (PubMed id 19439607)1, 9 Klajn A....D'Alessandro R. (2009)
- Esco2 is a novel corepressor that associates with various chromatin modifying enzymes. (PubMed id 18501190)1, 9 Kim B.J....Kim S.T. (2008)
- Translocations disrupting PHF21A in the Potocki-Shaffe r-syndrome region are associated with intellectual disability and craniofacial a nomalies. (PubMed id 22770980)1 Kim H.G....Gusella J.F. (2012)
|
External Searches for PHF21A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PHF21A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PHF21A gene
(According to HUGE)
About This Section
| |
Specialized Databases showing PHF21A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PHF21A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PHF21A gene:
Search GeneIP for patents involving PHF21A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PHF21A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PHF21A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PHF21A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PHF21A | | | OriGene Protein Over-expression Lysate for PHF21A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PHF21A | | OriGene 3'-UTR Clone for PHF21A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHF21A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHF21A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PHF21A | | OriGene Custom Protein Services for PHF21A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PHF21A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PHF21A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHF21A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PHF21A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHF21A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHF21A |
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| | | | Search Tocris compounds for PHF21A |
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 | | | PHF21A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF21A |
|  |  |  | | | | Search ThermoFisher Antibodies for PHF21A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF21A |
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