PHF20 Gene
protein-coding GIFtS: 55
GCID: GC20P034359
|
|
PHD finger protein 20(Previous name: chromosome 20 open reading frame 104 ) (Previous symbol: C20orf104)
| |
Aliases for PHF20 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| PHD Finger Protein 201 2 | | GLEA22 3 | | C20orf1041 2 3 | | HCA582 3 | | TDRD20A1 2 | | NZF2 3 | | Glioma-Expressed Antigen 22 3 | | TZP2 3 | | Hepatocellular Carcinoma-Associated Antigen 582 3 | | Chromosome 20 Open Reading Frame 1041 | | Novel Zinc Finger Protein2 3 | | DJ1121G12.11 | | Transcription Factor TZP2 3 | | Tudor Domain Containing 20A2 |
Export aliases for PHF20 gene to outside databasesPrevious GC identifers: GC20P033824 GC20P031137 |
Summaries for PHF20 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: PHF20_HUMAN, Q9BVI0Function: Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not requiredfor maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, butinstead works downstream in transcriptional regulation of MOF target genes (By similarity). As part of the NSL complexit may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes tomethyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage Gene Wiki entry for PHF20
|
Genomic Views for PHF20 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the PHF20 gene promoter: Egr-3 HOXA9 HOXA9B Pbx1a Egr-4 Meis-1b Egr-2 Pax-4a ATF6 Meis-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for PHF20
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHF20 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q11.22-q11.23 Ensembl cytogenetic band: 20q11.22 HGNC cytogenetic band: 20q11.22-q11.23PHF20 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P034359: view genomic region
(about GC identifiers)
Start:
|
34,359,896 bp from pter |
End:
|
34,538,303 bp from pter |
Size:
|
178,408 bases |
Orientation:
|
plus strand |
|
Proteins for PHF20 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: PHF20_HUMAN, Q9BVI0 (See
protein sequence)Recommended Name: PHD finger protein 20 Size: 1012 amino acids; 115386 Da
Subunit: Homodimer; disulfide-linked. Component of some MLL1/MLL complex, at least composed of the core components MLL,ASH2L, HCFC1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L,MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9and TEX10. Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT,WDR5 and HCFC1
Subcellular location: Nucleus
Miscellaneous: Antibodies against PHF20 are present in sera from patients with hepatocellular carcinoma, glioblastomaand childhood medulloblastula
Sequence caution: Sequence=AAF34184.1; Type=Frameshift; Positions=260; Sequence=AAK19748.1; Type=Frameshift;Positions=635, 653, 655;
5 PDB 3D structures from and Proteopedia for PHF20:2LDM (3D)
  3P8D (3D)
  3Q1J (3D)
  3QII (3D)
  3SD4 (3D)
 
Secondary accessions: A7E235 B2RB56 E1P5S3 Q566Q2 Q5JWY9 Q66K49 Q9BWV4 Q9BXA3 Q9BZW3 Q9H421 Q9H4J6Q9NZ22Alternative splicing: 2 isoforms: Q9BVI0-1 Q9BVI0-2 (Ref.1 (AAF34184) sequence is in conflict in positions: 237:KTR->KKTS)Explore the universe of human proteins at neXtProt for PHF20: NX_Q9BVI0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BVI0 PHF20 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057520.2 ENSEMBL proteins: ENSP00000363124 ENSP00000404455 ENSP00000341900 ENSP00000363112 ENSP00000391915 ENSP00000413712 ENSP00000410373 Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
PHF20 for ontologies About GeneDecksing
PHF20 Antibody Products: Assay Products for PHF20: |
Protein
Domains / Families for PHF20 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PHF20 for domains About GeneDecksing
5/10 InterPro domains/families (see all 10):Graphical View of Domain Structure for InterPro Entry Q9BVI0ProtoNet protein and cluster: Q9BVI0 2 Blocks protein families: IPB001965 Zn-finger-like IPB002999 Tudor domain
UniProtKB/Swiss-Prot: PHF20_HUMAN, Q9BVI0Domain: The Tudor domain 2 mediates reading of dimethyl-lysine residuesDomain: The Tudor domain 1 doesn't bind dimethyl-lysine residues, due to an atypical and occluded aromatic cageSimilarity: Contains 1 A.T hook DNA-binding domainSimilarity: Contains 1 C2H2-type zinc fingerSimilarity: Contains 1 PHD-type zinc fingerSimilarity: Contains 2 Tudor domains |
Function for PHF20 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: PHF20_HUMAN, Q9BVI0Function: Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not requiredfor maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, butinstead works downstream in transcriptional regulation of MOF target genes (By similarity). As part of the NSL complexit may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes tomethyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHF20 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHF20 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): PHF20 (NM_016018) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PHF20 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF20  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF20 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- | | GO:0043995 | contributes to histone acetyltransferase activity (H4-K5 specific) |
IDA | -- | | GO:0043996 | contributes to histone acetyltransferase activity (H4-K8 specific) |
IDA | -- | | GO:0046972 | contributes to histone acetyltransferase activity (H4-K16 specific) |
IDA | -- |
PHF20 for ontologies About GeneDecksing
6 GenomeRNAi human phenotypes for PHF20: Animal Models: 7 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Phf20):
PHF20 for phenotypes About GeneDecksing
|
Pathways & Interactions for PHF20 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Cell Signaling Technology (CST) Pathway for PHF20
PHF20 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PHF20
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/54 Interacting proteins for PHF20 (Q9BVI02, 3 ENSP000003631244) via UniProtKB, MINT, STRING, and/or I2D (see all 54)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0043981 | histone H4-K5 acetylation |
IDA | -- | | GO:0043982 | histone H4-K8 acetylation |
IDA | -- | | GO:0043984 | histone H4-K16 acetylation |
IDA | -- |
PHF20 for ontologies About GeneDecksing
|
Drugs & Compounds for PHF20 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for PHF20 Search CenterWatch for drugs/clinical trials and news about PHF20 
|
Transcripts for PHF20 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for PHF20 gene: NM_016436.4 Unigene Cluster for PHF20: PHD finger protein 20 Hs.517044 [show with all ESTs]Unigene Representative Sequence: BC15017816 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000461122 ENST00000374012(uc002xej.1 uc002xek.1) ENST00000461405 ENST00000452270 ENST00000339089(uc002xei.1) ENST00000374000(uc002xel.1 uc010gfo.1) ENST00000481202 ENST00000449988 ENST00000486408 ENST00000495338 ENST00000496305 ENST00000480940 ENST00000485604 ENST00000420233 ENST00000473943 ENST00000439301(uc002xeh.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHF20 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHF20 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): PHF20 (NM_016018) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PHF20 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF20  |
Additional cDNA sequence: AF220416.1 AF258787.1 AF348207.1 AK054597.1 AK090798.1 AK097498.1 AK314503.1 AL137330.1 AY027523.1 AY134747.1 BC006415.1 BC015538.2 BC016948.1 BC022933.1 BC048210.1 BC062681.1 BC080598.1 BC093405.1 BC150178.1 22 DOTS entries: DT.100044409 DT.305771 DT.95154061 DT.100780272 DT.92472013 DT.101985494 DT.443943 DT.443988 DT.92472026 DT.100042229 DT.100725372 DT.92472059 DT.100774767 DT.91796016 DT.92472043 DT.120825619 DT.75147899 DT.75148089 DT.95329770 DT.102831124 DT.120825578 DT.120825622 24/204 AceView cDNA sequences (see all 204): BQ436139 Z43217 C21160 BQ028521 CA432348 CB139717 AY134747 AA599532 BF970213 BC048210 AK097498 AI081823 BM562675 BU742208 AU119982 AL137330 BC015538 AL040922 AI992137 AL558423 BQ642597 AI926894 CA442864 CR626103 GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for PHF20 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |
| SP2: | |   | |   | |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 20b | ^ | 21a | · | 21b | ^ | 22 | |
| SP1: | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   |
ECgene alternative splicing isoforms for PHF20
|
Expression for PHF20 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PHF20 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTGAGGGGCT
About this image See PHF20 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for PHF20
SOURCE GeneReport for Unigene cluster: Hs.517044 UniProtKB/Swiss-Prot: PHF20_HUMAN, Q9BVI0Tissue specificity: Expressed in heart, kidney, liver, lung, pancreas, placenta, spleen and testis. Not expressed inbrain, skeletal muscle, colon, ovary, prostate, small intestine and thymus. Expressed in colon and ovary cancer celllines while it is not expressed in the respective normal tissues SABiosciences Custom PCR Arrays for PHF20
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PHF20 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PHF20 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHF20 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHF20 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF20 |
Orthologs for PHF20 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PHF20 gene from 5/19 species (see all 19) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
PHF201 |
PHD finger protein 20 |
70.03(n) 66.47(a) |
  |
419131 XM_003642447.1 XP_003642495.1 |
lizard (Anolis carolinensis) |
Reptilia |
PHF206 |
-- |
66(a) |
1 ↔ 1 |
4(134639745-134673562) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.177572 |
Xenopus laevis transcribed sequence with moderate similarity more |
78.9(n) |
  |
BG814107.1 |
zebrafish (Danio rerio) |
Actinopterygii |
phf20b1 |
PHD finger protein 20, b |
54.57(n) 47.52(a) |
  |
445482 NM_001004114.1 NP_001004114.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
MBD-R26 |
MBD-R2 |
13(a) |
1 → many |
3R(8177865-8182024) |
ENSEMBL Gene Tree for PHF20 (if available) TreeFam Gene Tree for PHF20 (if available)  |
Paralogs for PHF20 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for PHF20 gene
- PHF20L12
1 SIMAP similar gene for PHF20 using alignment to 6 protein entries: PHF20_HUMAN (see all proteins):PHF20L1
PHF20 for paralogs About GeneDecksing
|
Genomic Variants for PHF20 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 20 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for PHF20 (34359896 - 34538303 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for PHF20 1 CNV: 5135  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PHF20 |
|
Disorders
/ Diseases for PHF20 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PHF20 for disorders About GeneDecksing
OMIM gene information: 610335
OMIM disorders: --
10 diseases for PHF20: About MalaCardshepatocellular carcinoma carcinoma childhood medulloblastoma gastroparesis ileus medulloblastoma prostatic hypertrophy lung cancer glioblastoma prostatitis 3 diseases from the University of Copenhagen DISEASES database for PHF20:Gastroparesis Large cell medulloblastoma Ileus Export disorders for PHF20 gene to outside databases
|
Publications for PHF20 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PHF20 gene, integrated from 9 sources (see all 27): (articles sorted by number of sources associating them with PHF20) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Glioma-expressed antigen 2 (GLEA2): a novel protein that can elicit immune responses in glioblastoma patients and some controls. (PubMed id 11703362)1, 2, 9 Fischer U....Meese E. (2001)
- Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries. (PubMed id 12800201)1, 2, 9 Behrends U.... Mautner J. (2003)
- PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. (PubMed id 22864287)1, 2 Cui G.... Mer G. (2012)
- Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins. (PubMed id 22449972)1, 2 Adams-Cioaba M.A....Min J. (2012)
- Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Large scale identification of human hepatocellular carcinoma- associated antigens by autoantibodies. (PubMed id 12097419)1, 2 Wang Y....Chen W.-F. (2002)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
|
External Searches for PHF20 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing PHF20 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PHF20 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PHF20 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for PHF20 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PHF20 gene: Search GeneIP for patents involving PHF20
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for PHF20 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for PHF20 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PHF20 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PHF20 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for PHF20 | | OriGene 3'-UTR Clone for PHF20 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PHF20 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PHF20 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for PHF20 | | OriGene Custom Protein Services for PHF20 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PHF20 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PHF20 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHF20 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PHF20 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHF20 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHF20 |
| |
 |  |  |  | |
| Antibodies & Assays for PHF20  |
| | | Search Tocris compounds for PHF20 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | PHF20 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF20 |
|  |  |  | | | Search ThermoFisher Antibodies for PHF20 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF20 |
|
|
|
|