Aliases for PHACTR1 Gene
Aliases for PHACTR1 Gene
External Ids for PHACTR1 Gene
- HGNC: 20990
- Entrez Gene: 221692
- Ensembl: ENSG00000112137
- OMIM: 608723
- UniProtKB: Q9C0D0
Previous HGNC Symbols for PHACTR1 Gene
- RPEL1
Previous GeneCards Identifiers for PHACTR1 Gene
- GC06P012826
- GC06P012827
Summaries for PHACTR1 Gene
-
The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
GeneCards Summary for PHACTR1 Gene
PHACTR1 (Phosphatase And Actin Regulator 1) is a Protein Coding gene. Diseases associated with PHACTR1 include Artery Disease and Deafness, Autosomal Dominant 31. GO annotations related to this gene include actin binding and protein phosphatase 1 binding. An important paralog of this gene is PHACTR3.
UniProtKB/Swiss-Prot for PHACTR1 Gene
-
Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PHACTR1 Gene
Genomics for PHACTR1 Gene
Regulatory Elements for PHACTR1 Gene
Enhancers for PHACTR1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH06G012748 | 1.1 | Ensembl ENCODE | 10.5 | +33.1 | 33107 | 1.5 | KLF1 MXI1 ZNF133 RBBP5 RAD21 ZFHX2 ZNF366 SCRT2 SMC3 MAFK | RPL15P3 PHACTR1 LOC105374935 LOC105374934 |
| GH06G013258 | 1.7 | FANTOM5 Ensembl ENCODE dbSUPER | 6.5 | +544.3 | 544326 | 4.3 | HDGF PKNOX1 TBL1XR1 BMI1 EGR1 CBX5 ZNF207 RELB ETV6 IKZF2 | TBC1D7 RNU1-11P ENSG00000215022 PHACTR1 GFOD1 RANBP9 PIR62166 LOC105374933 |
| GH06G012893 | 1 | Ensembl ENCODE | 8.6 | +177.4 | 177353 | 0.6 | HNRNPUL1 CTCF PKNOX1 KLF1 MXI1 RAD21 ZBTB48 ZNF143 SMC3 KLF7 | PHACTR1 LOC105374934 GC06M012692 |
| GH06G012638 | 0.8 | FANTOM5 | 10.1 | -78.5 | -78505 | 0.1 | CTCF JUN INSM2 RAD21 ZEB1 FOSL1 ZBTB48 ZNF366 ZNF143 SMC3 | EDN1 PHACTR1 LOC101928309 |
| GH06G012874 | 0.4 | ENCODE | 16.3 | +158.6 | 158593 | 1.0 | ZNF316 MAFK | PHACTR1 LOC105374934 GC06M012692 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around PHACTR1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the PHACTR1 gene promoter:
Regulatory Element Products
Genomic Location for PHACTR1 Gene
- Chromosome:
- 6
- Start:
- 12,716,606 bp from pter
- End:
- 13,290,484 bp from pter
- Size:
- 573,879 bases
- Orientation:
- Plus strand
Genomic View for PHACTR1 Gene
Genes around PHACTR1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p24.1 by Ensembl
- 6p24.1 by Entrez Gene
- 6p24.1 by HGNC
PHACTR1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PHACTR1 Gene
Proteins for PHACTR1 Gene
-
Protein details for PHACTR1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9C0D0-PHAR1_HUMAN
- Recommended name:
- Phosphatase and actin regulator 1
- Protein Accession:
- Q9C0D0
- A8K1V2
- Q3MJ93
- Q5JSJ2
Protein attributes for PHACTR1 Gene
- Size:
- 580 amino acids
- Molecular mass:
- 66308 Da
- Quaternary structure:
-
- Interacts (via RPEL repeats) with ACTA1 and PPP1CA; ACTA1 and PPP1CA compete for the same binding site.
- SequenceCaution:
-
- Sequence=BAB21824.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for PHACTR1 Gene
Post-translational modifications for PHACTR1 Gene
Other Protein References for PHACTR1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001229577.1
- NP_001309237.1
- NP_001309238.1
- NP_001309239.1
- NP_001309240.1
- NP_001309241.1
- NP_001309242.1
- NP_001309243.1
- NP_112210.1
- XP_005248991.1
- XP_016865941.1
- XP_016865943.1
- XP_016865944.1
- XP_016865945.1
- XP_016865946.1
- XP_016865947.1
- XP_016865948.1
- XP_016865949.1
- XP_016865950.1
- XP_016865951.1
- XP_016865952.1
- XP_016865953.1
- XP_016865954.1
- XP_016865955.1
- XP_016865956.1
- XP_016865958.1
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for PHACTR1
- Novus Biologicals Antibodies for PHACTR1
- Invitrogen Antibodies for PHACTR1
- GeneTex PHACTR1 antibody for PHACTR1
-
Santa Cruz Biotechnology (SCBT) Antibodies for PHACTR1
Protein Products
-
OriGene Purified Proteins for PHACTR1
- Search Origene for MassSpec and Protein Over-expression Lysates for PHACTR1
- Origene Custom Protein Services for PHACTR1
- Search GeneTex for Proteins for PHACTR1
No data available for DME Specific Peptides for PHACTR1 Gene
Domains & Families for PHACTR1 Gene
Gene Families for PHACTR1 Gene
Protein Domains for PHACTR1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for PHACTR1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9C0D0UniProtKB/Swiss-Prot:
PHAR1_HUMAN :- Binds three actin monomers via the three C-terminal RPEL repeats.
- Belongs to the phosphatase and actin regulator family.
- Domain:
-
- Binds three actin monomers via the three C-terminal RPEL repeats.
- Family:
-
- Belongs to the phosphatase and actin regulator family.
Function for PHACTR1 Gene
Molecular function for PHACTR1 Gene
- UniProtKB/Swiss-Prot Function:
- Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated by VEGFA.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003779 | actin binding | ISS | -- |
| GO:0004864 | protein phosphatase inhibitor activity | IEA | -- |
| GO:0008157 | protein phosphatase 1 binding | IEA | -- |
| GO:0019888 | protein phosphatase regulator activity | IEA | -- |
Phenotypes for PHACTR1 Gene
- GenomeRNAi human phenotypes for PHACTR1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PHACTR1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for PHACTR1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PHACTR1 gene
- Search ViGene Biosciences for PHACTR1
CRISPR Products
-
OriGene CRISPR knockouts for PHACTR1
-
Santa Cruz Biotechnology (SCBT) CRISPR for PHACTR1
- GenScript: Design CRISPR guide RNA sequences for PHACTR1
miRNA for PHACTR1 Gene
- miRTarBase miRNAs that target PHACTR1
miRNA Products
- Search ViGene Biosciences for PHACTR1
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for PHACTR1
- Browse OriGene Inhibitory RNA Products For PHACTR1
-
ViGene Biosciences ready-to-package AAV shRNAs for PHACTR1 gene
Clone Products
-
OriGene ORF clones in human for PHACTR1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PHACTR1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PHACTR1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for PHACTR1
-
ViGene Biosciences adenoviral particle packaged cDNA for PHACTR1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PHACTR1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PHACTR1 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PHACTR1 Gene
Localization for PHACTR1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PHACTR1 Gene
- Cytoplasm. Cell junction, synapse. Nucleus. Note=Enriched at synapses (By similarity). Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity). {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | ISS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | ISS | -- |
| GO:0030054 | cell junction | IEA | -- |
| GO:0045202 | synapse | IEA | -- |
Pathways & Interactions for PHACTR1 Gene
No Data Available
Interacting Proteins for PHACTR1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0031032 | actomyosin structure organization | IMP | 22976292 |
| GO:0031532 | actin cytoskeleton reorganization | IEA,ISS | -- |
| GO:0043086 | negative regulation of catalytic activity | IEA | -- |
| GO:0043149 | stress fiber assembly | IMP | 22976292 |
| GO:0048870 | cell motility | IMP | 22976292 |
No data available for Pathways by source and SIGNOR curated interactions for PHACTR1 Gene
Transcripts for PHACTR1 Gene
mRNA/cDNA for PHACTR1 Gene
- (26) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (74) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for PHACTR1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for PHACTR1
-
Santa Cruz Biotechnology (SCBT) CRISPR for PHACTR1
- GenScript: Design CRISPR guide RNA sequences for PHACTR1
miRNA Products
- Search ViGene Biosciences for PHACTR1
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for PHACTR1
- Browse OriGene Inhibitory RNA Products For PHACTR1
-
ViGene Biosciences ready-to-package AAV shRNAs for PHACTR1 gene
Clone Products
-
OriGene ORF clones in human for PHACTR1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PHACTR1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PHACTR1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for PHACTR1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Melanocytes (Integumentary System)
- Epidermis (Integumentary System)
- Brain (Nervous System)
- Epiblast (Early Embryonic Tissues)
- NULL (Integumentary System)
mRNA differential expression in normal tissues according to GTEx for PHACTR1 Gene
This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x5.6) and Brain - Frontal Cortex (BA9) (x4.2).
This gene is overexpressed in Frontal cortex (33.6) and Brain (30.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for PHACTR1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of PHACTR1 Gene:
PHACTR1SOURCE GeneReport for Unigene cluster for PHACTR1 Gene:
Hs.436996mRNA Expression by UniProt/SwissProt for PHACTR1 Gene:
Q9C0D0-PHAR1_HUMAN
Tissue specificity:
Detected in umbilical vein endothelial cells.
Evidence on tissue expression from TISSUES for PHACTR1 Gene
- Nervous system(4.3)
- Heart(2.6)
Primer Products
-
OriGene qPCR primer pairs for PHACTR1
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for PHACTR1 Gene
Orthologs for PHACTR1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PHACTR1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | PHACTR1 34 |
|
||
| dog (Canis familiaris) |
Mammalia | PHACTR1 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Phactr1 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Phactr1 34 16 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PHACTR1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | PHACTR1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | PHACTR1 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | phactr1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100334776 34 |
|
- Species where no ortholog for PHACTR1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for PHACTR1 Gene
(3) SIMAP similar genes for PHACTR1 Gene using alignment to 10 proteins:
Variants for PHACTR1 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000004832 | -- | 12,979,038(+) | ATGAT(G/T)GTTGA | intron-variant | |
| rs1000008114 | -- | 13,084,596(+) | GGAAG(C/T)AATAA | intron-variant | |
| rs1000026902 | -- | 13,187,100(+) | AATGG(C/T)GAGCA | intron-variant | |
| rs1000036141 | -- | 13,225,149(+) | TTATC(A/G)GGGCA | intron-variant | |
| rs1000048431 | -- | 12,790,557(+) | AGCTC(C/G)TTTAG | intron-variant |
Gene Damage Index Score:
0.56;
12.00% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for PHACTR1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PHACTR1 Gene
Disorders for PHACTR1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| artery disease |
|
|
| deafness, autosomal dominant 31 |
|
|
| deafness, autosomal dominant 21 |
|
|
| myocardial infarction |
|
|
| deafness, autosomal dominant 13 |
|
|
Search PHACTR1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for PHACTR1
No data available for UniProtKB/Swiss-Prot and Genatlas for PHACTR1 Gene
Publications for PHACTR1 Gene
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 64
- Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells. (PMID: 21939755) Allain B. … Lepelletier Y. (Cell. Signal. 2012) 3 4 64
- A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. (PMID: 21378988) (Nat. Genet. 2011) 3 46 64
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. (PMID: 21378990) Schunkert H. … Samani N.J. (Nat. Genet. 2011) 3 46 64
- Depletion of the novel protein PHACTR-1 from human endothelial cells abolishes tube formation and induces cell death receptor apoptosis. (PMID: 21798305) Jarray R. … Raynaud F. (Biochimie 2011) 3 4 64
Products for PHACTR1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for PHACTR1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PHACTR1
- Search Origene for MassSpec and Protein Over-expression Lysates for PHACTR1
- Origene Custom Protein Services for PHACTR1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for PHACTR1
- Browse OriGene Inhibitory RNA Products For PHACTR1
- OriGene qPCR primer pairs for PHACTR1
- OriGene CRISPR knockouts for PHACTR1
- OriGene ORF clones in human for PHACTR1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PHACTR1
- GenScript: Next-day shipping cDNA ORF clone for PHACTR1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for PHACTR1
- GenScript Custom Assay Services for PHACTR1
- GenScript Custom overexpressing Cell Line Services for PHACTR1
- GenScript: Design CRISPR guide RNA sequences for PHACTR1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for PHACTR1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for PHACTR1
- Novus Biologicals proteins and lysates for PHACTR1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for PHACTR1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- GeneTex PHACTR1 antibody for PHACTR1
- Search GeneTex for Proteins for PHACTR1
- ViGene Biosciences adenoviral particle packaged cDNA for PHACTR1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PHACTR1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PHACTR1 gene
- Search ViGene Biosciences for PHACTR1
- Santa Cruz Biotechnology (SCBT) Antibodies for PHACTR1
- Search Santa Cruz Biotechnology (SCBT) for PHACTR1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PHACTR1
- Horizon Cell Lines for PHACTR1
- Cyagen custom Knockout/knockin (KOKI) mouse models for PHACTR1
- VectorBuilder custom plasmid, inducible vectors for PHACTR1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PHACTR1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for PHACTR1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer