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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PHF16 Gene

protein-coding   GIFtS: 51
GCID: GC0XP046771

PHD Finger Protein 16

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
PHD Finger Protein 161 2 3
JADE32 3
Protein Jade-32
KIAA02153

External Ids:    HGNC: 229821   Entrez Gene: 97672   Ensembl: ENSG000001022217   OMIM: 3006185   UniProtKB: Q926133   
ORGUL members:         
NONCODE14:n337672      

Export aliases for PHF16 gene to outside databases

Previous GC identifers: GC0XP045598 GC0XP045817 GC0XP046528 GC0XP046656 GC0XP044482


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PHF16 Gene:
This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers.
The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative
splicing results in multiple transcript variants encoding the same protein. (provided by RefSeq, Aug 2013)

GeneCards Summary for PHF16 Gene: 
PHF16 (PHD finger protein 16) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with PHF16 include breast cancer, and leukemia. GO annotations related to this gene include zinc ion binding. An important paralog of this gene is PHF15.

UniProtKB/Swiss-Prot: JADE3_HUMAN, Q92613
Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced
activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo

Gene Wiki entry for PHF16 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_079573.4  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PHF16 gene promoter:
         E2F-3a   E2F-4   E2F-5   E2F   E2F-1   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPHF16 promoter sequence
   Search SABiosciences Chromatin IP Primers for PHF16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHF16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.3

PHF16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PHF16 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP046771:  view genomic region     (about GC identifiers)

Start:
46,771,711 bp from pter      End:
46,920,641 bp from pter
Size:
148,931 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: JADE3_HUMAN, Q92613 (See protein sequence)
Recommended Name: Protein Jade-3  
Size: 823 amino acids; 93808 Da
Subunit: Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15,
PHF16 and PHF17
Sequence caution: Sequence=BAA13205.2; Type=Erroneous initiation;
Secondary accessions: Q6IE79

Explore the universe of human proteins at neXtProt for PHF16: NX_Q92613

Explore proteomics data for PHF16 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q92613

  • PHF16 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PHF16 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001070913.1  NP_055550.1  

    ENSEMBL proteins: 
     ENSP00000391009   ENSP00000218343   ENSP00000400584   ENSP00000380373  

    Human Recombinant Protein Products for PHF16: 
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    Novus Biologicals PHF16 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PHF16 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000123histone acetyltransferase complex IDA16387653

    PHF16 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for PHF16


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PHF: Zinc fingers, PHD-type

    5/6 InterPro protein domains (see all 6):
     IPR001965 Znf_PHD
     IPR013083 Znf_RING/FYVE/PHD
     IPR019786 Zinc_finger_PHD-type_CS
     IPR011011 Znf_FYVE_PHD
     IPR019542 Enhancer_polycomb-like_N

    Graphical View of Domain Structure for InterPro Entry Q92613

    ProtoNet protein and cluster: Q92613

    UniProtKB/Swiss-Prot: JADE3_HUMAN, Q92613
    Similarity: Belongs to the JADE family
    Similarity: Contains 1 PHD-type zinc finger


    PHF16 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: JADE3_HUMAN, Q92613
    Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced
    activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo
    Induction: By estradiol in estrogen-responsive breast cancer cells

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    PHF16 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PHF16:
     Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Phf16):
     normal 

    PHF16 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PHF16 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PHF16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PHF16 
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    miRNA
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    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate PHF16 (see all 10):
    hsa-miR-30c hsa-miR-205 hsa-miR-607 hsa-miR-30d hsa-miR-30a hsa-miR-670 hsa-miR-30b hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidPHF16 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF16


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PHF16

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for PHF16 (Q926133 ENSP000002183434) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ING4Q9UNL43, ENSP000003800244I2D: score=1 STRING: ENSP00000380024
    KAT7O952513, ENSP000002590214I2D: score=1 STRING: ENSP00000259021
    ING5Q8WYH83, ENSP000003221424I2D: score=1 STRING: ENSP00000322142
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043966histone H3 acetylation IDA16387653
    GO:0043981histone H4-K5 acetylation IDA16387653
    GO:0043982histone H4-K8 acetylation IDA16387653
    GO:0043983histone H4-K12 acetylation IDA16387653
    GO:0043984NOT histone H4-K16 acetylation IDA16387653

    PHF16 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PHF16 (JADE3)

    Search CenterWatch for drugs/clinical trials and news about PHF16 / JADE3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PHF16 gene (2 alternative transcripts): 
    NM_001077445.2  NM_014735.4  

    Unigene Cluster for PHF16:

    PHD finger protein 16
    Hs.371977  [show with all ESTs]
    Unigene Representative Sequence: D86969
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000424392 ENST00000218343(uc004dgy.3) ENST00000455411 ENST00000397189(uc004dgx.3)

    miRNA
    Products:
         
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    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate PHF16 (see all 10):
    hsa-miR-30c hsa-miR-205 hsa-miR-607 hsa-miR-30d hsa-miR-30a hsa-miR-670 hsa-miR-30b hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidPHF16 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PHF16
    Clone
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    OriGene ORF clones in mouse, rat for PHF16
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    GenScript: all cDNA clones in your preferred vector (see all 2): PHF16 (NM_001077445)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PHF16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PHF16
    Sirion Biotech Customized lentivirus for stable overexpression of PHF16 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PHF16
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PHF16

    Additional mRNA sequence: 

    AF127774.1 AK291220.1 BC113880.1 BC114487.1 D86969.1 

    4 DOTS entries:

    DT.413585  DT.97838422  DT.121289853  DT.100745292 

    1 AceView cDNA sequence:

    AL703879 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PHF16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTTTCAATT
    PHF16 Expression
    About this image


    See PHF16 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PHF16

    SOURCE GeneReport for Unigene cluster: Hs.371977

    UniProtKB/Swiss-Prot: JADE3_HUMAN, Q92613
    Tissue specificity: Ubiquitously expressed, with highest levels in placenta and uterus

        SABiosciences Custom PCR Arrays for PHF16
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PHF16 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Phf161 , 5 PHD finger protein 161, 5 84.89(n)1
    82.02(a)1
      X (15.90 cM)5
    3822071  NM_199317.11  NP_955021.11 
     204256885 
    chicken
    (Gallus gallus)
    Aves PHF161 PHD finger protein 16 74.58(n)
    74.58(a)
      418674  XM_416870.3  XP_416870.3 
    lizard
    (Anolis carolinensis)
    Reptilia PHF166
    Uncharacterized protein
    73(a)
    1 ↔ 1
    3(112070066-112091310)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.5662 Transcribed sequence with moderate similarity to protein more 77.81(n)    AL864925.2 
    zebrafish
    (Danio rerio)
    Actinopterygii jade32 jade3 protein 77.72(n)   387595  BC045468.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta rno6
    rhinoceros
    10(a)
    1 → many
    3L(187207-199762)
    worm
    (Caenorhabditis elegans)
    Secernentea phf-156
    Protein PHF-15, isoform a
    22(a)
    1 → many
    III(3322970-3331726)


    ENSEMBL Gene Tree for PHF16 (if available)
    TreeFam Gene Tree for PHF16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PHF16 gene
    PHF152  PHF142  PHF172  BRD12  BRPF12  MLLT62  MLLT102  BRPF32  
    2 SIMAP similar genes for PHF16 using alignment to 3 protein entries:     JADE3_HUMAN (see all proteins):
    PHF17    PHF15

    PHF16 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1378/1703 SNPs in PHF16 are shown (see all 1703)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1901627601,2
    --44481243(+) TCTACA/GTTAAT 2 -- us2k10--------
    rs1857298661,2
    --46688831(+) GAAATG/TACAAA 1 -- us2k10--------
    rs1126976861,2
    F--46688892(+) AAAGCA/GGTGAC 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs1809595801,2
    --46689337(+) GTAAAC/TGAAAA 2 -- us2k10--------
    rs1854335871,2
    --46689801(+) AAGGTC/TTGTTG 2 -- us2k10--------
    rs59062891,2
    C--46689878(+) atataC/Tacaca 2 -- us2k11Minor allele frequency- T:0.00NA 2
    rs1997573501,2
    --46689898(+) TATAT-/ATAC  
            
    ATACA
    2 -- us2k10--------
    rs1390683211,2
    --46689995(+) AAGAAC/TGCGTG 2 -- us2k10--------
    rs1498812191,2
    C--46690045(+) CTTCGA/GAGCTA 2 -- us2k10--------
    rs1909712901,2
    --46690214(+) CTGATA/TGAAAG 2 -- us2k10--------
    rs1448751671,2
    --46690434(+) ACTGAA/CTAAAT 2 -- us2k10--------
    rs1840666941,2
    --46690599(+) ACAGCC/TGAGGC 2 -- us2k10--------
    rs1873803331,2
    --46690616(+) ACCTCC/GTCCTC 2 -- us2k10--------
    rs1915963841,2
    --46691129(+) CTCACC/TCGGCA 2 -- ut51 int10--------
    rs78837051,2
    C,F--46691933(+) TCCGGG/TGAAAT 2 -- int11Minor allele frequency- T:0.50WA 2
    rs3735158151,2
    C--46692159(+) GCCTGA/CTTTGT 2 -- int10--------
    rs352478761,2
    C,F--46692346(+) CCTCAG/TATGTG 2 -- int13Minor allele frequency- T:0.25NA 8
    rs1486965251,2
    C--46692400(+) TGAAGC/TTGAGG 2 -- int10--------
    rs1870860091,2
    --46692414(+) AGATTC/TCCCCC 2 -- int10--------
    rs1917978011,2
    --46692440(+) GTGTAA/CGAAGT 2 -- int10--------
    rs1824740231,2
    --46692555(+) AGTAAA/TGAAAA 2 -- int10--------
    rs117980221,2
    H--46692601(+) GCTTAG/TTTTAA 2 -- int14Minor allele frequency- T:0.00NS EA 418
    rs117984111,2
    H--46692681(+) GCCTAG/TGCTGG 2 -- int10--------
    rs1867871201,2
    --46692692(+) GAGGGA/GGAAAG 2 -- int10--------
    rs1927024631,2
    --46692806(+) CGTACA/CCTTTG 2 -- int10--------
    rs66113131,2
    C--46692822(+) TGTGGT/CTCTCA 2 -- int12Minor allele frequency- C:0.00NA 4
    rs3774585401,2
    C--46693012(+) TGAGAC/TGTTGA 2 -- int10--------
    rs117985891,2
    C,F,H--46693053(+) ACTTTC/TAATCG 2 -- int15Minor allele frequency- T:0.00NS EA NA 422
    rs1855606911,2
    --46693078(+) CTTTGC/TCACCT 2 -- int10--------
    rs1904623351,2
    --46693173(+) TCAATC/TCTGGA 2 -- int10--------
    rs1929388001,2
    --46693207(+) TCTAGA/GATTCA 2 -- int10--------
    rs59062901,2
    C,F,H--46693326(+) GAAGTG/TTTGTG 2 -- int17Minor allele frequency- T:0.01NS EA NA 786
    rs1844329641,2
    --46693374(+) AGGACA/TGGTGA 2 -- int10--------
    rs1889972991,2
    --46693600(+) ACTAGG/TCAAGT 2 -- int10--------
    rs1813906331,2
    --46693620(+) GAGGTG/TGGGGA 2 -- int10--------
    rs1478346911,2
    C--46693669(+) GGGAGA/GGCTCT 2 -- int10--------
    rs1856702191,2
    --46693846(+) TTACTA/GTGATC 2 -- int10--------
    rs1413297511,2
    --46693898(+) GACACC/TTGTCT 2 -- int10--------
    rs1893622141,2
    --46693920(+) AACATA/GGGGAC 2 -- int10--------
    rs1120029131,2
    C,F--46693957(+) GTTCCT/AGTTAC 2 -- int11Minor allele frequency- A:0.00CSA 1
    rs1510651261,2
    --46694133(+) TCATGA/GTTATT 2 -- int10--------
    rs1409703011,2
    C--46694386(+) TTCATC/TAATGC 2 -- int10--------
    rs1806906571,2
    C--46694416(+) TTAATA/CTTTGC 2 -- int10--------
    rs1872177291,2
    C--46694592(+) ATACAA/CTAGAC 2 -- int10--------
    rs1921689231,2
    --46694670(+) AACTGC/TTATAA 2 -- int10--------
    rs1831602501,2
    C--46694786(+) ACTGAA/GATTTA 2 -- int10--------
    rs1860009581,2
    --46695167(+) TAATTC/TATTCA 2 -- int10--------
    rs1904596041,2
    --46695586(+) CTGAGA/GGTGGT 2 -- int10--------
    rs1501981791,2
    C--46695593(+) TGGTAA/GTGAGA 2 -- int10--------
    rs1826905071,2
    --46695624(+) CATTCA/GTTTCA 2 -- int10--------
    rs1880642311,2
    --46695711(+) GGGGGC/TGGGTG 2 -- int10--------
    rs1908102531,2
    --46695726(+) TGGCTC/TGGTGT 2 -- int10--------
    rs1826634971,2
    --46695977(+) AGGGAC/GACCAG 2 -- int10--------
    rs1888709501,2
    --46695998(+) TGAGCC/TTTGAG 2 -- int10--------
    rs1926143181,2
    --46696019(+) AATAAA/GCAAGG 2 -- int10--------
    rs1848632181,2
    --46696106(+) TGGAAA/GGGATC 2 -- int10--------
    rs1876578641,2
    --46696198(+) AAGAGC/TTTGTG 2 -- int10--------
    rs1921454121,2
    --46696253(+) TCTCTC/GTCTAA 2 -- int10--------
    rs1841916961,2
    --46696401(+) CCAGGA/GAAGCA 2 -- int10--------
    rs1387038011,2
    C--46696590(+) AGAATA/GCTTCT 2 -- int10--------
    rs1407375881,2
    --46696673(+) CTGATC/TCCTGT 2 -- int10--------
    rs1896929781,2
    --46696981(+) TTCTTA/TTCTAC 2 -- int10--------
    rs1458917811,2
    C--46697021(+) GTTCTC/GTTCCC 2 -- int10--------
    rs1809495641,2
    --46697186(+) TAAGCC/TGGGAT 2 -- int10--------
    rs1845864261,2
    --46697326(+) TGTGTA/CACATT 2 -- int10--------
    rs1891091011,2
    --46697336(+) TTGCTA/GTTGTC 2 -- int10--------
    rs1820073261,2
    --46697456(+) ACTGCA/GATAAT 2 -- int10--------
    rs1862344231,2
    --46697648(+) GGTTTC/TGGACA 2 -- int10--------
    rs1384527941,2
    C--46697722(+) CTAGAC/TTTCCT 2 -- int10--------
    rs766207261,2
    C--46697726(+) ATTTCC/TTCAAC 2 -- int10--------
    rs59062931,2
    C,H--46697782(+) ACTAGG/ATTTTG 2 -- int112Minor allele frequency- A:0.00NS EA WA NA CSA 432
    rs1461099401,2
    C--46697874(+) TTTATA/GTGATT 2 -- int10--------
    rs1905001561,2
    C--46698174(+) AGGAAA/GTATGT 2 -- int10--------
    rs1813850071,2
    --46698190(+) AAACTA/GTACAA 2 -- int10--------
    rs1480118171,2
    --46698545(+) ACATAA/GACTTT 2 -- int10--------
    rs1863958051,2
    --46698578(+) AGCAAG/TGTGAA 2 -- int10--------
    rs1913199901,2
    --46698581(+) AATGTG/TAATAT 2 -- int10--------
    rs1829038831,2
    --46698654(+) CCATAA/GACTCC 2 -- int10--------
    rs59055731,2
    C,F,A,H--46698735(+) CCTCAT/CGATAG 2 -- int122Minor allele frequency- C:0.12NS EA NA WA CSA 2084
    rs1880159171,2
    --46698938(+) GTCGAA/GGGACG 2 -- int10--------
    rs1505186601,2
    --46699096(+) AAACTA/GTGTTC 2 -- int10--------
    rs1445644491,2
    --46699186(+) TGTTGA/TAAAGA 2 -- int10--------
    rs1474316741,2
    --46699245(+) TGACTA/GTCCTT 2 -- int10--------
    rs1898205061,2
    --46699394(+) TTCTCA/TCAGGG 2 -- int10--------
    rs59529711,2
    C,H--46699411(+) TAAGTT/CACTTT 2 -- int16Minor allele frequency- C:0.00NS EA NA 410
    rs1835581321,2
    --46699481(+) TCTTGA/GTCTTA 2 -- int10--------
    rs1452501811,2
    --46699844(+) CTGCAC/GCTGGC 2 -- int10--------
    rs1877035141,2
    --46699995(+) AAGAGC/TTAACA 2 -- int10--------
    rs1449843171,2
    --46700102(+) AAGATG/TATATT 2 -- int10--------
    rs1491717721,2
    --46700132(+) TTCCAA/GTGCTT 2 -- int10--------
    rs1922008051,2
    --46700427(+) GGATAC/TATGTA 2 -- int10--------
    rs1851489641,2
    --46700624(+) ACCCAC/TGAATG 2 -- int10--------
    rs45499001,2
    C--46700631(+) aatgaG/Aaacat 2 -- int11Minor allele frequency- A:0.00NA 2
    rs1882876221,2
    --46700650(+) TGGCTC/GTCTGT 2 -- int10--------
    rs1929783831,2
    --46700936(+) TTTCTC/GTTTCT 2 -- int10--------
    rs1847092881,2
    --46700985(+) GCCCCA/GCAGTT 2 -- int10--------
    rs1896422171,2
    --46701027(+) CTTTTG/TAATTT 2 -- int10--------
    rs1806727111,2
    --46701207(+) GTCTTC/GCATAT 2 -- int10--------
    rs1847321351,2
    --46701218(+) TGTCTA/GTTTTT 2 -- int10--------
    rs66113151,2
    H--46701636(+) gctccA/Cccatg 2 -- int14Minor allele frequency- C:0.00NS EA 384
    rs1423323081,2
    --46701661(+) AAGATA/CTTTTG 2 -- int10--------
    rs1891853081,2
    --46701676(+) GATGGA/GGTTTC 2 -- int10--------
    rs66094441,2
    H--46701703(+) taggtC/Ttggaa 2 -- int14Minor allele frequency- T:0.00NS EA 418
    rs1816023421,2
    --46701715(+) TCCTGG/TGTTCA 2 -- int10--------
    rs66094471,2
    C,A,H--46701773(+) gagccA/Cctgcg 2 -- int10--------
    rs1870953871,2
    --46701777(+) CACTGC/TGCCCA 2 -- int10--------
    rs578475671,2
    C--46701865(+) TCTCT-/CTCTTTTTTTTT
    TT
    /TCTCTCTTTTT
    TTTTT
    2 -- int10--------
    rs1512595471,2
    --46701937(+) TGACAC/TGATCA 2 -- int10--------
    rs1915249271,2
    --46701938(+) GACACA/GATCAT 2 -- int10--------
    rs70576931,2
    C--46702005(+) agcctC/Tctgag 2 -- int10--------
    rs1456152001,2
    C--46702025(+) CCACAA/GGTGCA 2 -- int10--------
    rs59062941,2
    H--46702102(+) tctggT/Gcttga 2 -- int14Minor allele frequency- G:0.00NS EA 416
    rs1815817311,2
    --46702164(+) TACAGG/TCATGA 2 -- int10--------
    rs1863387291,2
    --46702464(+) TGGAGC/GTTCTT 2 -- int10--------
    rs3682275051,2
    C--46702553(+) CCCCCA/GAGACT 2 -- int10--------
    rs1898588781,2
    --46703301(+) GTCACG/TGAAAA 2 -- int10--------
    rs1821295481,2
    --46703382(+) CACATC/TGCCAG 2 -- int10--------
    rs1864890391,2
    --46703461(+) TAGAAC/TACAAA 2 -- int10--------
    rs1911430921,2
    --46703748(+) GCTGTA/GTGAAA 2 -- int10--------
    rs1838022791,2
    --46703944(+) TTAGTG/TGTCAG 2 -- int10--------
    rs1413941161,2
    C--46704018(+) CTGGGC/TGCAGT 2 -- int10--------
    rs1888191361,2
    --46704168(+) CAGGCA/GCCTGT 2 -- int10--------
    rs2007828821,2
    --46704325(+) TTGAC-/TTTTTT 2 -- int10--------
    rs2013543751,2
    C--46704492(+) AGCTA-/ATTTTATTT
    TATTTTATTTT
    ATTTT
    2 -- int10--------
    rs1928954761,2
    --46704743(+) AAGACA/TGGGTG 2 -- int10--------
    rs59062951,2
    C,F,A,H--46704861(+) aggcaT/Cgcatt 2 -- int110Minor allele frequency- C:0.09NS EA NA WA CSA 427
    rs1832784491,2
    --46705072(+) ATCCAC/TCACAA 2 -- int10--------
    rs43826021,2
    C,F,H--46705137(+) gtcatA/Gctctc 2 -- int18Minor allele frequency- G:0.01NS EA NA 790
    rs46456671,2
    C,F,H--46705368(+) TAATCA/GTTCAC 2 -- int16Minor allele frequency- G:0.00NS EA NA 524
    rs1494944561,2
    C--46705424(+) GAGCCA/GCTATA 2 -- int10--------
    rs1868464001,2
    --46705516(+) GTACTA/TCCATT 2 -- int10--------
    rs1913349171,2
    --46705526(+) TCATGA/GTAAAA 2 -- int10--------
    rs1439501811,2
    --46705781(+) TTTTTA/GTGAGA 2 -- int10--------
    rs1835192261,2
    --46705793(+) ACATTA/CATCTT 2 -- int10--------
    rs104818371,2
    C,F,A,H--46705831(+) AATCTA/GTAAGT 2 -- int120Minor allele frequency- N:0.00NS EA NA WA 2188
    rs1880765321,2
    --46706087(+) GTGAAC/TACTTA 2 -- int10--------
    rs1427028431,2
    C--46706121(+) TTTGGA/CCTCAG 2 -- int10--------
    rs1932891811,2
    --46706488(+) CACATG/TGTACA 2 -- int10--------
    rs785542381,2
    C--46706578(+) AGAGAC/TGTCAC 2 -- int10--------
    rs125601791,2
    C,F,H--46706617(+) TCTCCC/TGTACC 2 -- int1 trp310Minor allele frequency- T:0.03NS EA NA 838
    rs1855298911,2
    --46706630(+) CAACAA/GTCCAA 2 -- int10--------
    rs1904315781,2
    --46706646(+) ATGTTC/TACCTG 2 -- int10--------
    rs1814823281,2
    --46707056(+) TGTGTG/TTTTTG 2 -- int10--------
    rs1397874471,2
    --46707095(+) GTCACC/TGAGGC 2 -- int10--------
    rs1865964631,2
    --46707157(+) CAAGCA/GATTGT 2 -- int10--------
    rs1885478551,2
    --46707243(+) TTTTGC/TTTTGT 2 -- int10--------
    rs1809537281,2
    --46707258(+) TTTTGC/TTTTTT 2 -- int10--------
    rs1854417651,2
    --46707695(+) CTCACA/GTGAAA 2 -- int10--------
    rs1898055771,2
    --46707788(+) AGAAAA/CTTTTT 2 -- int10--------
    rs1842342171,2
    --46707799(+) TCTTTC/TTTTAG 2 -- int10--------
    rs1869918171,2
    --46708001(+) ACTCAA/GCTTCC 2 -- int10--------
    rs1452833181,2
    C--46708261(+) ATACCA/GTGAGT 2 -- int10--------
    rs59062961,2
    C,H--46708265(+) CATGAG/ATCATT 2 -- int15Minor allele frequency- A:0.00NS EA NA 412
    rs1918978871,2
    C--46708283(+) TCTGCC/TTCTGC 2 -- int10--------
    rs1505722391,2
    C--46708678(+) GGCAAC/TCATGT 2 -- int10--------
    rs1832921281,2
    --46708699(+) CAGCTA/CACCTG 2 -- int10--------
    rs1395659641,2
    --46708782(+) AAGCCA/GTCTTA 2 -- int10--------
    rs1870830591,2
    --46708840(+) GGACCA/CCAGAA 2 -- int10--------
    rs1917899221,2
    --46709004(+) ATCCCC/TAGGGC 2 -- int10--------
    rs1824801891,2
    --46709369(+) CCCCCC/GATCCA 2 -- int10--------
    rs48245961,2
    C,F,H--46709387(+) AACGCT/GCACTA 2 -- int115Minor allele frequency- G:0.01NS EA WA NA CSA 922
    rs78781441,2
    C,F,A,H--46709468(+) ggaaaG/Agaagg 2 -- int1 trp39Minor allele frequency- A:0.06NS EA NA WA 1092
    rs1868048601,2
    --46709723(+) CCAGCA/GACTAC 2 -- int10--------
    rs1923168471,2
    --46709784(+) AACAAA/TTATGC 2 -- int10--------
    rs1395790101,2
    --46709794(+) CCTGGA/GACTTT 2 -- int10--------
    rs1857002071,2
    --46710186(+) ACTACA/GCCCAG 2 -- int10--------
    rs1902279091,2
    --46710292(+) GTTACC/TATGTG 2 -- int10--------
    rs1931713491,2
    --46710321(+) TGAAAA/GTAAAC 2 -- int10--------
    rs1844328041,2
    --46710333(+) TGCATA/TTAATA 2 -- int10--------
    rs171474341,2
    C,F,H--46710370(+) CTTGTA/GTACCA 2 -- int120Minor allele frequency- G:0.09NA NS EA WA 1934
    rs1465388951,2
    --46710522(+) AAATAC/TGTAAG 2 -- int10--------
    rs1414571341,2
    C--46710662(+) AGTGTC/TGTACT 2 -- int10--------
    rs1890066421,2
    C--46710837(+) AAGAAA/GTTATC 2 -- int10--------
    rs1814038541,2
    C--46711163(+) AGCACC/TTTCAA 2 -- int10--------
    rs1856893221,2
    --46711226(+) GGATAA/CCTCTG 2 -- int10--------
    rs1894683541,2
    --46711446(+) ATAAAA/GTAACT 2 -- int10--------
    rs1433891281,2
    --46711589(+) GAACAA/GCATAA 2 -- int10--------
    rs3707014981,2
    C--46711811(+) GGAGTA/CTGCAA 2 -- int10--------
    rs1513123671,2
    C--46711908(+) GCAGAG/TAACCA 2 -- int10--------
    rs1806973401,2
    C--46712059(+) TCATAC/TAAAAG 2 -- int10--------
    rs1405517351,2
    --46712221(+) AAAAAC/GAAAAA 2 -- int10--------
    rs1504448801,2
    --46712238(+) TATTTA/GATGTT 2 -- int10--------
    rs1874551401,2
    --46712416(+) CCCAAA/GTATTA 2 -- int10--------
    rs1918599201,2
    C--46712554(+) TTTTGC/TATGTA 2 -- int10--------
    rs59524081,2
    C,F,H--46712585(+) aatggT/Cgtcat 2 -- int17Minor allele frequency- C:0.02NS EA NA WA 422
    rs66113161,2
    H--46712625(+) tttaaG/Cacgga 2 -- int14Minor allele frequency- C:0.00NS EA 398
    rs1427359921,2
    --46712628(+) AAGACA/GGAGTC 2 -- int10--------
    rs1822889131,2
    C--46712829(+) AGTGGC/TGCGAT 2 -- int10--------
    rs1860076611,2
    --46712854(+) AGCTCC/TGCCTC 2 -- int10--------
    rs1904726371,2
    --46713019(+) CGCCTC/TGGCCT 2 -- int10--------
    rs1827100351,2
    --46713031(+) CCAAAG/TTGCTG 2 -- int10--------
    rs1868462021,2
    --46713064(+) CGCCCA/GGCCTT 2 -- int10--------
    rs1910662711,2
    --46713421(+) GGTTTA/GTTCTC 2 -- int10--------
    rs1824366151,2
    C--46713452(+) GCTGGC/TGTGTA 2 -- int10--------
    rs782621631,2
    C,F--46713527(+) GCTTCG/ACAAGT 2 -- int11Minor allele frequency- A:0.50NA 8
    rs1891468271,2
    --46713576(+) TTTTTA/GTATTT 2 -- int10--------
    rs1931296971,2
    --46713593(+) GAGACA/GGGGTT 2 -- int10--------
    rs1848714721,2
    --46713879(+) TGTCTC/TTCTCT 2 -- int10--------
    rs1876709041,2
    --46713914(+) ACCAGG/TCTGTG 2 -- int10--------
    rs2021176251,2
    C--46713938(+) CAGGC-/CACACAG 2 -- int10--------
    rs1919643171,2
    --46714119(+) GGAACA/GGTTTC 2 -- int10--------
    rs1842088891,2
    --46714155(+) CCGTCC/TGTGGA 2 -- int10--------
    rs1894221801,2
    --46714325(+) AGGCAA/TGGTTT 2 -- int10--------
    rs1809811351,2
    --46714339(+) TCTGTC/TACCCA 2 -- int10--------
    rs1844525581,2
    --46714367(+) GTGAAC/TACGGC 2 -- int10--------
    rs66113171,2
    C,A,H--46714470(+) TttaaT/Cgtggt 2 -- int17Minor allele frequency- C:0.00NA WA CSA 10
    rs1820153381,2
    --46714509(+) TGAGAC/TAGAGT 2 -- int10--------
    rs1378880041,2
    --46714535(+) AGGCTA/GGAGTG 2 -- int10--------
    rs1862524601,2
    --46714573(+) CCTCCA/GCTTCC 2 -- int10--------
    rs1495477401,2
    C--46714587(+) GTTCAA/GGCAAT 2 -- int10--------
    rs1441423871,2
    C--46714613(+) TCCTGA/GGTAGC 2 -- int10--------
    rs117980861,2
    C,H--46714671(+) tagtaA/Gaaacg 2 -- int10--------
    rs1126516441,2
    C,F--46714673(+) GTAGAG/AACGGG 2 -- int11Minor allele frequency- A:0.50WA 2
    rs1139886631,2
    C,F--46714683(+) GGTTTC/TGCCAT 2 -- int11Minor allele frequency- T:0.50WA 2
    rs1855361051,2
    --46714687(+) TCGCCA/GTGTTG 2 -- int10--------
    rs1131067751,2
    C,F--46714697(+) GGCCAG/AGCTGG 2 -- int11Minor allele frequency- A:0.50WA 2
    rs1910713931,2
    --46715149(+) TTTCAA/GTGAGT 2 -- int10--------
    rs1831877391,2
    --46715171(+) GTTATC/TTACAG 2 -- int10--------
    rs1877324671,2
    --46715224(+) TTCATA/CGTGTC 2 -- int10--------
    rs736302451,2
    C,F--46715495(+) AGTGTG/AGGTTG 2 -- int11Minor allele frequency- A:0.00WA 2
    rs1910124931,2
    --46715522(+) TTTCCC/TCCTAA 2 -- int10--------
    rs59062971,2
    C,F,A,H--46715750(+) ggtcaG/Aggaac 2 -- int114Minor allele frequency- A:0.21NS EA NA 1981
    rs48245971,2
    C,F,A,H--46715804(+) tttatG/Catcta 2 -- int19Minor allele frequency- C:0.21NS EA NA 562
    rs1132146281,2
    C,F--46715873(+) TGTACG/ATGTCA 2 -- int11Minor allele frequency- A:0.00CSA 1
    rs59062981,2
    C,F,A,H--46715888(+) atgacA/Ggttga 2 -- int116Minor allele frequency- G:0.44NS EA NA CSA 1687
    rs1400222981,2
    C--46716024(+) TTCACA/GTATTT 2 -- int10--------
    rs1833782261,2
    --46716122(+) GCATCC/GCTCTT 2 -- int10--------
    rs787445671,2
    C--46716175(+) CAGGCA/GTGGTG 2 -- int10--------
    rs749304331,2
    C--46716186(+) GCTCAC/TGCCTG 2 -- int10--------
    rs1877208311,2
    --46716219(+) CGAGGC/TGGGCA 2 -- int10--------
    rs120143711,2
    C,H--46716220(+) gaggcG/Aggcag 2 -- int11Minor allele frequency- A:0.25NA 4
    rs59055741,2
    C,H--46716310(+) cgggcG/Atggtg 2 -- int17Minor allele frequency- A:0.00NA WA CSA 12
    rs1922071111,2
    --46716471(+) TAAATA/TGTTTC 2 -- int10--------
    rs59055751,2
    C,F,H--46716481(+) cttttG/Aatcag 2 -- int114Minor allele frequency- A:0.01NS EA WA NA CSA 634
    rs625913021,2
    C,F--46716504(+) ATATCG/TTTTTC 2 -- int11Minor allele frequency- T:0.00NA 2
    rs1844143811,2
    --46717073(+) ATCCAA/GATATT 2 -- int10--------
    rs1885648121,2
    --46717194(+) GCTATA/GAATTC 2 -- int10--------
    rs1927697391,2
    --46717273(+) CAAACA/GTGTTG 2 -- int10--------
    rs1848536291,2
    --46717351(+) TGTGCA/GGTAGC 2 -- int10--------
    rs45671791,2
    C,F,A,H--46717858(+) GCTTGG/ACATCA 2 -- int118Minor allele frequency- A:0.04NS EA NA 1650
    rs1893676721,2
    --46717951(+) CCTGCC/TCTCTT 2 -- int10--------
    rs1806904151,2
    C--46718044(+) ACATAC/TCTAGT 2 -- int10--------
    rs1847515441,2
    --46718245(+) GAGCAC/TGATTG 2 -- int10--------
    rs43486231,2
    C,H--46718359(+) GAATAT/GTTCAT 2 -- int112Minor allele frequency- G:0.00NS EA WA NA CSA 428
    rs1891936941,2
    --46718405(+) GTCCAC/TAAGTC 2 -- int10--------
    rs1816101281,2
    C--46718537(+) CTGATA/TAGCCC 2 -- int10--------
    rs1868930261,2
    --46718562(+) TCGCTA/GACTCC 2 -- int10--------
    rs1412629031,2
    C--46718824(+) AAAGTC/TGGAGT 2 -- int10--------
    rs1901854661,2
    --46718837(+) TTTCTA/GCCTAG 2 -- int10--------
    rs1814534471,2
    --46719002(+) GTTACC/TTAGTT 2 -- int10--------
    rs1863069301,2
    --46719249(+) CTTCTG/TTTCAA 2 -- int10--------
    rs1469554301,2
    --46719518(+) GTGAGC/TATAGT 2 -- int10--------
    rs1379570301,2
    C--46719598(+) TGTGTG/TTACCC 2 -- int10--------
    rs1898829581,2
    --46719627(+) ATAGAC/TGACAA 2 -- int10--------
    rs1821455461,2
    --46719704(+) TGCAGA/CGAACA 2 -- int10--------
    rs1864978241,2
    --46719729(+) TTTATA/GGCTAC 2 -- int10--------
    rs1911350871,2
    --46719745(+) ATTCTA/GTGGTA 2 -- int10--------
    rs1416327571,2
    C--46719795(+) GATACC/TGTGTC 2 -- int10--------
    rs1500778271,2
    --46719879(+) TTGGGC/TGATAT 2 -- int10--------
    rs1833124761,2
    --46720569(+) CTTATA/GGATTC 2 -- int10--------
    rs1885319531,2
    C--46720690(+) AGGTCC/TCACTG 2 -- int10--------
    rs1931534361,2
    --46720730(+) TTGAAA/GACTTA 2 -- int10--------
    rs1830227521,2
    --46720941(+) TTCCCC/TGTTGC 2 -- int10--------
    rs59529731,2
    C,A--46721001(+) tttctA/Gggttt 2 -- int13Minor allele frequency- G:0.00NA CSA 3
    rs1881112081,2
    --46721141(+) TGGCTA/GTTTAG 2 -- int10--------
    rs769779701,2
    C,F--46721146(-) AGAACG/CTAAAA 2 -- int12Minor allele frequency- C:0.50WA 4
    rs1913551351,2
    --46721150(+) AGGCTC/TTTTTT 2 -- int10--------
    rs2000354601,2
    --46721155(+) CTTTT-/TTGTTGTT 2 -- int10--------
    rs1835267811,2
    C--46721352(+) AGCAGC/TGTTTT 2 -- int10--------
    rs1880706871,2
    --46721407(+) TTCTAC/GGTATT 2 -- int10--------
    rs1462517451,2
    --46721514(+) ATATAC/TTGATT 2 -- int10--------
    rs1926457511,2
    --46721574(+) GAATTA/CTTTAG 2 -- int10--------
    rs1856692651,2
    --46721646(+) TTTGGA/TTGCCT 2 -- int10--------
    rs1899952441,2
    --46721690(+) AAGACC/TCCTGG 2 -- int10--------
    rs1816319501,2
    --46721822(+) CTTATG/TATTTT 2 -- int10--------
    rs1864039231,2
    --46721847(+) GATGCC/TTAGTT 2 -- int10--------
    rs1392901371,2
    C--46721892(+) TTTATC/TAAAAG 2 -- int10--------
    rs1428998751,2
    --46722045(+) TCATGG/TTGAAT 2 -- int10--------
    rs1885542231,2
    --46722047(+) ATGGTA/GAATTA 2 -- int10--------
    rs1811742821,2
    --46722056(+) TAACTG/TTTTAA 2 -- int10--------
    rs1854394621,2
    --46722198(+) GAATGC/TATTAG 2 -- int10--------
    rs1127972511,2
    C,F--46722344(+) TTATTA/GATTTA 2 -- int11Minor allele frequency- G:0.00CSA 1
    rs1898033161,2
    --46722456(+) TTTGTG/TTGCAT 2 -- int10--------
    rs1400551501,2
    C--46722619(+) AACCAA/GCTTTT 2 -- int10--------
    rs1840910031,2
    C--46722702(+) GCTAGC/TTTTTG 2 -- int10--------
    rs1422804561,2
    --46722856(+) ACCTCC/TGCCTC 2 -- int10--------
    rs1872072881,2
    --46722857(+) CCTCCA/GCCTCC 2 -- int10--------
    rs1508165441,2
    --46723064(+) CACCAC/TGCCTG 2 -- int10--------
    rs1916289251,2
    --46723114(+) AACTTA/TCCTCT 2 -- int10--------
    rs1835458361,2
    C--46723185(+) TTTTAA/CATGTT 2 -- int10--------
    rs1870915681,2
    --46723370(+) GTGGCA/GTAATT 2 -- int10--------
    rs790964811,2
    C--46723469(+) ACACC-/TGGCTG 2 -- int10--------
    rs1918005321,2
    --46723548(+) ACTCCC/TAGGCT 2 -- int10--------
    rs1500572501,2
    --46723579(+) GACCTC/TCCAAA 2 -- int10--------
    rs59062991,2
    C,H--46723822(+) CTAGGT/GACTTT 2 -- int16Minor allele frequency- G:0.00NS EA NA 422
    rs1824818141,2
    --46723859(+) CTTTCC/TTCTTA 2 -- int10--------
    rs1868035561,2
    --46724405(+) GTTCAA/TCTCCT 2 -- int10--------
    rs1910924691,2
    C--46724575(+) TACTTA/GGAACA 2 -- int10--------
    rs1855832721,2
    --46724645(+) ACTTTC/GTTGCT 2 -- int10--------
    rs59063001,2
    C,F,H--46725807(+) ACTGCG/AGTGTT 2 -- int110Minor allele frequency- A:0.05NS EA NA 1078
    rs1425368381,2
    C--46725827(+) GAGCCC/TGGAGG 2 -- int10--------
    rs1904885441,2
    --46726091(+) GTTTTA/GGATAT 2 -- int10--------
    rs1929408341,2
    --46726122(+) TATATA/GGGCAA 2 -- int10--------
    rs1447784901,2
    C--46726127(+) AGGCAA/GTATCA 2 -- int10--------
    rs1853952761,2
    --46726253(+) GTCCAA/TGTCCT 2 -- int10--------
    rs1890081631,2
    --46726558(+) GGGTCA/GGTGAA 2 -- int10--------
    rs1814035441,2
    --46726563(+) GGTGAA/GAGTTG 2 -- int10--------
    rs1475919001,2
    --46726593(+) AAGATC/TAAGAT 2 -- int10--------
    rs1841525321,2
    --46726708(+) TGAAAA/GTGCCT 2 -- int10--------
    rs1883022561,2
    --46727061(+) AAGATA/GGTGTC 2 -- int10--------
    rs1490507771,2
    --46727279(+) CCTTTC/GTTCTA 2 -- int10--------
    rs1807164161,2
    C--46727600(+) GGTTTC/TGCCAT 2 -- int10--------
    rs1872705521,2
    --46727656(+) GCCTTG/TGCCTC 2 -- int10--------
    rs1921731721,2
    --46728206(+) TAAGCA/GGAGGT 2 -- int10--------
    rs1820197931,2
    --46728244(+) CATATA/TGTTTT 2 -- int10--------
    rs31261371,2
    C,F,A,H--46728459(+) cattcG/Ataaaa 2 -- int118Minor allele frequency- A:0.13NS EA NA WA CSA 1864
    rs1860097131,2
    --46728628(+) TATACC/GACAAA 2 -- int10--------
    rs1904707091,2
    --46728844(+) TAGAAA/GCGTAT 2 -- int10--------
    rs1404119021,2
    C--46728960(+) TAATAC/TTCCAT 2 -- int10--------
    rs1455517691,2
    --46729007(+) AGCAGA/GTGGGT 2 -- int10--------
    rs112914581,2
    C--46729523(+) TTTTT-/TATTTT 2 -- int10--------
    rs1868494311,2
    C--46729831(+) AGTGAA/GACTCC 2 -- int10--------
    rs78780531,2
    C--46729834(+) gagacC/Tccgtc 2 -- int10--------
    rs1826894271,2
    C--46729900(+) TTACTC/TGGGAG 2 -- int10--------
    rs1459895841,2
    --46730118(+) AATACC/GATTTG 2 -- int10--------
    rs1875295341,2
    --46730132(+) ATAAGA/GCCTCT 2 -- int10--------
    rs1388256911,2
    --46730343(+) CAATTA/TATTAG 2 -- int10--------
    rs1932870551,2
    --46730712(+) ATCAAC/TCAAAT 2 -- int10--------
    rs1855132781,2
    --46730875(+) CAACAA/GATTTC 2 -- int10--------
    rs1876708801,2
    --46730935(+) ATCCCA/CAAAAA 2 -- int10--------
    rs1115163531,2
    C,F--46731162(+) ACTTTC/GGGTTT 2 -- int11Minor allele frequency- G:0.00CSA 1
    rs1446954111,2
    --46731207(+) TTAGAC/TTATTC 2 -- int10--------
    rs1485051521,2
    --46731240(+) CTCATA/GTAAGC 2 -- int10--------
    rs1457101071,2
    --46731249(+) GCATTC/TAGTGC 2 -- int10--------
    rs31261381,2
    C,F,H--46731289(+) gttacG/Acccca 2 -- int112Minor allele frequency- A:0.00NS EA WA NA CSA 710
    rs732019031,2
    C--46731295(+) CCCCAC/GAAGTT 2 -- int10--------
    rs59055761,2
    C--46731576(+) CACTGT/CGCCCT 2 -- int11Minor allele frequency- C:0.00NA 1
    rs59063021,2
    H--46731661(+) GCTTAG/ATTTCC 2 -- int14Minor allele frequency- A:0.00NS EA 418
    rs59529741,2
    C,F,A,H--46731758(+) tggagG/Tgcagt 2 -- int14Minor allele frequency- T:0.50NA WA 8
    rs1112574931,2
    C,F--46731853(+) GGCATA/GTGCCA 2 -- int11Minor allele frequency- G:0.00NA 1
    rs1919732891,2
    --46732005(+) CCAGCC/TGTCTT 2 -- int10--------
    rs1842149211,2
    --46732359(+) GCTTTA/GTGTTC 2 -- int10--------
    rs1885456491,2
    --46732360(+) CTTTGA/TGTTCT 2 -- int10--------
    rs1809550161,2
    --46732382(+) TTATGA/TGGTGC 2 -- int10--------
    rs1846052201,2
    --46732384(+) ATGTGA/GTGCAT 2 -- int10--------
    rs1488244881,2
    --46732615(+) CAATCA/GTAGCT 2 -- int10--------
    rs1891211731,2
    --46732803(+) GGGAAC/GTTTGC 2 -- int10--------
    rs1451972631,2
    C--46733306(+) GTTAAA/CAGAAT 2 -- int10--------
    rs1825721061,2
    --46733564(+) GTTAAC/TGAAAG 2 -- int10--------
    rs1136856091,2
    C--46733633(+) AAACCG/AAAAAC 2 -- int11Minor allele frequency- A:0.00CSA 1
    rs732019041,2
    C--46733817(+) AAAGTA/GACCAT 2 -- int10--------
    rs1410850691,2
    --46733862(+) ATTGAC/TTGTTC 2 -- int10--------
    rs1158220541,2
    C--46733949(+) AAGATA/CAAAGG 2 -- int10--------
    rs1814091371,2
    --46734237(+) GGATGA/GTTTTC 2 -- int10--------
    rs1855487201,2
    --46734300(+) ATTTCC/TTTCTG 2 -- int10--------
    rs1448050931,2
    --46734586(+) AACTAC/TTCCTT 2 -- int10--------
    rs1482416791,2
    --46734767(+) ACAGGA/CAGGTA 2 -- int10--------
    rs1915232671,2
    --46734792(+) AGCAAA/GGAAGG 2 -- int10--------
    rs1829198801,2
    --46734828(+) ATCAAA/CAAAAA 2 -- int10--------
    rs1414892371,2
    C--46734919(+) CTTCCC/TACCTT 2 -- int10--------
    rs1880259771,2
    --46735047(+) ACCTCC/TAAAAT 2 -- int10--------
    rs1508497521,2
    --46735176(+) ATCTTA/GTTGTC 2 -- int10--------
    rs1381850351,2
    --46735310(+) ATCAAA/GGCCAA 2 -- int10--------
    rs1438448571,2
    C--46735324(+) AGCCCG/TCCACA 2 -- int10--------
    rs1907659721,2
    --46735686(+) CGAGAA/GTGAGT 2 -- int10--------
    rs125570131,2
    C,A,H--46735808(+) TGGTCC/TTAAGT 2 -- int15Minor allele frequency- T:0.00NS EA 594
    rs1833758911,2
    --46735922(+) ATTCAC/TTGAAT 2 -- int10--------
    rs1472371481,2
    --46736393(+) TTTTAA/TTGGAA 2 -- int10--------
    rs1877290211,2
    --46736466(+) AAAATG/TTAGTG 2 -- int10--------
    rs1922242971,2
    --46736706(+) AGGTGA/GCTTCT 2 -- int10--------
    rs736302461,2
    C,F--46736811(+) TCTCAA/TACTCT 2 -- int11Minor allele frequency- T:0.00WA 2
    rs734802371,2
    C,F--46737047(+) GAGGAC/TCATCA 2 -- int11Minor allele frequency- T:0.50WA 2
    rs2004646771,2
    --46737170(+) GCCTT-/AAAAAA 2 -- int10--------
    rs1448047961,2
    --46737186(+) AATTTC/GTATCT 2 -- int10--------
    rs1485579021,2
    --46737216(+) TGGCCC/TCAATT 2 -- int10--------
    rs1844282781,2
    --46737253(+) TGCTCC/TTTGAA 2 -- int10--------
    rs1421389371,2
    --46737599(+) ATGAAC/GTAAGT 2 -- int10--------
    rs1511716141,2
    C--46737973(+) CTGCAA/GCCAGT 2 -- int10--------
    rs1998121001,2
    --46738552(+) ATACA-/TTTTTT 2 -- int10--------
    rs1882917081,2
    --46738723(+) TACACA/GGCGAA 2 -- int10--------
    rs1929865291,2
    --46739031(+) GAGGCA/GCAGGT 2 -- int1