Aliases for PHC3 Gene
External Ids for PHC3 Gene
Previous GeneCards Identifiers for PHC3 Gene
GeneCards Summary for PHC3 Gene
PHC3 (Polyhomeotic Homolog 3) is a Protein Coding gene. Among its related pathways are Cellular Senescence (REACTOME) and SUMOylation. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is PHC2.
UniProtKB/Swiss-Prot for PHC3 Gene
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.