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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PHF15 Gene

protein-coding   GIFtS: 50
GCID: GC05P133860

PHD finger protein 15

  Search for PHF15
in our new
 Human Malady Compendium 
Biological research products
for PHF15
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
PHD Finger Protein 151 2 3
KIAA02391 3
JADE22 3
Protein Jade-22

External Ids:    HGNC: 229841   Entrez Gene: 233382   Ensembl: ENSG000000431437   OMIM: 6105155   UniProtKB: Q9NQC13   
ORGUL members:         
NONCODE:n340631    

Export aliases for PHF15 gene to outside databases

Previous GC identifers: GC05P133892 GC05P133937 GC05P133889 GC05P129048


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: JADE2_HUMAN, Q9NQC1
Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity
toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PHF15 gene promoter:
         CHOP-10   AREB6   AP-2beta   CUTL1   AP-2gamma   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPHF15 promoter sequence
   Search SABiosciences Chromatin IP Primers for PHF15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PHF15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.1   Ensembl cytogenetic band:  5q31.1   HGNC cytogenetic band: 5q31.2

PHF15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PHF15 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P133860:  view genomic region     (about GC identifiers)

Start:
133,860,003 bp from pter      End:
133,918,918 bp from pter
Size:
58,916 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: JADE2_HUMAN, Q9NQC1 (See protein sequence)
Recommended Name: Protein Jade-2  
Size: 790 amino acids; 87466 Da
Subunit: Component of the HBO1 complex composed at least of ING4 or ING5, MYST2/HBO1, MEAF6, and one of PHF15, PHF16
and PHF17
Sequence caution: Sequence=BAA13245.2; Type=Erroneous initiation; Sequence=BAB84949.1; Type=Frameshift; Positions=11;
Sequence=CAB94935.1; Type=Erroneous initiation;
Secondary accessions: Q6IE80 Q8TEK0 Q92513 Q96GQ6
Alternative splicing: 3 isoforms:  Q9NQC1-1   Q9NQC1-2   Q9NQC1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PHF15: NX_Q9NQC1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NQC1

  • PHF15 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056103.4  
    ENSEMBL proteins: 
     ENSP00000422991   ENSP00000282605   ENSP00000354425   ENSP00000384671   ENSP00000378451  
     ENSP00000406189   ENSP00000396026   ENSP00000393804   ENSP00000409961  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PHF15

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000123histone acetyltransferase complex IDA16387653


    PHF15 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for PHF15


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PHF15 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR001965 Znf_PHD
     IPR013083 Znf_RING/FYVE/PHD
     IPR019786 Zinc_finger_PHD-type_CS
     IPR011011 Znf_FYVE_PHD
     IPR019542 Enhancer_polycomb-like_N

    Graphical View of Domain Structure for InterPro Entry Q9NQC1

    ProtoNet protein and cluster: Q9NQC1

    UniProtKB/Swiss-Prot: JADE2_HUMAN, Q9NQC1
    Similarity: Belongs to the JADE family
    Similarity: Contains 1 PHD-type zinc finger


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: JADE2_HUMAN, Q9NQC1
    Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity
    toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo

    miRNA
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    hsa-miR-193a-3p hsa-miR-520f hsa-miR-300 hsa-miR-128 hsa-miR-3916 hsa-miR-192* hsa-miR-92b hsa-miR-4273
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PHF15

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--


    PHF15 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for PHF15:
     Increased cell death HMECs cel  Synthetic lethal with Ras  Synthetic lethal with c-Myc af 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PHF15

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/8 Interacting proteins for PHF15 (Q9NQC13 ENSP000003784514) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ING4Q9UNL43, ENSP000003800244I2D: score=1 STRING: ENSP00000380024
    KAT7O952513, ENSP000002590214I2D: score=1 STRING: ENSP00000259021
    ING5Q8WYH83, ENSP000003221424I2D: score=1 STRING: ENSP00000322142
    PACSIN1Q9BY113, ENSP000002444584I2D: score=3 STRING: ENSP00000244458
    ZBTB3Q9H5J03, ENSP000003782864I2D: score=1 STRING: ENSP00000378286
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043966histone H3 acetylation IDA16387653
    GO:0043981histone H4-K5 acetylation IDA16387653
    GO:0043982histone H4-K8 acetylation IDA16387653
    GO:0043983histone H4-K12 acetylation IDA16387653
    GO:0043984NOT histone H4-K16 acetylation IDA16387653


    PHF15 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PHF15
    Search CenterWatch for drugs/clinical trials and news about PHF15 / JADE2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PHF15 gene: 
    NM_015288.4  

    Unigene Cluster for PHF15:

    PHD finger protein 15
    Hs.732155  [show with all ESTs]
    Unigene Representative Sequence: D87076
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000512386 ENST00000282605(uc011cxt.1 uc003kzk.2) ENST00000515554
    ENST00000361895(uc003kzl.2 uc003kzm.2) ENST00000402835 ENST00000395003(uc003kzn.2 uc003kzo.1)
    ENST00000431355 ENST00000453515 ENST00000470876(uc003kzp.3) ENST00000430087
    ENST00000448712 ENST00000432594

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    hsa-miR-193a-3p hsa-miR-520f hsa-miR-300 hsa-miR-128 hsa-miR-3916 hsa-miR-192* hsa-miR-92b hsa-miR-4273
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    Additional cDNA sequence: 

    AJ251833.1 AK025001.1 AK056471.1 AK074123.1 AK124357.1 AK290471.1 AK292635.1 AK294327.1 
    BC004292.1 BC009307.2 BC021169.1 BC021962.2 D87076.2 

    12 DOTS entries:

    DT.101977553  DT.97844879  DT.100752416  DT.114871  DT.100747802  DT.95205558  DT.95369470  DT.100747803 
    DT.92428400  DT.120855119  DT.120855123  DT.95206283 

    24/177 AceView cDNA sequences (see all 177):

    BM468540 BC004292 BM853385 D87076 BU727470 BU634242 AA883064 AA322675 
    BX457885 AK056471 BU429624 BQ003353 AA553390 AW178043 BU166071 NM_015288 
    AA290973 AK124357 F06361 BM457892 BM552086 AL119840 BQ049838 BU156560 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for PHF15 (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b ^ 16a ·
    SP1:                          -     -     -           -           -                                                     -                             -         
    SP2:                                -     -           -           -                                                     -                             -     -   
    SP3:                                -     -           -           -                                                     -                             -         
    SP4:                                      -           -           -                                                     -                             -     -   
    SP5:                                                  -           -                                                                                             

    ExUns: 16b ^ 17
    SP1:  -         
    SP2:  -         
    SP3:            
    SP4:  -         
    SP5:            


    ECgene alternative splicing isoforms for PHF15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PHF15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGGGCTTCCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See PHF15 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PHF15

    SOURCE GeneReport for Unigene cluster: Hs.732155
        SABiosciences Custom PCR Arrays for PHF15
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PHF15 gene from 8/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Phf151 , 5 PHD finger protein 151, 5 88.03(n)1
    91.97(a)1
      11 (31.50 cM)5
    769011  NM_199299.31  NP_955003.21 
     518134555 
    chicken
    (Gallus gallus)
    Aves PHF151 PHD finger protein 15 73.46(n)
    75.58(a)
      416315  XM_414632.3  XP_414632.3 
    lizard
    (Anolis carolinensis)
    Reptilia PHF156
    --
    56(a)
    1 ↔ 1
    GL343223.1(198-50748)
    zebrafish
    (Danio rerio)
    Actinopterygii phf151 PHD finger protein 15 65.35(n)
    61.31(a)
      569359  XM_692739.5  XP_697831.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta rno6
    rhinoceros
    6(a)
    1 → many
    3L(187207-199762)
    worm
    (Caenorhabditis elegans)
    Secernentea phf-156
    Protein PHF-15, isoform b
    16(a)
    1 → many
    III(3322961-3331717)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G147406
    RING/FYVE/PHD zinc finger-containing protein
    21(a)
    1 → many
    3(4952004-4953423)
    rice
    (Oryza sativa)
    Liliopsida --
    PHD-finger domain containing protein, putative, ex...
    14(a)
    1 → many
    1(4430532-4432679)


    ENSEMBL Gene Tree for PHF15 (if available)
    TreeFam Gene Tree for PHF15 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PHF15 gene
    PHF172  BRPF12  BRD12  MLLT102  PHF142  PHF162  MLLT62  BRPF32  
    6 SIMAP similar genes for PHF15 using alignment to 8 protein entries:     JADE2_HUMAN (see all proteins):
    MLLT10    AF10    PHF17    PHF16    MLLT6    MLL/AF10 fusion

    PHF15 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/975 NCBI SNPs in PHF15 are shown (see all 975    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1396647531,2
    --133859866(+) TCCCCA/GGCTAG 1 -- us2k10--------
    rs773808221,2
    --133859893(+) TTGGAG/TCTTGA 1 -- us2k11Minor allele frequency- T:0.01EA 120
    rs2017910381,2
    --133859916(+) CCCAA-/CCCT  
            
    CCAGG
    1 -- us2k10--------
    rs1916820161,2
    --133859940(+) TCCTTC/TCTCGA 1 -- us2k10--------
    rs1679001,2
    --133859993(+) GCCCGA/CGGCTC 1 -- us2k10--------
    rs2004563591,2
    --133859997(+) GCGGC-/TCCGGG 1 -- us2k10--------
    rs3291171,2
    C,F,O,A,H,--133860101(+) GAGCGC/TACTGT 1 -- us2k113Minor allele frequency- T:0.26MN EA NS WA NA CSA 1148
    rs1830914021,2
    --133860151(+) GAGGAA/GGGGCG 1 -- us2k10--------
    rs114009341,2
    C,--133860235(+) TTTAA-/CCCTTT 1 -- us2k10--------
    rs339487381,2
    C--133860236(+) TAACC-/CTTTCG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PHF15 (133860003 - 133918918 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for PHF15
         1 CNV: 51573

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PHF15 for disorders           About MalaCards

    PHF15 for disorders           About GeneDecksing

    OMIM gene information: 610515    OMIM disorders: --

    Human Genome Epidemiology (HuGE) Navigator: PHF15 (2 documents)

    Export disorders for PHF15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PHF15 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with PHF15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. (PubMed id 16387653)1, 2 Doyon Y.... Cote J. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones. (PubMed id 12693554)1, 2 Jikuya H....Ohara O. (2003)
    4. Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development. (PubMed id 14612400)1, 2 Tzouanacou E.... Wilson V. (2003)
    5. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2 Nagase T....Nomura N. (1996)
    6. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    7. Thirty new loci for age at menarche identified by a m eta-analysis of genome-wide association studies. (PubMed id 21102462)1 Elks C.E....Murray A. (2010)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    9. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23338 HGNC: 22984 AceView: PHF15 Ensembl:ENSG00000043143 euGenes: HUgn23338
    ECgene: PHF15 H-InvDB: PHF15

    (According to HUGE)
    About This Section
    HUGE: KIAA0239

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PHF15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PHF15 gene:
    Search GeneIP for patents involving PHF15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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