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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PHF17 Gene

protein-coding   GIFtS: 56
GCID: GC04P129730

PHD Finger Protein 17

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
PHD Finger Protein 171 2 3
JADE12 3
Gene For Apoptosis And Differentiation In Epithelia2
PHD Protein Jade-12
Protein Jade-12
KIAA18073

External Ids:    HGNC: 300271   Entrez Gene: 799602   Ensembl: ENSG000000776847   OMIM: 6105145   UniProtKB: Q6IE813   

Export aliases for PHF17 gene to outside databases

Previous GC identifers: GC04P130190 GC04P130088 GC04P129950 GC04P125461


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for PHF17 Gene: 
PHF17 (PHD finger protein 17) is a protein-coding gene. Diseases associated with PHF17 include von hippel-lindau disease, and kidney cancer. GO annotations related to this gene include protein binding and zinc ion binding. An important paralog of this gene is BRD1.

UniProtKB/Swiss-Prot: JADE1_HUMAN, Q6IE81
Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced
activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional
coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a
renal tumor suppressor

Gene Wiki entry for PHF17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PHF17 gene promoter:
         Sp1   MAZR   MyoD   CUTL1   Nkx2-5   Egr-4   E47   N-Myc   Egr-2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPHF17 promoter sequence
   Search SABiosciences Chromatin IP Primers for PHF17

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHF17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q26-q27   Ensembl cytogenetic band:  4q28.2   HGNC cytogenetic band: 4q26-q27

PHF17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PHF17 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P129730:  view genomic region     (about GC identifiers)

Start:
129,730,779 bp from pter      End:
129,796,379 bp from pter
Size:
65,601 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: JADE1_HUMAN, Q6IE81 (See protein sequence)
Recommended Name: Protein Jade-1  
Size: 842 amino acids; 95533 Da
Subunit: Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15,
PHF16 and PHF17. Isoform 3 interacts with VHL and KAT5
Subcellular location: Cytoplasm. Nucleus
Sequence caution: Sequence=BAB15371.1; Type=Erroneous initiation; Sequence=BAC11335.1; Type=Erroneous initiation;
Secondary accessions: D3DNY0 D3DNY1 Q4W5D5 Q6ZSL7 Q8NC41 Q96JL8 Q96SQ1 Q9H692
Alternative splicing: 3 isoforms:  Q6IE81-1   Q6IE81-2   Q6IE81-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PHF17: NX_Q6IE81

Explore proteomics data for PHF17 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6IE81

  • PHF17 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PHF17 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_079176.2  NP_955352.1  

    ENSEMBL proteins: 
     ENSP00000423737   ENSP00000388015   ENSP00000426590   ENSP00000425730   ENSP00000422445  
     ENSP00000426920   ENSP00000421265   ENSP00000421778   ENSP00000404211   ENSP00000424280  
     ENSP00000425535   ENSP00000226319  

    Human Recombinant Protein Products for PHF17: 
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    Novus Biologicals PHF17 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PHF17 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000123histone acetyltransferase complex IDA16387653
    GO:0005634nucleus IDA12169691
    GO:0005737cytoplasm IDA12169691
    GO:0005739mitochondrion IDA--

    PHF17 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PHF: Zinc fingers, PHD-type

    5/6 InterPro protein domains (see all 6):
     IPR001965 Znf_PHD
     IPR013083 Znf_RING/FYVE/PHD
     IPR019786 Zinc_finger_PHD-type_CS
     IPR011011 Znf_FYVE_PHD
     IPR019542 Enhancer_polycomb-like_N

    Graphical View of Domain Structure for InterPro Entry Q6IE81

    ProtoNet protein and cluster: Q6IE81

    UniProtKB/Swiss-Prot: JADE1_HUMAN, Q6IE81
    Domain: The 2 PHD-type zinc fingers are required for transcriptional activity
    Similarity: Belongs to the JADE family
    Similarity: Contains 2 PHD-type zinc fingers


    PHF17 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: JADE1_HUMAN, Q6IE81
    Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced
    activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional
    coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a
    renal tumor suppressor

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12169691
    GO:0008270zinc ion binding IEA--
         
    PHF17 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for PHF17:
     Decreased viability with pacli  Increased cell death HMECs cel 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Phf17):
     mortality/aging 

    PHF17 for phenotypes           About GeneDecksing

    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PHF17 
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    miRNA
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    miRTarBase miRNAs that target PHF17:
    hsa-mir-155 (MIRT001806)

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    8/105 QIAGEN miScript miRNA Assays for microRNAs that regulate PHF17 (see all 105):
    hsa-miR-3938 hsa-miR-218-1* hsa-miR-578 hsa-miR-502-3p hsa-miR-890 hsa-miR-3613-3p hsa-miR-489 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): PHF17 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PHF17

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/28 Interacting proteins for PHF17 (Q6IE812, 3 ENSP000002263194) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE3AQ050862, 3, ENSP000003810454MINT-8276472 MINT-2876576 I2D: score=4 STRING: ENSP00000381045
    SMN1Q166372, 3MINT-8271388 I2D: score=2 
    SMN2Q166372, 3MINT-8271388 I2D: score=2 
    HMOX2P305192, 3MINT-8258379 I2D: score=2 
    PFDN1O609252, 3MINT-8265974 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006915apoptotic process NAS12169691
    GO:0006950response to stress NAS12169691
    GO:0030308negative regulation of cell growth NAS12169691

    PHF17 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PHF17 (JADE1)

    Search CenterWatch for drugs/clinical trials and news about PHF17 / JADE1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PHF17 gene (2 alternative transcripts): 
    NM_024900.3  NM_199320.2  

    Unigene Cluster for PHF17:

    PHD finger protein 17
    Hs.12420  [show with all ESTs]
    Unigene Representative Sequence: NM_199320
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000511647 ENST00000452328 ENST00000504089 ENST00000512960 ENST00000503785
    ENST00000514740 ENST00000510308 ENST00000511925 ENST00000413543(uc003igj.3 uc003igm.3)
    ENST00000507833 ENST00000508997 ENST00000226319(uc003igk.3 uc003igl.3 uc011cgy.2)

    miRNA
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    8/105 QIAGEN miScript miRNA Assays for microRNAs that regulate PHF17 (see all 105):
    hsa-miR-3938 hsa-miR-218-1* hsa-miR-578 hsa-miR-502-3p hsa-miR-890 hsa-miR-3613-3p hsa-miR-489 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): PHF17 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB058710.1 AF520952.1 AK026132.1 AK027620.1 AK074986.1 AK127326.1 AK297357.1 AK304235.1 
    AK304815.1 BC032376.1 

    14 DOTS entries:

    DT.413933  DT.312111  DT.108704  DT.97810799  DT.95162900  DT.97829487  DT.100775334  DT.100837227 
    DT.121272906  DT.100774543  DT.121272886  DT.92422807  DT.95266680  DT.97829486 

    24/272 AceView cDNA sequences (see all 272):

    AW576270 BI964148 BM908216 Z40571 AK027620 BU726630 AW269233 AI864692 
    CR608541 AA345136 BF431419 AI658994 AI187023 AI073452 BQ219053 F13175 
    AI243053 BG150179 AL701555 AI089485 BU738962 AI278968 AI264117 AL525369 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for PHF17 (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^
    SP1:              -     -     -     -     -     -     -                                   -                                                     -     -         
    SP2:                                                                                                                                            -     -         
    SP3:              -     -     -     -     -     -     -                                                                                                         
    SP4:                                                  -                                                                                                         
    SP5:                                -     -     -     -                                                                                                         

    ExUns: 14a · 14b · 14c
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for PHF17

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PHF17 expression in normal human tissues (normalized intensities)      PHF17 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATGGATTCC
    PHF17 Expression
    About this image


    PHF17 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/25 selected tissues (see all 25) fully expand
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Epithelium (Reproductive System)    fully expand to see all 3 entries
             cervix, uterine ; squamous epithelial cells   
     
     Trophoblast (Extraembryonic Tissues)    fully expand to see all 2 entries
             Trophoblast Cells Trophoblast
             Trophoblast
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   

    See PHF17 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PHF17

    SOURCE GeneReport for Unigene cluster: Hs.12420

    UniProtKB/Swiss-Prot: JADE1_HUMAN, Q6IE81
    Tissue specificity: Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level).
    Down-regulated in renal cancer cells

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF17

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PHF17 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Phf171 , 5 PHD finger protein 171, 5 90.42(n)1
    93.39(a)1
      3 (19.88 cM)5
    2694241  NM_172303.41  NP_758507.31 
     415557345 
    chicken
    (Gallus gallus)
    Aves PHF171 PHD finger protein 17 77.26(n)
    81.53(a)
      422502  XM_003641177.1  XP_003641225.1 
    lizard
    (Anolis carolinensis)
    Reptilia PHF176
    Uncharacterized protein
    77(a)
    1 ↔ 1
    5(136004214-136073986)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.193172 Xenopus laevis transcribed sequence with weak similarity more 76.19(n)    BQ384563.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi11a042 wufi11a04 77.68(n)   327437  BC046874.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta rno6
    rhinoceros
    9(a)
    1 → many
    3L(187207-199762)
    worm
    (Caenorhabditis elegans)
    Secernentea phf-156
    Protein PHF-15, isoform a
    21(a)
    1 → many
    III(3322970-3331726)


    ENSEMBL Gene Tree for PHF17 (if available)
    TreeFam Gene Tree for PHF17 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PHF17 gene
    BRD12  BRPF12  MLLT102  PHF142  PHF152  PHF162  MLLT62  BRPF32  
    4 SIMAP similar genes for PHF17 using alignment to 8 protein entries:     JADE1_HUMAN (see all proteins):
    PHF16    AF10    PHF15    MLL/AF10 fusion

    PHF17 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1317 SNPs in PHF17 are shown (see all 1317)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs131429641,2
    C,F,H--129729064(+) cttaaC/Gaaccc 2 -- us2k122Minor allele frequency- G:0.08NS EA NA WA 2640
    rs1128569191,2
    C--129729147(+) ATCCC-/AACAGG 2 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1814111461,2
    --129729225(+) TTCTAA/CAGAGA 2 -- us2k10--------
    rs100089271,2
    C,F,H--129729239(+) TGTGCA/GAGGTG 2 -- us2k123Minor allele frequency- G:0.26NS EA NA WA CSA 2341
    rs1426102311,2
    --129729273(+) AGTGCA/CATACT 2 -- us2k10--------
    rs131437711,2
    C,F,H--129729412(+) ATATAT/CAGTAC 2 -- us2k120Minor allele frequency- C:0.46NS EA NA WA 2346
    rs1866032611,2
    --129729507(+) TAACGG/TTCTGG 2 -- us2k10--------
    rs1919717831,2
    --129729555(+) ATTACA/GTGAAA 2 -- us2k10--------
    rs1433830671,2
    C--129729604(+) ACATAC/TGCCTT 2 -- us2k10--------
    rs1483864321,2
    --129729652(+) GTTCCC/TATTTA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for PHF17 (129730779 - 129796379 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for PHF17:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv4504CNV Loss18451855
    nsv517249CNV Gain19592680
    nsv822717CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610514    OMIM disorders: --

    4 diseases for PHF17:    About MalaCards
    von hippel-lindau disease    kidney cancer    renal cell carcinoma    leukemia

    1 disease from the University of Copenhagen DISEASES database for PHF17:
    Kidney cancer

    PHF17 for disorders           About GeneDecksing


    Export disorders for PHF17 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PHF17 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with PHF17)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1. (PubMed id 12169691)1, 2, 3, 9 Zhou M.I.... Cohen H.T. (2002)
    2. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2, 3 Nagase T.... Ohara O. (2001)
    3. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. (PubMed id 16387653)1, 2 Doyon Y.... Cote J. (2006)
    4. Jade-1, a candidate renal tumor suppressor that promotes apoptosis. (PubMed id 16046545)1, 2 Zhou M.I....Cohen H.T. (2005)
    5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. von Hippel-Lindau partner Jade-1 is a transcriptional co-activator associated with histone acetyltransferase activity. (PubMed id 15502158)1, 2 Panchenko M.V.... Cohen H.T. (2004)
    9. Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development. (PubMed id 14612400)1, 2 Tzouanacou E.... Wilson V. (2003)
    10. Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. (PubMed id 18806787)1, 9 Chitalia V.C....Cohen H.T. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79960 HGNC: 30027 AceView: PHF17 Ensembl:ENSG00000077684 euGenes: HUgn79960
    ECgene: PHF17 H-InvDB: PHF17

    (According to HUGE)
    About This Section
    HUGE: KIAA1807

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PHF17 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PHF17 gene:
    Search GeneIP for patents involving PHF17

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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